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Items: 1 to 50 of 52

1.

Next-generation sequencing for the diagnosis of MYH9-RD: Predicting pathogenic variants.

Bury L, Megy K, Stephens JC, Grassi L, Greene D, Gleadall N, Althaus K, Allsup D, Bariana TK, Bonduel M, Butta NV, Collins P, Curry N, Deevi SVV, Downes K, Duarte D, Elliott K, Falcinelli E, Furie B, Keeling D, Lambert MP, Linger R, Mangles S, Mapeta R, Millar CM, Penkett C, Perry DJ, Stirrups KE, Turro E, Westbury SK, Wu J, BioResource N, Gomez K, Freson K, Ouwehand WH, Gresele P, Simeoni I.

Hum Mutat. 2019 Sep 28. doi: 10.1002/humu.23927. [Epub ahead of print]

PMID:
31562665
2.

Antithrombotic prophylaxis for surgery-associated venous thromboembolism risk in patients with inherited platelet disorders. The SPATA-DVT Study.

Paciullo F, Bury L, Noris P, Falcinelli E, Melazzini F, Orsini S, Zaninetti C, Abdul-Kadir R, Obeng-Tuudah D, Heller P, Glembotsky AC, Fabris F, Rivera J, Lozano ML, Butta N, Favier R, Cid AR, Fouassier M, Podda GM, Santoro C, Grandone E, Henskens Y, Nurden P, Zieger B, Cuker A, Devreese K, Tosetto A, De Candia E, Dupuis A, Miyazaki K, Othman M, Gresele P.

Haematologica. 2019 Sep 26. pii: haematol.2019.227876. doi: 10.3324/haematol.2019.227876. [Epub ahead of print]

3.

Inherited platelet disorders in women.

Gresele P, Falcinelli E, Bury L.

Thromb Res. 2019 Sep;181 Suppl 1:S54-S59. doi: 10.1016/S0049-3848(19)30368-8. Review.

PMID:
31477229
4.

Enhancing the antibacterial activity of polymyxins using a nonantibiotic drug.

Krishnamurthy M, Lemmon MM, Falcinelli EM, Sandy RA, Dootz JN, Mott TM, Rajamani S, Schaecher KE, Duplantier AJ, Panchal RG.

Infect Drug Resist. 2019 May 27;12:1393-1405. doi: 10.2147/IDR.S196874. eCollection 2019.

5.

Maraviroc Intensification Modulates Atherosclerotic Progression in HIV-Suppressed Patients at High Cardiovascular Risk. A Randomized, Crossover Pilot Study.

Francisci D, Pirro M, Schiaroli E, Mannarino MR, Cipriani S, Bianconi V, Alunno A, Bagaglia F, Bistoni O, Falcinelli E, Bury L, Gerli R, Mannarino E, De Caterina R, Baldelli F.

Open Forum Infect Dis. 2019 Mar 7;6(4):ofz112. doi: 10.1093/ofid/ofz112. eCollection 2019 Apr.

6.

Inhibition of platelet function after ocular administration of non-steroidal anti-inflammatory drugs.

Falcinelli E, Iannone A, Mezzasoma AM, Amato L, Fierro T, Guglielmini G, Cagini C, Gresele P.

Thromb Res. 2019 Mar;175:1-5. doi: 10.1016/j.thromres.2019.01.005. Epub 2019 Jan 11.

PMID:
30660018
7.

Platelet function assays in diagnosis: an update.

Gresele P, Bury L, Mezzasoma AM, Falcinelli E.

Expert Rev Hematol. 2019 Jan;12(1):29-46. doi: 10.1080/17474086.2019.1562333. Epub 2019 Jan 16.

PMID:
30571151
8.

Laboratory diagnosis of clinically relevant platelet function disorders.

Gresele P, Falcinelli E, Bury L.

Int J Lab Hematol. 2018 May;40 Suppl 1:34-45. doi: 10.1111/ijlh.12814. Review.

PMID:
29741257
9.

Effect of aspirin treatment on abacavir-associated platelet hyperreactivity in HIV-infected patients.

Falcinelli E, Francisci D, Schiaroli E, Minuz P, Orsini S, Malincarne L, Sebastiano M, Mezzasoma AM, Pasticci MB, Guglielmini G, Baldelli F, Gresele P.

Int J Cardiol. 2018 Jul 15;263:118-124. doi: 10.1016/j.ijcard.2018.04.052. Epub 2018 Apr 12.

