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In Vivo Assessment of VCAM-1 Expression by SPECT/CT Imaging in Mice Models of Human Triple Negative Breast Cancer.

Montemagno C, Dumas L, Cavaillès P, Ahmadi M, Bacot S, Debiossat M, Soubies A, Djaïleb L, Leenhardt J, Leiris N, Dufies M, Pagès G, Hernot S, Devoogdt N, Perret P, Riou L, Fagret D, Ghezzi C, Broisat A.

Cancers (Basel). 2019 Jul 23;11(7). pii: E1039. doi: 10.3390/cancers11071039.


Prospective diagnostic performance of semiconductor SPECT myocardial perfusion imaging: wall thickening analysis reduces the need for an additional prone acquisition.

Djaileb L, Dubois B, de Leiris N, Leenhardt J, Canu M, Sy OP, Carabelli A, Boussat B, Dumas L, Broisat A, Vanzetto G, Fagret D, Ghezzi C, Barone-Rochette G, Riou LM.

Eur J Nucl Med Mol Imaging. 2019 Sep;46(10):2042-2050. doi: 10.1007/s00259-019-04415-3. Epub 2019 Jul 18.


Safety, Biodistribution, and Dosimetry of 123I-6-Deoxy-6-Iodo-D-Glucose, a Tracer of Glucose Transport, in Healthy and Diabetic Volunteers.

Calizzano A, Perret P, Desruet MD, Ahmadi M, Reboulet G, Djaileb L, Vanzetto G, Fagret D, Barone-Rochette G, Ghezzi C.

Clin Nucl Med. 2019 May;44(5):386-393. doi: 10.1097/RLU.0000000000002510.


Semi-automatic detection of myocardial trabeculation using cardiovascular magnetic resonance: correlation with histology and reproducibility in a mouse model of non-compaction.

Frandon J, Bricq S, Bentatou Z, Marcadet L, Barral PA, Finas M, Fagret D, Kober F, Habib G, Bernard M, Lalande A, Miquerol L, Jacquier A.

J Cardiovasc Magn Reson. 2018 Oct 25;20(1):70. doi: 10.1186/s12968-018-0489-0.


Mapping of brain tissue hematocrit in glioma and acute stroke using a dual autoradiography approach.

Broisat A, Lemasson B, Ahmadi M, Collomb N, Bacot S, Soubies A, Fagret D, Rémy C, Ghezzi C, Barbier EL.

Sci Rep. 2018 Jun 29;8(1):9878. doi: 10.1038/s41598-018-28082-w.


Suboptimal performance of cardiovascular magnetic resonance imaging for the assessment of myocardial viability at the early phase of an acute coronary syndrome: Usefulness of SPECT myocardial perfusion imaging.

Djaileb L, Jankowski A, Canu M, Calizzano A, Riou L, Broisat A, Fagret D, Ghezzi C, Vanzetto G, Barone-Rochette G.

J Nucl Cardiol. 2019 Aug;26(4):1365-1367. doi: 10.1007/s12350-018-1352-2. Epub 2018 Jun 26. No abstract available.


Preclinical Evaluation of Mesothelin-Specific Ligands for SPECT Imaging of Triple-Negative Breast Cancer.

Montemagno C, Bacot S, Ahmadi M, Kerfelec B, Baty D, Debiossat M, Soubies A, Perret P, Riou L, Fagret D, Broisat A, Ghezzi C.

J Nucl Med. 2018 Jul;59(7):1056-1062. doi: 10.2967/jnumed.117.203489. Epub 2018 Mar 23.


Diagnostic value of stress thallium-201/rest technetium-99m-sestamibi sequential dual isotope high-speed myocardial perfusion imaging for the detection of haemodynamically relevant coronary artery stenosis.

Barone-Rochette G, Zoreka F, Djaileb L, Piliero N, Calizzano A, Quesada JL, Broisat A, Riou L, Machecourt J, Fagret D, Vanzetto G, Ghezzi C.

J Nucl Cardiol. 2019 Aug;26(4):1269-1279. doi: 10.1007/s12350-018-1189-8. Epub 2018 Jan 29.


SPECT myocardial ischemia in the absence of obstructive CAD: Contribution of the invasive assessment of microvascular dysfunction.

Djaïleb L, Riou L, Piliero N, Carabelli A, Vautrin E, Broisat A, Leenhardt J, Machecourt J, Fagret D, Vanzetto G, Barone-Rochette G, Ghezzi C.

J Nucl Cardiol. 2018 Jun;25(3):1017-1022. doi: 10.1007/s12350-017-1135-1. Epub 2017 Dec 5.


