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Improving counterfactual reasoning with kernelised dynamic mixing models.

Parbhoo S, Gottesman O, Ross AS, Komorowski M, Faisal A, Bon I, Roth V, Doshi-Velez F.

PLoS One. 2018 Nov 12;13(11):e0205839. doi: 10.1371/journal.pone.0205839. eCollection 2018.


The Artificial Intelligence Clinician learns optimal treatment strategies for sepsis in intensive care.

Komorowski M, Celi LA, Badawi O, Gordon AC, Faisal AA.

Nat Med. 2018 Nov;24(11):1716-1720. doi: 10.1038/s41591-018-0213-5. Epub 2018 Oct 22.


Severe Exertional Dyspnea in an Ex-Smoker with a Large Apical Bulla.

Elbehairy AF, Faisal A, Ciavaglia CE, Kwok C, Reid K, Vincent SG, Domnik NJ, Neder JA, O'Donnell DE.

Ann Am Thorac Soc. 2018 Oct;15(10):1221-1228. doi: 10.1513/AnnalsATS.201804-288CC. No abstract available.


Decomposing sensorimotor variability changes in ageing and their connection to falls in older people.

Lin CH, Faisal AA.

Sci Rep. 2018 Sep 28;8(1):14546. doi: 10.1038/s41598-018-32648-z.


Introduction of a Methyl Group Curbs Metabolism of Pyrido[3,4- d]pyrimidine Monopolar Spindle 1 (MPS1) Inhibitors and Enables the Discovery of the Phase 1 Clinical Candidate N2-(2-Ethoxy-4-(4-methyl-4 H-1,2,4-triazol-3-yl)phenyl)-6-methyl- N8-neopentylpyrido[3,4- d]pyrimidine-2,8-diamine (BOS172722).

Woodward HL, Innocenti P, Cheung KJ, Hayes A, Roberts J, Henley AT, Faisal A, Mak GW, Box G, Westwood IM, Cronin N, Carter M, Valenti M, De Haven Brandon A, O'Fee L, Saville H, Schmitt J, Burke R, Broccatelli F, van Montfort RLM, Raynaud FI, Eccles SA, Linardopoulos S, Blagg J, Hoelder S.

J Med Chem. 2018 Sep 27;61(18):8226-8240. doi: 10.1021/acs.jmedchem.8b00690. Epub 2018 Sep 10.


Biogenic Synthesis of AgNPs with Saussurea lappa C.B. Clarke and Studies on Their Biochemical Properties.

Riaz M, Altaf M, Faisal A, Shekheli MA, Miana GA, Khan MQ, Shah MA, Ilyas SZ, Khan AA.

J Nanosci Nanotechnol. 2018 Dec 1;18(12):8392-8398. doi: 10.1166/jnn.2018.16414.


Pulmonary benign metastasizing leiomyoma: A case report.

Khan M, Faisal A, Ibrahim H, Barnes T, VanOtteren GM.

Respir Med Case Rep. 2018 May 3;24:117-121. doi: 10.1016/j.rmcr.2018.04.017. eCollection 2018.


Immune System Activation in Rheumatic Heart Disease.

Anam A, Faisal AWK, Afzal N, Shahzad F.

J Coll Physicians Surg Pak. 2018 Jul;28(7):518-522. doi: 10.29271/jcpsp.2018.07.518.


Traumatic Expulsion of Tracheal Rings: An Airway Emergency.

Ravid K, Heiser H, Faisal A, Cumbo-Nacheli G, Young B, Sethi S, Kumar A.

J Bronchology Interv Pulmonol. 2018 Jul;25(3):e34-e36. doi: 10.1097/LBR.0000000000000472. No abstract available.


CDK1 inhibition facilitates formation of syncytiotrophoblasts and expression of human Chorionic Gonadotropin.

Ullah R, Dar S, Ahmad T, de Renty C, Usman M, DePamphilis ML, Faisal A, Shahzad-Ul-Hussan S, Ullah Z.

Placenta. 2018 Jun;66:57-64. doi: 10.1016/j.placenta.2018.05.003. Epub 2018 May 17.


Challenges and Patterns of Seeking Primary Health Care in Slums of Karachi: A Disaster Lurking in Urban Shadows.

Aleemi AR, Khaliqui H, Faisal A.

Asia Pac J Public Health. 2018 Jul;30(5):479-490. doi: 10.1177/1010539518772132. Epub 2018 May 2.


Author Correction: Identification and characterization of SSE15206, a microtubule depolymerizing agent that overcomes multidrug resistance.

Manzoor S, Bilal A, Khan S, Ullah R, Iftikhar S, Emwas AH, Alazmi M, Gao X, Jawaid A, Saleem RSZ, Faisal A.

