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Items: 12

1.

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.

Vianello P, Sartori L, Amigoni F, Cappa A, Fagá G, Fattori R, Legnaghi E, Ciossani G, Mattevi A, Meroni G, Moretti L, Cecatiello V, Pasqualato S, Romussi A, Thaler F, Trifiró P, Villa M, Botrugno OA, Dessanti P, Minucci S, Vultaggio S, Zagarrí E, Varasi M, Mercurio C.

J Med Chem. 2017 Mar 9;60(5):1693-1715. doi: 10.1021/acs.jmedchem.6b01019. Epub 2017 Feb 27.

PMID:
28186757
2.

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.

Sartori L, Mercurio C, Amigoni F, Cappa A, Fagá G, Fattori R, Legnaghi E, Ciossani G, Mattevi A, Meroni G, Moretti L, Cecatiello V, Pasqualato S, Romussi A, Thaler F, Trifiró P, Villa M, Vultaggio S, Botrugno OA, Dessanti P, Minucci S, Zagarrí E, Carettoni D, Iuzzolino L, Varasi M, Vianello P.

J Med Chem. 2017 Mar 9;60(5):1673-1692. doi: 10.1021/acs.jmedchem.6b01018. Epub 2017 Feb 27.

PMID:
28186755
3.

Selective transcriptional regulation by Myc in cellular growth control and lymphomagenesis.

Sabò A, Kress TR, Pelizzola M, de Pretis S, Gorski MM, Tesi A, Morelli MJ, Bora P, Doni M, Verrecchia A, Tonelli C, Fagà G, Bianchi V, Ronchi A, Low D, Müller H, Guccione E, Campaner S, Amati B.

Nature. 2014 Jul 24;511(7510):488-492. doi: 10.1038/nature13537. Epub 2014 Jul 9.

4.

Dual regulation of Myc by Abl.

Sanchez-Arévalo Lobo VJ, Doni M, Verrecchia A, Sanulli S, Fagà G, Piontini A, Bianchi M, Conacci-Sorrell M, Mazzarol G, Peg V, Losa JH, Ronchi P, Ponzoni M, Eisenman RN, Doglioni C, Amati B.

Oncogene. 2013 Nov 7;32(45):5261-71. doi: 10.1038/onc.2012.621. Epub 2013 Jan 14.

5.

Genome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts.

Perna D, Fagà G, Verrecchia A, Gorski MM, Barozzi I, Narang V, Khng J, Lim KC, Sung WK, Sanges R, Stupka E, Oskarsson T, Trumpp A, Wei CL, Müller H, Amati B.

Oncogene. 2012 Mar 29;31(13):1695-709. doi: 10.1038/onc.2011.359. Epub 2011 Aug 22.

6.

TGFβ-dependent gene expression shows that senescence correlates with abortive differentiation along several lineages in Myc-induced lymphomas.

Müller J, Samans B, van Riggelen J, Fagà G, Peh K N R, Wei CL, Müller H, Amati B, Felsher D, Eilers M.

Cell Cycle. 2010 Dec 1;9(23):4622-6.

PMID:
21127397
7.

Myc, Cdk2 and cellular senescence: Old players, new game.

Campaner S, Doni M, Verrecchia A, Fagà G, Bianchi L, Amati B.

Cell Cycle. 2010 Sep 15;9(18):3655-61. Epub 2010 Sep 15.

PMID:
20818171
8.

A positive role for Myc in TGFbeta-induced Snail transcription and epithelial-to-mesenchymal transition.

Smith AP, Verrecchia A, Fagà G, Doni M, Perna D, Martinato F, Guccione E, Amati B.

Oncogene. 2009 Jan 22;28(3):422-30. doi: 10.1038/onc.2008.395. Epub 2008 Nov 3.

PMID:
18978814
9.

Detection of minimal residual disease by real-time PCR can be used as a surrogate marker to evaluate the graft-versus-myeloma effect after allogeneic stem cell transplantation.

Voena C, Malnati M, Majolino I, Fagà G, Montefusco V, Farina L, Santoro A, Ladetto M, Boccadoro M, Corradini P.

Bone Marrow Transplant. 2003 Oct;32(8):791-3.

PMID:
14520423
10.

Pathogenic effects of human herpesvirus 6 in human lymphoid tissue ex vivo.

Grivel JC, Santoro F, Chen S, Fagá G, Malnati MS, Ito Y, Margolis L, Lusso P.

J Virol. 2003 Aug;77(15):8280-9.

11.

Suppression of CCR5- but not CXCR4-tropic HIV-1 in lymphoid tissue by human herpesvirus 6.

Grivel JC, Ito Y, Fagà G, Santoro F, Shaheen F, Malnati MS, Fitzgerald W, Lusso P, Margolis L.

Nat Med. 2001 Nov;7(11):1232-5.

PMID:
11689888
12.

Development of reverse transcriptase PCR assays for detection of active human herpesvirus 6 infection.

Van den Bosch G, Locatelli G, Geerts L, Fagà G, Ieven M, Goossens H, Bottiger D, Oberg B, Lusso P, Berneman ZN.

J Clin Microbiol. 2001 Jun;39(6):2308-10.

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