Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 179

1.

Synthesis and structure-activity evaluation of isatin-β-thiosemicarbazones with improved selective activity toward multidrug-resistant cells expressing P-glycoprotein.

Hall MD, Brimacombe KR, Varonka MS, Pluchino KM, Monda JK, Li J, Walsh MJ, Boxer MB, Warren TH, Fales HM, Gottesman MM.

J Med Chem. 2011 Aug 25;54(16):5878-89. doi: 10.1021/jm2006047. Epub 2011 Aug 1.

2.

Identification of compounds selectively killing multidrug-resistant cancer cells.

Türk D, Hall MD, Chu BF, Ludwig JA, Fales HM, Gottesman MM, Szakács G.

Cancer Res. 2009 Nov 1;69(21):8293-301. doi: 10.1158/0008-5472.CAN-09-2422. Epub 2009 Oct 20.

3.

Synthesis, activity, and pharmacophore development for isatin-beta-thiosemicarbazones with selective activity toward multidrug-resistant cells.

Hall MD, Salam NK, Hellawell JL, Fales HM, Kensler CB, Ludwig JA, Szakács G, Hibbs DE, Gottesman MM.

J Med Chem. 2009 May 28;52(10):3191-204. doi: 10.1021/jm800861c.

4.

Chronic lymphocytic leukemia antibodies with a common stereotypic rearrangement recognize nonmuscle myosin heavy chain IIA.

Chu CC, Catera R, Hatzi K, Yan XJ, Zhang L, Wang XB, Fales HM, Allen SL, Kolitz JE, Rai KR, Chiorazzi N.

Blood. 2008 Dec 15;112(13):5122-9. doi: 10.1182/blood-2008-06-162024. Epub 2008 Sep 23.

5.

Detection of venous thromboembolism by proteomic serum biomarkers.

Ganesh SK, Sharma Y, Dayhoff J, Fales HM, Van Eyk J, Kickler TS, Billings EM, Nabel EG.

PLoS One. 2007 Jun 20;2(6):e544.

6.

Multisite phosphorylation of adipocyte and hepatocyte phosphodiesterase 3B.

Lindh R, Ahmad F, Resjö S, James P, Yang JS, Fales HM, Manganiello V, Degerman E.

Biochim Biophys Acta. 2007 Apr;1773(4):584-92. Epub 2007 Jan 27.

7.

Selective toxicity of NSC73306 in MDR1-positive cells as a new strategy to circumvent multidrug resistance in cancer.

Ludwig JA, Szakács G, Martin SE, Chu BF, Cardarelli C, Sauna ZE, Caplen NJ, Fales HM, Ambudkar SV, Weinstein JN, Gottesman MM.

Cancer Res. 2006 May 1;66(9):4808-15.

8.
9.

2-Methyl-(1Z,3E)-butadiene-1,3,4-tricarboxylic acid, "isoprenetricarboxylic acid".

Goren MB, Sokoloski EA, Fales HM.

J Org Chem. 2005 Sep 2;70(18):7429-31.

PMID:
16122270
10.

Regulation of ASAP1 by phospholipids is dependent on the interface between the PH and Arf GAP domains.

Che MM, Boja ES, Yoon HY, Gruschus J, Jaffe H, Stauffer S, Schuck P, Fales HM, Randazzo PA.

Cell Signal. 2005 Oct;17(10):1276-88. Epub 2005 Feb 25.

PMID:
16038802
11.

Detection and characterization of the product of hydroethidine and intracellular superoxide by HPLC and limitations of fluorescence.

Zhao H, Joseph J, Fales HM, Sokoloski EA, Levine RL, Vasquez-Vivar J, Kalyanaraman B.

Proc Natl Acad Sci U S A. 2005 Apr 19;102(16):5727-32. Epub 2005 Apr 11. Erratum in: Proc Natl Acad Sci U S A. 2005 Jun 21;102(25):9086.

12.

Identification of carboxypeptidase N as an enzyme responsible for C-terminal cleavage of stromal cell-derived factor-1alpha in the circulation.

Davis DA, Singer KE, De La Luz Sierra M, Narazaki M, Yang F, Fales HM, Yarchoan R, Tosato G.

Blood. 2005 Jun 15;105(12):4561-8. Epub 2005 Feb 17.

13.

Method for isolating tight-binding inhibitors of rat lens aldose reductase.

Sun G, Ma Y, Gao X, König S, Fales HM, Kador PF.

Exp Eye Res. 2004 Dec;79(6):919-26.

PMID:
15642330
14.

Mass spectrometry analysis of recombinant human ZP3 expressed in glycosylation-deficient CHO cells.

