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Items: 1 to 50 of 60

1.

NUP214 in Leukemia: It's More than Transport.

Mendes A, Fahrenkrog B.

Cells. 2019 Jan 21;8(1). pii: E76. doi: 10.3390/cells8010076. Review.

2.

Biallelic mutations in nucleoporin NUP88 cause lethal fetal akinesia deformation sequence.

Bonnin E, Cabochette P, Filosa A, Jühlen R, Komatsuzaki S, Hezwani M, Dickmanns A, Martinelli V, Vermeersch M, Supply L, Martins N, Pirenne L, Ravenscroft G, Lombard M, Port S, Spillner C, Janssens S, Roets E, Van Dorpe J, Lammens M, Kehlenbach RH, Ficner R, Laing NG, Hoffmann K, Vanhollebeke B, Fahrenkrog B.

PLoS Genet. 2018 Dec 13;14(12):e1007845. doi: 10.1371/journal.pgen.1007845. eCollection 2018 Dec.

3.

Perturbations in Traffic: Aberrant Nucleocytoplasmic Transport at the Heart of Neurodegeneration.

Fahrenkrog B, Harel A.

Cells. 2018 Nov 26;7(12). pii: E232. doi: 10.3390/cells7120232.

4.

Moonlighting nuclear pore proteins: tissue-specific nucleoporin function in health and disease.

Jühlen R, Fahrenkrog B.

Histochem Cell Biol. 2018 Dec;150(6):593-605. doi: 10.1007/s00418-018-1748-8. Epub 2018 Oct 25. Review.

PMID:
30361777
5.

Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing.

Shoaib M, Walter D, Gillespie PJ, Izard F, Fahrenkrog B, Lleres D, Lerdrup M, Johansen JV, Hansen K, Julien E, Blow JJ, Sørensen CS.

Nat Commun. 2018 Sep 12;9(1):3704. doi: 10.1038/s41467-018-06066-8.

6.

Guidelines and recommendations on yeast cell death nomenclature.

Carmona-Gutierrez D, Bauer MA, Zimmermann A, Aguilera A, Austriaco N, Ayscough K, Balzan R, Bar-Nun S, Barrientos A, Belenky P, Blondel M, Braun RJ, Breitenbach M, Burhans WC, Büttner S, Cavalieri D, Chang M, Cooper KF, Côrte-Real M, Costa V, Cullin C, Dawes I, Dengjel J, Dickman MB, Eisenberg T, Fahrenkrog B, Fasel N, Fröhlich KU, Gargouri A, Giannattasio S, Goffrini P, Gourlay CW, Grant CM, Greenwood MT, Guaragnella N, Heger T, Heinisch J, Herker E, Herrmann JM, Hofer S, Jiménez-Ruiz A, Jungwirth H, Kainz K, Kontoyiannis DP, Ludovico P, Manon S, Martegani E, Mazzoni C, Megeney LA, Meisinger C, Nielsen J, Nyström T, Osiewacz HD, Outeiro TF, Park HO, Pendl T, Petranovic D, Picot S, Polčic P, Powers T, Ramsdale M, Rinnerthaler M, Rockenfeller P, Ruckenstuhl C, Schaffrath R, Segovia M, Severin FF, Sharon A, Sigrist SJ, Sommer-Ruck C, Sousa MJ, Thevelein JM, Thevissen K, Titorenko V, Toledano MB, Tuite M, Vögtle FN, Westermann B, Winderickx J, Wissing S, Wölfl S, Zhang ZJ, Zhao RY, Zhou B, Galluzzi L, Kroemer G, Madeo F.

Microb Cell. 2018 Jan 1;5(1):4-31. doi: 10.15698/mic2018.01.607. Review.

7.

Localisation of Nup153 and SENP1 to nuclear pore complexes is required for 53BP1-mediated DNA double-strand break repair.

Duheron V, Nilles N, Pecenko S, Martinelli V, Fahrenkrog B.

J Cell Sci. 2017 Jul 15;130(14):2306-2316. doi: 10.1242/jcs.198390. Epub 2017 Jun 2.

8.

The functional versatility of the nuclear pore complex proteins.

Hezwani M, Fahrenkrog B.

Semin Cell Dev Biol. 2017 Aug;68:2-9. doi: 10.1016/j.semcdb.2017.05.004. Epub 2017 May 12. Review.

PMID:
28506894
9.

Taking a Bad Turn: Compromised DNA Damage Response in Leukemia.