PMID:
29685693
10.

A novel variant Glanzmann thrombasthenia due to co-inheritance of a loss- and a gain-of-function mutation of ITGB3: evidence of a dominant effect of gain-of-function mutations.

Bury L, Zetterberg E, Leinøe EB, Falcinelli E, Marturano A, Manni G, Nurden AT, Gresele P.

Haematologica. 2018 Jun;103(6):e259-e263. doi: 10.3324/haematol.2017.180927. Epub 2018 Feb 8. No abstract available.

11.

Neuromedin U potentiates ADP- and epinephrine-induced human platelet activation.

Grippi C, Izzi B, Gianfagna F, Noro F, Falcinelli E, Di Pardo A, Amico E, Donati MB, de Gaetano G, Iacoviello L, Hoylaerts MF, Cerletti C.

Thromb Res. 2017 Nov;159:100-108. doi: 10.1016/j.thromres.2017.09.027. Epub 2017 Sep 29.

PMID:
29078099
12.

Platelets Contribute to the Accumulation of Matrix Metalloproteinase Type 2 in Synovial Fluid in Osteoarthritis.

Alunno A, Falcinelli E, Luccioli F, Petito E, Bartoloni E, Momi S, Mirabelli G, Mancini GB, Gerli R, Gresele P.

Thromb Haemost. 2017 Nov;117(11):2116-2124. doi: 10.1160/TH17-06-0379. Epub 2017 Nov 30.

PMID:
28981555
13.

Increase of von Willebrand factor with aging in type 1 von Willebrand disease: fact or fiction?

Borghi M, Guglielmini G, Mezzasoma AM, Falcinelli E, Bury L, Malvestiti M, Gresele P.

Haematologica. 2017 Nov;102(11):e431-e433. doi: 10.3324/haematol.2017.168013. Epub 2017 Jul 27. No abstract available.

14.

Endothelial activation in patients with superficial vein thrombosis (SVT) of the lower limbs.

Falcinelli E, Cosmi B, Filippini M, Petito E, Legnani C, Cini M, Guglielmini G, Migliacci R, Palareti G, Gresele P.

Thromb Res. 2017 Sep;157:20-22. doi: 10.1016/j.thromres.2017.06.033. Epub 2017 Jun 27. No abstract available.

PMID:
28679113
15.

Platelet amyloid precursor protein is a modulator of venous thromboembolism in mice.

Canobbio I, Visconte C, Momi S, Guidetti GF, Zarà M, Canino J, Falcinelli E, Gresele P, Torti M.

Blood. 2017 Jul 27;130(4):527-536. doi: 10.1182/blood-2017-01-764910. Epub 2017 Jun 13.

PMID:
28611024
16.

Matrix Metalloproteinases and Platelet Function.

Gresele P, Falcinelli E, Sebastiano M, Momi S.

Prog Mol Biol Transl Sci. 2017;147:133-165. doi: 10.1016/bs.pmbts.2017.01.002. Epub 2017 Mar 21. Review.

PMID:
28413027
17.

Bleeding risk of surgery and its prevention in patients with inherited platelet disorders.

Orsini S, Noris P, Bury L, Heller PG, Santoro C, Kadir RA, Butta NC, Falcinelli E, Cid AR, Fabris F, Fouassier M, Miyazaki K, Lozano ML, Zúñiga P, Flaujac C, Podda GM, Bermejo N, Favier R, Henskens Y, De Maistre E, De Candia E, Mumford AD, Ozdemir GN, Eker I, Nurden P, Bayart S, Lambert MP, Bussel J, Zieger B, Tosetto A, Melazzini F, Glembotsky AC, Pecci A, Cattaneo M, Schlegel N, Gresele P; European Hematology Association - Scientific Working Group (EHA-SWG) on thrombocytopenias and platelet function disorders.

Haematologica. 2017 Jul;102(7):1192-1203. doi: 10.3324/haematol.2016.160754. Epub 2017 Apr 6.

18.

A novel mechanism regulating human platelet activation by MMP-2-mediated PAR1 biased signaling.

Sebastiano M, Momi S, Falcinelli E, Bury L, Hoylaerts MF, Gresele P.

Blood. 2017 Feb 16;129(7):883-895. doi: 10.1182/blood-2016-06-724245. Epub 2016 Dec 29.

PMID:
28034890
19.

Inherited platelet function disorders. Diagnostic approach and management.

Gresele P, Falcinelli E, Bury L.