Zhao M, Boja ES, Hoodbhoy T, Nawrocki J, Kaufman JB, Kresge N, Ghirlando R, Shiloach J, Pannell L, Levine RL, Fales HM, Dean J.

Biochemistry. 2004 Sep 28;43(38):12090-104.

PMID:
15379548
15.
16.
17.

Mutation of a conserved hydrophobic patch prevents incorporation of ZP3 into the zona pellucida surrounding mouse eggs.

Zhao M, Gold L, Dorward H, Liang LF, Hoodbhoy T, Boja E, Fales HM, Dean J.

Mol Cell Biol. 2003 Dec;23(24):8982-91.

18.

Roles of TRP14, a thioredoxin-related protein in tumor necrosis factor-alpha signaling pathways.

Jeong W, Chang TS, Boja ES, Fales HM, Rhee SG.

J Biol Chem. 2004 Jan 30;279(5):3151-9. Epub 2003 Nov 7.

19.

Differential processing of stromal-derived factor-1alpha and stromal-derived factor-1beta explains functional diversity.

De La Luz Sierra M, Yang F, Narazaki M, Salvucci O, Davis D, Yarchoan R, Zhang HH, Fales H, Tosato G.

Blood. 2004 Apr 1;103(7):2452-9. Epub 2003 Oct 2.

20.

Specific regulation of the adaptor protein complex AP-3 by the Arf GAP AGAP1.

Nie Z, Boehm M, Boja ES, Vass WC, Bonifacino JS, Fales HM, Randazzo PA.

Dev Cell. 2003 Sep;5(3):513-21.

21.

Structural characterization of native mouse zona pellucida proteins using mass spectrometry.

Boja ES, Hoodbhoy T, Fales HM, Dean J.

J Biol Chem. 2003 Sep 5;278(36):34189-202. Epub 2003 Jun 10.

22.

Reversible oxidative modification as a mechanism for regulating retroviral protease dimerization and activation.

Davis DA, Brown CA, Newcomb FM, Boja ES, Fales HM, Kaufman J, Stahl SJ, Wingfield P, Yarchoan R.

J Virol. 2003 Mar;77(5):3319-25.

23.

Attachment of neutrals during tandem mass spectrometry of sulfonic acid dyes and intermediates in an ion trap.

Weisz A, Andrzejewski D, Fales HM, Mandelbaum A.

J Mass Spectrom. 2002 Oct;37(10):1025-33.

PMID:
12375276
24.

Preparation of myristoylated Arf1 and Arf6 proteins.

Randazzo PA, Fales HM.

Methods Mol Biol. 2002;189:169-79. No abstract available.

PMID:
12094585
25.

Reversible oxidation of HIV-2 protease.

Davis DA, Newcomb FM, Moskovitz J, Fales HM, Levine RL, Yarchoan R.

Methods Enzymol. 2002;348:249-59. No abstract available.

PMID:
11885278
26.

Intramolecular cross-linking experiments on cytochrome c and ribonuclease A using an isotope multiplet method.

Pearson KM, Pannell LK, Fales HM.

Rapid Commun Mass Spectrom. 2002;16(3):149-59.

PMID:
11803535
27.

Oxidative modifications of kynostatin-272, a potent human immunodeficiency virus type 1 protease inhibitor: potential mechanism for altered activity in monocytes/macrophages.

Davis DA, Read-Connole E, Pearson K, Fales HM, Newcomb FM, Moskovitz J, Yarchoan R.

Antimicrob Agents Chemother. 2002 Feb;46(2):402-8.

28.

Reversible glutathionylation regulates actin polymerization in A431 cells.

Wang J, Boja ES, Tan W, Tekle E, Fales HM, English S, Mieyal JJ, Chock PB.

J Biol Chem. 2001 Dec 21;276(51):47763-6. Epub 2001 Oct 29.

30.

Overalkylation of a protein digest with iodoacetamide.

Boja ES, Fales HM.

Anal Chem. 2001 Aug 1;73(15):3576-82.

PMID:
11510821
31.

Novel chemistry of abdominal defensive glands of nymphalid butterfly Agraulis vanillae.

Ross GN, Fales HM, Lloyd HA, Jones T, Sokoloski EA, Marshall-Batty K, Blum MS.

J Chem Ecol. 2001 Jun;27(6):1219-28.

PMID:
11504024
32.

Electrospray mass spectra of three proprietary detergents.

Yang-Boja E, DeFilippes F, Fales HM.

Anal Biochem. 2000 Oct 15;285(2):205-10. Erratum in: Anal Biochem 2001 Feb 15;289(2):306.