Sci Rep. 2018 Apr 18;8(1):6427. doi: 10.1038/s41598-018-24114-7.


Inspiratory muscle training reduces diaphragm activation and dyspnea during exercise in COPD.

Langer D, Ciavaglia C, Faisal A, Webb KA, Neder JA, Gosselink R, Dacha S, Topalovic M, Ivanova A, O'Donnell DE.

J Appl Physiol (1985). 2018 Aug 1;125(2):381-392. doi: 10.1152/japplphysiol.01078.2017. Epub 2018 Mar 15.


ATLANTIS - Attractor Landscape Analysis Toolbox for Cell Fate Discovery and Reprogramming.

Shah OS, Chaudhary MFA, Awan HA, Fatima F, Arshad Z, Amina B, Ahmed M, Hameed H, Furqan M, Khalid S, Faisal A, Chaudhary SU.

Sci Rep. 2018 Feb 23;8(1):3554. doi: 10.1038/s41598-018-22031-3.


Identification and characterization of SSE15206, a microtubule depolymerizing agent that overcomes multidrug resistance.

Manzoor S, Bilal A, Khan S, Ullah R, Iftikhar S, Emwas AH, Alazmi M, Gao X, Jawaid A, Saleem RSZ, Faisal A.

Sci Rep. 2018 Feb 19;8(1):3305. doi: 10.1038/s41598-018-21642-0. Erratum in: Sci Rep. 2018 Apr 18;8(1):6427.


Computer aided epitope design as a peptide vaccine component against Lassa virus.

Faisal AM, Imtiaz SH, Zerin T, Rahman T, Shekhar HU.

Bioinformation. 2017 Dec 31;13(12):417-429. doi: 10.6026/97320630013417. eCollection 2017.


Successful recovery from misdirection syndrome in nanophthalmic eyes by performing an anterior vitrectomy through the anterior chamber.

Faisal AA, Kamaruddin MI, Toda R, Kiuchi Y.

Int Ophthalmol. 2018 Jan 3. doi: 10.1007/s10792-017-0818-6. [Epub ahead of print]


Unraveling the Cause of Severe Exertional Dyspnea in a Heavy Smoker.

Elbehairy AF, Hockmann K, Ciavaglia CE, Faisal A, Hill E, Webb KA, Neder JA, O'Donnell DE.

Ann Am Thorac Soc. 2017 Dec;14(12):1849-1855. doi: 10.1513/AnnalsATS.201705-382CC. No abstract available.


Short communication: Diagnosis of lung cancer increases during the annual southeast Asian haze periods.

Hassan A, Latif MT, Soo CI, Faisal AH, Roslina AM, Andrea YLB, Hassan T.

Lung Cancer. 2017 Nov;113:1-3. doi: 10.1016/j.lungcan.2017.08.025. Epub 2017 Sep 1.


Increased respiratory neural drive and work of breathing in exercise-induced laryngeal obstruction.

Walsted ES, Faisal A, Jolley CJ, Swanton LL, Pavitt MJ, Luo YM, Backer V, Polkey MI, Hull JH.

J Appl Physiol (1985). 2018 Feb 1;124(2):356-363. doi: 10.1152/japplphysiol.00691.2017. Epub 2017 Nov 2.


Sensory-mechanical effects of a dual bronchodilator and its anticholinergic component in COPD.

O'Donnell DE, Elbehairy AF, Faisal A, Neder JA, Webb KA; Canadian Respiratory Research Network (CRRN).

Respir Physiol Neurobiol. 2018 Jan;247:116-125. doi: 10.1016/j.resp.2017.10.001. Epub 2017 Oct 7.


Electro-navigational bronchoscopy for bilateral peripheral lung lesions: A case report.

Faisal AH, Sopian AW, Tidi H.

Med J Malaysia. 2017 Aug;72(4):241-243.


Gaussian Process Autoregression for Simultaneous Proportional Multi-Modal Prosthetic Control With Natural Hand Kinematics.

Xiloyannis M, Gavriel C, Thomik AAC, Faisal AA.

IEEE Trans Neural Syst Rehabil Eng. 2017 Oct;25(10):1785-1801. doi: 10.1109/TNSRE.2017.2699598. Epub 2017 Aug 31.


Knee cartilage segmentation and thickness computation from ultrasound images.

Faisal A, Ng SC, Goh SL, Lai KW.

Med Biol Eng Comput. 2018 Apr;56(4):657-669. doi: 10.1007/s11517-017-1710-2. Epub 2017 Aug 29.


Multimodality registration of two-dimensional echocardiography and cardiac CT for mitral valve diagnosis and surgical planning.

Khalil A, Faisal A, Ng SC, Liew YM, Lai KW.

J Med Imaging (Bellingham). 2017 Jul;4(3):037001. doi: 10.1117/1.JMI.4.3.037001. Epub 2017 Aug 19.


