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Items: 1 to 50 of 70

1.

Retinoic acid signaling reduction recapitulates the effects of alcohol on embryo size.

Shukrun N, Shabtai Y, Pillemer G, Fainsod A.

Genesis. 2019 Jul;57(7-8):e23284. doi: 10.1002/dvg.23284. Epub 2019 Feb 6.

PMID:
30672660
2.

Insights into retinoic acid deficiency and the induction of craniofacial malformations and microcephaly in fetal alcohol spectrum disorder.

Petrelli B, Bendelac L, Hicks GG, Fainsod A.

Genesis. 2019 Jan;57(1):e23278. doi: 10.1002/dvg.23278. Epub 2019 Jan 21. Review.

PMID:
30614633
3.

Special issue on fetal alcohol spectrum disorder.

Fainsod A, Hicks G.

Biochem Cell Biol. 2018 Apr;96(2):v-vi. doi: 10.1139/bcb-2018-0087. Epub 2018 Apr 10. No abstract available.

PMID:
29634293
4.

ADMP controls the size of Spemann's organizer through a network of self-regulating expansion-restriction signals.

Leibovich A, Kot-Leibovich H, Ben-Zvi D, Fainsod A.

BMC Biol. 2018 Jan 22;16(1):13. doi: 10.1186/s12915-018-0483-x.

5.

Acetaldehyde inhibits retinoic acid biosynthesis to mediate alcohol teratogenicity.

Shabtai Y, Bendelac L, Jubran H, Hirschberg J, Fainsod A.

Sci Rep. 2018 Jan 10;8(1):347. doi: 10.1038/s41598-017-18719-7.

6.

Xenopus embryos to study fetal alcohol syndrome, a model for environmental teratogenesis.

Fainsod A, Kot-Leibovich H.

Biochem Cell Biol. 2018 Apr;96(2):77-87. doi: 10.1139/bcb-2017-0219. Epub 2017 Oct 25.

PMID:
29069552
7.

Competition between ethanol clearance and retinoic acid biosynthesis in the induction of fetal alcohol syndrome.

Shabtai Y, Fainsod A.

Biochem Cell Biol. 2018 Apr;96(2):148-160. doi: 10.1139/bcb-2017-0132. Epub 2017 Oct 5. Review.

PMID:
28982012
8.

Expression of the ALK1 family of type I BMP/ADMP receptors during gastrula stages in Xenopus embryos.

Leibovich A, Steinbeißer H, Fainsod A.

Int J Dev Biol. 2017;61(6-7):465-470. doi: 10.1387/ijdb.170037af.

9.

ADHFe1: a novel enzyme involved in retinoic acid-dependent Hox activation.

Shabtai Y, Shukrun N, Fainsod A.

Int J Dev Biol. 2017;61(3-4-5):303-310. doi: 10.1387/ijdb.160252af.

10.

Roles of the cilium-associated gene CCDC11 in left-right patterning and in laterality disorders in humans.

Gur M, Cohen EB, Genin O, Fainsod A, Perles Z, Cinnamon Y.

Int J Dev Biol. 2017;61(3-4-5):267-276. doi: 10.1387/ijdb.160442yc.

11.

A novel role of the organizer gene Goosecoid as an inhibitor of Wnt/PCP-mediated convergent extension in Xenopus and mouse.

Ulmer B, Tingler M, Kurz S, Maerker M, Andre P, Mönch D, Campione M, Deißler K, Lewandoski M, Thumberger T, Schweickert A, Fainsod A, Steinbeißer H, Blum M.

Sci Rep. 2017 Feb 21;7:43010. doi: 10.1038/srep43010.

12.

Kinetic characterization and regulation of the human retinaldehyde dehydrogenase 2 enzyme during production of retinoic acid.

Shabtai Y, Jubran H, Nassar T, Hirschberg J, Fainsod A.

Biochem J. 2016 May 15;473(10):1423-31. doi: 10.1042/BCJ20160101. Epub 2016 Mar 21.

PMID:
27001866
13.

Xenopus Pkdcc1 and Pkdcc2 Are Two New Tyrosine Kinases Involved in the Regulation of JNK Dependent Wnt/PCP Signaling Pathway.

Vitorino M, Silva AC, Inácio JM, Ramalho JS, Gur M, Fainsod A, Steinbeisser H, Belo JA.

PLoS One. 2015 Aug 13;10(8):e0135504. doi: 10.1371/journal.pone.0135504. eCollection 2015.

14.

Phosphorylation-mediated stabilization of Bora in mitosis coordinates Plx1/Plk1 and Cdk1 oscillations.

