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Items: 1 to 50 of 159

1.

The molecular origin and taxonomy of mucinous ovarian carcinoma.

Cheasley D, Wakefield MJ, Ryland GL, Allan PE, Alsop K, Amarasinghe KC, Ananda S, Anglesio MS, Au-Yeung G, Böhm M, Bowtell DDL, Brand A, Chenevix-Trench G, Christie M, Chiew YE, Churchman M, DeFazio A, Demeo R, Dudley R, Fairweather N, Fedele CG, Fereday S, Fox SB, Gilks CB, Gourley C, Hacker NF, Hadley AM, Hendley J, Ho GY, Hughes S, Hunstman DG, Hunter SM, Jobling TW, Kalli KR, Kaufmann SH, Kennedy CJ, Köbel M, Le Page C, Li J, Lupat R, McNally OM, McAlpine JN, Mes-Masson AM, Mileshkin L, Provencher DM, Pyman J, Rahimi K, Rowley SM, Salazar C, Samimi G, Saunders H, Semple T, Sharma R, Sharpe AJ, Stephens AN, Thio N, Torres MC, Traficante N, Xing Z, Zethoven M, Antill YC, Scott CL, Campbell IG, Gorringe KL.

Nat Commun. 2019 Sep 2;10(1):3935. doi: 10.1038/s41467-019-11862-x.

2.

Keratin-14 (KRT14) Positive Leader Cells Mediate Mesothelial Clearance and Invasion by Ovarian Cancer Cells.

Bilandzic M, Rainczuk A, Green E, Fairweather N, Jobling TW, Plebanski M, Stephens AN.

Cancers (Basel). 2019 Aug 22;11(9). pii: E1228. doi: 10.3390/cancers11091228.

3.

The S-layer protein of a Clostridium difficile SLCT-11 strain displays a complex glycan required for normal cell growth and morphology.

Richards E, Bouché L, Panico M, Arbeloa A, Vinogradov E, Morris H, Wren B, Logan SM, Dell A, Fairweather NF.

J Biol Chem. 2018 Nov 23;293(47):18123-18137. doi: 10.1074/jbc.RA118.004530. Epub 2018 Oct 1.

4.

Discovery and Validation of Novel Protein Biomarkers in Ovarian Cancer Patient Urine.

Sandow JJ, Rainczuk A, Infusini G, Makanji M, Bilandzic M, Wilson AL, Fairweather N, Stanton PG, Garama D, Gough D, Jobling TW, Webb AI, Stephens AN.

Proteomics Clin Appl. 2018 May;12(3):e1700135. doi: 10.1002/prca.201700135. Epub 2018 Mar 2.

PMID:
29426060
5.

Clostridium sordellii Pathogenicity Locus Plasmid pCS1-1 Encodes a Novel Clostridial Conjugation Locus.

Vidor CJ, Watts TD, Adams V, Bulach D, Couchman E, Rood JI, Fairweather NF, Awad M, Lyras D.

MBio. 2018 Jan 16;9(1). pii: e01761-17. doi: 10.1128/mBio.01761-17.

6.

Evaluation of a Brief Team Training Intervention in Surgery: A Mixed-Methods Study.

Gillespie BM, Steel C, Kang E, Harbeck E, Nikolic K, Fairweather N, Chaboyer W.

AORN J. 2017 Dec;106(6):513-522. doi: 10.1016/j.aorn.2017.09.013.

PMID:
29173376
7.

Disparate subcellular location of putative sortase substrates in Clostridium difficile.

Peltier J, Shaw HA, Wren BW, Fairweather NF.

Sci Rep. 2017 Aug 23;7(1):9204. doi: 10.1038/s41598-017-08322-1.

8.

Changes in surgical team performance and safety climate attitudes following expansion of perioperative services: a repeated-measures study.

Gillespie BM, Harbeck E, Kang E, Steel C, Fairweather N, Chaboyer W.

Aust Health Rev. 2018 Dec;42(6):703-708. doi: 10.1071/AH17079.

PMID:
28793951
9.

Effects of a Brief Team Training Program on Surgical Teams' Nontechnical Skills: An Interrupted Time-Series Study.

Gillespie BM, Harbeck E, Kang E, Steel C, Fairweather N, Panuwatwanich K, Chaboyer W.

J Patient Saf. 2017 Apr 27. doi: 10.1097/PTS.0000000000000361. [Epub ahead of print]

PMID:
28452912
10.

Correlates of non-technical skills in surgery: a prospective study.

Gillespie BM, Harbeck E, Kang E, Steel C, Fairweather N, Chaboyer W.

BMJ Open. 2017 Jan 30;7(1):e014480. doi: 10.1136/bmjopen-2016-014480.

11.

Lighting Up Clostridium Difficile: Reporting Gene Expression Using Fluorescent Lov Domains.

