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Items: 1 to 50 of 139


Contribution of the Greenland Ice Sheet to sea level over the next millennium.

Aschwanden A, Fahnestock MA, Truffer M, Brinkerhoff DJ, Hock R, Khroulev C, Mottram R, Khan SA.

Sci Adv. 2019 Jun 19;5(6):eaav9396. doi: 10.1126/sciadv.aav9396. eCollection 2019 Jun.


No changes in corticospinal excitability, biochemical markers, and working memory after six weeks of high-intensity interval training in sedentary males.

Nicolini C, Toepp S, Harasym D, Michalski B, Fahnestock M, Gibala MJ, Nelson AJ.

Physiol Rep. 2019 Jun;7(11):e14140. doi: 10.14814/phy2.14140.


Elucidating the ecological networks in stone-dwelling microbiomes.

Louati M, Ennis NJ, Ghodhbane-Gtari F, Hezbri K, Sevigny JL, Fahnestock MF, Cherif-Silini H, Bryce JG, Tisa LS, Gtari M.

Environ Microbiol. 2019 Jun 3. doi: 10.1111/1462-2920.14700. [Epub ahead of print]


The Effects of Biological Sex and Ovarian Hormones on Exercise-Induced Neuroplasticity.

El-Sayes J, Turco CV, Skelly LE, Nicolini C, Fahnestock M, Gibala MJ, Nelson AJ.

Neuroscience. 2019 Jul 1;410:29-40. doi: 10.1016/j.neuroscience.2019.04.054. Epub 2019 May 8.


ProNGF and Neurodegeneration in Alzheimer's Disease.

Fahnestock M, Shekari A.

Front Neurosci. 2019 Feb 22;13:129. doi: 10.3389/fnins.2019.00129. eCollection 2019. Review.


A large impact crater beneath Hiawatha Glacier in northwest Greenland.

Kjær KH, Larsen NK, Binder T, Bjørk AA, Eisen O, Fahnestock MA, Funder S, Garde AA, Haack H, Helm V, Houmark-Nielsen M, Kjeldsen KK, Khan SA, Machguth H, McDonald I, Morlighem M, Mouginot J, Paden JD, Waight TE, Weikusat C, Willerslev E, MacGregor JA.

Sci Adv. 2018 Nov 14;4(11):eaar8173. doi: 10.1126/sciadv.aar8173. eCollection 2018 Nov.


Corrigendum to "Effects of aerobic training, resistance training, or both on brain-derived neurotrophic factor in adolescents with obesity: The hearty randomized controlled trial" Physiology & Behavior, Volume 191, 1 July 2018, Pages 138-145.

Goldfield GS, Kenny GP, Prud'homme D, Holcik M, Alberga AS, Fahnestock M, Cameron JD, Doucette S, Hadjiyannakis S, Tulloch H, Tremblay MS, Walsh J, Guerin E, Gunnell KE, D'Angiulli A, Sigal RJ.

Physiol Behav. 2019 Jan 1;198:161. doi: 10.1016/j.physbeh.2018.06.019. Epub 2018 Jun 30. No abstract available.


Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models.

Brown EA, Lautz JD, Davis TR, Gniffke EP, VanSchoiack AAW, Neier SC, Tashbook N, Nicolini C, Fahnestock M, Schrum AG, Smith SEP.

Mol Autism. 2018 Sep 15;9:48. doi: 10.1186/s13229-018-0229-1. eCollection 2018.


Early Intervention with a Multi-Ingredient Dietary Supplement Improves Mood and Spatial Memory in a Triple Transgenic Mouse Model of Alzheimer's Disease.

Hutton CP, Lemon JA, Sakic B, Rollo CD, Boreham DR, Fahnestock M, Wojtowicz JM, Becker S.

J Alzheimers Dis. 2018;64(3):835-857. doi: 10.3233/JAD-170921.


The Microglial Innate Immune Receptor TREM2 Is Required for Synapse Elimination and Normal Brain Connectivity.