Evaluation of Imaging Strategy to Optimize and Improve Outcome of Transcatheter Aortic Valvular Implantation.

Casset C, Jankowski A, Bertrand B, Saunier C, Piliero N, Rodiere M, Ferretti G, Quesada JL, Broisat A, Riou L, Fagret D, Ghezzi C, Vanzetto G, Barone-Rochette G.

Am J Cardiol. 2017 Nov 1;120(9):1633-1638. doi: 10.1016/j.amjcard.2017.07.062. Epub 2017 Jul 31.


Evaluation of Antiatherogenic Properties of Ezetimibe Using 3H-Labeled Low-Density-Lipoprotein Cholesterol and 99mTc-cAbVCAM1-5 SPECT in ApoE-/- Mice Fed the Paigen Diet.

Dumas LS, Briand F, Clerc R, Brousseau E, Montemagno C, Ahmadi M, Bacot S, Soubies A, Perret P, Riou LM, Devoogdt N, Lahoutte T, Barone-Rochette G, Fagret D, Ghezzi C, Sulpice T, Broisat A.

J Nucl Med. 2017 Jul;58(7):1088-1093. doi: 10.2967/jnumed.116.177279. Epub 2017 Mar 9.


Evaluation of a human anti-mouse antibody rapid test for patients requiring radio-immunodiagnostic.

Lamesa C, Gauchez AS, Mazet R, Foroni L, Fagret D, Desruet MD.

Clin Chem Lab Med. 2017 Oct 26;55(11):e259-e261. doi: 10.1515/cclm-2016-0866. No abstract available.


New diketopiperazines as vectors for peptide protection and brain delivery: Synthesis and biological evaluation.

Virgone-Carlotta A, Dufour E, Bacot S, Ahmadi M, Cornou M, Moni L, Garcia J, Chierici S, Garin D, Marti-Batlle D, Perret P, Ghersi-Egea JF, Moulin Sallanon M, Fagret D, Ghezzi C.

J Labelled Comp Radiopharm. 2016 Oct;59(12):517-530. doi: 10.1002/jlcr.3442. Epub 2016 Sep 9.


Sympathetic cardiac function in early sepsis: Noninvasive evaluation with [123I]-meta-iodobenzylguanidine (123I-MIBG) in vivo SPECT imaging.

Clerc R, Doll S, Riou LM, Perret P, Broisat A, Soubies A, Desruet MD, Fagret D, Schwebel C, Ghezzi C.

J Nucl Cardiol. 2018 Apr;25(2):483-491. doi: 10.1007/s12350-016-0619-8. Epub 2016 Aug 29.


Targeting of vascular cell adhesion molecule-1 by 18F-labelled nanobodies for PET/CT imaging of inflamed atherosclerotic plaques.

Bala G, Blykers A, Xavier C, Descamps B, Broisat A, Ghezzi C, Fagret D, Van Camp G, Caveliers V, Vanhove C, Lahoutte T, Droogmans S, Cosyns B, Devoogdt N, Hernot S.

Eur Heart J Cardiovasc Imaging. 2016 Sep;17(9):1001-8. doi: 10.1093/ehjci/jev346. Epub 2016 Jan 22.


Know the strengths and weaknesses of ischemia tests to guide the therapeutic strategy of a patient with multi-vessel disease.

Fluttaz A, Rodière M, Bourre JC, Jankowski A, Descotes-Genon V, Riou L, Broisat A, Ghezzi C, Djaileb L, Calizzano A, Machecourt J, Vanzetto G, Fagret D, Barone-Rochette G.

Int J Cardiol. 2016 Mar 1;206:64-7. doi: 10.1016/j.ijcard.2016.01.002. Epub 2016 Jan 15. No abstract available.


Semiautomatic detection of myocardial contours in order to investigate normal values of the left ventricular trabeculated mass using MRI.

Bricq S, Frandon J, Bernard M, Guye M, Finas M, Marcadet L, Miquerol L, Kober F, Habib G, Fagret D, Jacquier A, Lalande A.

J Magn Reson Imaging. 2016 Jun;43(6):1398-406. doi: 10.1002/jmri.25113. Epub 2015 Dec 9.


In vivo siRNA distribution and pharmacokinetics assessed by nuclear imaging are modulated according to radiolabelling site.

Garin D, Ahmadi M, Gauchez AS, Bohic S, Boccard S, Cloetens P, Fagret D, Berger F, Briat A, Ghezzi C, Pelletier L.