Buckley AM, Jukes C, Candlish D, Irvine JJ, Spencer J, Fagan RP, Roe AJ, Christie JM, Fairweather NF, Douce GR.

Sci Rep. 2016 Mar 21;6:23463. doi: 10.1038/srep23463.

12.

The SpoIIQ-SpoIIIAH complex of Clostridium difficile controls forespore engulfment and late stages of gene expression and spore morphogenesis.

Serrano M, Crawshaw AD, Dembek M, Monteiro JM, Pereira FC, Pinho MG, Fairweather NF, Salgado PS, Henriques AO.

Mol Microbiol. 2016 Apr;100(1):204-28. doi: 10.1111/mmi.13311. Epub 2016 Feb 12.

13.

Increased toxin expression in a Clostridium difficile mfd mutant.

Willing SE, Richards EJ, Sempere L, Dale AG, Cutting SM, Fairweather NF.

BMC Microbiol. 2015 Dec 18;15:280. doi: 10.1186/s12866-015-0611-5.

14.

Quantitative Lipoproteomics in Clostridium difficile Reveals a Role for Lipoproteins in Sporulation.

Charlton TM, Kovacs-Simon A, Michell SL, Fairweather NF, Tate EW.

Chem Biol. 2015 Nov 19;22(11):1562-1573. doi: 10.1016/j.chembiol.2015.10.006. Epub 2015 Nov 12.

15.

Cyclic diGMP regulates production of sortase substrates of Clostridium difficile and their surface exposure through ZmpI protease-mediated cleavage.

Peltier J, Shaw HA, Couchman EC, Dawson LF, Yu L, Choudhary JS, Kaever V, Wren BW, Fairweather NF.

J Biol Chem. 2015 Oct 2;290(40):24453-69. doi: 10.1074/jbc.M115.665091. Epub 2015 Aug 17.

16.

The Clostridium difficile cell wall protein CwpV confers phase-variable phage resistance.

Sekulovic O, Ospina Bedoya M, Fivian-Hughes AS, Fairweather NF, Fortier LC.

Mol Microbiol. 2015 Oct;98(2):329-42. doi: 10.1111/mmi.13121. Epub 2015 Aug 8.

17.

Clostridium sordellii genome analysis reveals plasmid localized toxin genes encoded within pathogenicity loci.

Couchman EC, Browne HP, Dunn M, Lawley TD, Songer JG, Hall V, Petrovska L, Vidor C, Awad M, Lyras D, Fairweather NF.

BMC Genomics. 2015 May 16;16:392. doi: 10.1186/s12864-015-1613-2.

18.

High-throughput analysis of gene essentiality and sporulation in Clostridium difficile.

Dembek M, Barquist L, Boinett CJ, Cain AK, Mayho M, Lawley TD, Fairweather NF, Fagan RP.

MBio. 2015 Feb 24;6(2):e02383. doi: 10.1128/mBio.02383-14.

19.

Clostridium difficile surface proteins are anchored to the cell wall using CWB2 motifs that recognise the anionic polymer PSII.

Willing SE, Candela T, Shaw HA, Seager Z, Mesnage S, Fagan RP, Fairweather NF.

Mol Microbiol. 2015 May;96(3):596-608. doi: 10.1111/mmi.12958. Epub 2015 Mar 6.

20.

Iron-based catalysts for the hydrogenation of esters to alcohols.

Chakraborty S, Dai H, Bhattacharya P, Fairweather NT, Gibson MS, Krause JA, Guan H.

J Am Chem Soc. 2014 Jun 4;136(22):7869-72. doi: 10.1021/ja504034q. Epub 2014 May 22.

PMID:
24846811
21.

Effect of using a safety checklist on patient complications after surgery: a systematic review and meta-analysis.

Gillespie BM, Chaboyer W, Thalib L, John M, Fairweather N, Slater K.

Anesthesiology. 2014 Jun;120(6):1380-9. doi: 10.1097/ALN.0000000000000232. Review.

PMID:
24845919
22.

The spore-associated protein BclA1 affects the susceptibility of animals to colonization and infection by Clostridium difficile.

Phetcharaburanin J, Hong HA, Colenutt C, Bianconi I, Sempere L, Permpoonpattana P, Smith K, Dembek M, Tan S, Brisson MC, Brisson AR, Fairweather NF, Cutting SM.

Mol Microbiol. 2014 Jun;92(5):1025-38. doi: 10.1111/mmi.12611. Epub 2014 Apr 24.

23.

Biogenesis and functions of bacterial S-layers.

Fagan RP, Fairweather NF.

Nat Rev Microbiol. 2014 Mar;12(3):211-22. doi: 10.1038/nrmicro3213. Epub 2014 Feb 10. Review.

24.

The utility of isotope-coded protein labeling for prioritization of proteins found in ovarian cancer patient urine.