Filipello F, Morini R, Corradini I, Zerbi V, Canzi A, Michalski B, Erreni M, Markicevic M, Starvaggi-Cucuzza C, Otero K, Piccio L, Cignarella F, Perrucci F, Tamborini M, Genua M, Rajendran L, Menna E, Vetrano S, Fahnestock M, Paolicelli RC, Matteoli M.

Immunity. 2018 May 15;48(5):979-991.e8. doi: 10.1016/j.immuni.2018.04.016. Epub 2018 May 8.


Sex-Dependent Differences in Spontaneous Autoimmunity in Adult 3xTg-AD Mice.

Kapadia M, Mian MF, Michalski B, Azam AB, Ma D, Salwierz P, Christopher A, Rosa E, Zovkic IB, Forsythe P, Fahnestock M, Sakic B.

J Alzheimers Dis. 2018;63(3):1191-1205. doi: 10.3233/JAD-170779.


Neuroimmunologic and Neurotrophic Interactions in Autism Spectrum Disorders: Relationship to Neuroinflammation.

Ohja K, Gozal E, Fahnestock M, Cai L, Cai J, Freedman JH, Switala A, El-Baz A, Barnes GN.

Neuromolecular Med. 2018 Jun;20(2):161-173. doi: 10.1007/s12017-018-8488-8. Epub 2018 Apr 24. Review.


Effects of aerobic training, resistance training, or both on brain-derived neurotrophic factor in adolescents with obesity: The hearty randomized controlled trial.

Goldfield GS, Kenny GP, Prud'homme D, Holcik M, Alberga AS, Fahnestock M, Cameron JD, Doucette S, Hadjiyannakis S, Tulloch H, Tremblay MS, Walsh J, Guerin E, Gunnell KE, D'Angiulli A, Sigal RJ.

Physiol Behav. 2018 Jul 1;191:138-145. doi: 10.1016/j.physbeh.2018.04.026. Epub 2018 Apr 19. Erratum in: Physiol Behav. 2019 Jan 1;198:161.


The serine protease inhibitor neuroserpin is required for normal synaptic plasticity and regulates learning and social behavior.

Reumann R, Vierk R, Zhou L, Gries F, Kraus V, Mienert J, Romswinkel E, Morellini F, Ferrer I, Nicolini C, Fahnestock M, Rune G, Glatzel M, Galliciotti G.

Learn Mem. 2017 Nov 15;24(12):650-659. doi: 10.1101/lm.045864.117. Print 2017 Dec.


Differential deregulation of NGF and BDNF neurotrophins in a transgenic rat model of Alzheimer's disease.

Iulita MF, Bistué Millón MB, Pentz R, Aguilar LF, Do Carmo S, Allard S, Michalski B, Wilson EN, Ducatenzeiler A, Bruno MA, Fahnestock M, Cuello AC.

Neurobiol Dis. 2017 Dec;108:307-323. doi: 10.1016/j.nbd.2017.08.019. Epub 2017 Sep 1.


The Effects of Physical Exercise and Cognitive Training on Memory and Neurotrophic Factors.

Heisz JJ, Clark IB, Bonin K, Paolucci EM, Michalski B, Becker S, Fahnestock M.

J Cogn Neurosci. 2017 Nov;29(11):1895-1907. doi: 10.1162/jocn_a_01164. Epub 2017 Jul 12.


The valproic acid-induced rodent model of autism.

Nicolini C, Fahnestock M.

Exp Neurol. 2018 Jan;299(Pt A):217-227. doi: 10.1016/j.expneurol.2017.04.017. Epub 2017 May 2. Review.


ProNGF, but Not NGF, Switches from Neurotrophic to Apoptotic Activity in Response to Reductions in TrkA Receptor Levels.

Ioannou MS, Fahnestock M.

Int J Mol Sci. 2017 Mar 9;18(3). pii: E599. doi: 10.3390/ijms18030599.


A synthesis of the basal thermal state of the Greenland Ice Sheet.

MacGregor JA, Fahnestock MA, Catania GA, Aschwanden A, Clow GD, Colgan WT, Gogineni SP, Morlighem M, Nowicki SM, Paden JD, Price SF, Seroussi H.