Hamostaseologie. 2016 Nov 7;36(4):265-278. Epub 2016 Aug 3. Review.

PMID:
27484722
20.

Inherited Platelet Function Disorders: Algorithms for Phenotypic and Genetic Investigation.

Gresele P, Bury L, Falcinelli E.

Semin Thromb Hemost. 2016 Apr;42(3):292-305. doi: 10.1055/s-0035-1570078. Epub 2016 Mar 10. Review.

PMID:
26962877
21.

Matrix metalloproteinase-2 enhances platelet deposition on collagen under flow conditions.

Guglielmini G, Appolloni V, Momi S, De Groot PG, Battiston M, De Marco L, Falcinelli E, Gresele P.

Thromb Haemost. 2016 Jan;115(2):333-43. doi: 10.1160/TH15-04-0300. Epub 2015 Oct 29.

PMID:
26510894
22.

Cytoskeletal perturbation leads to platelet dysfunction and thrombocytopenia in variant forms of Glanzmann thrombasthenia.

Bury L, Falcinelli E, Chiasserini D, Springer TA, Italiano JE Jr, Gresele P.

Haematologica. 2016 Jan;101(1):46-56. doi: 10.3324/haematol.2015.130849. Epub 2015 Oct 9.

23.

Prevalence of hemostatic alterations in patients with recurrent spontaneous subconjunctival hemorrhage.

Fierro T, Bartolini A, Mezzasoma AM, Guglielmini G, Falcinelli E, Orsini S, Momi S, Cagini C, Gresele P.

Clin Chem Lab Med. 2016 Jan;54(1):97-103. doi: 10.1515/cclm-2015-0274.

PMID:
26087065
24.

Highly active antiretroviral therapy-related mechanisms of endothelial and platelet function alterations.

Gresele P, Falcinelli E, Momi S, Francisci D, Baldelli F.

Rev Cardiovasc Med. 2014;15 Suppl 1:S9-20. Review.

PMID:
24987863
25.

Diagnosis of suspected inherited platelet function disorders: results of a worldwide survey.

Gresele P, Harrison P, Bury L, Falcinelli E, Gachet C, Hayward CP, Kenny D, Mezzano D, Mumford AD, Nugent D, Nurden AT, Orsini S, Cattaneo M.

J Thromb Haemost. 2014 Sep;12(9):1562-9. doi: 10.1111/jth.12650. Epub 2014 Jul 25.

26.

Analysis of 339 pregnancies in 181 women with 13 different forms of inherited thrombocytopenia.

Noris P, Schlegel N, Klersy C, Heller PG, Civaschi E, Pujol-Moix N, Fabris F, Favier R, Gresele P, Latger-Cannard V, Cuker A, Nurden P, Greinacher A, Cattaneo M, De Candia E, Pecci A, Hurtaud-Roux MF, Glembotsky AC, Muñiz-Diaz E, Randi ML, Trillot N, Bury L, Lecompte T, Marconi C, Savoia A, Balduini CL, Bayart S, Bauters A, Benabdallah-Guedira S, Boehlen F, Borg JY, Bottega R, Bussel J, De Rocco D, de Maistre E, Faleschini M, Falcinelli E, Ferrari S, Ferster A, Fierro T, Fleury D, Fontana P, James C, Lanza F, Le Cam Duchez V, Loffredo G, Magini P, Martin-Coignard D, Menard F, Mercier S, Mezzasoma A, Minuz P, Nichele I, Notarangelo LD, Pippucci T, Podda GM, Pouymayou C, Rigouzzo A, Royer B, Sie P, Siguret V, Trichet C, Tucci A, Saposnik B, Veneri D; European Hematology Association – Scientific Working Group on Thrombocytopenias and Platelet Function Disorders.

Haematologica. 2014 Aug;99(8):1387-94. doi: 10.3324/haematol.2014.105924. Epub 2014 Apr 24.

27.

Potential anti-inflammatory effects of maraviroc in HIV-positive patients: a pilot study of inflammation, endothelial dysfunction, and coagulation markers.

Francisci D, Falcinelli E, Baroncelli S, Petito E, Cecchini E, Weimer LE, Floridia M, Gresele P, Baldelli F.

Scand J Infect Dis. 2014 Jun;46(6):466-70. doi: 10.3109/00365548.2014.898332. Epub 2014 Apr 16.

PMID:
24738757
28.

Stimulation of platelet nitric oxide production by nebivolol prevents thrombosis.

