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Diagnostic yield of commercial immunodots to diagnose paraneoplastic neurologic syndromes.

Déchelotte B, Muñiz-Castrillo S, Joubert B, Vogrig A, Picard G, Rogemond V, Pinto AL, Lombard C, Desestret V, Fabien N, Honnorat J.

Neurol Neuroimmunol Neuroinflamm. 2020 Mar 13;7(3). pii: e701. doi: 10.1212/NXI.0000000000000701. Print 2020 May.


Primary DQ effect in the association between HLA and neurological syndromes with anti-GAD65 antibodies.

Muñiz-Castrillo S, Ambati A, Dubois V, Vogrig A, Joubert B, Rogemond V, Picard G, Lin L, Fabien N, Mignot E, Honnorat J.

J Neurol. 2020 Mar 9. doi: 10.1007/s00415-020-09782-8. [Epub ahead of print]


Anti-MDA5 juvenile idiopathic inflammatory myopathy: a specific subgroup defined by differentially enhanced interferon-α signalling.

Melki I, Devilliers H, Gitiaux C, Bondet V, Duffy D, Charuel JL, Miyara M, Bokov P, Kheniche A, Kwon T, Authier FJ, Allenbach Y, Belot A, Bodemer C, Bourrat E, Dumaine C, Fabien N, Faye A, Frémond ML, Hadchouel A, Kitabayashi N, Lepelley A, Martin-Niclos MJ, Mudumba S, Musset L, Quartier P, Rice GI, Seabra L, Uettwiller F, Uggenti C, Viel S, Rodero MP, Crow YJ, Bader-Meunier B.

Rheumatology (Oxford). 2019 Nov 22. pii: kez525. doi: 10.1093/rheumatology/kez525. [Epub ahead of print]


GAPDH Overexpression in the T Cell Lineage Promotes Angioimmunoblastic T Cell Lymphoma through an NF-κB-Dependent Mechanism.

Mondragón L, Mhaidly R, De Donatis GM, Tosolini M, Dao P, Martin AR, Pons C, Chiche J, Jacquin M, Imbert V, Proïcs E, Boyer L, Doye A, Luciano F, Neels JG, Coutant F, Fabien N, Sormani L, Rubio-Patiño C, Bossowski JP, Muller F, Marchetti S, Villa E, Peyron JF, Gaulard P, Lemonnier F, Asnafi V, Genestier L, Benhida R, Fournié JJ, Passeron T, Ricci JE, Verhoeyen E.

Cancer Cell. 2019 Sep 16;36(3):268-287.e10. doi: 10.1016/j.ccell.2019.07.008. Epub 2019 Aug 22.


The multifaceted nature of diabetes mellitus induced by checkpoint inhibitors.

Marchand L, Disse E, Dalle S, Reffet S, Vouillarmet J, Fabien N, Thivolet C, Cugnet-Anceau C.

Acta Diabetol. 2019 Dec;56(12):1239-1245. doi: 10.1007/s00592-019-01402-w. Epub 2019 Aug 19. Review.


The IgG2 Isotype of Anti-Transcription Intermediary Factor 1γ Autoantibodies Is a Biomarker of Cancer and Mortality in Adult Dermatomyositis.

Aussy A, Fréret M, Gallay L, Bessis D, Vincent T, Jullien D, Drouot L, Jouen F, Joly P, Marie I, Meyer A, Sibilia J, Bader-Meunier B, Hachulla E, Hamidou M, Huë S, Charuel JL, Fabien N, Viailly PJ, Allenbach Y, Benveniste O, Cordel N, Boyer O; OncoMyositis Study Group.

Arthritis Rheumatol. 2019 Aug;71(8):1360-1370. doi: 10.1002/art.40895. Epub 2019 Jul 8.


TRIM9 and TRIM67 Are New Targets in Paraneoplastic Cerebellar Degeneration.

Do LD, Gupton SL, Tanji K, Bastien J, Brugière S, Couté Y, Quadrio I, Rogemond V, Fabien N, Desestret V, Honnorat J.

Cerebellum. 2019 Apr;18(2):245-254. doi: 10.1007/s12311-018-0987-5.


Diabetes mellitus induced by PD-1 and PD-L1 inhibitors: description of pancreatic endocrine and exocrine phenotype.

Marchand L, Thivolet A, Dalle S, Chikh K, Reffet S, Vouillarmet J, Fabien N, Cugnet-Anceau C, Thivolet C.

Acta Diabetol. 2019 Apr;56(4):441-448. doi: 10.1007/s00592-018-1234-8. Epub 2018 Oct 4.


Very high titres of ZnT8 autoantibodies at type 1 diabetes onset and presence of autoantibodies related to other autoimmune disorders.

Marchand L, Garnier L, Thivolet C, Nicolino M, Fabien N.

Diabetes Metab. 2020 Feb;46(1):73-74. doi: 10.1016/j.diabet.2018.03.003. Epub 2018 Mar 22. No abstract available.


Research and identification of antinuclear antibodies: analysis of a questionnaire from the European EASI group and confrontation of French practices to international recommendations.

Musset L, Fabien N, Chyderiotis G, Olsson NO, Pham BN, Durey Dragon MA.

Ann Biol Clin (Paris). 2018 Apr 1;76(2):185-195. doi: 10.1684/abc.2018.1328.


Nivolumab-induced myositis: A case report and a literature review.

Bourgeois-Vionnet J, Joubert B, Bernard E, Sia MA, Pante V, Fabien N, Honnorat J, Streichenberger N.

J Neurol Sci. 2018 Apr 15;387:51-53. doi: 10.1016/j.jns.2018.01.030. Epub 2018 Feb 3. Review. No abstract available.