Nucl Med Biol. 2015 Dec;42(12):958-66. doi: 10.1016/j.nucmedbio.2015.04.007. Epub 2015 Apr 24.


Stress thallium-201/rest technetium-99m sequential dual-isotope high-speed myocardial perfusion imaging validation versus invasive coronary angiography.

Barone-Rochette G, Leclere M, Calizzano A, Vautrin E, Céline GC, Broisat A, Ghezzi C, Baguet JP, Machecourt J, Vanzetto G, Fagret D.

J Nucl Cardiol. 2015 Jun;22(3):513-22. doi: 10.1007/s12350-014-0016-0. Epub 2014 Nov 8.


Equivocal usefulness of FDG for the noninvasive imaging of abdominal aortic aneurysms.

Riou LM, Vanzetto G, Broisat A, Fagret D, Ghezzi C.

Eur J Nucl Med Mol Imaging. 2014 Dec;41(12):2307-9. doi: 10.1007/s00259-014-2917-1. No abstract available.


Targeted radionuclide therapy with RAFT-RGD radiolabelled with (90)Y or (177)Lu in a mouse model of αvβ3-expressing tumours.

Bozon-Petitprin A, Bacot S, Gauchez AS, Ahmadi M, Bourre JC, Marti-Batlle D, Perret P, Broisat A, Riou LM, Claron M, Boturyn D, Fagret D, Ghezzi C, Vuillez JP.

Eur J Nucl Med Mol Imaging. 2015 Feb;42(2):252-63. doi: 10.1007/s00259-014-2891-7. Epub 2014 Aug 28.


99mTc-cAbVCAM1-5 imaging is a sensitive and reproducible tool for the detection of inflamed atherosclerotic lesions in mice.

Broisat A, Toczek J, Dumas LS, Ahmadi M, Bacot S, Perret P, Slimani L, Barone-Rochette G, Soubies A, Devoogdt N, Lahoutte T, Fagret D, Riou LM, Ghezzi C.

J Nucl Med. 2014 Oct;55(10):1678-84. doi: 10.2967/jnumed.114.143792. Epub 2014 Aug 25.


Radioiodine therapy in benign thyroid disorders. Evaluation of French nuclear medicine practices.

Bernard D, Desruet MD, Wolf M, Roux J, Boin C, Mazet R, Gallazzini C, Calizzano A, Vuillez JP, Allenet B, Fagret D.

Ann Endocrinol (Paris). 2014 Sep;75(4):241-6. doi: 10.1016/j.ando.2014.07.863. Epub 2014 Aug 22.


Periaortic brown adipose tissue as a major determinant of [¹⁸F]-fluorodeoxyglucose vascular uptake in atherosclerosis-prone, apoE-/- mice.

Toczek J, Broisat A, Perret P, Desruet MD, Fagret D, Riou LM, Ghezzi C.

PLoS One. 2014 Jul 23;9(7):e99441. doi: 10.1371/journal.pone.0099441. eCollection 2014.


Study of inter- and intra-observer reproducibility in the interpretation of [(18)F]choline PET/CT examinations in patients suffering from biochemically recurrent prostate cancer following curative treatment.

Pegard C, Gallazzini-Crépin C, Giai J, Dubreuil J, Caoduro C, Desruet MD, Roux J, Calizzano A, Fagret D, Lamesa C, Boulahdour H, Vuillez JP.

EJNMMI Res. 2014 May 30;4:25. doi: 10.1186/s13550-014-0025-7. eCollection 2014.


Preclinical characterization of a novel radiolabeled analog of practolol for the molecular imaging of myocardial β-adrenoceptor density.

Carbonnelle E, Josserand V, Riou LM, Ormezzano O, Broisat A, Perret P, Barone-Rochette G, Fagret D, Ghezzi C.

J Nucl Cardiol. 2014 Oct;21(5):984-92. doi: 10.1007/s12350-014-9913-5. Epub 2014 May 30.


Quantitative evaluation of the cell penetrating properties of an iodinated Tyr-L-maurocalcine analog.

Tisseyre C, Ahmadi M, Bacot S, Dardevet L, Perret P, Ronjat M, Fagret D, Usson Y, Ghezzi C, De Waard M.

Biochim Biophys Acta. 2014 Oct;1843(10):2356-64. doi: 10.1016/j.bbamcr.2014.03.017. Epub 2014 Mar 22.


Potentially simple score of late gadolinium enhancement cardiac MR in acute myocarditis outcome.

Barone-Rochette G, Augier C, Rodière M, Quesada JL, Foote A, Bouvaist H, Marlière S, Fagret D, Baguet JP, Vanzetto G.

