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Items: 49

1.

Functional Analysis of Somatic Mutations Affecting Receptor Tyrosine Kinase Family in Metastatic Colorectal Cancer.

Duplaquet L, Figeac M, Leprêtre F, Frandemiche C, Villenet C, Sebda S, Sarafan-Vasseur N, Bénozène M, Vinchent A, Goormachtigh G, Wicquart L, Rousseau N, Beaussire L, Truant S, Michel P, Sabourin JC, Galateau-Sallé F, Copin MC, Zalcman G, De Launoit Y, Fafeur V, Tulasne D.

Mol Cancer Ther. 2019 Jun;18(6):1137-1148. doi: 10.1158/1535-7163.MCT-18-0582. Epub 2019 Mar 29.

PMID:
30926633
2.

Thiocarbamate-linked polysulfonate-peptide conjugates as selective hepatocyte growth factor receptor binders.

Besret S, Vicogne J, Dahmani F, Fafeur V, Desmet R, Drobecq H, Romieu A, Melnyk P, Melnyk O.

Bioconjug Chem. 2014 May 21;25(5):1000-10. doi: 10.1021/bc500137j. Epub 2014 May 5.

3.

LMP1-induced cell death may contribute to the emergency of its oncogenic property.

Brocqueville G, Ndour PA, Ouk TS, Le Goff A, De Witte C, Mougel A, Coll J, Fafeur V, Le Bourhis X, Adriaenssens E.

PLoS One. 2013 Apr 23;8(4):e60743. doi: 10.1371/journal.pone.0060743. Print 2013.

4.

Anti-apoptotic role of caspase-cleaved GAB1 adaptor protein in hepatocyte growth factor/scatter factor-MET receptor protein signaling.

Le Goff A, Ji Z, Leclercq B, Bourette RP, Mougel A, Guerardel C, de Launoit Y, Vicogne J, Goormachtigh G, Fafeur V.

J Biol Chem. 2012 Oct 12;287(42):35382-96. doi: 10.1074/jbc.M112.409797. Epub 2012 Aug 22.

5.

Inhibition of latent membrane protein 1 impairs the growth and tumorigenesis of latency II Epstein-Barr virus-transformed T cells.

Ndour PA, Brocqueville G, Ouk TS, Goormachtigh G, Morales O, Mougel A, Bertout J, Melnyk O, Fafeur V, Feuillard J, Coll J, Adriaenssens E.

J Virol. 2012 Apr;86(7):3934-43. doi: 10.1128/JVI.05747-11. Epub 2012 Jan 18.

6.

A one-pot three-segment ligation strategy for protein chemical synthesis.

Ollivier N, Vicogne J, Vallin A, Drobecq H, Desmet R, El Mahdi O, Leclercq B, Goormachtigh G, Fafeur V, Melnyk O.

Angew Chem Int Ed Engl. 2012 Jan 2;51(1):209-13. doi: 10.1002/anie.201105837. Epub 2011 Nov 16. No abstract available.

PMID:
22095761
7.

Polysaccharide microarrays: application to the identification of heparan sulphate mimetics.

Dheur J, Dendane N, Desmet R, Dahmani F, Goormachtigh G, Vicogne J, Fafeur V, Melnyk O.

Methods Mol Biol. 2012;808:231-40. doi: 10.1007/978-1-61779-373-8_16.

PMID:
22057529
8.

Degradation of the GAB1 adaptor by the ubiquitin-proteasome pathway hampers HGF/SF-MET signaling.

Goormachtigh G, Ji Z, Le Goff A, Fafeur V.

Biochem Biophys Res Commun. 2011 Aug 12;411(4):780-5. doi: 10.1016/j.bbrc.2011.07.024. Epub 2011 Jul 18.

PMID:
21782801
9.

PASE: a web-based platform for peptide/protein microarray experiments.

Pamelard F, Even G, Apostol C, Preda C, Dhaenens C, Fafeur V, Desmet R, Melnyk O.

Methods Mol Biol. 2009;570:413-30. doi: 10.1007/978-1-60327-394-7_24. Review.

PMID:
19649610
10.

