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Items: 1 to 50 of 107

1.

Vision of a near future: Bridging the human health-environment divide. Toward an integrated strategy to understand mechanisms across species for chemical safety assessment.

Rivetti C, Allen TEH, Brown JB, Butler E, Carmichael PL, Colbourne JK, Dent M, Falciani F, Gunnarsson L, Gutsell S, Harrill JA, Hodges G, Jennings P, Judson R, Kienzler A, Margiotta-Casaluci L, Muller I, Owen SF, Rendal C, Russell PJ, Scott S, Sewell F, Shah I, Sorrel I, Viant MR, Westmoreland C, White A, Campos B.

Toxicol In Vitro. 2020 Feb;62:104692. doi: 10.1016/j.tiv.2019.104692. Epub 2019 Oct 25.

PMID:
31669395
2.

Computationally Predicted Gene Regulatory Networks in Molluscan Biomineralisation Identify Extracellular Matrix Production and Ion Transportation Pathways.

Sleight VA, Antczak P, Falciani F, Clark MS.

Bioinformatics. 2019 Oct 16. pii: btz754. doi: 10.1093/bioinformatics/btz754. [Epub ahead of print]

PMID:
31617561
3.

From near-zero to zero fluoroscopy catheter ablation procedures.

Santoro A, Di Clemente F, Baiocchi C, Zacà V, Bianchi C, Bellini C, Falciani F, Valente S, Gaspardone A, Lamberti F.

J Cardiovasc Electrophysiol. 2019 Nov;30(11):2397-2404. doi: 10.1111/jce.14121. Epub 2019 Sep 4.

PMID:
31424119
4.

Deciphering the complex role of thrombospondin-1 in glioblastoma development.

Daubon T, Léon C, Clarke K, Andrique L, Salabert L, Darbo E, Pineau R, Guérit S, Maitre M, Dedieu S, Jeanne A, Bailly S, Feige JJ, Miletic H, Rossi M, Bello L, Falciani F, Bjerkvig R, Bikfalvi A.

Nat Commun. 2019 Mar 8;10(1):1146. doi: 10.1038/s41467-019-08480-y.

5.

Systems biology reveals how altered TGFβ signalling with age reduces protection against pro-inflammatory stimuli.

Hodgson D, Rowan AD, Falciani F, Proctor CJ.

PLoS Comput Biol. 2019 Jan 24;15(1):e1006685. doi: 10.1371/journal.pcbi.1006685. eCollection 2019 Jan.

6.

Chemical hazard prediction and hypothesis testing using quantitative adverse outcome pathways.

Perkins EJ, Gayen K, Shoemaker JE, Antczak P, Burgoon L, Falciani F, Gutsell S, Hodges G, Kienzler A, Knapen D, McBride M, Willett C, Doyle FJ, Garcia-Reyero N.

ALTEX. 2019;36(1):91-102. doi: 10.14573/altex.1808241. Epub 2018 Oct 16.

7.

Comparative toxicity of three phenolic compounds on the embryo of fathead minnow, Pimephales promelas.

Li E, Bolser DG, Kroll KJ, Brockmeier EK, Falciani F, Denslow ND.

Aquat Toxicol. 2018 Aug;201:66-72. doi: 10.1016/j.aquatox.2018.05.024. Epub 2018 May 29.

PMID:
29879596
8.

In Silico Computational Transcriptomics Reveals Novel Endocrine Disruptors in Largemouth Bass ( Micropterus salmoides).

Basili D, Zhang JL, Herbert J, Kroll K, Denslow ND, Martyniuk CJ, Falciani F, Antczak P.

Environ Sci Technol. 2018 Jul 3;52(13):7553-7565. doi: 10.1021/acs.est.8b02805. Epub 2018 Jun 15.

9.

Impact of Pedal Arch Patency on Tissue Loss and Time to Healing in Diabetic Patients with Foot Wounds Undergoing Infrainguinal Endovascular Revascularization.

Troisi N, Turini F, Chisci E, Ercolini L, Frosini P, Lombardi R, Falciani F, Baggiore C, Anichini R, Michelagnoli S.