Feine O, Hukasova E, Bruinsma W, Freire R, Fainsod A, Gannon J, Mahbubani HM, Lindqvist A, Brandeis M.

Cell Cycle. 2014;13(11):1727-36. doi: 10.4161/cc.28630. Epub 2014 Mar 26.

15.

Scaling of dorsal-ventral patterning in the Xenopus laevis embryo.

Ben-Zvi D, Fainsod A, Shilo BZ, Barkai N.

Bioessays. 2014 Feb;36(2):151-6. doi: 10.1002/bies.201300136. Epub 2013 Dec 9.

PMID:
24323952
16.

Cdx1 is essential for the initiation of HoxC8 expression during early embryogenesis.

Schyr RB, Shabtai Y, Shashikant CS, Fainsod A.

FASEB J. 2012 Jun;26(6):2674-84. doi: 10.1096/fj.11-191403. Epub 2012 Mar 16.

PMID:
22426122
17.

Negative autoregulation of Oct3/4 through Cdx1 promotes the onset of gastrulation.

Rousso SZ, Schyr RB, Gur M, Zouela N, Kot-Leibovich H, Shabtai Y, Koutsi-Urshanski N, Baldessari D, Pillemer G, Niehrs C, Fainsod A.

Dev Dyn. 2011 Apr;240(4):796-807. doi: 10.1002/dvdy.22588. Epub 2011 Feb 28.

18.

Molecular and functional characterizations of gastrula organizer cells derived from human embryonic stem cells.

Sharon N, Mor I, Golan-lev T, Fainsod A, Benvenisty N.

Stem Cells. 2011 Apr;29(4):600-8. doi: 10.1002/stem.621.

19.

Oct-3/4 regulates stem cell identity and cell fate decisions by modulating Wnt/β-catenin signalling.

Abu-Remaileh M, Gerson A, Farago M, Nathan G, Alkalay I, Zins Rousso S, Gur M, Fainsod A, Bergman Y.

EMBO J. 2010 Oct 6;29(19):3236-48. doi: 10.1038/emboj.2010.200. Epub 2010 Aug 24.

20.

Ethanol induces embryonic malformations by competing for retinaldehyde dehydrogenase activity during vertebrate gastrulation.

Kot-Leibovich H, Fainsod A.

Dis Model Mech. 2009 May-Jun;2(5-6):295-305. doi: 10.1242/dmm.001420. Epub 2009 Apr 6.

21.

Scaling of the BMP activation gradient in Xenopus embryos.

Ben-Zvi D, Shilo BZ, Fainsod A, Barkai N.

Nature. 2008 Jun 26;453(7199):1205-11. doi: 10.1038/nature07059.

PMID:
18580943
22.

Early molecular effects of ethanol during vertebrate embryogenesis.

Yelin R, Kot H, Yelin D, Fainsod A.

Differentiation. 2007 Jun;75(5):393-403. Epub 2007 Feb 5.

PMID:
17286601
23.
24.

Ethanol exposure affects gene expression in the embryonic organizer and reduces retinoic acid levels.

Yelin R, Schyr RB, Kot H, Zins S, Frumkin A, Pillemer G, Fainsod A.

Dev Biol. 2005 Mar 1;279(1):193-204.

25.

BMP controls nitric oxide-mediated regulation of cell numbers in the developing neural tube.

Traister A, Abashidze S, Gold V, Yairi R, Michael E, Plachta N, McKinnell I, Patel K, Fainsod A, Weil M.

Cell Death Differ. 2004 Aug;11(8):832-41.

26.

The RNA-binding protein Vg1 RBP is required for cell migration during early neural development.

Yaniv K, Fainsod A, Kalcheim C, Yisraeli JK.

Development. 2003 Dec;130(23):5649-61. Epub 2003 Oct 1.

27.

Methylation of HoxA5 and HoxB5 and its relevance to expression during mouse development.

Hershko AY, Kafri T, Fainsod A, Razin A.

Gene. 2003 Jan 2;302(1-2):65-72.

PMID:
12527197
28.

The competence of marginal zone cells to become Spemann's organizer is controlled by Xcad2.

Levy V, Marom K, Zins S, Koutsia N, Yelin R, Fainsod A.

Dev Biol. 2002 Aug 1;248(1):40-51.

29.

Gbx2 interacts with Otx2 and patterns the anterior-posterior axis during gastrulation in Xenopus.

Tour E, Pillemer G, Gruenbaum Y, Fainsod A.

Mech Dev. 2002 Mar;112(1-2):141-51.

30.

Otx2 can activate the isthmic organizer genetic network in the Xenopus embryo.

Tour E, Pillemer G, Gruenbaum Y, Fainsod A.

Mech Dev. 2002 Jan;110(1-2):3-13.

