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Items: 1 to 50 of 52

1.

Cyclin-dependent kinase 8/19 inhibition suppresses osteoclastogenesis by downregulating RANK and promotes osteoblast mineralization and cancellous bone healing.

Amirhosseini M, Bernhardsson M, Lång P, Andersson G, Flygare J, Fahlgren A.

J Cell Physiol. 2019 Feb 21. doi: 10.1002/jcp.28321. [Epub ahead of print]

PMID:
30793301
2.

Accumulation of virulence-associated proteins in Campylobacter jejuni Outer Membrane Vesicles at human body temperature.

Taheri N, Fällman M, Wai SN, Fahlgren A.

J Proteomics. 2019 Mar 20;195:33-40. doi: 10.1016/j.jprot.2019.01.005. Epub 2019 Jan 11.

PMID:
30641234
3.

Mechanical loading releases osteoclastogenesis-modulating factors through stimulation of the P2X7 receptor in hematopoietic progenitor cells.

Bratengeier C, Bakker AD, Fahlgren A.

J Cell Physiol. 2019 Aug;234(8):13057-13067. doi: 10.1002/jcp.27976. Epub 2018 Dec 7.

PMID:
30536959
4.

Campylobacter jejuni bile exposure influences outer membrane vesicles protein content and bacterial interaction with epithelial cells.

Taheri N, Mahmud AKMF, Sandblad L, Fällman M, Wai SN, Fahlgren A.

Sci Rep. 2018 Nov 19;8(1):16996. doi: 10.1038/s41598-018-35409-0.

5.

Supraphysiological loading induces osteocyte-mediated osteoclastogenesis in a novel in vitro model for bone implant loosening.

Fahlgren A, Bratengeier C, Semeins CM, Klein-Nulend J, Bakker AD.

J Orthop Res. 2018 May;36(5):1425-1434. doi: 10.1002/jor.23780. Epub 2017 Nov 22.

6.

Mechanical instability and titanium particles induce similar transcriptomic changes in a rat model for periprosthetic osteolysis and aseptic loosening.

Amirhosseini M, Andersson G, Aspenberg P, Fahlgren A.

Bone Rep. 2017 Jul 29;7:17-25. doi: 10.1016/j.bonr.2017.07.003. eCollection 2017 Dec.

7.

GSK-3β inhibition suppresses instability-induced osteolysis by a dual action on osteoblast and osteoclast differentiation.

Amirhosseini M, Madsen RV, Escott KJ, Bostrom MP, Ross FP, Fahlgren A.

J Cell Physiol. 2018 Mar;233(3):2398-2408. doi: 10.1002/jcp.26111. Epub 2017 Sep 28.

8.

The Tat Substrate SufI Is Critical for the Ability of Yersinia pseudotuberculosis To Cause Systemic Infection.

Avican U, Doruk T, Östberg Y, Fahlgren A, Forsberg Å.

Infect Immun. 2017 Mar 23;85(4). pii: e00867-16. doi: 10.1128/IAI.00867-16. Print 2017 Apr.

9.

Yersinia pseudotuberculosis Blocks Neutrophil Degranulation.

Taheri N, Fahlgren A, Fällman M.

Infect Immun. 2016 Nov 18;84(12):3369-3378. Print 2016 Dec.

10.

Increased plasmid copy number is essential for Yersinia T3SS function and virulence.

Wang H, Avican K, Fahlgren A, Erttmann SF, Nuss AM, Dersch P, Fallman M, Edgren T, Wolf-Watz H.

Science. 2016 Jul 29;353(6298):492-5. doi: 10.1126/science.aaf7501. Epub 2016 Jun 30.

11.

Biocompatibility of Polypyrrole with Human Primary Osteoblasts and the Effect of Dopants.

Fahlgren A, Bratengeier C, Gelmi A, Semeins CM, Klein-Nulend J, Jager EW, Bakker AD.

PLoS One. 2015 Jul 30;10(7):e0134023. doi: 10.1371/journal.pone.0134023. eCollection 2015.

12.

Reprogramming of Yersinia from virulent to persistent mode revealed by complex in vivo RNA-seq analysis.

Avican K, Fahlgren A, Huss M, Heroven AK, Beckstette M, Dersch P, Fällman M.