Korean J Radiol. 2018 Jan-Feb;19(1):47-53. doi: 10.3348/kjr.2018.19.1.47. Epub 2018 Jan 2.

10.

The Role of Eif6 in Skeletal Muscle Homeostasis Revealed by Endurance Training Co-expression Networks.

Clarke K, Ricciardi S, Pearson T, Bharudin I, Davidsen PK, Bonomo M, Brina D, Scagliola A, Simpson DM, Beynon RJ, Khanim F, Ankers J, Sarzynski MA, Ghosh S, Pisconti A, Rozman J, Hrabe de Angelis M, Bunce C, Stewart C, Egginton S, Caddick M, Jackson M, Bouchard C, Biffo S, Falciani F.

Cell Rep. 2017 Nov 7;21(6):1507-1520. doi: 10.1016/j.celrep.2017.10.040.

11.

Kinome-wide transcriptional profiling of uveal melanoma reveals new vulnerabilities to targeted therapeutics.

Bailey FP, Clarke K, Kalirai H, Kenyani J, Shahidipour H, Falciani F, Coulson JM, Sacco JJ, Coupland SE, Eyers PA.

Pigment Cell Melanoma Res. 2018 Mar;31(2):253-266. doi: 10.1111/pcmr.12650. Epub 2017 Oct 15. Review.

PMID:
28972303
12.

NR4A orphan nuclear receptor family members, NR4A2 and NR4A3, regulate neutrophil number and survival.

Prince LR, Prosseda SD, Higgins K, Carlring J, Prestwich EC, Ogryzko NV, Rahman A, Basran A, Falciani F, Taylor P, Renshaw SA, Whyte MKB, Sabroe I.

Blood. 2017 Aug 24;130(8):1014-1025. doi: 10.1182/blood-2017-03-770164. Epub 2017 Jun 21.

13.

Pedal arch patency and not direct-angiosome revascularization predicts outcomes of endovascular interventions in diabetic patients with critical limb ischemia.

Troisi N, Turini F, Chisci E, Ercolini L, Frosini P, Lombardi R, Falciani F, Baggiore C, Anichini R, Michelagnoli S.

Int Angiol. 2017 Oct;36(5):438-444. doi: 10.23736/S0392-9590.17.03809-3. Epub 2017 May 24.

14.

The Role of Omics in the Application of Adverse Outcome Pathways for Chemical Risk Assessment.

Brockmeier EK, Hodges G, Hutchinson TH, Butler E, Hecker M, Tollefsen KE, Garcia-Reyero N, Kille P, Becker D, Chipman K, Colbourne J, Collette TW, Cossins A, Cronin M, Graystock P, Gutsell S, Knapen D, Katsiadaki I, Lange A, Marshall S, Owen SF, Perkins EJ, Plaistow S, Schroeder A, Taylor D, Viant M, Ankley G, Falciani F.

Toxicol Sci. 2017 Aug 1;158(2):252-262. doi: 10.1093/toxsci/kfx097. Review.

15.

How consistent are we? Interlaboratory comparison study in fathead minnows using the model estrogen 17α-ethinylestradiol to develop recommendations for environmental transcriptomics.

Feswick A, Isaacs M, Biales A, Flick RW, Bencic DC, Wang RL, Vulpe C, Brown-Augustine M, Loguinov A, Falciani F, Antczak P, Herbert J, Brown L, Denslow ND, Kroll KJ, Lavelle C, Dang V, Escalon L, Garcia-Reyero N, Martyniuk CJ, Munkittrick KR.

Environ Toxicol Chem. 2017 Oct;36(10):2614-2623. doi: 10.1002/etc.3799. Epub 2017 Apr 19.

16.

Transcriptional mechanism of vascular endothelial growth factor-induced expression of protein kinase CβII in chronic lymphocytic leukaemia cells.

Al-Sanabra O, Duckworth AD, Glenn MA, Brown BR, Angelillo P, Lee K, Herbert J, Falciani F, Kalakonda N, Slupsky JR.

Sci Rep. 2017 Feb 24;7:43228. doi: 10.1038/srep43228.

17.