J Magn Reson Imaging. 2014 Dec;40(6):1347-54. doi: 10.1002/jmri.24504. Epub 2013 Dec 1.


In vivo molecular imaging of atherosclerotic lesions in ApoE-/- mice using VCAM-1-specific, 99mTc-labeled peptidic sequences.

Dimastromatteo J, Broisat A, Perret P, Ahmadi M, Boturyn D, Dumy P, Fagret D, Riou LM, Ghezzi C.

J Nucl Med. 2013 Aug;54(8):1442-9. doi: 10.2967/jnumed.112.115675. Epub 2013 May 29.


Diagnosis of cardiac tumors: contribution of non-invasive cardiac imaging in routine practice.

Barone-Rochette G, Augier C, Rodière M, Jankowski A, Thony F, Ferretti G, Saunier C, Lantuejoul S, Chavanon O, Fagret D, Vanzetto G, Baguet JP.

Int J Cardiol. 2012 May 31;157(2):298-300. doi: 10.1016/j.ijcard.2012.03.114. Epub 2012 Apr 6. No abstract available.


Nanobodies targeting mouse/human VCAM1 for the nuclear imaging of atherosclerotic lesions.

Broisat A, Hernot S, Toczek J, De Vos J, Riou LM, Martin S, Ahmadi M, Thielens N, Wernery U, Caveliers V, Muyldermans S, Lahoutte T, Fagret D, Ghezzi C, Devoogdt N.

Circ Res. 2012 Mar 30;110(7):927-37. doi: 10.1161/CIRCRESAHA.112.265140.


Reduction of renal uptake of 111In-DOTA-labeled and A700-labeled RAFT-RGD during integrin αvβ3 targeting using single photon emission computed tomography and optical imaging.

Briat A, Wenk CH, Ahmadi M, Claron M, Boturyn D, Josserand V, Dumy P, Fagret D, Coll JL, Ghezzi C, Sancey L, Vuillez JP.

Cancer Sci. 2012 Jun;103(6):1105-10. doi: 10.1111/j.1349-7006.2012.02286.x. Epub 2012 Apr 23.


In vivo molecular imaging of myocardial angiogenesis using the alpha(v)beta3 integrin-targeted tracer 99mTc-RAFT-RGD.

Dimastromatteo J, Riou LM, Ahmadi M, Pons G, Pellegrini E, Broisat A, Sancey L, Gavrilina T, Boturyn D, Dumy P, Fagret D, Ghezzi C.

J Nucl Cardiol. 2010 Jun;17(3):435-43. doi: 10.1007/s12350-010-9191-9. Epub 2010 Jan 20.


Pre-clinical and clinical evaluation of nuclear tracers for the molecular imaging of vulnerable atherosclerosis: an overview.

Riou LM, Broisat A, Dimastromatteo J, Pons G, Fagret D, Ghezzi C.

Curr Med Chem. 2009;16(12):1499-511. Review.


Can the sentinel lymph node technique affect decisions to offer internal mammary chain irradiation?

Bourre JC, Payan R, Collomb D, Gallazzini-Crepin C, Calizzano A, Desruet MD, Pasquier D, Bolla M, Fagret D, Vuillez JP.

Eur J Nucl Med Mol Imaging. 2009 May;36(5):758-64. doi: 10.1007/s00259-008-1034-4. Epub 2009 Jan 14.


Chemical and biological evaluations of an (111)in-labeled RGD-peptide targeting integrin alpha(V) beta(3) in a preclinical tumor model.

Ahmadi M, Sancey L, Briat A, Riou L, Boturyn D, Dumy P, Fagret D, Ghezzi C, Vuillez JP.

Cancer Biother Radiopharm. 2008 Dec;23(6):691-700. doi: 10.1089/cbr.2008.0528.


First human treatment of resistant neoplastic meningitis by intrathecal administration of MTX plus (125)IUdR.

Rebischung C, Hoffmann D, Stefani L, Desruet MD, Wang K, Adelstein SJ, Artignan X, Vincent F, Gauchez AS, Zhang H, Fagret D, Vuillez J, Kassis AI, Balosso J.

Int J Radiat Biol. 2008 Dec;84(12):1123-9. doi: 10.1080/09553000802395535.


Acute and chronic effects of citalopram on 5-HT1A receptor-labeling by [18F]MPPF and -coupling to receptors-G proteins.

Moulin-Sallanon M, Charnay Y, Ginovart N, Perret P, Lanfumey L, Hamon M, Hen R, Fagret D, Ibáñez V, Millet P.