J Geophys Res Earth Surf. 2016 Aug 10;121(7):1328-1350. doi: 10.1002/2015JF003803. Epub 2016 Jul 23.


Electrical muscle stimulation elevates intramuscular BDNF and GDNF mRNA following peripheral nerve injury and repair in rats.

Willand MP, Rosa E, Michalski B, Zhang JJ, Gordon T, Fahnestock M, Borschel GH.

Neuroscience. 2016 Oct 15;334:93-104. doi: 10.1016/j.neuroscience.2016.07.040. Epub 2016 Jul 29.


Tau downregulates BDNF expression in animal and cellular models of Alzheimer's disease.

Rosa E, Mahendram S, Ke YD, Ittner LM, Ginsberg SD, Fahnestock M.

Neurobiol Aging. 2016 Dec;48:135-142. doi: 10.1016/j.neurobiolaging.2016.08.020. Epub 2016 Aug 31.


Cholinergic Surveillance over Hippocampal RNA Metabolism and Alzheimer's-Like Pathology.

Kolisnyk B, Al-Onaizi M, Soreq L, Barbash S, Bekenstein U, Haberman N, Hanin G, Kish MT, Souza da Silva J, Fahnestock M, Ule J, Soreq H, Prado VF, Prado MAM.

Cereb Cortex. 2017 Jul 1;27(7):3553-3567. doi: 10.1093/cercor/bhw177.


Holocene deceleration of the Greenland Ice Sheet.

MacGregor JA, Colgan WT, Fahnestock MA, Morlighem M, Catania GA, Paden JD, Gogineni SP.

Science. 2016 Feb 5;351(6273):590-3. doi: 10.1126/science.aab1702. Epub 2016 Feb 4.


Complex Greenland outlet glacier flow captured.

Aschwanden A, Fahnestock MA, Truffer M.

Nat Commun. 2016 Feb 1;7:10524. doi: 10.1038/ncomms10524.


Cerebrospinal Fluid proNGF: A Putative Biomarker for Early Alzheimer's Disease.

Counts SE, He B, Prout JG, Michalski B, Farotti L, Fahnestock M, Mufson EJ.

Curr Alzheimer Res. 2016;13(7):800-8.


Brain-derived neurotrophic factor and TrkB expression in the "oldest-old," the 90+ Study: correlation with cognitive status and levels of soluble amyloid-beta.

Michalski B, Corrada MM, Kawas CH, Fahnestock M.

Neurobiol Aging. 2015 Dec;36(12):3130-3139. doi: 10.1016/j.neurobiolaging.2015.08.022. Epub 2015 Aug 29.


Synergistic effects of diet and exercise on hippocampal function in chronically stressed mice.

Hutton CP, Déry N, Rosa E, Lemon JA, Rollo CD, Boreham DR, Fahnestock M, deCatanzaro D, Wojtowicz JM, Becker S.

Neuroscience. 2015 Nov 12;308:180-93. doi: 10.1016/j.neuroscience.2015.09.005. Epub 2015 Sep 7.


Radiostratigraphy and age structure of the Greenland Ice Sheet.

MacGregor JA, Fahnestock MA, Catania GA, Paden JD, Prasad Gogineni S, Young SK, Rybarski SC, Mabrey AN, Wagman BM, Morlighem M.

J Geophys Res Earth Surf. 2015 Feb;120(2):212-241. Epub 2015 Feb 13.


CREB expression mediates amyloid β-induced basal BDNF downregulation.

Rosa E, Fahnestock M.

Neurobiol Aging. 2015 Aug;36(8):2406-13. doi: 10.1016/j.neurobiolaging.2015.04.014. Epub 2015 Apr 30.


Decreased mTOR signaling pathway in human idiopathic autism and in rats exposed to valproic acid.

Nicolini C, Ahn Y, Michalski B, Rho JM, Fahnestock M.

Acta Neuropathol Commun. 2015 Jan 20;3:3. doi: 10.1186/s40478-015-0184-4.