Rainczuk A, Condina M, Pelzing M, Dolman S, Rao J, Fairweather N, Jobling T, Stephens AN.

J Proteome Res. 2013 Sep 6;12(9):4074-88. doi: 10.1021/pr400618v. Epub 2013 Aug 16.

PMID:
23952987
25.

Evidence for the antagonistic form of CXC-motif chemokine CXCL10 in serous epithelial ovarian tumours.

Rainczuk A, Rao JR, Gathercole JL, Fairweather NJ, Chu S, Masadah R, Jobling TW, Deb-Choudhury S, Dyer J, Stephens AN.

Int J Cancer. 2014 Feb 1;134(3):530-41. doi: 10.1002/ijc.28393. Epub 2013 Aug 28.

26.

Transcriptional analysis of temporal gene expression in germinating Clostridium difficile 630 endospores.

Dembek M, Stabler RA, Witney AA, Wren BW, Fairweather NF.

PLoS One. 2013 May 15;8(5):e64011. doi: 10.1371/journal.pone.0064011. Print 2013.

27.

Team communications in surgery - creating a culture of safety.

Gillespie BM, Gwinner K, Chaboyer W, Fairweather N.

J Interprof Care. 2013 Sep;27(5):387-93. doi: 10.3109/13561820.2013.784243. Epub 2013 May 14.

PMID:
23672607
28.

Building shared situational awareness in surgery through distributed dialog.

Gillespie BM, Gwinner K, Fairweather N, Chaboyer W.

J Multidiscip Healthc. 2013 Mar 20;6:109-18. doi: 10.2147/JMDH.S40710. Print 2013.

29.

CbpA: a novel surface exposed adhesin of Clostridium difficile targeting human collagen.

Tulli L, Marchi S, Petracca R, Shaw HA, Fairweather NF, Scarselli M, Soriani M, Leuzzi R.

Cell Microbiol. 2013 Oct;15(10):1674-87. doi: 10.1111/cmi.12139. Epub 2013 Apr 11.

PMID:
23517059
30.

Functional characterization of Clostridium difficile spore coat proteins.

Permpoonpattana P, Phetcharaburanin J, Mikelsone A, Dembek M, Tan S, Brisson MC, La Ragione R, Brisson AR, Fairweather N, Hong HA, Cutting SM.

J Bacteriol. 2013 Apr;195(7):1492-503. doi: 10.1128/JB.02104-12. Epub 2013 Jan 18.

31.

In recurrent C. difficile, the CRP response to the primary C. difficile infection predicts whether the same strain or a different strain will cause a second infection.

Chen K, d'Arc S, Setty N, Bamford K, Fairweather N, Tyrrell-Price J.

Dig Dis Sci. 2013 Jun;58(6):1683-8. doi: 10.1007/s10620-012-2534-4. Epub 2013 Jan 11.

PMID:
23306854
32.

The Clostridium difficile spo0A gene is a persistence and transmission factor.

Deakin LJ, Clare S, Fagan RP, Dawson LF, Pickard DJ, West MR, Wren BW, Fairweather NF, Dougan G, Lawley TD.

Infect Immun. 2012 Aug;80(8):2704-11. doi: 10.1128/IAI.00147-12. Epub 2012 May 21.

33.

Interruptions and miscommunications in surgery: an observational study.

Gillespie BM, Chaboyer W, Fairweather N.

AORN J. 2012 May;95(5):576-90. doi: 10.1016/j.aorn.2012.02.012.

PMID:
22541769
34.

A single-dose cytomegalovirus-based vaccine encoding tetanus toxin fragment C induces sustained levels of protective tetanus toxin antibodies in mice.

Tierney R, Nakai T, Parkins CJ, Caposio P, Fairweather NF, Sesardic D, Jarvis MA.

Vaccine. 2012 Apr 26;30(20):3047-52. doi: 10.1016/j.vaccine.2012.02.043. Epub 2012 Mar 10.

PMID:
22414558
35.

Clostridium difficile cell wall protein CwpV undergoes enzyme-independent intramolecular autoproteolysis.

Dembek M, Reynolds CB, Fairweather NF.

J Biol Chem. 2012 Jan 6;287(2):1538-44. doi: 10.1074/jbc.M111.302463. Epub 2011 Nov 28.

36.

Factors that influence the expected length of operation: results of a prospective study.

Gillespie BM, Chaboyer W, Fairweather N.

BMJ Qual Saf. 2012 Jan;21(1):3-12. doi: 10.1136/bmjqs-2011-000169. Epub 2011 Oct 14.

PMID:
22003174
37.

Novel inhibitors of surface layer processing in Clostridium difficile.

Tam Dang TH, Fagan RP, Fairweather NF, Tate EW.

Bioorg Med Chem. 2012 Jan 15;20(2):614-21. doi: 10.1016/j.bmc.2011.06.042. Epub 2011 Jun 21.