Nilles N, Fahrenkrog B.

Cells. 2017 May 4;6(2). pii: E11. doi: 10.3390/cells6020011. Review.

10.

The Oncogenic Fusion Proteins SET-Nup214 and Sequestosome-1 (SQSTM1)-Nup214 Form Dynamic Nuclear Bodies and Differentially Affect Nuclear Protein and Poly(A)+ RNA Export.

Port SA, Mendes A, Valkova C, Spillner C, Fahrenkrog B, Kaether C, Kehlenbach RH.

J Biol Chem. 2016 Oct 28;291(44):23068-23083. Epub 2016 Sep 9.

11.

Expression of Leukemia-Associated Nup98 Fusion Proteins Generates an Aberrant Nuclear Envelope Phenotype.

Fahrenkrog B, Martinelli V, Nilles N, Fruhmann G, Chatel G, Juge S, Sauder U, Di Giacomo D, Mecucci C, Schwaller J.

PLoS One. 2016 Mar 31;11(3):e0152321. doi: 10.1371/journal.pone.0152321. eCollection 2016.

12.

Histone modifications as regulators of life and death in Saccharomyces cerevisiae.

Fahrenkrog B.

Microb Cell. 2015 Dec 31;3(1):1-13. doi: 10.15698/mic2016.01.472. Review.

13.

Nuclear Pore Complexes and Nucleocytoplasmic Transport: From Structure to Function to Disease.

Dickmanns A, Kehlenbach RH, Fahrenkrog B.

Int Rev Cell Mol Biol. 2015;320:171-233. doi: 10.1016/bs.ircmb.2015.07.010. Epub 2015 Aug 19. Review.

PMID:
26614874
14.

Complex Commingling: Nucleoporins and the Spindle Assembly Checkpoint.

Mossaid I, Fahrenkrog B.

Cells. 2015 Nov 3;4(4):706-25. doi: 10.3390/cells4040706. Review.

15.

Structural characterization of altered nucleoporin Nup153 expression in human cells by thin-section electron microscopy.

Duheron V, Chatel G, Sauder U, Oliveri V, Fahrenkrog B.

Nucleus. 2014;5(6):601-12. doi: 10.4161/19491034.2014.990853.

16.

Exploring nuclear pore complex molecular architecture by immuno-electron microscopy using Xenopus oocytes.

Panté N, Fahrenkrog B.

Methods Cell Biol. 2014;122:81-98. doi: 10.1016/B978-0-12-417160-2.00004-7.

PMID:
24857726
17.

Loss of histone H3 methylation at lysine 4 triggers apoptosis in Saccharomyces cerevisiae.

Walter D, Matter A, Fahrenkrog B.

PLoS Genet. 2014 Jan 30;10(1):e1004095. doi: 10.1371/journal.pgen.1004095. eCollection 2014 Jan.

18.

Dynamics and diverse functions of nuclear pore complex proteins.

Chatel G, Fahrenkrog B.

Nucleus. 2012 Mar 1;3(2):162-71. doi: 10.4161/nucl.19674. Epub 2012 Mar 1. Review.

19.

Early parenteral nutrition evokes a phenotype of autophagy deficiency in liver and skeletal muscle of critically ill rabbits.

Derde S, Vanhorebeek I, Güiza F, Derese I, Gunst J, Fahrenkrog B, Martinet W, Vervenne H, Ververs EJ, Larsson L, Van den Berghe G.

Endocrinology. 2012 May;153(5):2267-76. doi: 10.1210/en.2011-2068. Epub 2012 Mar 6.

PMID:
22396453
20.

Domain topology of nucleoporin Nup98 within the nuclear pore complex.

Chatel G, Desai SH, Mattheyses AL, Powers MA, Fahrenkrog B.

J Struct Biol. 2012 Jan;177(1):81-9. doi: 10.1016/j.jsb.2011.11.004. Epub 2011 Nov 12.

21.

Distinct association of the nuclear pore protein Nup153 with A- and B-type lamins.

Al-Haboubi T, Shumaker DK, Köser J, Wehnert M, Fahrenkrog B.

Nucleus. 2011 Sep-Oct;2(5):500-9. doi: 10.4161/nucl.2.5.17913. Epub 2011 Sep 1.

PMID:
21983083
22.

Nma111p, the pro-apoptotic HtrA-like nuclear serine protease in Saccharomyces cerevisiae: a short survey.