Calcitonin gene-related peptide regulation of glial cell-line derived neurotrophic factor in differentiated rat myotubes.

Rosa E, Cha J, Bain JR, Fahnestock M.

J Neurosci Res. 2015 Mar;93(3):514-20. doi: 10.1002/jnr.23512. Epub 2014 Nov 18.


Sensory nerve cross-anastomosis and electrical muscle stimulation synergistically enhance functional recovery of chronically denervated muscle.

Willand MP, Holmes M, Bain JR, de Bruin H, Fahnestock M.

Plast Reconstr Surg. 2014 Nov;134(5):736e-745e. doi: 10.1097/PRS.0000000000000599.


Attenuation of mania-like behavior in Na(+),K(+)-ATPase α3 mutant mice by prospective therapies for bipolar disorder: melatonin and exercise.

Kirshenbaum GS, Burgess CR, Déry N, Fahnestock M, Peever JH, Roder JC.

Neuroscience. 2014 Feb 28;260:195-204. doi: 10.1016/j.neuroscience.2013.12.011. Epub 2013 Dec 14.


The prion protein ligand, stress-inducible phosphoprotein 1, regulates amyloid-β oligomer toxicity.

Ostapchenko VG, Beraldo FH, Mohammad AH, Xie YF, Hirata PH, Magalhaes AC, Lamour G, Li H, Maciejewski A, Belrose JC, Teixeira BL, Fahnestock M, Ferreira ST, Cashman NR, Hajj GN, Jackson MF, Choy WY, MacDonald JF, Martins VR, Prado VF, Prado MA.

J Neurosci. 2013 Oct 16;33(42):16552-64. doi: 10.1523/JNEUROSCI.3214-13.2013. Erratum in: J Neurosci. 2015 Jan 28;35(4):1816.


Increased pro-nerve growth factor and decreased brain-derived neurotrophic factor in non-Alzheimer's disease tauopathies.

Belrose JC, Masoudi R, Michalski B, Fahnestock M.

Neurobiol Aging. 2014 Apr;35(4):926-33. doi: 10.1016/j.neurobiolaging.2013.08.029. Epub 2013 Oct 8.


A novel anticonvulsant modulates voltage-gated sodium channel inactivation and prevents kindling-induced seizures.

Ashraf MN, Gavrilovici C, Shah SU, Shaheen F, Choudhary MI, Rahman AU, Fahnestock M, Simjee SU, Poulter MO.

J Neurochem. 2013 Sep;126(5):651-61. doi: 10.1111/jnc.12352. Epub 2013 Jul 22.


Eps8 controls dendritic spine density and synaptic plasticity through its actin-capping activity.

Menna E, Zambetti S, Morini R, Donzelli A, Disanza A, Calvigioni D, Braida D, Nicolini C, Orlando M, Fossati G, Cristina Regondi M, Pattini L, Frassoni C, Francolini M, Scita G, Sala M, Fahnestock M, Matteoli M.

EMBO J. 2013 Jun 12;32(12):1730-44. doi: 10.1038/emboj.2013.107. Epub 2013 May 17.


Electrical muscle stimulation after immediate nerve repair reduces muscle atrophy without affecting reinnervation.

Willand MP, Holmes M, Bain JR, Fahnestock M, De Bruin H.

Muscle Nerve. 2013 Aug;48(2):219-25. doi: 10.1002/mus.23726. Epub 2013 May 2.


Overexpression of nerve growth factor by murine smooth muscle cells: role of the p75 neurotrophin receptor on sympathetic and sensory sprouting.

Petrie CN, Smithson LJ, Crotty AM, Michalski B, Fahnestock M, Kawaja MD.

J Comp Neurol. 2013 Aug 1;521(11):2621-43. doi: 10.1002/cne.23302.


Cerebrolysin modulates pronerve growth factor/nerve growth factor ratio and ameliorates the cholinergic deficit in a transgenic model of Alzheimer's disease.