PLoS Pathog. 2015 Jan 15;11(1):e1004600. doi: 10.1371/journal.ppat.1004600. eCollection 2015 Jan. Erratum in: PLoS Pathog. 2015 Mar;11(3):e1004769.

13.

Intermittent PTH administration and mechanical loading are anabolic for periprosthetic cancellous bone.

Grosso MJ, Courtland HW, Yang X, Sutherland JP, Stoner K, Nguyen J, Fahlgren A, Ross FP, van der Meulen MC, Bostrom MP.

J Orthop Res. 2015 Feb;33(2):163-73. doi: 10.1002/jor.22748. Epub 2014 Nov 18.

14.

Maladjusted host immune responses induce experimental cerebral malaria-like pathology in a murine Borrelia and Plasmodium co-infection model.

Normark J, Nelson M, Engström P, Andersson M, Björk R, Moritz T, Fahlgren A, Bergström S.

PLoS One. 2014 Jul 30;9(7):e103295. doi: 10.1371/journal.pone.0103295. eCollection 2014.

15.

Colonization of cecum is important for development of persistent infection by Yersinia pseudotuberculosis.

Fahlgren A, Avican K, Westermark L, Nordfelth R, Fällman M.

Infect Immun. 2014 Aug;82(8):3471-82. doi: 10.1128/IAI.01793-14. Epub 2014 Jun 2.

16.

Yersinia pseudotuberculosis efficiently escapes polymorphonuclear neutrophils during early infection.

Westermark L, Fahlgren A, Fällman M.

Infect Immun. 2014 Mar;82(3):1181-91. doi: 10.1128/IAI.01634-13. Epub 2013 Dec 30.

17.

Emerging ideas: Instability-induced periprosthetic osteolysis is not dependent on the fibrous tissue interface.

Nam D, Bostrom MP, Fahlgren A.

Clin Orthop Relat Res. 2013 Jun;471(6):1758-62. doi: 10.1007/s11999-013-2896-8. Epub 2013 Mar 6.

18.

Metabolic profiling for detection of Staphylococcus aureus infection and antibiotic resistance.

Antti H, Fahlgren A, Näsström E, Kouremenos K, Sundén-Cullberg J, Guo Y, Moritz T, Wolf-Watz H, Johansson A, Fallman M.

PLoS One. 2013;8(2):e56971. doi: 10.1371/journal.pone.0056971. Epub 2013 Feb 25.

19.

Type III secretion translocon assemblies that attenuate Yersinia virulence.

Costa TR, Amer AA, Farag SI, Wolf-Watz H, Fällman M, Fahlgren A, Edgren T, Francis MS.

Cell Microbiol. 2013 Jul;15(7):1088-110. doi: 10.1111/cmi.12100. Epub 2013 Jan 21.

PMID:
23279117
20.

Role of YopK in Yersinia pseudotuberculosis resistance against polymorphonuclear leukocyte defense.

Thorslund SE, Ermert D, Fahlgren A, Erttmann SF, Nilsson K, Hosseinzadeh A, Urban CF, Fällman M.

Infect Immun. 2013 Jan;81(1):11-22. doi: 10.1128/IAI.00650-12. Epub 2012 Oct 22.

21.

Coiled-coils in the YopD translocator family: a predicted structure unique to the YopD N-terminus contributes to full virulence of Yersinia pseudotuberculosis.

Costa TR, Amer AA, Fällman M, Fahlgren A, Francis MS.

Infect Genet Evol. 2012 Dec;12(8):1729-42. doi: 10.1016/j.meegid.2012.07.016. Epub 2012 Aug 11.

PMID:
22910185
22.

Direct ex vivo measurement of the fluid permeability of loose scar tissue.

Fahlgren A, Johansson L, Edlund U, Aspenberg P.

Acta Bioeng Biomech. 2012;14(2):47-51.

PMID:
22793501
23.

Immune response to diphtheria toxin-mediated depletion complicates the use of the CD11c-DTR(tg) model for studies of bacterial gastrointestinal infections.

Westermark L, Fahlgren A, Fällman M.

Microb Pathog. 2012 Sep;53(3-4):154-61. doi: 10.1016/j.micpath.2012.06.004. Epub 2012 Jul 6.

