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Items: 21


Crosstalk Between T Lymphocytes and Lung Fibroblasts: Generation of a Hyaluronan-Enriched Extracellular Matrix Adhesive for Monocytes.

Gaucherand L, Falk BA, Evanko SP, Workman G, Chan CK, Wight TN.

J Cell Biochem. 2017 Aug;118(8):2118-2130. doi: 10.1002/jcb.25842. Epub 2017 Apr 18.


Modified High-Molecular-Weight Hyaluronan Promotes Allergen-Specific Immune Tolerance.

Gebe JA, Yadava K, Ruppert SM, Marshall P, Hill P, Falk BA, Sweere JM, Han H, Kaber G, Harten IA, Medina C, Mikecz K, Ziegler SF, Balaji S, Keswani SG, Perez VA, Butte MJ, Nadeau K, Altemeier WA, Fanger N, Bollyky PL.

Am J Respir Cell Mol Biol. 2017 Jan;56(1):109-120. doi: 10.1165/rcmb.2016-0111OC. Erratum in: Am J Respir Cell Mol Biol. 2017 Aug;57(2):259.


Regulatory T Cells Resist Cyclosporine-Induced Cell Death via CD44-Mediated Signaling Pathways.

Ruppert SM, Falk BA, Long SA, Bollyky PL.

Int J Cell Biol. 2015;2015:614297. doi: 10.1155/2015/614297. Epub 2015 Sep 10.


Inhibition of hyaluronan synthesis restores immune tolerance during autoimmune insulitis.

Nagy N, Kaber G, Johnson PY, Gebe JA, Preisinger A, Falk BA, Sunkari VG, Gooden MD, Vernon RB, Bogdani M, Kuipers HF, Day AJ, Campbell DJ, Wight TN, Bollyky PL.

J Clin Invest. 2015 Oct 1;125(10):3928-40. doi: 10.1172/JCI79271. Epub 2015 Sep 14.


Use of versican variant V3 and versican antisense expression to engineer cultured human skin containing increased content of insoluble elastin.

Merrilees MJ, Falk BA, Zuo N, Dickinson ME, May BC, Wight TN.

J Tissue Eng Regen Med. 2017 Jan;11(1):295-305. doi: 10.1002/term.1913. Epub 2014 Jun 19.


IL-10 induction from implants delivering pancreatic islets and hyaluronan.

Bollyky PL, Vernon RB, Falk BA, Preisinger A, Gooden MD, Nepom GT, Gebe JA.

J Diabetes Res. 2013;2013:342479. doi: 10.1155/2013/342479. Epub 2013 Jul 22.


ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors.

Bollyky PL, Wu RP, Falk BA, Lord JD, Long SA, Preisinger A, Teng B, Holt GE, Standifer NE, Braun KR, Xie CF, Samuels PL, Vernon RB, Gebe JA, Wight TN, Nepom GT.

Proc Natl Acad Sci U S A. 2011 May 10;108(19):7938-43. doi: 10.1073/pnas.1017360108. Epub 2011 Apr 25.


Recurrence of type 1 diabetes after simultaneous pancreas-kidney transplantation, despite immunosuppression, is associated with autoantibodies and pathogenic autoreactive CD4 T-cells.

Vendrame F, Pileggi A, Laughlin E, Allende G, Martin-Pagola A, Molano RD, Diamantopoulos S, Standifer N, Geubtner K, Falk BA, Ichii H, Takahashi H, Snowhite I, Chen Z, Mendez A, Chen L, Sageshima J, Ruiz P, Ciancio G, Ricordi C, Reijonen H, Nepom GT, Burke GW 3rd, Pugliese A.

Diabetes. 2010 Apr;59(4):947-57. doi: 10.2337/db09-0498. Epub 2010 Jan 19.


Evidence for molecular mimicry between human T cell epitopes in rotavirus and pancreatic islet autoantigens.

Honeyman MC, Stone NL, Falk BA, Nepom G, Harrison LC.

J Immunol. 2010 Feb 15;184(4):2204-10. doi: 10.4049/jimmunol.0900709. Epub 2010 Jan 18.