Phosphorylation of the MET receptor on juxtamembrane tyrosine residue 1001 inhibits its caspase-dependent cleavage.

Deheuninck J, Goormachtigh G, Foveau B, Ji Z, Leroy C, Ancot F, Villeret V, Tulasne D, Fafeur V.

Cell Signal. 2009 Sep;21(9):1455-63. doi: 10.1016/j.cellsig.2009.05.005. Epub 2009 May 18.

PMID:
19450681
11.

Down-regulation of the met receptor tyrosine kinase by presenilin-dependent regulated intramembrane proteolysis.

Foveau B, Ancot F, Leroy C, Petrelli A, Reiss K, Vingtdeux V, Giordano S, Fafeur V, Tulasne D.

Mol Biol Cell. 2009 May;20(9):2495-507. doi: 10.1091/mbc.E08-09-0969. Epub 2009 Mar 18.

12.

Dominant-negative inhibition of Ets 1 suppresses tumor growth, invasion and migration in rat C6 glioma cells and reveals differentially expressed Ets 1 target genes.

Sahin A, Vercamer C, Kaminski A, Fuchs T, Florin A, Hahne JC, Mattot V, Pourtier-Manzanedo A, Pietsch T, Fafeur V, Wernert N.

Int J Oncol. 2009 Feb;34(2):377-89.

PMID:
19148472
13.

The transcription factor ETS-1: its role in tumour development and strategies for its inhibition.

Hahne JC, Okuducu AF, Sahin A, Fafeur V, Kiriakidis S, Wernert N.

Mini Rev Med Chem. 2008 Oct;8(11):1095-105. Review.

PMID:
18855726
14.

Caspase cleavage of the MET receptor generates an HGF interfering fragment.

Deheuninck J, Foveau B, Goormachtigh G, Leroy C, Ji Z, Tulasne D, Fafeur V.

Biochem Biophys Res Commun. 2008 Mar 14;367(3):573-7. doi: 10.1016/j.bbrc.2007.12.177. Epub 2008 Jan 8.

PMID:
18187039
15.

Molecular cloning and characterisation of SmSLK, a novel Ste20-like kinase in Schistosoma mansoni.

Yan Y, Tulasne D, Browaeys E, Cailliau K, Khayath N, Pierce RJ, Trolet J, Fafeur V, Ben Younes A, Dissous C.

Int J Parasitol. 2007 Dec;37(14):1539-50. Epub 2007 Jun 21.

PMID:
17651740
16.

HGF/SF regulates expression of apoptotic genes in MCF-10A human mammary epithelial cells.

Leroy C, Deheuninck J, Reveneau S, Foveau B, Ji Z, Villenet C, Quief S, Tulasne D, Kerckaert JP, Fafeur V.

Ann N Y Acad Sci. 2006 Dec;1090:188-202.

PMID:
17384262
17.

Amplification of apoptosis through sequential caspase cleavage of the MET tyrosine kinase receptor.

Foveau B, Leroy C, Ancot F, Deheuninck J, Ji Z, Fafeur V, Tulasne D.

Cell Death Differ. 2007 Apr;14(4):752-64. Epub 2006 Dec 22.

18.

Regulation of the Ets-1 transcription factor by sumoylation and ubiquitinylation.

Ji Z, Degerny C, Vintonenko N, Deheuninck J, Foveau B, Leroy C, Coll J, Tulasne D, Baert JL, Fafeur V.

Oncogene. 2007 Jan 18;26(3):395-406. Epub 2006 Jul 24.

PMID:
16862185
19.

Autoactivation of the Epstein-Barr virus oncogenic protein LMP1 during type II latency through opposite roles of the NF-kappaB and JNK signaling pathways.

Goormachtigh G, Ouk TS, Mougel A, Tranchand-Bunel D, Masy E, Le Clorennec C, Feuillard J, Bornkamm GW, Auriault C, Manet E, Fafeur V, Adriaenssens E, Coll J.

J Virol. 2006 Aug;80(15):7382-93.

20.

ERK2 is required for FGF1-induced JNK1 phosphorylation in Xenopus oocyte expressing FGF receptor 1.