31.

The two Xenopus Gbx2 genes exhibit similar, but not identical expression patterns and can affect head formation.

Tour E, Pillemer G, Gruenbaum Y, Fainsod A.

FEBS Lett. 2001 Oct 26;507(2):205-9.

32.
33.

Patterning of the mesoderm involves several threshold responses to BMP-4 and Xwnt-8.

Marom K, Fainsod A, Steinbeisser H.

Mech Dev. 1999 Sep;87(1-2):33-44.

34.

A role for the homeobox gene Xvex-1 as part of the BMP-4 ventral signaling pathway.

Shapira E, Marom K, Yelin R, Levy A, Fainsod A.

Mech Dev. 1999 Aug;86(1-2):99-111.

35.

The Xcad-2 gene can provide a ventral signal independent of BMP-4.

Pillemer G, Yelin R, Epstein M, Gont L, Frumkin Y, Yisraeli JK, Steinbeisser H, Fainsod A.

Mech Dev. 1998 Jun;74(1-2):133-43.

36.

Nested expression and sequential downregulation of the Xenopus caudal genes along the anterior-posterior axis.

Pillemer G, Epstein M, Blumberg B, Yisraeli JK, De Robertis EM, Steinbeisser H, Fainsod A.

Mech Dev. 1998 Feb;71(1-2):193-6.

37.

Patterning of the embryo along the anterior-posterior axis: the role of the caudal genes.

Epstein M, Pillemer G, Yelin R, Yisraeli JK, Fainsod A.

Development. 1997 Oct;124(19):3805-14.

39.

The dorsalizing and neural inducing gene follistatin is an antagonist of BMP-4.

Fainsod A, Deissler K, Yelin R, Marom K, Epstein M, Pillemer G, Steinbeisser H, Blum M.

Mech Dev. 1997 Apr;63(1):39-50.

40.

Overexpression of the homeobox gene Xnot-2 leads to notochord formation in Xenopus.

Gont LK, Fainsod A, Kim SH, De Robertis EM.

Dev Biol. 1996 Feb 25;174(1):174-8.

41.

The role of gsc and BMP-4 in dorsal-ventral patterning of the marginal zone in Xenopus: a loss-of-function study using antisense RNA.

Steinbeisser H, Fainsod A, Niehrs C, Sasai Y, De Robertis EM.

EMBO J. 1995 Nov 1;14(21):5230-43.

42.

Mapping the CdxA gene to a new linkage group in chicken.

Khatib H, Berkovitz D, Ratz T, Plotzki Y, Fainsod A, Gruenbaum Y.

Anim Genet. 1995 Jun;26(3):211. No abstract available.

PMID:
7793703
43.

Expression of the novel murine homeobox gene Sax-1 in the developing nervous system.

Schubert FR, Fainsod A, Gruenbaum Y, Gruss P.

Mech Dev. 1995 May;51(1):99-114.

44.

On the function of BMP-4 in patterning the marginal zone of the Xenopus embryo.

Fainsod A, Steinbeisser H, De Robertis EM.

EMBO J. 1994 Nov 1;13(21):5015-25.

45.

The spatial and temporal dynamics of Sax1 (CHox3) homeobox gene expression in the chick's spinal cord.

Spann P, Ginsburg M, Rangini Z, Fainsod A, Eyal-Giladi H, Gruenbaum Y.

Development. 1994 Jul;120(7):1817-28.

46.

A role for CdxA in gut closure and intestinal epithelia differentiation.

Frumkin A, Pillemer G, Haffner R, Tarcic N, Gruenbaum Y, Fainsod A.

Development. 1994 Feb;120(2):253-63.

47.

The evolution of vertebrate gastrulation.

De Robertis EM, Fainsod A, Gont LK, Steinbeisser H.

Dev Suppl. 1994:117-24.

PMID:
7579512
48.

Isolation and characterization of target sequences of the chicken CdxA homeobox gene.

Margalit Y, Yarus S, Shapira E, Gruenbaum Y, Fainsod A.

Nucleic Acids Res. 1993 Oct 25;21(21):4915-22.

49.

The chicken CdxA homeobox gene and axial positioning during gastrulation.

Frumkin A, Haffner R, Shapira E, Tarcic N, Gruenbaum Y, Fainsod A.

Development. 1993 Jun;118(2):553-62.

50.

CHox E, a chicken homeogene of the H2.0 type exhibits dorso-ventral restriction in the proliferating region of the spinal cord.

Rangini Z, Ben-Yehuda A, Shapira E, Gruenbaum Y, Fainsod A.

Mech Dev. 1991 Aug;35(1):13-24.

PMID:
1683253

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