38.

Clostridium difficile has two parallel and essential Sec secretion systems.

Fagan RP, Fairweather NF.

J Biol Chem. 2011 Aug 5;286(31):27483-93. doi: 10.1074/jbc.M111.263889. Epub 2011 Jun 9.

39.

The Clostridium difficile cell wall protein CwpV is antigenically variable between strains, but exhibits conserved aggregation-promoting function.

Reynolds CB, Emerson JE, de la Riva L, Fagan RP, Fairweather NF.

PLoS Pathog. 2011 Apr;7(4):e1002024. doi: 10.1371/journal.ppat.1002024. Epub 2011 Apr 21.

40.

Roles of cysteine proteases Cwp84 and Cwp13 in biogenesis of the cell wall of Clostridium difficile.

de la Riva L, Willing SE, Tate EW, Fairweather NF.

J Bacteriol. 2011 Jul;193(13):3276-85. doi: 10.1128/JB.00248-11. Epub 2011 Apr 29.

41.

Immunization with Bacillus spores expressing toxin A peptide repeats protects against infection with Clostridium difficile strains producing toxins A and B.

Permpoonpattana P, Hong HA, Phetcharaburanin J, Huang JM, Cook J, Fairweather NF, Cutting SM.

Infect Immun. 2011 Jun;79(6):2295-302. doi: 10.1128/IAI.00130-11. Epub 2011 Apr 11.

42.

A proposed nomenclature for cell wall proteins of Clostridium difficile.

Fagan RP, Janoir C, Collignon A, Mastrantonio P, Poxton IR, Fairweather NF.

J Med Microbiol. 2011 Aug;60(Pt 8):1225-8. doi: 10.1099/jmm.0.028472-0. Epub 2011 Jan 20.

PMID:
21252271
43.

Dissecting the cell surface.

Fagan R, Fairweather N.

Methods Mol Biol. 2010;646:117-34. doi: 10.1007/978-1-60327-365-7_8.

PMID:
20597006
44.

Characterisation of a panel of anti-tetanus toxin single-chain Fvs reveals cooperative binding.

Scott N, Qazi O, Wright MJ, Fairweather NF, Deonarain MP.

Mol Immunol. 2010 Jun;47(10):1931-41. doi: 10.1016/j.molimm.2010.02.020. Epub 2010 Apr 22.

45.

The enteropathogenic Escherichia coli effector NleH inhibits apoptosis induced by Clostridium difficile toxin B.

Robinson KS, Mousnier A, Hemrajani C, Fairweather N, Berger CN, Frankel G.

Microbiology. 2010 Jun;156(Pt 6):1815-23. doi: 10.1099/mic.0.037259-0. Epub 2010 Mar 11.

46.

Four distinct structural domains in Clostridium difficile toxin B visualized using SAXS.

Albesa-Jové D, Bertrand T, Carpenter EP, Swain GV, Lim J, Zhang J, Haire LF, Vasisht N, Braun V, Lange A, von Eichel-Streiber C, Svergun DI, Fairweather NF, Brown KA.

J Mol Biol. 2010 Mar 12;396(5):1260-70. doi: 10.1016/j.jmb.2010.01.012. Epub 2010 Jan 11.

PMID:
20070948
47.

Chemical probes of surface layer biogenesis in Clostridium difficile.

Dang TH, de la Riva L, Fagan RP, Storck EM, Heal WP, Janoir C, Fairweather NF, Tate EW.

ACS Chem Biol. 2010 Mar 19;5(3):279-85. doi: 10.1021/cb9002859.

48.

Distinctive profiles of infection and pathology in hamsters infected with Clostridium difficile strains 630 and B1.

Goulding D, Thompson H, Emerson J, Fairweather NF, Dougan G, Douce GR.

Infect Immun. 2009 Dec;77(12):5478-85. doi: 10.1128/IAI.00551-09. Epub 2009 Sep 14.

49.

A novel genetic switch controls phase variable expression of CwpV, a Clostridium difficile cell wall protein.

Emerson JE, Reynolds CB, Fagan RP, Shaw HA, Goulding D, Fairweather NF.

Mol Microbiol. 2009 Nov;74(3):541-56. doi: 10.1111/j.1365-2958.2009.06812.x. Epub 2009 Jul 28.

50.

Antibiotic treatment of clostridium difficile carrier mice triggers a supershedder state, spore-mediated transmission, and severe disease in immunocompromised hosts.

Lawley TD, Clare S, Walker AW, Goulding D, Stabler RA, Croucher N, Mastroeni P, Scott P, Raisen C, Mottram L, Fairweather NF, Wren BW, Parkhill J, Dougan G.

Infect Immun. 2009 Sep;77(9):3661-9. doi: 10.1128/IAI.00558-09. Epub 2009 Jun 29.

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