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Items: 40

1.

Fluorescent antibiotics, vomocytosis, vaccine candidates and the inflammasome.

Lundie RJ, Helbig KJ, Pearson JS, Fairfax KA.

Clin Transl Immunology. 2019 Nov 1;8(11):e01083. doi: 10.1002/cti2.1083. eCollection 2019.

2.

IL-4 promotes stromal cell expansion and is critical for development of a type-2, but not a type 1 immune response.

Cortes-Selva D, Ready A, Gibbs L, Rajwa B, Fairfax KC.

Eur J Immunol. 2019 Mar;49(3):428-442. doi: 10.1002/eji.201847789. Epub 2019 Jan 3.

PMID:
30575951
3.

Schistosoma mansoni Infection-Induced Transcriptional Changes in Hepatic Macrophage Metabolism Correlate With an Athero-Protective Phenotype.

Cortes-Selva D, Elvington AF, Ready A, Rajwa B, Pearce EJ, Randolph GJ, Fairfax KC.

Front Immunol. 2018 Nov 12;9:2580. doi: 10.3389/fimmu.2018.02580. eCollection 2018.

4.

Haemopedia RNA-seq: a database of gene expression during haematopoiesis in mice and humans.

Choi J, Baldwin TM, Wong M, Bolden JE, Fairfax KA, Lucas EC, Cole R, Biben C, Morgan C, Ramsay KA, Ng AP, Kauppi M, Corcoran LM, Shi W, Wilson N, Wilson MJ, Alexander WS, Hilton DJ, de Graaf CA.

Nucleic Acids Res. 2019 Jan 8;47(D1):D780-D785. doi: 10.1093/nar/gky1020.

5.

Transcriptional profiling of eosinophil subsets in interleukin-5 transgenic mice.

Fairfax KA, Bolden JE, Robinson AJ, Lucas EC, Baldwin TM, Ramsay KA, Cole R, Hilton DJ, de Graaf CA.

J Leukoc Biol. 2018 Jul;104(1):195-204. doi: 10.1002/JLB.6MA1117-451R. Epub 2018 May 14.

6.

Identification of a Siglec-F+ granulocyte-macrophage progenitor.

Bolden JE, Lucas EC, Zhou G, O'Sullivan JA, de Graaf CA, McKenzie MD, Di Rago L, Baldwin TM, Shortt J, Alexander WS, Bochner BS, Ritchie ME, Hilton DJ, Fairfax KA.

J Leukoc Biol. 2018 Jul;104(1):123-133. doi: 10.1002/JLB.1MA1217-475R. Epub 2018 Apr 12.

7.

Vitamin D Receptor-Dependent Signaling Protects Mice From Dextran Sulfate Sodium-Induced Colitis.

Wang F, Johnson RL, DeSmet ML, Snyder PW, Fairfax KC, Fleet JC.

Endocrinology. 2017 Jun 1;158(6):1951-1963. doi: 10.1210/en.2016-1913.

8.

Assessing Immune-Related Adverse Events of Efficacious Combination Immunotherapies in Preclinical Models of Cancer.

Liu J, Blake SJ, Harjunpää H, Fairfax KA, Yong MC, Allen S, Kohrt HE, Takeda K, Smyth MJ, Teng MW.

Cancer Res. 2016 Sep 15;76(18):5288-301. doi: 10.1158/0008-5472.CAN-16-0194. Epub 2016 Aug 8.

9.

Haemopedia: An Expression Atlas of Murine Hematopoietic Cells.

de Graaf CA, Choi J, Baldwin TM, Bolden JE, Fairfax KA, Robinson AJ, Biben C, Morgan C, Ramsay K, Ng AP, Kauppi M, Kruse EA, Sargeant TJ, Seidenman N, D'Amico A, D'Ombrain MC, Lucas EC, Koernig S, Baz Morelli A, Wilson MJ, Dower SK, Williams B, Heazlewood SY, Hu Y, Nilsson SK, Wu L, Smyth GK, Alexander WS, Hilton DJ.

Stem Cell Reports. 2016 Sep 13;7(3):571-582. doi: 10.1016/j.stemcr.2016.07.007. Epub 2016 Aug 4.