Synapse. 2009 Feb;63(2):106-16. doi: 10.1002/syn.20588.


In vivo quantification of 5-HT1A-[18F]MPPF interactions in rats using the YAP-(S)PET scanner and a beta-microprobe.

Millet P, Moulin M, Bartoli A, Del Guerra A, Ginovart N, Lemoucheux L, Buono S, Fagret D, Charnay Y, Ibáñez V.

Neuroimage. 2008 Jul 1;41(3):823-34. doi: 10.1016/j.neuroimage.2008.02.062. Epub 2008 Mar 14.


[Study of a detection strategy for silent ischemia in diabetic patients: 18 month follow-up of the ARCADIA register].

Vanzetto G, Halimi S, Ormezzano O, Steidel J, Belle L, Boizel R, Fagret D, Machecourt J.

Arch Mal Coeur Vaiss. 2007 Oct;100(10):845-52. French.


N-terminal pro-brain natriuretic peptide predicts myocardial ischemia and is related to postischemic left-ventricular dysfunction in patients with stable coronary artery disease.

Vanzetto G, Jacon P, Calizzano A, Neuder Y, Faure P, Fagret D, Machecourt J.

J Nucl Cardiol. 2007 Nov-Dec;14(6):835-42. Epub 2007 Oct 18.


Effects of a myocardial ischaemia-guided therapeutic program on survival and incidence of coronary events in asymptomatic patients with diabetes: the ARCADIA study.

Vanzetto G, Boizel R, Halimi S, Ormezzano O, Belle L, Fagret D, Machecourt J.

Diabetes Metab. 2007 Dec;33(6):459-65. Epub 2007 Oct 30.


In vivo imaging of tumour angiogenesis in mice with the alpha(v)beta (3) integrin-targeted tracer 99mTc-RAFT-RGD.

Sancey L, Ardisson V, Riou LM, Ahmadi M, Marti-Batlle D, Boturyn D, Dumy P, Fagret D, Ghezzi C, Vuillez JP.

Eur J Nucl Med Mol Imaging. 2007 Dec;34(12):2037-47. Epub 2007 Aug 4.


In vivo assessment of cardiac insulin resistance by nuclear probes using an iodinated tracer of glucose transport.

Briat A, Slimani L, Perret P, Villemain D, Halimi S, Demongeot J, Fagret D, Ghezzi C.

Eur J Nucl Med Mol Imaging. 2007 Nov;34(11):1756-64. Epub 2007 May 26.


Molecular imaging of vascular cell adhesion molecule-1 expression in experimental atherosclerotic plaques with radiolabelled B2702-p.

Broisat A, Riou LM, Ardisson V, Boturyn D, Dumy P, Fagret D, Ghezzi C.

Eur J Nucl Med Mol Imaging. 2007 Jun;34(6):830-40. Epub 2007 Jan 12.


SPECT imaging, immunohistochemical and behavioural correlations in the primate models of Parkinson's disease.

Ashkan K, Wallace BA, Mitrofanis J, Pollo C, Brard PY, Fagret D, Benabid AL.

Parkinsonism Relat Disord. 2007 Jul;13(5):266-75. Epub 2006 Dec 29.


Assessment of insulin resistance in fructose-fed rats with 125I-6-deoxy-6-iodo-D-glucose, a new tracer of glucose transport.

Perret P, Slimani L, Briat A, Villemain D, Halimi S, Demongeot J, Fagret D, Ghezzi C.

Eur J Nucl Med Mol Imaging. 2007 May;34(5):734-744. doi: 10.1007/s00259-006-0267-3. Epub 2006 Dec 15.


Assessment of non-reperfused and reperfused myocardial infarction using diffusible or deposited radiolabelled perfusion imaging agents.

Riou LM, Broisat A, Lartizien C, Toufektsian MC, Maitrejean S, Janier M, Vanzetto G, Fagret D, Ghezzi C.

Eur J Nucl Med Mol Imaging. 2007 Mar;34(3):330-7. Epub 2006 Sep 27.


Prospect for anti-her2 receptor therapy in breast cancer.

Brand FX, Ravanel N, Gauchez AS, Pasquier D, Payan R, Fagret D, Mousseau M.

Anticancer Res. 2006 Jan-Feb;26(1B):715-22. Review.


Prospect for anti-HER2 receptor therapy in breast cancer.

Brand FX, Ravanel N, Gauchez AS, Pasquier D, Payan R, Fagret D, Mousseau M.

Anticancer Res. 2006 Jan-Feb;26(1B):463-70. Review.

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