Momi S, Caracchini R, Falcinelli E, Evangelista S, Gresele P.

Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):820-9. doi: 10.1161/ATVBAHA.114.303290. Epub 2014 Feb 20.

PMID:
24558107
29.

Matrix metalloproteinase-2 of human carotid atherosclerotic plaques promotes platelet activation. Correlation with ischaemic events.

Lenti M, Falcinelli E, Pompili M, de Rango P, Conti V, Guglielmini G, Momi S, Corazzi T, Giordano G, Gresele P.

Thromb Haemost. 2014 Jun;111(6):1089-101. doi: 10.1160/TH13-07-0588. Epub 2014 Feb 6.

PMID:
24499865
30.

In vivo platelet activation and platelet hyperreactivity in abacavir-treated HIV-infected patients.

Falcinelli E, Francisci D, Belfiori B, Petito E, Guglielmini G, Malincarne L, Mezzasoma A, Sebastiano M, Conti V, Giannini S, Bonora S, Baldelli F, Gresele P.

Thromb Haemost. 2013 Aug;110(2):349-57. doi: 10.1160/TH12-07-0504. Epub 2013 May 23.

PMID:
23703656
31.

Platelet and endothelial activation in catastrophic and quiescent antiphospholipid syndrome.

Bontadi A, Ruffatti A, Falcinelli E, Giannini S, Marturano A, Tonello M, Hoxha A, Pengo V, Punzi L, Momi S, Gresele P.

Thromb Haemost. 2013 May;109(5):901-8. doi: 10.1160/TH12-03-0212. Epub 2013 Apr 4.

PMID:
23572134
32.

C-reactive protein induces expression of matrix metalloproteinase-9: a possible link between inflammation and plaque rupture.

Cimmino G, Ragni M, Cirillo P, Petrillo G, Loffredo F, Chiariello M, Gresele P, Falcinelli E, Golino P.

Int J Cardiol. 2013 Sep 30;168(2):981-6. doi: 10.1016/j.ijcard.2012.10.040. Epub 2012 Nov 14.

PMID:
23157807
33.

Higher levels of plasma matrix metalloproteinase-2 are associated with a significantly increased risk of arterial thrombosis in patients with the antiphospholipid syndrome.

Falcinelli E, Pompili M, Pengo V, Appolloni V, Guglielmini G, Gresele P.

Int J Cardiol. 2012 Oct 4;160(2):149-51. doi: 10.1016/j.ijcard.2012.05.074. Epub 2012 Jun 19. No abstract available.

PMID:
22721641
34.

In vitro effect of anti-β₂ glycoprotein I antibodies on P-selectin expression, a marker of platelet activation.

Bontadi A, Ruffatti A, Giannini S, Falcinelli E, Tonello M, Hoxha A, Gresele P, Punzi L.

Reumatismo. 2012 Mar 19;64(1):35-9. doi: 10.4081/reumatismo.2012.35.

PMID:
22472781
35.

Nitric oxide enhances the anti-inflammatory and anti-atherogenic activity of atorvastatin in a mouse model of accelerated atherosclerosis.

Momi S, Monopoli A, Alberti PF, Falcinelli E, Corazzi T, Conti V, Miglietta D, Ongini E, Minuz P, Gresele P.

Cardiovasc Res. 2012 Jun 1;94(3):428-38. doi: 10.1093/cvr/cvs100. Epub 2012 Feb 23.

PMID:
22362817
36.

Endothelial and platelet function alterations in HIV-infected patients.

Gresele P, Falcinelli E, Sebastiano M, Baldelli F.

Thromb Res. 2012 Mar;129(3):301-8. doi: 10.1016/j.thromres.2011.11.022. Epub 2011 Dec 20.

PMID:
22192157
37.

Contribution of matrix metalloproteinase 2 to joint destruction in group B Streptococcus-induced murine arthritis.

Puliti M, Momi S, Falcinelli E, Gresele P, Bistoni F, Tissi L.

Arthritis Rheum. 2012 Apr;64(4):1089-97. doi: 10.1002/art.33450. Epub 2011 Oct 31.

38.

Impact of tenofovir versus abacavir on HIV-related endothelial dysfunction.

Francisci D, Falcinelli E, Belfiori B, Petito E, Fierro T, Baldelli F, Gresele P.

AIDS Patient Care STDS. 2011 Oct;25(10):567-9. doi: 10.1089/apc.2011.0184. Epub 2011 Aug 18. No abstract available.