Ubhi K, Rockenstein E, Vazquez-Roque R, Mante M, Inglis C, Patrick C, Adame A, Fahnestock M, Doppler E, Novak P, Moessler H, Masliah E.

J Neurosci Res. 2013 Feb;91(2):167-77. doi: 10.1002/jnr.23142. Epub 2012 Nov 14.


Reduced tissue levels of noradrenaline are associated with behavioral phenotypes of the TgCRND8 mouse model of Alzheimer's disease.

Francis BM, Yang J, Hajderi E, Brown ME, Michalski B, McLaurin J, Fahnestock M, Mount HT.

Neuropsychopharmacology. 2012 Jul;37(8):1934-44. doi: 10.1038/npp.2012.40. Epub 2012 Apr 11.


Altered balance of proteolytic isoforms of pro-brain-derived neurotrophic factor in autism.

Garcia KL, Yu G, Nicolini C, Michalski B, Garzon DJ, Chiu VS, Tongiorgi E, Szatmari P, Fahnestock M.

J Neuropathol Exp Neurol. 2012 Apr;71(4):289-97. doi: 10.1097/NEN.0b013e31824b27e4.


Determining the effects of electrical stimulation on functional recovery of denervated rat gastrocnemius muscle using motor unit number estimation.

Willand MP, Holmes M, Bain JR, Fahnestock M, de Bruin H.

Conf Proc IEEE Eng Med Biol Soc. 2011;2011:1977-80. doi: 10.1109/IEMBS.2011.6090557.


The anxiolytic effect of Bifidobacterium longum NCC3001 involves vagal pathways for gut-brain communication.

Bercik P, Park AJ, Sinclair D, Khoshdel A, Lu J, Huang X, Deng Y, Blennerhassett PA, Fahnestock M, Moine D, Berger B, Huizinga JD, Kunze W, McLean PG, Bergonzelli GE, Collins SM, Verdu EF.

Neurogastroenterol Motil. 2011 Dec;23(12):1132-9. doi: 10.1111/j.1365-2982.2011.01796.x. Epub 2011 Oct 11.


Nerve growth factor promoter activity revealed in mice expressing enhanced green fluorescent protein.

Kawaja MD, Smithson LJ, Elliott J, Trinh G, Crotty AM, Michalski B, Fahnestock M.

J Comp Neurol. 2011 Sep 1;519(13):2522-45. doi: 10.1002/cne.22629.


A New System and Paradigm for Chronic Stimulation of Denervated Rat Muscle.

Willand MP, Lopez JP, de Bruin H, Fahnestock M, Holmes M, Bain JR.

J Med Biol Eng. 2011;31(2):87-92.


Cholinotrophic basal forebrain system alterations in 3xTg-AD transgenic mice.

Perez SE, He B, Muhammad N, Oh KJ, Fahnestock M, Ikonomovic MD, Mufson EJ.

Neurobiol Dis. 2011 Feb;41(2):338-52. doi: 10.1016/j.nbd.2010.10.002. Epub 2010 Oct 16.


BDNF increases with behavioral enrichment and an antioxidant diet in the aged dog.

Fahnestock M, Marchese M, Head E, Pop V, Michalski B, Milgram WN, Cotman CW.

Neurobiol Aging. 2012 Mar;33(3):546-54. doi: 10.1016/j.neurobiolaging.2010.03.019. Epub 2010 May 5.


Object recognition memory and BDNF expression are reduced in young TgCRND8 mice.

Francis BM, Kim J, Barakat ME, Fraenkl S, Yücel YH, Peng S, Michalski B, Fahnestock M, McLaurin J, Mount HT.

Neurobiol Aging. 2012 Mar;33(3):555-63. doi: 10.1016/j.neurobiolaging.2010.04.003. Epub 2010 May 5.


Sensory protection of rat muscle spindles following peripheral nerve injury and reinnervation.

Elsohemy A, Butler R, Bain JR, Fahnestock M.

Plast Reconstr Surg. 2009 Dec;124(6):1860-8. doi: 10.1097/PRS.0b013e3181bcee47.

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