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Items: 16

1.

Elucidation of protein interactions necessary for the maintenance of the BCR-ABL signaling complex.

Gregor T, Bosakova MK, Nita A, Abraham SP, Fafilek B, Cernohorsky NH, Rynes J, Foldynova-Trantirkova S, Zackova D, Mayer J, Trantirek L, Krejci P.

Cell Mol Life Sci. 2019 Dec 9. doi: 10.1007/s00018-019-03397-7. [Epub ahead of print]

PMID:
31820037
2.

Phosphoinositide 5-phosphatases SKIP and SHIP2 in ruffles, the endoplasmic reticulum and the nucleus: An update.

Ramos AR, Ghosh S, Suhel T, Chevalier C, Obeng EO, Fafilek B, Krejci P, Beck B, Erneux C.

Adv Biol Regul. 2020 Jan;75:100660. doi: 10.1016/j.jbior.2019.100660. Epub 2019 Oct 7.

PMID:
31628071
3.

Fibroblast growth factor receptor influences primary cilium length through an interaction with intestinal cell kinase.

Kunova Bosakova M, Nita A, Gregor T, Varecha M, Gudernova I, Fafilek B, Barta T, Basheer N, Abraham SP, Balek L, Tomanova M, Fialova Kucerova J, Bosak J, Potesil D, Zieba J, Song J, Konik P, Park S, Duran I, Zdrahal Z, Smajs D, Jansen G, Fu Z, Ko HW, Hampl A, Trantirek L, Krakow D, Krejci P.

Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4316-4325. doi: 10.1073/pnas.1800338116. Epub 2019 Feb 19.

4.

The inositol phosphatase SHIP2 enables sustained ERK activation downstream of FGF receptors by recruiting Src kinases.

Fafilek B, Balek L, Bosakova MK, Varecha M, Nita A, Gregor T, Gudernova I, Krenova J, Ghosh S, Piskacek M, Jonatova L, Cernohorsky NH, Zieba JT, Kostas M, Haugsten EM, Wesche J, Erneux C, Trantirek L, Krakow D, Krejci P.

Sci Signal. 2018 Sep 18;11(548). pii: eaap8608. doi: 10.1126/scisignal.aap8608.

PMID:
30228226
5.

Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480.

Gudernova I, Balek L, Varecha M, Kucerova JF, Kunova Bosakova M, Fafilek B, Palusova V, Uldrijan S, Trantirek L, Krejci P.

Oncotarget. 2017 Nov 27;8(65):109319-109331. doi: 10.18632/oncotarget.22674. eCollection 2017 Dec 12.

6.

Statins do not inhibit the FGFR signaling in chondrocytes.

Fafilek B, Hampl M, Ricankova N, Vesela I, Balek L, Kunova Bosakova M, Gudernova I, Varecha M, Buchtova M, Krejci P.

Osteoarthritis Cartilage. 2017 Sep;25(9):1522-1530. doi: 10.1016/j.joca.2017.05.014. Epub 2017 Jun 3.

7.

One reporter for in-cell activity profiling of majority of protein kinase oncogenes.

Gudernova I, Foldynova-Trantirkova S, Ghannamova BE, Fafilek B, Varecha M, Balek L, Hruba E, Jonatova L, Jelinkova I, Kunova Bosakova M, Trantirek L, Mayer J, Krejci P.

Elife. 2017 Feb 15;6. pii: e21536. doi: 10.7554/eLife.21536.

8.

Wnt Signaling Inhibition Deprives Small Intestinal Stem Cells of Clonogenic Capacity.

Janeckova L, Fafilek B, Krausova M, Horazna M, Vojtechova M, Alberich-Jorda M, Sloncova E, Galuskova K, Sedlacek R, Anderova M, Korinek V.

Genesis. 2016 Mar;54(3):101-14. doi: 10.1002/dvg.22922. Epub 2016 Feb 16.

9.

HIC1 Tumor Suppressor Loss Potentiates TLR2/NF-κB Signaling and Promotes Tissue Damage-Associated Tumorigenesis.

Janeckova L, Pospichalova V, Fafilek B, Vojtechova M, Tureckova J, Dobes J, Dubuissez M, Leprince D, Baloghova N, Horazna M, Hlavata A, Stancikova J, Sloncova E, Galuskova K, Strnad H, Korinek V.

Mol Cancer Res. 2015 Jul;13(7):1139-48. doi: 10.1158/1541-7786.MCR-15-0033. Epub 2015 May 1.

10.

NKD1 marks intestinal and liver tumors linked to aberrant Wnt signaling.

Stancikova J, Krausova M, Kolar M, Fafilek B, Svec J, Sedlacek R, Neroldova M, Dobes J, Horazna M, Janeckova L, Vojtechova M, Oliverius M, Jirsa M, Korinek V.

Cell Signal. 2015 Feb;27(2):245-56. doi: 10.1016/j.cellsig.2014.11.008. Epub 2014 Nov 14.

11.

Expression of the chicken GDNF family receptor α-1 as a marker of spermatogonial stem cells.

Mucksová J, Kalina J, Bakst M, Yan H, Brillard JP, Benešová B, Fafílek B, Hejnar J, Trefil P.

Anim Reprod Sci. 2013 Nov 1;142(1-2):75-83. doi: 10.1016/j.anireprosci.2013.08.006. Epub 2013 Sep 4.

PMID:
24060137
12.

Troy, a tumor necrosis factor receptor family member, interacts with lgr5 to inhibit wnt signaling in intestinal stem cells.

Fafilek B, Krausova M, Vojtechova M, Pospichalova V, Tumova L, Sloncova E, Huranova M, Stancikova J, Hlavata A, Svec J, Sedlacek R, Luksan O, Oliverius M, Voska L, Jirsa M, Paces J, Kolar M, Krivjanska M, Klimesova K, Tlaskalova-Hogenova H, Korinek V.

Gastroenterology. 2013 Feb;144(2):381-91. doi: 10.1053/j.gastro.2012.10.048. Epub 2012 Nov 7.

PMID:
23142137
13.

Generation of two modified mouse alleles of the Hic1 tumor suppressor gene.

Pospichalova V, Tureckova J, Fafilek B, Vojtechova M, Krausova M, Lukas J, Sloncova E, Takacova S, Divoky V, Leprince D, Plachy J, Korinek V.

Genesis. 2011 Mar;49(3):142-51. doi: 10.1002/dvg.20719.

PMID:
21309068
14.

Fatty acid modification of Wnt1 and Wnt3a at serine is prerequisite for lipidation at cysteine and is essential for Wnt signalling.

Doubravska L, Krausova M, Gradl D, Vojtechova M, Tumova L, Lukas J, Valenta T, Pospichalova V, Fafilek B, Plachy J, Sebesta O, Korinek V.

Cell Signal. 2011 May;23(5):837-48. doi: 10.1016/j.cellsig.2011.01.007. Epub 2011 Jan 16.

PMID:
21244856
15.

Dazap2 modulates transcription driven by the Wnt effector TCF-4.

Lukas J, Mazna P, Valenta T, Doubravska L, Pospichalova V, Vojtechova M, Fafilek B, Ivanek R, Plachy J, Novak J, Korinek V.

Nucleic Acids Res. 2009 May;37(9):3007-20. doi: 10.1093/nar/gkp179. Epub 2009 Mar 20.

16.

HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies.

Valenta T, Lukas J, Doubravska L, Fafilek B, Korinek V.

EMBO J. 2006 Jun 7;25(11):2326-37. Epub 2006 May 25.

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