PMID:
11017703
33.

Peptidylglycine-alpha-hydroxylating monooxygenase generates two hydroxylated products from its mechanism-based suicide substrate, 4-phenyl-3-butenoic acid.

Driscoll WJ, König S, Fales HM, Pannell LK, Eipper BA, Mueller GP.

Biochemistry. 2000 Jul 11;39(27):8007-16.

PMID:
10891082
34.

HIV-2 protease is inactivated after oxidation at the dimer interface and activity can be partly restored with methionine sulphoxide reductase.

Davis DA, Newcomb FM, Moskovitz J, Wingfield PT, Stahl SJ, Kaufman J, Fales HM, Levine RL, Yarchoan R.

Biochem J. 2000 Mar 1;346 Pt 2:305-11.

35.

Regulation of PTP1B via glutathionylation of the active site cysteine 215.

Barrett WC, DeGnore JP, König S, Fales HM, Keng YF, Zhang ZY, Yim MB, Chock PB.

Biochemistry. 1999 May 18;38(20):6699-705.

PMID:
10350489
36.

A gas chromatographic-mass spectral assay for the quantitative determination of oleamide in biological fluids.

Hanus LO, Fales HM, Spande TF, Basile AS.

Anal Biochem. 1999 May 15;270(1):159-66.

PMID:
10328778
37.
38.

Comment on the cylindrical capacitor electrospray interface.

König S, Fales HM, Haegele KD.

Anal Chem. 1998 Oct 15;70(20):4453-5.

PMID:
9796428
39.

ω-Phonetoxin-IIA: a calcium channel blocker from the spider Phoneutria nigriventer.

Cassola AC, Jaffe H, Fales HM, Afeche SC, Magnoli F, Cipolla-Neto J.

Pflugers Arch. 1998 Jul;436(4):545-52.

PMID:
9683727
41.

On-line microdialysis for mass spectrometry.

König S, Weiler S, Fales HM.

Biotechniques. 1998 May;24(5):712-4, 716. No abstract available.

PMID:
9591112
42.

Gradient-based automated protein folding.

König S, Fales HM.

Biotechniques. 1997 Dec;23(6):1010-2, 1014. No abstract available.

PMID:
9421627
43.

Determination of a native proteolytic site in myelin-associated glycoprotein.

Stebbins JW, Jaffe H, Fales HM, Möller JR.

Biochemistry. 1997 Feb 25;36(8):2221-6.

PMID:
9047323
44.

Rubber stoppers as sources of contaminants in electrospray analysis of peptides and proteins.

Zhang XK, Dutky RC, Fales HM.

Anal Chem. 1996 Sep 15;68(18):3288-9.

PMID:
8797388
45.

Regulation of HIV-1 protease activity through cysteine modification.

Davis DA, Dorsey K, Wingfield PT, Stahl SJ, Kaufman J, Fales HM, Levine RL.

Biochemistry. 1996 Feb 20;35(7):2482-8.

PMID:
8652592
46.

Countercurrent chromatographic analysis of ovalbumin obtained from various sources using the cross-axis coil planet centrifuge.

Shinomiya K, Inokuchi N, Gnabre JN, Muto M, Kabasawa Y, Fales HM, Ito Y.

J Chromatogr A. 1996 Feb 16;724(1-2):179-84.

PMID:
8819795
47.

Iron carboxylate oxygen-centered-triangle complexes detected during electrospray use of organic acid modifiers with a comment on the finnigan TSQ-700 electrospray inlet system.

Ijames CF, Dutky RC, Fales HM.

J Am Soc Mass Spectrom. 1995 Dec;6(12):1226-31. doi: 10.1016/1044-0305(95)00579-X.

PMID:
24214074
48.

The myristoylated amino terminus of ADP-ribosylation factor 1 is a phospholipid- and GTP-sensitive switch.

Randazzo PA, Terui T, Sturch S, Fales HM, Ferrige AG, Kahn RA.

J Biol Chem. 1995 Jun 16;270(24):14809-15.

49.

Cellular sterol accumulation stimulated by cholesterol 5 beta,6 beta-epoxide in J774 macrophages.

Cao J, Fales HM, Schaffner CP.

Proc Soc Exp Biol Med. 1995 Jun;209(2):195-204.

PMID:
7770472
50.

An observation and group dynamics model for teaching psychoanalytic psychotherapy.

Weber RL, Costikyan N, Fales H, Morgan S.

Acad Psychiatry. 1995 Mar;19(1):12-21. doi: 10.1007/BF03341414.

PMID:
24435569

Supplemental Content

Support Center