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Items: 28

1.

5-HT3 Receptor Antagonists in Neurologic and Neuropsychiatric Disorders: The Iceberg Still Lies beneath the Surface.

Fakhfouri G, Rahimian R, Dyhrfjeld-Johnsen J, Zirak MR, Beaulieu JM.

Pharmacol Rev. 2019 Jul;71(3):383-412. doi: 10.1124/pr.118.015487. Review.

PMID:
31243157
2.

Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity.

Travelli C, Aprile S, Rahimian R, Grolla AA, Rogati F, Bertolotti M, Malagnino F, di Paola R, Impellizzeri D, Fusco R, Mercalli V, Massarotti A, Stortini G, Terrazzino S, Del Grosso E, Fakhfouri G, Troiani MP, Alisi MA, Grosa G, Sorba G, Canonico PL, Orsomando G, Cuzzocrea S, Genazzani AA, Galli U, Tron GC.

J Med Chem. 2017 Mar 9;60(5):1768-1792. doi: 10.1021/acs.jmedchem.6b01392. Epub 2017 Feb 22.

PMID:
28165742
3.

Oxytocin is involved in the proconvulsant effects of Sildenafil: Possible role of CREB.

Khoshneviszadeh M, Rahimian R, Fakhfouri G, Payandemehr B, Khodagholi F, Ejtemaei Mehr S, Dehpour AR.

Toxicol Lett. 2016 Aug 10;256:44-52. doi: 10.1016/j.toxlet.2016.05.018. Epub 2016 May 21.

PMID:
27220266
4.

Research update for articles published in EJCI in 2013.

Abbate R, Al-Daghri NM, Andreozzi P, Borregaard N, Can G, Caridi G, Carstensen-Kirberg M, Cioni G, Conte E, Cuomo R, Denis MA, Fakhfouri G, Fakhfouri G, Fiasse R, Glenthøj A, Goliasc G, Gremmel T, Herder C, Iemmolo M, Jing ZC, Krause R, Marrone O, Miazgowski B, Miazgowski T, Minchiotti L, Mousavizadeh K, Ndrepepa G, Niessner A, Ogayar Luque C, Onat A, Papassotiriou I, Ruiz Ortiz M, Sabico S, Schooling CM, Sakka SD, Sołtysiak P, Visseren FL, Wagner J, Wang XJ, Westerink J.

Eur J Clin Invest. 2015 Oct;45(10):1005-16. doi: 10.1111/eci.12512. No abstract available. Erratum in: Eur J Clin Invest. 2016 Apr;46(4):375.

PMID:
26394055
5.

Beyond the 5-HT3 receptors: A role for α7nACh receptors in neuroprotective aspects of tropisetron.

Khalifeh S, Fakhfouri G, Mehr SE, Mousavizadeh K, Dehpour AR, Khodagholi F, Kazmi S, Rahimian R.

Hum Exp Toxicol. 2015 Sep;34(9):922-31. doi: 10.1177/0960327114562034.

PMID:
26286524
6.

Behavioral despair associated with a mouse model of Crohn's disease: Role of nitric oxide pathway.

Heydarpour P, Rahimian R, Fakhfouri G, Khoshkish S, Fakhraei N, Salehi-Sadaghiani M, Wang H, Abbasi A, Dehpour AR, Ghia JE.

Prog Neuropsychopharmacol Biol Psychiatry. 2016 Jan 4;64:131-41. doi: 10.1016/j.pnpbp.2015.08.004. Epub 2015 Aug 9.

PMID:
26268932
7.

From Chemotherapy-Induced Emesis to Neuroprotection: Therapeutic Opportunities for 5-HT3 Receptor Antagonists.

Fakhfouri G, Mousavizadeh K, Mehr SE, Dehpour AR, Zirak MR, Ghia JE, Rahimian R.

Mol Neurobiol. 2015 Dec;52(3):1670-1679. doi: 10.1007/s12035-014-8957-5. Epub 2014 Nov 7. Review.

PMID:
25377794
8.

The role of serotonin in memory: interactions with neurotransmitters and downstream signaling.

Seyedabadi M, Fakhfouri G, Ramezani V, Mehr SE, Rahimian R.

Exp Brain Res. 2014 Mar;232(3):723-38. doi: 10.1007/s00221-013-3818-4. Epub 2014 Jan 16. Review.