Transcriptional responses to hyperplastic MRL signalling in Drosophila.

Jonchère V, Alqadri N, Herbert J, Dodgson L, Mason D, Messina G, Falciani F, Bennett D.

Open Biol. 2017 Feb;7(2). pii: 160306. doi: 10.1098/rsob.160306.

18.

Efficacy, safety and feasibility of intravenous iloprost in the domiciliary treatment of patients with ischemic disease of the lower limbs.

Polignano R, Baggiore C, Falciani F, Restelli U, Troisi N, Michelagnoli S, Panigada G, Tatini S, Farina A, Landini G.

Eur Rev Med Pharmacol Sci. 2016 Sep;20(17):3720-6.

19.

A Network Biology Approach Identifies Molecular Cross-Talk between Normal Prostate Epithelial and Prostate Carcinoma Cells.

Trevino V, Cassese A, Nagy Z, Zhuang X, Herbert J, Antczak P, Clarke K, Davies N, Rahman A, Campbell MJ, Guindani M, Bicknell R, Vannucci M, Falciani F.

PLoS Comput Biol. 2016 Apr 28;12(4):e1004884. doi: 10.1371/journal.pcbi.1004884. eCollection 2016 Apr. Erratum in: PLoS Comput Biol. 2016 Oct 17;12 (10 ):e1005172. Antzack P [corrected to Antczak P].

20.

Effect of a wound cleansing solution on wound bed preparation and inflammation in chronic wounds: a single-blind RCT.

Bellingeri A, Falciani F, Traspedini P, Moscatelli A, Russo A, Tino G, Chiari P, Peghetti A.

J Wound Care. 2016 Mar;25(3):160, 162-6, 168. doi: 10.12968/jowc.2016.25.3.160.

PMID:
26947697
21.

ChainRank, a chain prioritisation method for contextualisation of biological networks.

Tényi Á, de Atauri P, Gomez-Cabrero D, Cano I, Clarke K, Falciani F, Cascante M, Roca J, Maier D.

BMC Bioinformatics. 2016 Jan 5;17:17. doi: 10.1186/s12859-015-0864-x.

22.

Multilevel functional genomics data integration as a tool for understanding physiology: a network biology perspective.

Davidsen PK, Turan N, Egginton S, Falciani F.

J Appl Physiol (1985). 2016 Feb 1;120(3):297-309. doi: 10.1152/japplphysiol.01110.2014. Epub 2015 Nov 5. Review.

23.

Adverse Outcome Pathways for Regulatory Applications: Examination of Four Case Studies With Different Degrees of Completeness and Scientific Confidence.

Perkins EJ, Antczak P, Burgoon L, Falciani F, Garcia-Reyero N, Gutsell S, Hodges G, Kienzler A, Knapen D, McBride M, Willett C.

Toxicol Sci. 2015 Nov;148(1):14-25. doi: 10.1093/toxsci/kfv181. Review.

PMID:
26500288
24.

Genomic and transcriptomic predictors of triglyceride response to regular exercise.

Sarzynski MA, Davidsen PK, Sung YJ, Hesselink MK, Schrauwen P, Rice TK, Rao DC, Falciani F, Bouchard C.

Br J Sports Med. 2015 Dec;49(23):1524-31. doi: 10.1136/bjsports-2015-095179. Epub 2015 Oct 21.

25.

Eukaryotic translation initiation factor 6 is a novel regulator of reactive oxygen species-dependent megakaryocyte maturation.

Ricciardi S, Miluzio A, Brina D, Clarke K, Bonomo M, Aiolfi R, Guidotti LG, Falciani F, Biffo S.

J Thromb Haemost. 2015 Nov;13(11):2108-18. doi: 10.1111/jth.13150. Epub 2015 Oct 23.

26.

eIF6 coordinates insulin sensitivity and lipid metabolism by coupling translation to transcription.

Brina D, Miluzio A, Ricciardi S, Clarke K, Davidsen PK, Viero G, Tebaldi T, Offenhäuser N, Rozman J, Rathkolb B, Neschen S, Klingenspor M, Wolf E, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Quattrone A, Falciani F, Biffo S.

