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Items: 22


Association between plasma diacetylspermine and tumor spermine synthase with outcome in triple negative breast cancer.

Fahrmann JF, Vykoukal J, Fleury A, Tripathi S, Dennison JB, Murage E, Wang P, Yu CY, Capello M, Creighton CJ, Do KA, Long JP, Irajizad E, Peterson C, Katayama H, Disis ML, Arun B, Hanash S.

J Natl Cancer Inst. 2019 Sep 10. pii: djz182. doi: 10.1093/jnci/djz182. [Epub ahead of print]


Time-resolved decoding of metabolic signatures of in vitro growth of the hemibiotrophic pathogen Colletotrichum sublineolum.

Tugizimana F, Djami-Tchatchou AT, Fahrmann JF, Steenkamp PA, Piater LA, Dubery IA.

Sci Rep. 2019 Mar 1;9(1):3290. doi: 10.1038/s41598-019-38692-7.


A Plasma-Derived Protein-Metabolite Multiplexed Panel for Early-Stage Pancreatic Cancer.

Fahrmann JF, Bantis LE, Capello M, Scelo G, Dennison JB, Patel N, Murage E, Vykoukal J, Kundnani DL, Foretova L, Fabianova E, Holcatova I, Janout V, Feng Z, Yip-Schneider M, Zhang J, Brand R, Taguchi A, Maitra A, Brennan P, Max Schmidt C, Hanash S.

J Natl Cancer Inst. 2019 Apr 1;111(4):372-379. doi: 10.1093/jnci/djy126.


Umbilical cord blood metabolomics reveal distinct signatures of dyslipidemia prior to bronchopulmonary dysplasia and pulmonary hypertension.

La Frano MR, Fahrmann JF, Grapov D, Pedersen TL, Newman JW, Fiehn O, Underwood MA, Mestan K, Steinhorn RH, Wedgwood S.

Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L870-L881. doi: 10.1152/ajplung.00283.2017. Epub 2018 Aug 16.


Blood based biomarkers beyond genomics for lung cancer screening.

Hanash SM, Ostrin EJ, Fahrmann JF.

Transl Lung Cancer Res. 2018 Jun;7(3):327-335. doi: 10.21037/tlcr.2018.05.13. Review.


JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance.

Wang T, Fahrmann JF, Lee H, Li YJ, Tripathi SC, Yue C, Zhang C, Lifshitz V, Song J, Yuan Y, Somlo G, Jandial R, Ann D, Hanash S, Jove R, Yu H.

Cell Metab. 2018 Jun 5;27(6):1357. doi: 10.1016/j.cmet.2018.04.018. No abstract available.


JAK/STAT3-Regulated Fatty Acid β-Oxidation Is Critical for Breast Cancer Stem Cell Self-Renewal and Chemoresistance.

Wang T, Fahrmann JF, Lee H, Li YJ, Tripathi SC, Yue C, Zhang C, Lifshitz V, Song J, Yuan Y, Somlo G, Jandial R, Ann D, Hanash S, Jove R, Yu H.

Cell Metab. 2018 Jan 9;27(1):136-150.e5. doi: 10.1016/j.cmet.2017.11.001. Epub 2017 Dec 14. Erratum in: Cell Metab. 2018 Jun 5;27(6):1357.


Plasma-derived extracellular vesicle proteins as a source of biomarkers for lung adenocarcinoma.

Vykoukal J, Sun N, Aguilar-Bonavides C, Katayama H, Tanaka I, Fahrmann JF, Capello M, Fujimoto J, Aguilar M, Wistuba II, Taguchi A, Ostrin EJ, Hanash SM.

Oncotarget. 2017 Sep 8;8(56):95466-95480. doi: 10.18632/oncotarget.20748. eCollection 2017 Nov 10.


MCAM Mediates Chemoresistance in Small-Cell Lung Cancer via the PI3K/AKT/SOX2 Signaling Pathway.

Tripathi SC, Fahrmann JF, Celiktas M, Aguilar M, Marini KD, Jolly MK, Katayama H, Wang H, Murage EN, Dennison JB, Watkins DN, Levine H, Ostrin EJ, Taguchi A, Hanash SM.

Cancer Res. 2017 Aug 15;77(16):4414-4425. doi: 10.1158/0008-5472.CAN-16-2874. Epub 2017 Jun 23.


Review of emerging metabolomic tools and resources: 2015-2016.

Misra BB, Fahrmann JF, Grapov D.

Electrophoresis. 2017 Sep;38(18):2257-2274. doi: 10.1002/elps.201700110. Epub 2017 Aug 1. Review.


Role of CPS1 in Cell Growth, Metabolism and Prognosis in LKB1-Inactivated Lung Adenocarcinoma.