Browaeys-Poly E, Fafeur V, Vilain JP, Cailliau K.

Biochim Biophys Acta. 2005 Mar 22;1743(1-2):1-4.

21.

Proapoptotic function of the MET tyrosine kinase receptor through caspase cleavage.

Tulasne D, Deheuninck J, Lourenco FC, Lamballe F, Ji Z, Leroy C, Puchois E, Moumen A, Maina F, Mehlen P, Fafeur V.

Mol Cell Biol. 2004 Dec;24(23):10328-39.

22.

Conservation of epidermal growth factor receptor function in the human parasitic helminth Schistosoma mansoni.

Vicogne J, Cailliau K, Tulasne D, Browaeys E, Yan YT, Fafeur V, Vilain JP, Legrand D, Trolet J, Dissous C.

J Biol Chem. 2004 Sep 3;279(36):37407-14. Epub 2004 Jun 30.

23.

Inhibition of JNK by HGF/SF prevents apoptosis induced by TNF-alpha.

Reveneau S, Paumelle R, Deheuninck J, Leroy C, De Launoit Y, Fafeur V.

Ann N Y Acad Sci. 2003 Dec;1010:100-3.

PMID:
15033702
24.

A novel dominant-negative mutant form of Epstein-Barr virus latent membrane protein-1 (LMP1) selectively and differentially impairs LMP1 and TNF signaling pathways.

Adriaenssens E, Mougel A, Goormachtigh G, Loing E, Fafeur V, Auriault C, Coll J.

Oncogene. 2004 Apr 8;23(15):2681-93. Erratum in: Oncogene. 2004 Oct 21;23(49):8184.

PMID:
14767477
25.

Involvement of RAS-ERK signaling in multiple biological responses to HGF/SF.

Tulasne D, Paumelle R, Leroy C, Reveneau S, Vandenbunder B, Fafeur V.

Ann N Y Acad Sci. 2002 Nov;973:105-8. No abstract available.

PMID:
12485843
26.

Cross-talk between mesenchyme and epithelium increases H19 gene expression during scattering and morphogenesis of epithelial cells.

Adriaenssens E, Lottin S, Berteaux N, Hornez L, Fauquette W, Fafeur V, Peyrat JP, Le Bourhis X, Hondermarck H, Coll J, Dugimont T, Curgy JJ.

Exp Cell Res. 2002 May 1;275(2):215-29.

PMID:
11969291
27.

Hepatocyte growth factor/scatter factor activates the ETS1 transcription factor by a RAS-RAF-MEK-ERK signaling pathway.

Paumelle R, Tulasne D, Kherrouche Z, Plaza S, Leroy C, Reveneau S, Vandenbunder B, Fafeur V.

Oncogene. 2002 Apr 4;21(15):2309-19. Erratum in: Oncogene 2002 Jul 18;21(31):4872. Tulashe, David [corrected to Tulasne, David]; Reveneau, Syline [corrected to Reveneau, Sylvie].

28.

The ERK-dependent signalling is stage-specifically modulated by FSH, during primary Sertoli cell maturation.

Crépieux P, Marion S, Martinat N, Fafeur V, Vern YL, Kerboeuf D, Guillou F, Reiter E.

Oncogene. 2001 Aug 2;20(34):4696-709.

29.

Sequential activation of ERK and repression of JNK by scatter factor/hepatocyte growth factor in madin-darby canine kidney epithelial cells.

Paumelle R, Tulasne D, Leroy C, Coll J, Vandenbunder B, Fafeur V.

Mol Biol Cell. 2000 Nov;11(11):3751-63.

30.

Development of an ultralow-light-level luminescence image analysis system for dynamic measurements of transcriptional activity in living and migrating cells.

Maire E, Lelièvre E, Brau D, Lyons A, Woodward M, Fafeur V, Vandenbunder B.

Anal Biochem. 2000 Apr 10;280(1):118-27.

PMID:
10805529
31.

Constitutive expression of the DNA-binding domain of Ets1 increases endothelial cell adhesion and stimulates their organization into capillary-like structures.