Nat Commun. 2015 Sep 18;6:8261. doi: 10.1038/ncomms9261.

27.

Pressure Ulcers in Older Adults: A Prevalence Study.

Rasero L, Simonetti M, Falciani F, Fabbri C, Collini F, Dal Molin A.

Adv Skin Wound Care. 2015 Oct;28(10):461-4. doi: 10.1097/01.ASW.0000470371.77571.5d.

PMID:
26375949
28.

Systems Biology Approach Reveals a Calcium-Dependent Mechanism for Basal Toxicity in Daphnia magna.

Antczak P, White TA, Giri A, Michelangeli F, Viant MR, Cronin MT, Vulpe C, Falciani F.

Environ Sci Technol. 2015 Sep 15;49(18):11132-40. doi: 10.1021/acs.est.5b02707. Epub 2015 Aug 24.

PMID:
26244374
29.

Inference of Low and High-Grade Glioma Gene Regulatory Networks Delineates the Role of Rnd3 in Establishing Multiple Hallmarks of Cancer.

Clarke K, Daubon T, Turan N, Soulet F, Mohd Zahari M, Ryan KR, Durant S, He S, Herbert J, Ankers J, Heath JK, Bjerkvig R, Bicknell R, Hotchin NA, Bikfalvi A, Falciani F.

PLoS Genet. 2015 Jul 1;11(7):e1005325. doi: 10.1371/journal.pgen.1005325. eCollection 2015 Jul.

30.

Gene transcription, metabolite and lipid profiling in eco-indicator daphnia magna indicate diverse mechanisms of toxicity by legacy and emerging flame-retardants.

Scanlan LD, Loguinov AV, Teng Q, Antczak P, Dailey KP, Nowinski DT, Kornbluh J, Lin XX, Lachenauer E, Arai A, Douglas NK, Falciani F, Stapleton HM, Vulpe CD.

Environ Sci Technol. 2015 Jun 16;49(12):7400-10. doi: 10.1021/acs.est.5b00977. Epub 2015 Jun 1.

31.

Stromal transcriptional profiles reveal hierarchies of anatomical site, serum response and disease and identify disease specific pathways.

Filer A, Antczak P, Parsonage GN, Legault HM, O'Toole M, Pearson MJ, Thomas AM, Scheel-Toellner D, Raza K, Buckley CD, Falciani F.

PLoS One. 2015 Mar 25;10(3):e0120917. doi: 10.1371/journal.pone.0120917. eCollection 2015.

32.

A Bayesian model for the identification of differentially expressed genes in Daphnia magna exposed to munition pollutants.

Cassese A, Guindani M, Antczak P, Falciani F, Vannucci M.

Biometrics. 2015 Sep;71(3):803-11. doi: 10.1111/biom.12303. Epub 2015 Mar 13.

33.

Future water quality monitoring--adapting tools to deal with mixtures of pollutants in water resource management.

Altenburger R, Ait-Aissa S, Antczak P, Backhaus T, Barceló D, Seiler TB, Brion F, Busch W, Chipman K, de Alda ML, de Aragão Umbuzeiro G, Escher BI, Falciani F, Faust M, Focks A, Hilscherova K, Hollender J, Hollert H, Jäger F, Jahnke A, Kortenkamp A, Krauss M, Lemkine GF, Munthe J, Neumann S, Schymanski EL, Scrimshaw M, Segner H, Slobodnik J, Smedes F, Kughathas S, Teodorovic I, Tindall AJ, Tollefsen KE, Walz KH, Williams TD, Van den Brink PJ, van Gils J, Vrana B, Zhang X, Brack W.

Sci Total Environ. 2015 Apr 15;512-513:540-551. doi: 10.1016/j.scitotenv.2014.12.057. Epub 2015 Jan 31.

PMID:
25644849
34.

Chronic Obstructive Pulmonary Disease heterogeneity: challenges for health risk assessment, stratification and management.

Roca J, Vargas C, Cano I, Selivanov V, Barreiro E, Maier D, Falciani F, Wagner P, Cascante M, Garcia-Aymerich J, Kalko S, De Mas I, Tegnér J, Escarrabill J, Agustí A, Gomez-Cabrero D; Synergy-COPD consortium.