10.

Id2 and E Proteins Orchestrate the Initiation and Maintenance of MLL-Rearranged Acute Myeloid Leukemia.

Ghisi M, Kats L, Masson F, Li J, Kratina T, Vidacs E, Gilan O, Doyle MA, Newbold A, Bolden JE, Fairfax KA, de Graaf CA, Firth M, Zuber J, Dickins RA, Corcoran LM, Dawson MA, Belz GT, Johnstone RW.

Cancer Cell. 2016 Jul 11;30(1):59-74. doi: 10.1016/j.ccell.2016.05.019. Epub 2016 Jun 30.

11.

NFκB1 is essential to prevent the development of multiorgan autoimmunity by limiting IL-6 production in follicular B cells.

de Valle E, Grigoriadis G, O'Reilly LA, Willis SN, Maxwell MJ, Corcoran LM, Tsantikos E, Cornish JK, Fairfax KA, Vasanthakumar A, Febbraio MA, Hibbs ML, Pellegrini M, Banerjee A, Hodgkin PD, Kallies A, Mackay F, Strasser A, Gerondakis S, Gugasyan R.

J Exp Med. 2016 Apr 4;213(4):621-41. doi: 10.1084/jem.20151182. Epub 2016 Mar 28.

12.

Migratory CD103+ dendritic cells suppress helminth-driven type 2 immunity through constitutive expression of IL-12.

Everts B, Tussiwand R, Dreesen L, Fairfax KC, Huang SC, Smith AM, O'Neill CM, Lam WY, Edelson BT, Urban JF Jr, Murphy KM, Pearce EJ.

J Exp Med. 2016 Jan 11;213(1):35-51. doi: 10.1084/jem.20150235. Epub 2015 Dec 28.

13.

BAFF-driven autoimmunity requires CD19 expression.

Fairfax KA, Tsantikos E, Figgett WA, Vincent FB, Quah PS, LePage M, Hibbs ML, Mackay F.

J Autoimmun. 2015 Aug;62:1-10. doi: 10.1016/j.jaut.2015.06.001. Epub 2015 Jun 20.

PMID:
26103922
14.

Deleting the BAFF receptor TACI protects against systemic lupus erythematosus without extensive reduction of B cell numbers.

Figgett WA, Deliyanti D, Fairfax KA, Quah PS, Wilkinson-Berka JL, Mackay F.

J Autoimmun. 2015 Jul;61:9-16. doi: 10.1016/j.jaut.2015.04.007. Epub 2015 May 29.

PMID:
26027434
15.

IL-4-secreting secondary T follicular helper (Tfh) cells arise from memory T cells, not persisting Tfh cells, through a B cell-dependent mechanism.

Fairfax KC, Everts B, Amiel E, Smith AM, Schramm G, Haas H, Randolph GJ, Taylor JJ, Pearce EJ.

J Immunol. 2015 Apr 1;194(7):2999-3010. doi: 10.4049/jimmunol.1401225. Epub 2015 Feb 23.

16.

The RNA-binding protein HuR is essential for the B cell antibody response.

Diaz-Muñoz MD, Bell SE, Fairfax K, Monzon-Casanova E, Cunningham AF, Gonzalez-Porta M, Andrews SR, Bunik VI, Zarnack K, Curk T, Heggermont WA, Heymans S, Gibson GE, Kontoyiannis DL, Ule J, Turner M.

Nat Immunol. 2015 Apr;16(4):415-25. doi: 10.1038/ni.3115. Epub 2015 Feb 23.

17.

Molecular cloning and characterization of a nematode polyprotein antigen/allergen from the human and animal hookworm Ancylostoma ceylanicum.

Fairfax KC, Harrison LM, Cappello M.

Mol Biochem Parasitol. 2014 Nov;198(1):37-44. doi: 10.1016/j.molbiopara.2014.11.005. Epub 2014 Dec 4.

18.

IL-10 regulates Aicda expression through miR-155.

Fairfax KA, Gantier MP, Mackay F, Williams BR, McCoy CE.