Çeliktas M, Tanaka I, Tripathi SC, Fahrmann JF, Aguilar-Bonavides C, Villalobos P, Delgado O, Dhillon D, Dennison JB, Ostrin EJ, Wang H, Behrens C, Do KA, Gazdar AF, Hanash SM, Taguchi A.

J Natl Cancer Inst. 2017 Mar 1;109(3):1-9. doi: 10.1093/jnci/djw231.


Mass Spectral Feature List Optimizer (MS-FLO): A Tool To Minimize False Positive Peak Reports in Untargeted Liquid Chromatography-Mass Spectroscopy (LC-MS) Data Processing.

DeFelice BC, Mehta SS, Samra S, Čajka T, Wancewicz B, Fahrmann JF, Fiehn O.

Anal Chem. 2017 Mar 21;89(6):3250-3255. doi: 10.1021/acs.analchem.6b04372. Epub 2017 Mar 6.


Integrated Metabolomics and Proteomics Highlight Altered Nicotinamide- and Polyamine Pathways in Lung Adenocarcinoma.

Fahrmann JF, Grapov DD, Wanichthanarak K, DeFelice BC, Salemi MR, Rom WN, Gandara DR, Phinney BS, Fiehn O, Pass H, Miyamoto S.

Carcinogenesis. 2017 Jan 3. pii: bgw205. doi: 10.1093/carcin/bgw205. [Epub ahead of print] Review.


Proteomic profiling of lung adenocarcinoma indicates heightened DNA repair, antioxidant mechanisms and identifies LASP1 as a potential negative predictor of survival.

Fahrmann JF, Grapov D, Phinney BS, Stroble C, DeFelice BC, Rom W, Gandara DR, Zhang Y, Fiehn O, Pass H, Miyamoto S.

Clin Proteomics. 2016 Oct 27;13:31. doi: 10.1186/s12014-016-9132-y. eCollection 2016.


Serum phosphatidylethanolamine levels distinguish benign from malignant solitary pulmonary nodules and represent a potential diagnostic biomarker for lung cancer.

Fahrmann JF, Grapov D, DeFelice BC, Taylor S, Kim K, Kelly K, Wikoff WR, Pass H, Rom WN, Fiehn O, Miyamoto S.

Cancer Biomark. 2016 Mar 11;16(4):609-17. doi: 10.3233/CBM-160602.


An in silico MS/MS library for automatic annotation of novel FAHFA lipids.

Ma Y, Kind T, Vaniya A, Gennity I, Fahrmann JF, Fiehn O.

J Cheminform. 2015 Nov 16;7:53. doi: 10.1186/s13321-015-0104-4. eCollection 2015.


Genomic, Proteomic, and Metabolomic Data Integration Strategies.

Wanichthanarak K, Fahrmann JF, Grapov D.

Biomark Insights. 2015 Sep 7;10(Suppl 4):1-6. doi: 10.4137/BMI.S29511. eCollection 2015. Review.


Investigation of metabolomic blood biomarkers for detection of adenocarcinoma lung cancer.

Fahrmann JF, Kim K, DeFelice BC, Taylor SL, Gandara DR, Yoneda KY, Cooke DT, Fiehn O, Kelly K, Miyamoto S.

Cancer Epidemiol Biomarkers Prev. 2015 Nov;24(11):1716-23. doi: 10.1158/1055-9965.EPI-15-0427. Epub 2015 Aug 17.


Metabolomics and transcriptomics identify pathway differences between visceral and subcutaneous adipose tissue in colorectal cancer patients: the ColoCare study.

Liesenfeld DB, Grapov D, Fahrmann JF, Salou M, Scherer D, Toth R, Habermann N, Böhm J, Schrotz-King P, Gigic B, Schneider M, Ulrich A, Herpel E, Schirmacher P, Fiehn O, Lampe JW, Ulrich CM.

Am J Clin Nutr. 2015 Aug;102(2):433-43. doi: 10.3945/ajcn.114.103804. Epub 2015 Jul 8.


Metabolomic markers of altered nucleotide metabolism in early stage adenocarcinoma.

Wikoff WR, Grapov D, Fahrmann JF, DeFelice B, Rom WN, Pass HI, Kim K, Nguyen U, Taylor SL, Gandara DR, Kelly K, Fiehn O, Miyamoto S.

Cancer Prev Res (Phila). 2015 May;8(5):410-8. doi: 10.1158/1940-6207.CAPR-14-0329. Epub 2015 Feb 5.


Inhibition of nuclear factor kappa B activation in early-stage chronic lymphocytic leukemia by omega-3 fatty acids.

Fahrmann JF, Ballester OF, Ballester G, Witte TR, Salazar AJ, Kordusky B, Cowen KG, Ion G, Primerano DA, Boskovic G, Denvir J, Hardman WE.

Cancer Invest. 2013 Jan;31(1):24-38. doi: 10.3109/07357907.2012.743553. Epub 2012 Nov 29.


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