J Transl Med. 2014 Nov 28;12 Suppl 2:S3. doi: 10.1186/1479-5876-12-S2-S3. Epub 2014 Nov 28. Review.

35.

The COPD Knowledge Base: enabling data analysis and computational simulation in translational COPD research.

Cano I, Tényi Á, Schueller C, Wolff M, Huertas Migueláñez MM, Gomez-Cabrero D, Antczak P, Roca J, Cascante M, Falciani F, Maier D.

J Transl Med. 2014 Nov 28;12 Suppl 2:S6. doi: 10.1186/1479-5876-12-S2-S6. Epub 2014 Nov 28.

36.

Systems Medicine: from molecular features and models to the clinic in COPD.

Gomez-Cabrero D, Menche J, Cano I, Abugessaisa I, Huertas-Migueláñez M, Tenyi A, Marin de Mas I, Kiani NA, Marabita F, Falciani F, Burrowes K, Maier D, Wagner P, Selivanov V, Cascante M, Roca J, Barabási AL, Tegnér J.

J Transl Med. 2014 Nov 28;12 Suppl 2:S4. doi: 10.1186/1479-5876-12-S2-S4. Epub 2014 Nov 28.

37.

A systems biology approach reveals a link between systemic cytokines and skeletal muscle energy metabolism in a rodent smoking model and human COPD.

Davidsen PK, Herbert JM, Antczak P, Clarke K, Ferrer E, Peinado VI, Gonzalez C, Roca J, Egginton S, Barberá JA, Falciani F.

Genome Med. 2014 Aug 9;6(8):59. doi: 10.1186/s13073-014-0059-5. eCollection 2014.

38.

The SOLUTIONS project: challenges and responses for present and future emerging pollutants in land and water resources management.

Brack W, Altenburger R, Schüürmann G, Krauss M, López Herráez D, van Gils J, Slobodnik J, Munthe J, Gawlik BM, van Wezel A, Schriks M, Hollender J, Tollefsen KE, Mekenyan O, Dimitrov S, Bunke D, Cousins I, Posthuma L, van den Brink PJ, López de Alda M, Barceló D, Faust M, Kortenkamp A, Scrimshaw M, Ignatova S, Engelen G, Massmann G, Lemkine G, Teodorovic I, Walz KH, Dulio V, Jonker MT, Jäger F, Chipman K, Falciani F, Liska I, Rooke D, Zhang X, Hollert H, Vrana B, Hilscherova K, Kramer K, Neumann S, Hammerbacher R, Backhaus T, Mack J, Segner H, Escher B, de Aragão Umbuzeiro G.

Sci Total Environ. 2015 Jan 15;503-504:22-31. doi: 10.1016/j.scitotenv.2014.05.143. Epub 2014 Jun 18.

PMID:
24951181
39.

A HIERARCHICAL BAYESIAN MODEL FOR INFERENCE OF COPY NUMBER VARIANTS AND THEIR ASSOCIATION TO GENE EXPRESSION.

Cassese A, Guindani M, Tadesse MG, Falciani F, Vannucci M.

Ann Appl Stat. 2014 Mar 1;8(1):148-175.

40.

Silver nanowire exposure results in internalization and toxicity to Daphnia magna.

Scanlan LD, Reed RB, Loguinov AV, Antczak P, Tagmount A, Aloni S, Nowinski DT, Luong P, Tran C, Karunaratne N, Pham D, Lin XX, Falciani F, Higgins CP, Ranville JF, Vulpe CD, Gilbert B.

ACS Nano. 2013 Dec 23;7(12):10681-94. doi: 10.1021/nn4034103. Epub 2013 Dec 5.

41.

Molecular toxicity identification evaluation (mTIE) approach predicts chemical exposure in Daphnia magna.

Antczak P, Jo HJ, Woo S, Scanlan L, Poynton H, Loguinov A, Chan S, Falciani F, Vulpe C.

Environ Sci Technol. 2013 Oct 15;47(20):11747-56. doi: 10.1021/es402819c. Epub 2013 Oct 7.