PMID:
21851265
39.

Anti-platelet therapy: phosphodiesterase inhibitors.

Gresele P, Momi S, Falcinelli E.

Br J Clin Pharmacol. 2011 Oct;72(4):634-46. doi: 10.1111/j.1365-2125.2011.04034.x. Review.

40.

Interaction with damaged vessel wall in vivo in humans induces platelets to express CD40L resulting in endothelial activation with no effect of aspirin intake.

Giannini S, Falcinelli E, Bury L, Guglielmini G, Rossi R, Momi S, Gresele P.

Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2072-9. doi: 10.1152/ajpheart.00467.2010. Epub 2011 Mar 4.

41.

Platelets release matrix metalloproteinase-2 in the coronary circulation of patients with acute coronary syndromes: possible role in sustained platelet activation.

Gresele P, Falcinelli E, Loffredo F, Cimmino G, Corazzi T, Forte L, Guglielmini G, Momi S, Golino P.

Eur Heart J. 2011 Feb;32(3):316-25. doi: 10.1093/eurheartj/ehq390. Epub 2010 Oct 28.

PMID:
21036774
42.

Loss of matrix metalloproteinase 2 in platelets reduces arterial thrombosis in vivo.

Momi S, Falcinelli E, Giannini S, Ruggeri L, Cecchetti L, Corazzi T, Libert C, Gresele P.

J Exp Med. 2009 Oct 26;206(11):2365-79. doi: 10.1084/jem.20090687. Epub 2009 Oct 5.

43.

Matrix metalloproteinases and peripheral arterial disease.

Busti C, Falcinelli E, Momi S, Gresele P.

Intern Emerg Med. 2010 Feb;5(1):13-25. doi: 10.1007/s11739-009-0283-y. Epub 2009 Jul 21. Review. Erratum in: Intern Emerg Med. 2010 Feb;5(1):89.

PMID:
19626421
44.

Dominant inheritance of a novel integrin beta3 mutation associated with a hereditary macrothrombocytopenia and platelet dysfunction in two Italian families.

Gresele P, Falcinelli E, Giannini S, D'Adamo P, D'Eustacchio A, Corazzi T, Mezzasoma AM, Di Bari F, Guglielmini G, Cecchetti L, Noris P, Balduini CL, Savoia A.

Haematologica. 2009 May;94(5):663-9. doi: 10.3324/haematol.2008.002246. Epub 2009 Mar 31.

45.

Plasma levels of beta(2)-microglobulin, a biomarker of peripheral arterial disease, are not affected by maximal leg exercise in patients with intermittent claudication.

Busti C, Migliacci R, Falcinelli E, Gresele P.

Atherosclerosis. 2009 Mar;203(1):38-40. doi: 10.1016/j.atherosclerosis.2008.06.023. Epub 2008 Jul 1. No abstract available.

PMID:
18674763
46.

Potentiation and priming of platelet activation: a potential target for antiplatelet therapy.

Gresele P, Falcinelli E, Momi S.

Trends Pharmacol Sci. 2008 Jul;29(7):352-60. doi: 10.1016/j.tips.2008.05.002. Epub 2008 Jun 6. Review.

PMID:
18539343
47.

A new case of acquired Glanzmann's thrombasthenia: diagnostic value of flow cytometry.

Giannini S, Mezzasoma AM, Guglielmini G, Rossi R, Falcinelli E, Gresele P.

Cytometry B Clin Cytom. 2008 May;74(3):194-9. doi: 10.1002/cyto.b.20396.

48.

Platelets release active matrix metalloproteinase-2 in vivo in humans at a site of vascular injury: lack of inhibition by aspirin.

Falcinelli E, Giannini S, Boschetti E, Gresele P.

Br J Haematol. 2007 Jul;138(2):221-30.

PMID:
17593030
49.

Endothelial dysfunction in patients with spontaneous venous thromboembolism.

Migliacci R, Becattini C, Pesavento R, Davi G, Vedovati MC, Guglielmini G, Falcinelli E, Ciabattoni G, Dalla Valle F, Prandoni P, Agnelli G, Gresele P.

Haematologica. 2007 Jun;92(6):812-8.

50.

Intraplatelet signaling mechanisms of the priming effect of matrix metalloproteinase-2 on platelet aggregation.

Falcinelli E, Guglielmini G, Torti M, Gresele P.

J Thromb Haemost. 2005 Nov;3(11):2526-35.

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