J Leukoc Biol. 2015 Jan;97(1):71-8. doi: 10.1189/jlb.2A0314-178R. Epub 2014 Nov 7.

PMID:
25381386
19.

The tyrosine kinase Lyn limits the cytokine responsiveness of plasma cells to restrict their accumulation in mice.

Infantino S, Jones SA, Walker JA, Maxwell MJ, Light A, O'Donnell K, Tsantikos E, Peperzak V, Phesse T, Ernst M, Mackay F, Hibbs ML, Fairfax KA, Tarlinton DM.

Sci Signal. 2014 Aug 12;7(338):ra77. doi: 10.1126/scisignal.2005105.

PMID:
25118329
20.

Gata6 regulates aspartoacylase expression in resident peritoneal macrophages and controls their survival.

Gautier EL, Ivanov S, Williams JW, Huang SC, Marcelin G, Fairfax K, Wang PL, Francis JS, Leone P, Wilson DB, Artyomov MN, Pearce EJ, Randolph GJ.

J Exp Med. 2014 Jul 28;211(8):1525-31. doi: 10.1084/jem.20140570. Epub 2014 Jul 14.

21.

CD19 differentially regulates BCR signalling through the recruitment of PI3K.

Xu Y, Fairfax K, Light A, Huntington ND, Tarlinton DM.

Autoimmunity. 2014 Nov;47(7):430-7. doi: 10.3109/08916934.2014.921810. Epub 2014 Jun 23.

PMID:
24953501
22.

Gene therapy delivery of myelin oligodendrocyte glycoprotein (MOG) via hematopoietic stem cell transfer induces MOG-specific B cell deletion.

Chung JY, Figgett W, Fairfax K, Bernard C, Chan J, Toh BH, Mackay F, Alderuccio F.

J Immunol. 2014 Mar 15;192(6):2593-601. doi: 10.4049/jimmunol.1203563. Epub 2014 Feb 14.

23.

Regulation of the development of the hepatic B cell compartment during Schistosoma mansoni infection.

Fairfax KC, Everts B, Smith AM, Pearce EJ.

J Immunol. 2013 Oct 15;191(8):4202-10. doi: 10.4049/jimmunol.1301357. Epub 2013 Sep 13.

24.

The TACI receptor regulates T-cell-independent marginal zone B cell responses through innate activation-induced cell death.

Figgett WA, Fairfax K, Vincent FB, Le Page MA, Katik I, Deliyanti D, Quah PS, Verma P, Grumont R, Gerondakis S, Hertzog P, O'Reilly LA, Strasser A, Mackay F.

Immunity. 2013 Sep 19;39(3):573-83. doi: 10.1016/j.immuni.2013.05.019. Epub 2013 Sep 5.

25.

The BAFF/APRIL system: emerging functions beyond B cell biology and autoimmunity.

Vincent FB, Saulep-Easton D, Figgett WA, Fairfax KA, Mackay F.

Cytokine Growth Factor Rev. 2013 Jun;24(3):203-15. doi: 10.1016/j.cytogfr.2013.04.003. Epub 2013 May 15. Review.

PMID:
23684423
26.

Mcl-1 is essential for the survival of plasma cells.

Peperzak V, Vikström I, Walker J, Glaser SP, LePage M, Coquery CM, Erickson LD, Fairfax K, Mackay F, Strasser A, Nutt SL, Tarlinton DM.

Nat Immunol. 2013 Mar;14(3):290-7. doi: 10.1038/ni.2527. Epub 2013 Feb 3. Erratum in: Nat Immunol. 2013 Aug;14(8):877.

27.

Th2 responses in schistosomiasis.

Fairfax K, Nascimento M, Huang SC, Everts B, Pearce EJ.

Semin Immunopathol. 2012 Nov;34(6):863-71. doi: 10.1007/s00281-012-0354-4. Epub 2012 Nov 9. Review.

PMID:
23139101
28.

BAFF/BLyS inhibitors: A new prospect for treatment of systemic lupus erythematosus.

Fairfax K, Mackay IR, Mackay F.

IUBMB Life. 2012 Jul;64(7):595-602. doi: 10.1002/iub.1046. Epub 2012 May 29. Review.

29.

