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Items: 7

1.

Long-term taxonomic and functional divergence from donor bacterial strains following fecal microbiota transplantation in immunocompromised patients.

Moss EL, Falconer SB, Tkachenko E, Wang M, Systrom H, Mahabamunuge J, Relman DA, Hohmann EL, Bhatt AS.

PLoS One. 2017 Aug 21;12(8):e0182585. doi: 10.1371/journal.pone.0182585. eCollection 2017.

2.

Zinc Chelation by a Small-Molecule Adjuvant Potentiates Meropenem Activity in Vivo against NDM-1-Producing Klebsiella pneumoniae.

Falconer SB, Reid-Yu SA, King AM, Gehrke SS, Wang W, Britten JF, Coombes BK, Wright GD, Brown ED.

ACS Infect Dis. 2015 Nov 13;1(11):533-43. doi: 10.1021/acsinfecdis.5b00033. Epub 2015 May 26.

PMID:
27623408
3.

Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice.

Shono Y, Docampo MD, Peled JU, Perobelli SM, Velardi E, Tsai JJ, Slingerland AE, Smith OM, Young LF, Gupta J, Lieberman SR, Jay HV, Ahr KF, Porosnicu Rodriguez KA, Xu K, Calarfiore M, Poeck H, Caballero S, Devlin SM, Rapaport F, Dudakov JA, Hanash AM, Gyurkocza B, Murphy GF, Gomes C, Liu C, Moss EL, Falconer SB, Bhatt AS, Taur Y, Pamer EG, van den Brink MRM, Jenq RR.

Sci Transl Med. 2016 May 18;8(339):339ra71. doi: 10.1126/scitranslmed.aaf2311.

4.

Metal-induced isomerization yields an intracellular chelator that disrupts bacterial iron homeostasis.

Falconer SB, Wang W, Gehrke SS, Cuneo JD, Britten JF, Wright GD, Brown ED.

Chem Biol. 2014 Jan 16;21(1):136-45. doi: 10.1016/j.chembiol.2013.11.007. Epub 2013 Dec 19.

5.

Antibiotics as probes of biological complexity.

Falconer SB, Czarny TL, Brown ED.

Nat Chem Biol. 2011 Jul;7(7):415-23. doi: 10.1038/nchembio.590. Review. No abstract available.

PMID:
21685879
6.

Combinations of antibiotics and nonantibiotic drugs enhance antimicrobial efficacy.

Ejim L, Farha MA, Falconer SB, Wildenhain J, Coombes BK, Tyers M, Brown ED, Wright GD.

Nat Chem Biol. 2011 Jun;7(6):348-50. doi: 10.1038/nchembio.559. Epub 2011 Apr 24.

PMID:
21516114
7.

New screens and targets in antibacterial drug discovery.

Falconer SB, Brown ED.

Curr Opin Microbiol. 2009 Oct;12(5):497-504. doi: 10.1016/j.mib.2009.07.001. Epub 2009 Aug 3. Review.

PMID:
19651534

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