Fahrenkrog B.

Biochem Soc Trans. 2011 Oct;39(5):1499-501. doi: 10.1042/BST0391499. Review.

PMID:
21936841
23.

Nucleoporins: leaving the nuclear pore complex for a successful mitosis.

Chatel G, Fahrenkrog B.

Cell Signal. 2011 Oct;23(10):1555-62. doi: 10.1016/j.cellsig.2011.05.023. Epub 2011 Jun 13. Review.

PMID:
21683138
24.

The nucleoporin Nup153 affects spindle checkpoint activity due to an association with Mad1.

Lussi YC, Shumaker DK, Shimi T, Fahrenkrog B.

Nucleus. 2010 Jan-Feb;1(1):71-84. doi: 10.4161/nucl.1.1.10244.

25.

The nucleoporin Nup88 is interacting with nuclear lamin A.

Lussi YC, Hügi I, Laurell E, Kutay U, Fahrenkrog B.

Mol Biol Cell. 2011 Apr;22(7):1080-90. doi: 10.1091/mbc.E10-05-0463. Epub 2011 Feb 2.

26.

Bre1p-mediated histone H2B ubiquitylation regulates apoptosis in Saccharomyces cerevisiae.

Walter D, Matter A, Fahrenkrog B.

J Cell Sci. 2010 Jun 1;123(Pt 11):1931-9. doi: 10.1242/jcs.065938. Epub 2010 May 11.

27.

Nuclear localisation is crucial for the proapoptotic activity of the HtrA-like serine protease Nma111p.

Belanger KD, Walter D, Henderson TA, Yelton AL, O'Brien TG, Belanger KG, Geier SJ, Fahrenkrog B.

J Cell Sci. 2009 Nov 1;122(Pt 21):3931-41. doi: 10.1242/jcs.056887. Epub 2009 Oct 6.

28.

Induction of autophagy by spermidine promotes longevity.

Eisenberg T, Knauer H, Schauer A, Büttner S, Ruckenstuhl C, Carmona-Gutierrez D, Ring J, Schroeder S, Magnes C, Antonacci L, Fussi H, Deszcz L, Hartl R, Schraml E, Criollo A, Megalou E, Weiskopf D, Laun P, Heeren G, Breitenbach M, Grubeck-Loebenstein B, Herker E, Fahrenkrog B, Fröhlich KU, Sinner F, Tavernarakis N, Minois N, Kroemer G, Madeo F.

Nat Cell Biol. 2009 Nov;11(11):1305-14. doi: 10.1038/ncb1975. Epub 2009 Oct 4.

PMID:
19801973
29.

Nuclear myosin 1 is in complex with mature rRNA transcripts and associates with the nuclear pore basket.

Obrdlik A, Louvet E, Kukalev A, Naschekin D, Kiseleva E, Fahrenkrog B, Percipalle P.

FASEB J. 2010 Jan;24(1):146-57. doi: 10.1096/fj.09-135863. Epub 2009 Sep 3.

PMID:
19729515
30.

Biology and biophysics of the nuclear pore complex and its components.

Lim RY, Ullman KS, Fahrenkrog B.

Int Rev Cell Mol Biol. 2008;267:299-342. doi: 10.1016/S1937-6448(08)00632-1. Review.

31.

Negative regulation of apoptosis in yeast.

Owsianowski E, Walter D, Fahrenkrog B.

Biochim Biophys Acta. 2008 Jul;1783(7):1303-10. doi: 10.1016/j.bbamcr.2008.03.006. Epub 2008 Mar 25. Review.

32.

Towards reconciling structure and function in the nuclear pore complex.

Lim RY, Aebi U, Fahrenkrog B.

Histochem Cell Biol. 2008 Feb;129(2):105-16. doi: 10.1007/s00418-007-0371-x. Epub 2008 Jan 29. Review.

33.

Nanomechanical basis of selective gating by the nuclear pore complex.

Lim RY, Fahrenkrog B, Köser J, Schwarz-Herion K, Deng J, Aebi U.

Science. 2007 Oct 26;318(5850):640-3. Epub 2007 Oct 4.

34.

Domain topology of the p62 complex within the 3-D architecture of the nuclear pore complex.

Schwarz-Herion K, Maco B, Sauder U, Fahrenkrog B.

J Mol Biol. 2007 Jul 20;370(4):796-806. Epub 2007 May 18.

PMID:
17544442
35.