PMID:
24430027
9.

5-HT3 receptor antagonists: new promising therapeutic agents in diabetes and its complications.

Rahimian R, Ejtemaei Mehr S, Fakhfouri G, Dehpour AR.

Acta Med Iran. 2013;51(10):736. No abstract available.

PMID:
24338152
10.

Tropisetron attenuates amyloid-beta-induced inflammatory and apoptotic responses in rats.

Rahimian R, Fakhfouri G, Ejtemaei Mehr S, Ghia JE, Genazzani AA, Payandemehr B, Dehpour AR, Mousavizadeh K, Lim D.

Eur J Clin Invest. 2013 Oct;43(10):1039-51. doi: 10.1111/eci.12141. Epub 2013 Aug 13.

PMID:
23937291
11.

Medicinal chemistry of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors.

Galli U, Travelli C, Massarotti A, Fakhfouri G, Rahimian R, Tron GC, Genazzani AA.

J Med Chem. 2013 Aug 22;56(16):6279-96. doi: 10.1021/jm4001049. Epub 2013 May 31. Review.

PMID:
23679915
12.

Estradiol reduces depressive-like behavior through inhibiting nitric oxide/cyclic GMP pathway in ovariectomized mice.

Heydarpour P, Salehi-Sadaghiani M, Javadi-Paydar M, Rahimian R, Fakhfouri G, Khosravi M, Khoshkish S, Gharedaghi MH, Ghasemi M, Dehpour AR.

Horm Behav. 2013 Feb;63(2):361-9. doi: 10.1016/j.yhbeh.2012.12.005. Epub 2012 Dec 19.

PMID:
23262264
13.

Aβ leads to Ca²⁺ signaling alterations and transcriptional changes in glial cells.

Grolla AA, Fakhfouri G, Balzaretti G, Marcello E, Gardoni F, Canonico PL, DiLuca M, Genazzani AA, Lim D.

Neurobiol Aging. 2013 Feb;34(2):511-22. doi: 10.1016/j.neurobiolaging.2012.05.005. Epub 2012 Jun 5.

PMID:
22673114
14.

WIN55212-2 attenuates amyloid-beta-induced neuroinflammation in rats through activation of cannabinoid receptors and PPAR-γ pathway.

Fakhfouri G, Ahmadiani A, Rahimian R, Grolla AA, Moradi F, Haeri A.

Neuropharmacology. 2012 Sep;63(4):653-66. doi: 10.1016/j.neuropharm.2012.05.013. Epub 2012 May 23.

PMID:
22634229
15.

How can 5-HT(3) receptor antagonists exert analgesic properties?

Norouzi A, Fakhfouri G, Rahimian R.

Acta Med Iran. 2012;50(4):225. No abstract available.

PMID:
22592570
16.

The NAMPT inhibitor FK866 reverts the damage in spinal cord injury.

Esposito E, Impellizzeri D, Mazzon E, Fakhfouri G, Rahimian R, Travelli C, Tron GC, Genazzani AA, Cuzzocrea S.

J Neuroinflammation. 2012 Apr 10;9:66. doi: 10.1186/1742-2094-9-66.

17.

Impact of 5-HT₃ receptor antagonists on peripheral and central diseases.

Fakhfouri G, Rahimian R, Ghia JE, Khan WI, Dehpour AR.

Drug Discov Today. 2012 Jul;17(13-14):741-7. doi: 10.1016/j.drudis.2012.02.009. Epub 2012 Feb 25. Review.

PMID:
22390946
18.

Tropisetron upregulates cannabinoid CB1 receptors in cerebellar granule cells: possible involvement of calcineurin.

Rahimian R, Dehpour AR, Fakhfouri G, Khorramizadeh MR, Ghia JE, Seyedabadi M, Caldarelli A, Mousavizadeh K, Forouzandeh M, Mehr SE.

Brain Res. 2011 Oct 12;1417:1-8. doi: 10.1016/j.brainres.2011.08.050. Epub 2011 Aug 27.

PMID:
21914553
19.

Sildenafil attenuates TNBS-induced colitis in rats: possible involvement of cGMP and KATP channels.