CD44 costimulation promotes FoxP3+ regulatory T cell persistence and function via production of IL-2, IL-10, and TGF-beta.

Bollyky PL, Falk BA, Long SA, Preisinger A, Braun KR, Wu RP, Evanko SP, Buckner JH, Wight TN, Nepom GT.

J Immunol. 2009 Aug 15;183(4):2232-41. doi: 10.4049/jimmunol.0900191. Epub 2009 Jul 27.


Restricted autoantigen recognition associated with deletional and adaptive regulatory mechanisms.

Gebe JA, Yue BB, Unrath KA, Falk BA, Nepom GT.

J Immunol. 2009 Jul 1;183(1):59-65. doi: 10.4049/jimmunol.0804046. Epub 2009 Jun 17.


Intact extracellular matrix and the maintenance of immune tolerance: high molecular weight hyaluronan promotes persistence of induced CD4+CD25+ regulatory T cells.

Bollyky PL, Falk BA, Wu RP, Buckner JH, Wight TN, Nepom GT.

J Leukoc Biol. 2009 Sep;86(3):567-72. doi: 10.1189/jlb.0109001. Epub 2009 Apr 28. Review.


The toll-like receptor signaling molecule Myd88 contributes to pancreatic beta-cell homeostasis in response to injury.

Bollyky PL, Bice JB, Sweet IR, Falk BA, Gebe JA, Clark AE, Gersuk VH, Aderem A, Hawn TR, Nepom GT.

PLoS One. 2009;4(4):e5063. doi: 10.1371/journal.pone.0005063. Epub 2009 Apr 1.


Autoreactive human T-cell receptor initiates insulitis and impaired glucose tolerance in HLA DR4 transgenic mice.

Gebe JA, Unrath KA, Yue BB, Miyake T, Falk BA, Nepom GT.

J Autoimmun. 2008 Jun;30(4):197-206. Epub 2007 Oct 18.


Age-dependent loss of tolerance to an immunodominant epitope of glutamic acid decarboxylase in diabetic-prone RIP-B7/DR4 mice.

Gebe JA, Unrath KA, Falk BA, Ito K, Wen L, Daniels TL, Lernmark A, Nepom GT.

Clin Immunol. 2006 Dec;121(3):294-304. Epub 2006 Sep 18.


Antibiotic-refractory Lyme arthritis is associated with HLA-DR molecules that bind a Borrelia burgdorferi peptide.

Steere AC, Klitz W, Drouin EE, Falk BA, Kwok WW, Nepom GT, Baxter-Lowe LA.

J Exp Med. 2006 Apr 17;203(4):961-71. Epub 2006 Apr 3.


The insulin A-chain epitope recognized by human T cells is posttranslationally modified.

Mannering SI, Harrison LC, Williamson NA, Morris JS, Thearle DJ, Jensen KP, Kay TW, Rossjohn J, Falk BA, Nepom GT, Purcell AW.

J Exp Med. 2005 Nov 7;202(9):1191-7. Epub 2005 Oct 31.


Low-avidity recognition by CD4+ T cells directed to self-antigens.

Gebe JA, Falk BA, Rock KA, Kochik SA, Heninger AK, Reijonen H, Kwok WW, Nepom GT.

Eur J Immunol. 2003 May;33(5):1409-17.


Tetramer-guided epitope mapping: rapid identification and characterization of immunodominant CD4+ T cell epitopes from complex antigens.

Novak EJ, Liu AW, Gebe JA, Falk BA, Nepom GT, Koelle DM, Kwok WW.

J Immunol. 2001 Jun 1;166(11):6665-70.


Peptide binding affinity and pH variation establish functional thresholds for activation of HLA-DQ-restricted T cell recognition.

Kwok WW, Reijonen H, Falk BA, Koelle DM, Nepom GT.

Hum Immunol. 1999 Jul;60(7):619-26.


Cloning of the human and murine interleukin-7 receptors: demonstration of a soluble form and homology to a new receptor superfamily.

Goodwin RG, Friend D, Ziegler SF, Jerzy R, Falk BA, Gimpel S, Cosman D, Dower SK, March CJ, Namen AE, et al.

Cell. 1990 Mar 23;60(6):941-51.


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