Mattot V, Vercamer C, Soncin F, Calmels T, Huguet C, Fafeur V, Vandenbunder B.

Oncogene. 2000 Feb 10;19(6):762-72.

32.

[Transcription factors of the Ets family and morphogenesis of the vascular tree].

Mattot V, Vercamer C, Soncin F, Fafeur V, Vandenbunder B.

J Soc Biol. 1999;193(2):147-53. Review. French.

PMID:
10451348
33.

[Transcription factors and angiogenesis].

Soncin F, Fafeur V, Vandenbunder B.

Pathol Biol (Paris). 1999 Apr;47(4):358-63. Review. French.

PMID:
10372405
34.

The multisubstrate docking site of the MET receptor is dispensable for MET-mediated RAS signaling and cell scattering.

Tulasne D, Paumelle R, Weidner KM, Vandenbunder B, Fafeur V.

Mol Biol Cell. 1999 Mar;10(3):551-65.

35.

The expression of an Ets1 transcription factor lacking its activation domain decreases uPA proteolytic activity and cell motility, and impairs normal tubulogenesis and cancerous scattering in mammary epithelial cells.

Delannoy-Courdent A, Mattot V, Fafeur V, Fauquette W, Pollet I, Calmels T, Vercamer C, Boilly B, Vandenbunder B, Desbiens X.

J Cell Sci. 1998 Jun;111 ( Pt 11):1521-34.

36.

The ETS1 transcription factor is expressed during epithelial-mesenchymal transitions in the chick embryo and is activated in scatter factor-stimulated MDCK epithelial cells.

Fafeur V, Tulasne D, Quéva C, Vercamer C, Dimster V, Mattot V, Stéhelin D, Desbiens X, Vandenbunder B.

Cell Growth Differ. 1997 Jun;8(6):655-65.

37.

The c-ets-1 proto-oncogene is a new early-response gene differentially regulated by cytokines and growth factors in human fibroblasts.

Gilles F, Raes MB, Stéhelin D, Vandenbunder B, Fafeur V.

Exp Cell Res. 1996 Feb 1;222(2):370-8.

PMID:
8598225
38.

Stromal expression of c-Ets1 transcription factor correlates with tumor invasion.

Wernert N, Gilles F, Fafeur V, Bouali F, Raes MB, Pyke C, Dupressoir T, Seitz G, Vandenbunder B, Stéhelin D.

Cancer Res. 1994 Nov 1;54(21):5683-8.

40.

Signal transduction by bFGF, but not TGF beta 1, involves arachidonic acid metabolism in endothelial cells.

Fafeur V, Jiang ZP, Böhlen P.

J Cell Physiol. 1991 Nov;149(2):277-83.

PMID:
1660902
41.

Isolation from bovine brain and structural characterization of HBNF, a heparin-binding neurotrophic factor.

Böhlen P, Müller T, Gautschi-Sova P, Albrecht U, Rasool CG, Decker M, Seddon A, Fafeur V, Kovesdi I, Kretschmer P.

Growth Factors. 1991;4(2):97-107.

PMID:
2049182
43.

Recent studies on icosanoids and PAF-acether modulation of some central neurosecretions in the rat.

Dray F, Gerozissis K, Fafeur V, Wisner A, Bommelaer-Bayet MC, Saadi M, Rougeot C, Tiberghien C, Junier MP.

Adv Prostaglandin Thromboxane Leukot Res. 1989;19:383-6. No abstract available.

PMID:
2546391
45.

12-Hydroperoxyeicosatetraenoic acid (12-HPETE) and 15-HPETE stimulate melatonin synthesis in rat pineals.

Sakai K, Fafeur V, Vulliez-le Normand B, Dray F.

Prostaglandins. 1988 Jun;35(6):969-76.

PMID:
3187058
46.
47.
48.

Immunological castration by a totally synthetic vaccine: modification of biological properties of LH-RH after conjugation to adjuvant-active muramyl peptide.

Carelli C, Ralamboranto L, Audibert F, Gaillard J, Briquelet N, Dray F, Fafeur V, Haour F, Chedid L.

Int J Immunopharmacol. 1985;7(2):215-24.

PMID:
3891644

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