Fakhfouri G, Rahimian R, Hashemi S, Rasouli MR, Bahremand A, Mehr SE, Khorramizadeh MR, Dehpour AR.

Fundam Clin Pharmacol. 2012 Apr;26(2):190-3. doi: 10.1111/j.1472-8206.2011.00928.x.

PMID:
21777273
20.

The role of 5-HT(3) receptors in the additive anticonvulsant effects of citalopram and morphine on pentylenetetrazole-induced clonic seizures in mice.

Bahremand A, Payandemehr B, Rahimian R, Ziai P, Pourmand N, Loloee S, Ebrahimi A, Ghasemi A, Fakhfouri G, Ghasemi M, Dehpour AR.

Epilepsy Behav. 2011 Jun;21(2):122-7. doi: 10.1016/j.yebeh.2011.03.010. Epub 2011 Apr 30.

PMID:
21531632
21.

Tropisetron ameliorates ischemic brain injury in an embolic model of stroke.

Rahimian R, Daneshmand A, Mehr SE, Barzegar-Fallah A, Mohammadi-Rick S, Fakhfouri G, Shabanzadeh AP, Dehpour AR.

Brain Res. 2011 May 25;1392:101-9. doi: 10.1016/j.brainres.2011.03.053. Epub 2011 Mar 27.

PMID:
21447327
22.

Chronic lithium administration ameliorates 2,4,6-trinitrobenzene sulfonic acid-induced colitis in rats; potential role for adenosine triphosphate sensitive potassium channels.

Daneshmand A, Mohammadi H, Rahimian R, Habibollahi P, Fakhfouri G, Talab SS, Mehr SE, Dehpour AR.

J Gastroenterol Hepatol. 2011 Jul;26(7):1174-81. doi: 10.1111/j.1440-1746.2011.06719.x.

PMID:
21401719
23.

Adenosine A2A receptors and uric acid mediate protective effects of inosine against TNBS-induced colitis in rats.

Rahimian R, Fakhfouri G, Daneshmand A, Mohammadi H, Bahremand A, Rasouli MR, Mousavizadeh K, Dehpour AR.

Eur J Pharmacol. 2010 Dec 15;649(1-3):376-81. doi: 10.1016/j.ejphar.2010.09.044. Epub 2010 Sep 22.

PMID:
20868668
24.

Granisetron ameliorates acetic acid-induced colitis in rats.

Fakhfouri G, Rahimian R, Daneshmand A, Bahremand A, Rasouli MR, Dehpour AR, Mehr SE, Mousavizadeh K.

Hum Exp Toxicol. 2010 Apr;29(4):321-8. doi: 10.1177/0960327110362702. Epub 2010 Feb 12.

PMID:
20154102
25.

Lithium does not protect against spinal cord ischemia-reperfusion injury in rabbits.

Rasouli MR, Rahimian R, Fakhfouri G, Mehr SE, Tavangar SM, Dehpour AR.

Ann Vasc Surg. 2010 Feb;24(2):299-300. doi: 10.1016/j.avsg.2009.10.011. No abstract available.

PMID:
20142005
26.

Effect of pioglitazone on sciatic nerve ischemia/reperfusion injury in rats.

Rahimian R, Fakhfouri G, Rasouli MR, Nouri M, Nezami BG, Paydar MJ, Asadi-Amoli F, Dehpour AR.

Pediatr Neurosurg. 2009;45(2):126-31. doi: 10.1159/000209287. Epub 2009 Mar 21.

PMID:
19307747
27.

Anti-inflammatory effects of 5-HT receptor antagonist, tropisetron on experimental colitis in rats.

Mousavizadeh K, Rahimian R, Fakhfouri G, Aslani FS, Ghafourifar P.

Eur J Clin Invest. 2009 May;39(5):375-83. doi: 10.1111/j.1365-2362.2009.02102.x.

PMID:
19302562
28.

Ipsilateral common iliac artery plus femoral artery clamping for inducing sciatic nerve ischemia/reperfusion injury in rats: a reliable and simple method.

Nouri M, Rahimian R, Fakhfouri G, Rasouli MR, Mohammadi-Rick S, Barzegar-Fallah A, Asadi-Amoli F, Dehpour AR.

J Brachial Plex Peripher Nerve Inj. 2008 Dec 22;3:27. doi: 10.1186/1749-7221-3-27.

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