Towards free 3D end-point control for robotic-assisted human reaching using binocular eye tracking.

Maimon-Dror RO, Fernandez-Quesada J, Zito GA, Konnaris C, Dziemian S, Faisal AA.

IEEE Int Conf Rehabil Robot. 2017 Jul;2017:1049-1054. doi: 10.1109/ICORR.2017.8009388.


"Wink to grasp" - comparing eye, voice & EMG gesture control of grasp with soft-robotic gloves.

Noronha B, Dziemian S, Zito GA, Konnaris C, Faisal AA.

IEEE Int Conf Rehabil Robot. 2017 Jul;2017:1043-1048. doi: 10.1109/ICORR.2017.8009387.


Synthesis and evaluation of modified chalcone based p53 stabilizing agents.

Iftikhar S, Khan S, Bilal A, Manzoor S, Abdullah M, Emwas AH, Sioud S, Gao X, Chotana GA, Faisal A, Saleem RSZ.

Bioorg Med Chem Lett. 2017 Sep 1;27(17):4101-4106. doi: 10.1016/j.bmcl.2017.07.042. Epub 2017 Jul 15.


Nicotine Exposure Augments Renal Toxicity of 5-aza-cytidine Through p66shc: Prevention by Resveratrol.

Arany I, Hall S, Faisal A, Dixit M.

Anticancer Res. 2017 Aug;37(8):4075-4079.


Understanding Health Seeking Behavior Of Health Care Professionals In Tertiary Care Hospitals In Pakistan.

Bana S, Yakoob J, Jivany N, Faisal A, Jawed H, Awan S.

J Ayub Med Coll Abbottabad. 2016 Jul-Sep;28(3):545-549.


Calcium-activated SK channels control firing regularity by modulating sodium channel availability in midbrain dopamine neurons.

Iyer R, Ungless MA, Faisal AA.

Sci Rep. 2017 Jul 12;7(1):5248. doi: 10.1038/s41598-017-05578-5.


Resting Physiological Correlates of Reduced Exercise Capacity in Smokers with Mild Airway Obstruction.

Elbehairy AF, Faisal A, Guenette JA, Jensen D, Webb KA, Ahmed R, Neder JA, O'Donnell DE; Canadian Respiratory Research Network (CRRN).

COPD. 2017 Jun;14(3):267-275. doi: 10.1080/15412555.2017.1281901. Epub 2017 Apr 3.


Characterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacy.

Faisal A, Mak GWY, Gurden MD, Xavier CPR, Anderhub SJ, Innocenti P, Westwood IM, Naud S, Hayes A, Box G, Valenti MR, De Haven Brandon AK, O'Fee L, Schmitt J, Woodward HL, Burke R, vanMontfort RLM, Blagg J, Raynaud FI, Eccles SA, Hoelder S, Linardopoulos S.

Br J Cancer. 2017 Apr 25;116(9):1166-1176. doi: 10.1038/bjc.2017.75. Epub 2017 Mar 23.


Detecting knee osteoarthritis and its discriminating parameters using random forests.

Kotti M, Duffell LD, Faisal AA, McGregor AH.

Med Eng Phys. 2017 May;43:19-29. doi: 10.1016/j.medengphy.2017.02.004. Epub 2017 Feb 24.


Remediation of groundwater contaminated with the lead-phenol binary system by granular dead anaerobic sludge-permeable reactive barrier.

Faisal AAH, Abd Ali ZT.

Environ Technol. 2017 Oct;38(20):2534-2542. doi: 10.1080/09593330.2016.1270355. Epub 2016 Dec 28.


2D to 3D fusion of echocardiography and cardiac CT for TAVR and TAVI image guidance.

Khalil A, Faisal A, Lai KW, Ng SC, Liew YM.

Med Biol Eng Comput. 2017 Aug;55(8):1317-1326. doi: 10.1007/s11517-016-1594-6. Epub 2016 Nov 9.


Internal states drive nutrient homeostasis by modulating exploration-exploitation trade-off.

Corrales-Carvajal VM, Faisal AA, Ribeiro C.

Elife. 2016 Oct 22;5. pii: e19920. doi: 10.7554/eLife.19920.


Exertional dyspnoea in COPD: the clinical utility of cardiopulmonary exercise testing.

O'Donnell DE, Elbehairy AF, Faisal A, Webb KA, Neder JA, Mahler DA.

Eur Respir Rev. 2016 Sep;25(141):333-47. doi: 10.1183/16000617.0054-2016. Review. Erratum in: Eur Respir Rev. 2016 Dec;25(142):513.


Mechanisms of exertional dyspnoea in symptomatic smokers without COPD.