PMID:
23875995
42.

Gene expression networks underlying ovarian development in wild largemouth bass (Micropterus salmoides).

Martyniuk CJ, Prucha MS, Doperalski NJ, Antczak P, Kroll KJ, Falciani F, Barber DS, Denslow ND.

PLoS One. 2013;8(3):e59093. doi: 10.1371/journal.pone.0059093. Epub 2013 Mar 20.

43.

Germinal center B cells govern their own fate via antibody feedback.

Zhang Y, Meyer-Hermann M, George LA, Figge MT, Khan M, Goodall M, Young SP, Reynolds A, Falciani F, Waisman A, Notley CA, Ehrenstein MR, Kosco-Vilbois M, Toellner KM.

J Exp Med. 2013 Mar 11;210(3):457-64. doi: 10.1084/jem.20120150. Epub 2013 Feb 18.

44.

The experimental renal cell carcinoma model in the chick embryo.

Fergelot P, Bernhard JC, Soulet F, Kilarski WW, Léon C, Courtois N, Deminière C, Herbert JM, Antczak P, Falciani F, Rioux-Leclercq N, Patard JJ, Ferrière JM, Ravaud A, Hagedorn M, Bikfalvi A.

Angiogenesis. 2013 Jan;16(1):181-94. doi: 10.1007/s10456-012-9311-z. Epub 2012 Oct 18.

PMID:
23076651
45.

COMPADRE: an R and web resource for pathway activity analysis by component decompositions.

Ramos-Rodriguez RR, Cuevas-Diaz-Duran R, Falciani F, Tamez-Peña JG, Trevino V.

Bioinformatics. 2012 Oct 15;28(20):2701-2. doi: 10.1093/bioinformatics/bts513. Epub 2012 Aug 24.

PMID:
22923303
46.

Identification and pathway mapping of furan target proteins reveal mitochondrial energy production and redox regulation as critical targets of furan toxicity.

Moro S, Chipman JK, Antczak P, Turan N, Dekant W, Falciani F, Mally A.

Toxicol Sci. 2012 Apr;126(2):336-52. doi: 10.1093/toxsci/kfs005. Epub 2012 Jan 12.

PMID:
22240984
47.

Relative overexpression of X-linked genes in mouse embryonic stem cells is consistent with Ohno's hypothesis.

Lin H, Halsall JA, Antczak P, O'Neill LP, Falciani F, Turner BM.

Nat Genet. 2011 Nov 28;43(12):1169-70; author reply 1171-2. doi: 10.1038/ng.992. No abstract available.

PMID:
22120049
48.

Muscle and blood redox status after exercise training in severe COPD patients.

Rodriguez DA, Kalko S, Puig-Vilanova E, Perez-Olabarría M, Falciani F, Gea J, Cascante M, Barreiro E, Roca J.

Free Radic Biol Med. 2012 Jan 1;52(1):88-94. doi: 10.1016/j.freeradbiomed.2011.09.022. Epub 2011 Oct 4.

PMID:
22064359
49.

A systems biology approach identifies molecular networks defining skeletal muscle abnormalities in chronic obstructive pulmonary disease.

Turan N, Kalko S, Stincone A, Clarke K, Sabah A, Howlett K, Curnow SJ, Rodriguez DA, Cascante M, O'Neill L, Egginton S, Roca J, Falciani F.

PLoS Comput Biol. 2011 Sep;7(9):e1002129. doi: 10.1371/journal.pcbi.1002129. Epub 2011 Sep 1.

50.

Towards a system level understanding of non-model organisms sampled from the environment: a network biology approach.

Williams TD, Turan N, Diab AM, Wu H, Mackenzie C, Bartie KL, Hrydziuszko O, Lyons BP, Stentiford GD, Herbert JM, Abraham JK, Katsiadaki I, Leaver MJ, Taggart JB, George SG, Viant MR, Chipman KJ, Falciani F.

PLoS Comput Biol. 2011 Aug;7(8):e1002126. doi: 10.1371/journal.pcbi.1002126. Epub 2011 Aug 25.

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