Changes in nucleoporin domain topology in response to chemical effectors.

Paulillo SM, Powers MA, Ullman KS, Fahrenkrog B.

J Mol Biol. 2006 Oct 13;363(1):39-50. Epub 2006 Aug 12.

PMID:
16962132
36.

Getting across the nuclear pore complex: new insights into nucleocytoplasmic transport.

Stoffler D, Schwarz-Herion K, Aebi U, Fahrenkrog B.

Can J Physiol Pharmacol. 2006 Mar-Apr;84(3-4):499-507.

PMID:
16902595
37.

The nuclear pore complex, nuclear transport, and apoptosis.

Fahrenkrog B.

Can J Physiol Pharmacol. 2006 Mar-Apr;84(3-4):279-86. Review.

PMID:
16902575
38.

Single hepatitis-B virus core capsid binding to individual nuclear pore complexes in Hela cells.

Lill Y, Lill MA, Fahrenkrog B, Schwarz-Herion K, Paulillo S, Aebi U, Hecht B.

Biophys J. 2006 Oct 15;91(8):3123-30. Epub 2006 Jul 28.

39.

Flexible phenylalanine-glycine nucleoporins as entropic barriers to nucleocytoplasmic transport.

Lim RY, Huang NP, Köser J, Deng J, Lau KH, Schwarz-Herion K, Fahrenkrog B, Aebi U.

Proc Natl Acad Sci U S A. 2006 Jun 20;103(25):9512-7. Epub 2006 Jun 12.

40.

Nuclear pore complex structure and plasticity revealed by electron and atomic force microscopy.

Maco B, Fahrenkrog B, Huang NP, Aebi U.

Methods Mol Biol. 2006;322:273-88. Review.

PMID:
16739730
41.

The nuclear pore complex up close.

Lim RY, Fahrenkrog B.

Curr Opin Cell Biol. 2006 Jun;18(3):342-7. Epub 2006 May 2. Review.

PMID:
16631361
42.

The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in S. cerevisiae and is a substrate for the yeast homologue of Omi/HtrA2.

Walter D, Wissing S, Madeo F, Fahrenkrog B.

J Cell Sci. 2006 May 1;119(Pt 9):1843-51. Epub 2006 Apr 11.

43.

Nucleoporin domain topology is linked to the transport status of the nuclear pore complex.

Paulillo SM, Phillips EM, Köser J, Sauder U, Ullman KS, Powers MA, Fahrenkrog B.

J Mol Biol. 2005 Aug 26;351(4):784-98.

PMID:
16045929
44.

Lamin A/C-dependent localization of Nesprin-2, a giant scaffolder at the nuclear envelope.

Libotte T, Zaim H, Abraham S, Padmakumar VC, Schneider M, Lu W, Munck M, Hutchison C, Wehnert M, Fahrenkrog B, Sauder U, Aebi U, Noegel AA, Karakesisoglou I.

Mol Biol Cell. 2005 Jul;16(7):3411-24. Epub 2005 Apr 20.

45.

The karyopherin Msn5/Kap142 requires Nup82 for nuclear export and performs a function distinct from translocation in RPA protein import.

Belanger KD, Simmons LA, Roth JK, VanderPloeg KA, Lichten LB, Fahrenkrog B.

J Biol Chem. 2004 Oct 15;279(42):43530-9. Epub 2004 Aug 4.

46.

The nuclear pore complex: a jack of all trades?

Fahrenkrog B, Köser J, Aebi U.

Trends Biochem Sci. 2004 Apr;29(4):175-82. Review. No abstract available.

PMID:
15082311
47.
48.

The nuclear pore complex: nucleocytoplasmic transport and beyond.

Fahrenkrog B, Aebi U.

Nat Rev Mol Cell Biol. 2003 Oct;4(10):757-66. Review.

PMID:
14570049
49.

Cryo-electron tomography provides novel insights into nuclear pore architecture: implications for nucleocytoplasmic transport.

Stoffler D, Feja B, Fahrenkrog B, Walz J, Typke D, Aebi U.

J Mol Biol. 2003 Apr 18;328(1):119-30.

PMID:
12684002
50.

Sac3 is an mRNA export factor that localizes to cytoplasmic fibrils of nuclear pore complex.

Lei EP, Stern CA, Fahrenkrog B, Krebber H, Moy TI, Aebi U, Silver PA.

Mol Biol Cell. 2003 Mar;14(3):836-47.

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