PMID:
22771374
24.

Lipopolysaccharide O-antigen prevents phagocytosis of Vibrio anguillarum by rainbow trout (Oncorhynchus mykiss) skin epithelial cells.

Lindell K, Fahlgren A, Hjerde E, Willassen NP, Fällman M, Milton DL.

PLoS One. 2012;7(5):e37678. doi: 10.1371/journal.pone.0037678. Epub 2012 May 25.

25.

The effects of PTH, loading and surgical insult on cancellous bone at the bone-implant interface in the rabbit.

Fahlgren A, Yang X, Ciani C, Ryan JA, Kelly N, Ko FC, van der Meulen MC, Bostrom MP.

Bone. 2013 Feb;52(2):718-24. doi: 10.1016/j.bone.2012.05.005. Epub 2012 May 18.

26.

Fluid pressure induces osteoclast differentiation comparably to titanium particles but through a molecular pathway only partly involving TNFα.

Nilsson A, Norgård M, Andersson G, Fahlgren A.

J Cell Biochem. 2012 Apr;113(4):1224-34. doi: 10.1002/jcb.23456.

PMID:
22095724
27.

Fluid-induced osteolysis: modelling and experiments.

Johansson L, Edlund U, Fahlgren A, Aspenberg P.

Comput Methods Biomech Biomed Engin. 2011 Apr;14(4):305-18. doi: 10.1080/10255842.2010.484808.

PMID:
21390935
28.

Translocation of surface-localized effectors in type III secretion.

Akopyan K, Edgren T, Wang-Edgren H, Rosqvist R, Fahlgren A, Wolf-Watz H, Fallman M.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1639-44. doi: 10.1073/pnas.1013888108. Epub 2011 Jan 10.

29.

Chronic colitis induces expression of β-defensins in murine intestinal epithelial cells.

Rahman A, Fahlgren A, Sundstedt C, Hammarström S, Danielsson A, Hammarström ML.

Clin Exp Immunol. 2011 Jan;163(1):123-30. doi: 10.1111/j.1365-2249.2010.04282.x. Epub 2010 Oct 29.

30.

Targeting RANKL for reduction of bone loss around unstable implants: OPG-Fc compared to alendronate in a model for mechanically induced loosening.

Aspenberg P, Agholme F, Magnusson P, Fahlgren A.

Bone. 2011 Feb;48(2):225-30. doi: 10.1016/j.bone.2010.09.024. Epub 2010 Sep 19.

PMID:
20858557
31.

Fluid pressure and flow as a cause of bone resorption.

Fahlgren A, Bostrom MP, Yang X, Johansson L, Edlund U, Agholme F, Aspenberg P.

Acta Orthop. 2010 Aug;81(4):508-16. doi: 10.3109/17453674.2010.504610.

32.

Histology of an undisplaced femoral fatigue fracture in association with bisphosphonate treatment. Frozen bone with remodelling at the crack.

Aspenberg P, Schilcher J, Fahlgren A.

Acta Orthop. 2010 Aug;81(4):460-2. doi: 10.3109/17453674.2010.492766. No abstract available.

33.

Compression therapy promotes proliferative repair during rat Achilles tendon immobilization.

Schizas N, Li J, Andersson T, Fahlgren A, Aspenberg P, Ahmed M, Ackermann PW.

J Orthop Res. 2010 Jul;28(7):852-8. doi: 10.1002/jor.21066.

34.

Bone resorption induced by fluid flow.

Johansson L, Edlund U, Fahlgren A, Aspenberg P.

J Biomech Eng. 2009 Sep;131(9):094505. doi: 10.1115/1.3194756.

PMID:
19725702
35.

The membrane localization domain is required for intracellular localization and autoregulation of YopE in Yersinia pseudotuberculosis.

Isaksson EL, Aili M, Fahlgren A, Carlsson SE, Rosqvist R, Wolf-Watz H.

Infect Immun. 2009 Nov;77(11):4740-9. doi: 10.1128/IAI.00333-09. Epub 2009 Aug 17.

36.

Cell type-specific effects of Yersinia pseudotuberculosis virulence effectors.

Fahlgren A, Westermark L, Akopyan K, Fällman M.