Elbehairy AF, Guenette JA, Faisal A, Ciavaglia CE, Webb KA, Jensen D, Ramsook AH, Neder JA, O'Donnell DE; Canadian Respiratory Research Network.

Eur Respir J. 2016 Sep;48(3):694-705. doi: 10.1183/13993003.00077-2016. Epub 2016 Aug 4.


Natural products from Cuscuta reflexa Roxb. with antiproliferation activities in HCT116 colorectal cell lines.

Riaz M, Bilal A, Ali MS, Fatima I, Faisal A, Sherkheli MA, Asghar A.

Nat Prod Res. 2017 Mar;31(5):583-587. doi: 10.1080/14786419.2016.1198349. Epub 2016 Jul 22.


Aurora B prevents premature removal of spindle assembly checkpoint proteins from the kinetochore: A key role for Aurora B in mitosis.

Gurden MD, Anderhub SJ, Faisal A, Linardopoulos S.

Oncotarget. 2016 Jul 18;9(28):19525-19542. doi: 10.18632/oncotarget.10657. eCollection 2018 Apr 13.


Increasing the field of view in grating based X-ray phase contrast imaging using stitched gratings.

Meiser J, Willner M, Schröter T, Hofmann A, Rieger J, Koch F, Birnbacher L, Schüttler M, Kunka D, Meyer P, Faisal A, Amberger M, Duttenhofer T, Weber T, Hipp A, Ehn S, Walter M, Herzen J, Schulz J, Pfeiffer F, Mohr J.

J Xray Sci Technol. 2016 Mar 17;24(3):379-88. doi: 10.3233/XST-160552.


Rapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization Approach.

Innocenti P, Woodward HL, Solanki S, Naud S, Westwood IM, Cronin N, Hayes A, Roberts J, Henley AT, Baker R, Faisal A, Mak GW, Box G, Valenti M, De Haven Brandon A, O'Fee L, Saville H, Schmitt J, Matijssen B, Burke R, van Montfort RL, Raynaud FI, Eccles SA, Linardopoulos S, Blagg J, Hoelder S.

J Med Chem. 2016 Apr 28;59(8):3671-88. doi: 10.1021/acs.jmedchem.5b01811. Epub 2016 Apr 7.


Corrigendum. Prolonged ischaemia impairs muscle blood flow and oxygen uptake dynamics during subsequent heavy exercise.

Faisal A, Dyson KS, Hughson RL.

J Physiol. 2016 Apr 1;594(7):1957. doi: 10.1113/JP272229. Epub 2016 Mar 9. No abstract available.


The Automatic Neuroscientist: A framework for optimizing experimental design with closed-loop real-time fMRI.

Lorenz R, Monti RP, Violante IR, Anagnostopoulos C, Faisal AA, Montana G, Leech R.

Neuroimage. 2016 Apr 1;129:320-334. doi: 10.1016/j.neuroimage.2016.01.032. Epub 2016 Jan 21.


Robotic psychophysics system for assessment, diagnosis and rehabilitation of the neurological causes of falls in the elderly.

Lin CH, Faisal AA.

Conf Proc IEEE Eng Med Biol Soc. 2015 Aug;2015:3731-4. doi: 10.1109/EMBC.2015.7319204.


Note: Gratings on low absorbing substrates for x-ray phase contrast imaging.

Koch FJ, Schröter TJ, Kunka D, Meyer P, Meiser J, Faisal A, Khalil MI, Birnbacher L, Viermetz M, Walter M, Schulz J, Pfeiffer F, Mohr J.

Rev Sci Instrum. 2015 Dec;86(12):126114. doi: 10.1063/1.4939055.


Headway Duo microcatheter for cerebral arteriovenous malformation embolization with n-BCA.

Heit JJ, Faisal AG, Telischak NA, Choudhri O, Do HM.

J Neurointerv Surg. 2016 Nov;8(11):1181-1185. doi: 10.1136/neurintsurg-2015-012094. Epub 2015 Nov 24.


Myxopapillary ependymomas in children: imaging, treatment and outcomes.

Bandopadhayay P, Silvera VM, Ciarlini PD, Malkin H, Bi WL, Bergthold G, Faisal AM, Ullrich NJ, Marcus K, Scott RM, Beroukhim R, Manley PE, Chi SN, Ligon KL, Goumnerova LC, Kieran MW.

J Neurooncol. 2016 Jan;126(1):165-74.


Common Mechanisms of Dyspnea in Chronic Interstitial and Obstructive Lung Disorders.

Faisal A, Alghamdi BJ, Ciavaglia CE, Elbehairy AF, Webb KA, Ora J, Neder JA, O'Donnell DE.

Am J Respir Crit Care Med. 2016 Feb 1;193(3):299-309. doi: 10.1164/rccm.201504-0841OC.


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