IL-10R blockade during chronic schistosomiasis mansoni results in the loss of B cells from the liver and the development of severe pulmonary disease.

Fairfax KC, Amiel E, King IL, Freitas TC, Mohrs M, Pearce EJ.

PLoS Pathog. 2012 Jan;8(1):e1002490. doi: 10.1371/journal.ppat.1002490. Epub 2012 Jan 26.

30.

Targeting malignant B cells as antigen-presenting cells: TLR-9 agonist induces systemic regression of lymphoma.

Klein-González N, Holtick U, Fairfax K, Weihrauch MR, von Bergwelt-Baildon MS.

Expert Rev Vaccines. 2011 Mar;10(3):295-8. doi: 10.1586/erv.11.6.

PMID:
21434797
31.

Signaling pathways in T follicular helper cells.

Rolf J, Fairfax K, Turner M.

J Immunol. 2010 Jun 15;184(12):6563-8. doi: 10.4049/jimmunol.1000202. Review.

32.

Individual and overlapping roles of BH3-only proteins Bim and Bad in apoptosis of lymphocytes and platelets and in suppression of thymic lymphoma development.

Kelly PN, White MJ, Goschnick MW, Fairfax KA, Tarlinton DM, Kinkel SA, Bouillet P, Adams JM, Kile BT, Strasser A.

Cell Death Differ. 2010 Oct;17(10):1655-64. doi: 10.1038/cdd.2010.43. Epub 2010 Apr 30.

33.

Characterisation of a fatty acid and retinol binding protein orthologue from the hookworm Ancylostoma ceylanicum.

Fairfax KC, Vermeire JJ, Harrison LM, Bungiro RD, Grant W, Husain SZ, Cappello M.

Int J Parasitol. 2009 Dec;39(14):1561-71. doi: 10.1016/j.ijpara.2009.06.005. Epub 2009 Jul 8.

34.

Plasma cell development: from B-cell subsets to long-term survival niches.

Fairfax KA, Kallies A, Nutt SL, Tarlinton DM.

Semin Immunol. 2008 Feb;20(1):49-58. doi: 10.1016/j.smim.2007.12.002. Epub 2008 Jan 28. Review.

PMID:
18222702
35.

BLIMP1 guides the fate of effector B and T cells.

Nutt SL, Fairfax KA, Kallies A.

Nat Rev Immunol. 2007 Dec;7(12):923-7. Review.

PMID:
17965637
36.

Initiation of plasma-cell differentiation is independent of the transcription factor Blimp-1.

Kallies A, Hasbold J, Fairfax K, Pridans C, Emslie D, McKenzie BS, Lew AM, Corcoran LM, Hodgkin PD, Tarlinton DM, Nutt SL.

Immunity. 2007 May;26(5):555-66.

37.

NK cell maturation and peripheral homeostasis is associated with KLRG1 up-regulation.

Huntington ND, Tabarias H, Fairfax K, Brady J, Hayakawa Y, Degli-Esposti MA, Smyth MJ, Tarlinton DM, Nutt SL.

J Immunol. 2007 Apr 15;178(8):4764-70.

38.

Different kinetics of blimp-1 induction in B cell subsets revealed by reporter gene.

Fairfax KA, Corcoran LM, Pridans C, Huntington ND, Kallies A, Nutt SL, Tarlinton DM.

J Immunol. 2007 Apr 1;178(7):4104-11.

39.

FcgammaRIIb controls bone marrow plasma cell persistence and apoptosis.

Xiang Z, Cutler AJ, Brownlie RJ, Fairfax K, Lawlor KE, Severinson E, Walker EU, Manz RA, Tarlinton DM, Smith KG.

Nat Immunol. 2007 Apr;8(4):419-29. Epub 2007 Feb 18.

PMID:
17322888
40.

The type III effector repertoire of Pseudomonas syringae pv. syringae B728a and its role in survival and disease on host and non-host plants.

Vinatzer BA, Teitzel GM, Lee MW, Jelenska J, Hotton S, Fairfax K, Jenrette J, Greenberg JT.

Mol Microbiol. 2006 Oct;62(1):26-44. Epub 2006 Aug 30.

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