Cell Microbiol. 2009 Dec;11(12):1750-67. doi: 10.1111/j.1462-5822.2009.01365.x. Epub 2009 Aug 4.

PMID:
19681909
37.

Early Achilles tendon healing in sheep.

Virchenko O, Fahlgren A, Rundgren M, Aspenberg P.

Arch Orthop Trauma Surg. 2008 Sep;128(9):1001-6. doi: 10.1007/s00402-008-0691-x. Epub 2008 Jul 4.

PMID:
18600332
38.

Mechanical load and BMP signaling during tendon repair: a role for follistatin?

Eliasson P, Fahlgren A, Aspenberg P.

Clin Orthop Relat Res. 2008 Jul;466(7):1592-7. doi: 10.1007/s11999-008-0253-0. Epub 2008 Apr 18.

39.

Additive effects of PTH and bisphosphonates on the bone healing response to metaphyseal implants in rats.

Aspenberg P, Wermelin K, Tengwall P, Fahlgren A.

Acta Orthop. 2008 Feb;79(1):111-5. doi: 10.1080/17453670710014851.

PMID:
18283582
40.

Unloaded rat Achilles tendons continue to grow, but lose viscoelasticity.

Eliasson P, Fahlgren A, Pasternak B, Aspenberg P.

J Appl Physiol (1985). 2007 Aug;103(2):459-63. Epub 2007 Apr 5.

41.

Beta-defensin production by human colonic plasma cells: a new look at plasma cells in ulcerative colitis.

Rahman A, Fahlgren A, Sitohy B, Baranov V, Zirakzadeh A, Hammarström S, Danielsson A, Hammarström ML.

Inflamm Bowel Dis. 2007 Jul;13(7):847-55.

PMID:
17387677
42.

Improved healing of ligament to bone with point fixation in rabbits.

Khoschnau S, Fahlgren A, Aspenberg P, Rahme H.

Acta Orthop. 2006 Dec;77(6):967-72.

PMID:
17260209
43.

A capsular incision leads to a fast osteoarthritic response, but also elevated levels of activated osteogenic protein-1 in rabbit knee joint cartilage.

Fahlgren A, Chubinskaya S, Messner K, Aspenberg P.

Scand J Med Sci Sports. 2006 Dec;16(6):456-62.

PMID:
17121649
44.

CDMP-2 injection improves early tendon healing in a rabbit model for surgical repair.

Virchenko O, Fahlgren A, Skoglund B, Aspenberg P.

Scand J Med Sci Sports. 2005 Aug;15(4):260-4.

PMID:
15998343
45.

beta-Defensin-3 and -4 in intestinal epithelial cells display increased mRNA expression in ulcerative colitis.

Fahlgren A, Hammarstrom S, Danielsson A, Hammarstrom ML.

Clin Exp Immunol. 2004 Aug;137(2):379-85.

46.

Presence of bacteria and innate immunity of intestinal epithelium in childhood celiac disease.

Forsberg G, Fahlgren A, Hörstedt P, Hammarström S, Hernell O, Hammarström ML.

Am J Gastroenterol. 2004 May;99(5):894-904. Erratum in: Am J Gastroenterol. 2004 Jul;99(7):following 1406.

PMID:
15128357
47.

Interferon-gamma tempers the expression of carcinoembryonic antigen family molecules in human colon cells: a possible role in innate mucosal defence.

Fahlgren A, Baranov V, Frängsmyr L, Zoubir F, Hammarström ML, Hammarström S.

Scand J Immunol. 2003 Dec;58(6):628-41.

48.

Meniscectomy leads to an early increase in subchondral bone plate thickness in the rabbit knee.

Fahlgren A, Messner K, Aspenberg P.

Acta Orthop Scand. 2003 Aug;74(4):437-41.

PMID:
14521295
49.

Increased expression of antimicrobial peptides and lysozyme in colonic epithelial cells of patients with ulcerative colitis.

Fahlgren A, Hammarström S, Danielsson A, Hammarström ML.

Clin Exp Immunol. 2003 Jan;131(1):90-101.

50.

TGF-beta1 as a prognostic factor in the process of early osteoarthrosis in the rabbit knee.

Fahlgren A, Andersson B, Messner K.

Osteoarthritis Cartilage. 2001 Apr;9(3):195-202.

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