Anti-Programmed Death 1 (PD-1) Antibodies and the Pancreas: A Diabetic Storm Ahead?

Marchand L, Thivolet A, Saintigny P, Fabien N, Vouillarmet J, Thivolet C.

Diabetes Care. 2018 Mar;41(3):638-639. doi: 10.2337/dc17-2243. No abstract available.


Multiplex family with GAD65-Abs neurologic syndromes.

Belbezier A, Joubert B, Montero-Martin G, Fernandez-Vina M, Fabien N, Rogemond V, Mignot E, Honnorat J.

Neurol Neuroimmunol Neuroinflamm. 2017 Dec 5;5(1):e416. doi: 10.1212/NXI.0000000000000416. eCollection 2018 Jan.


Screening of ZnT8 autoantibodies in the diagnosis of autoimmune diabetes in a large French cohort.

Garnier L, Marchand L, Benoit M, Nicolino M, Bendelac N, Wright C, Moulin P, Lombard C, Thivolet C, Fabien N.

Clin Chim Acta. 2018 Mar;478:162-165. doi: 10.1016/j.cca.2017.12.043. Epub 2017 Dec 28.


Clinical, histological, immunological presentations and outcomes of bullous systemic lupus erythematosus: 10 New cases and a literature review of 118 cases.

de Risi-Pugliese T, Cohen Aubart F, Haroche J, Moguelet P, Grootenboer-Mignot S, Mathian A, Ingen-Housz-Oro S, Hie M, Wendremaire N, Aucouturier F, Lepelletier F, Miyara M, Bader-Meunier B, Rémy P, Fabien N, Francès C, Barete S, Amoura Z.

Semin Arthritis Rheum. 2018 Aug;48(1):83-89. doi: 10.1016/j.semarthrit.2017.11.003. Epub 2017 Nov 4.


Nivolumab-Induced Acute Diabetes Mellitus and Hypophysitis in a Patient with Advanced Pulmonary Pleomorphic Carcinoma with a Prolonged Tumor Response.

Marchand L, Paulus V, Fabien N, Pérol M, Thivolet C, Vouillarmet J, Saintigny P.

J Thorac Oncol. 2017 Nov;12(11):e182-e184. doi: 10.1016/j.jtho.2017.07.021. No abstract available.


Testing anti-neutrophil cytoplasmic antibodies (ANCA): analysis of the European EASI survey on the daily practice of the French laboratories.

Dragon-Durey MA, Fabien N, Chyderiotis G, Musset L, Pham BN, Olsson N.

Ann Biol Clin (Paris). 2017 Oct 1;75(5):531-541. doi: 10.1684/abc.2017.1273.


Comment on Jackson et al. Insulitis in Autoantibody-Positive Pancreatic Donor With History of Gestational Diabetes Mellitus. Diabetes Care 2017;40:723-725.

Marchand L, Garnier L, Fabien N, Thivolet C.

Diabetes Care. 2017 Oct;40(10):e155. doi: 10.2337/dc17-1044. No abstract available.


Isolated positive anti-SS-B autoantibodies are not related to clinical features of systemic autoimmune diseases: Results from a routine population survey.

Jardel S, Fabien N, Hot A, Vukusic S, Tebib J, Cottin V, Sève P, Laville M, Belot A, Durieu I, Garnier L, Coutant F, Reynaud Q, Lega JC.

PLoS One. 2017 Sep 20;12(9):e0185104. doi: 10.1371/journal.pone.0185104. eCollection 2017.


An international survey on anti-neutrophil cytoplasmic antibodies (ANCA) testing in daily clinical practice.

Damoiseaux J, Heijnen I, Van Campenhout C, Eriksson C, Fabien N, Herold M, van der Molen RG, Egner W, Patel D, Plaza-Lopez A, Radice A, de Sousa MJR, Viander M, Shoenfeld Y.

Clin Chem Lab Med. 2018 Sep 25;56(10):1759-1770. doi: 10.1515/cclm-2017-0306. No abstract available.


Chilblain lupus erythematosus treated successfully with mycophenolate mofetil.

Gouillon L, Debarbieux S, Berruyer M, Fabien N, Lega JC, Thomas L.

Int J Dermatol. 2017 Aug;56(8):e158-e159. doi: 10.1111/ijd.13614. Epub 2017 Mar 27. No abstract available.


Anti-C1q autoantibodies as markers of renal involvement in childhood-onset systemic lupus erythematosus.

Picard C, Lega JC, Ranchin B, Cochat P, Cabrera N, Fabien N, Belot A.

Pediatr Nephrol. 2017 Sep;32(9):1537-1545. doi: 10.1007/s00467-017-3646-z. Epub 2017 Mar 25.


Familial and syndromic lupus share the same phenotype as other early-onset forms of lupus.

Weill O, Decramer S, Malcus C, Kassai B, Rouvet I, Ginhoux T, Crow YJ, Rieux-Laucat F, Soulas-Sprauel P, Pagnier A, Koné-Paut I, Piram M, Galeotti C, Samaille C, Reumaux H, Lanteri A, Dubois SM, Lefebvre H, Burtey S, Maurier F, Carbasse A, Lemelle I, Meinzer U, Despert V, Flodrops H, Fabien N, Ranchin B, Hachulla E, Bader-Meunier B, Belot A.

Joint Bone Spine. 2017 Oct;84(5):589-593. doi: 10.1016/j.jbspin.2016.12.008. Epub 2016 Dec 28.


The Clinical Relevance of Antifibrillarin (anti-U3-RNP) Autoantibodies in Systemic Sclerosis.

Tall F, Dechomet M, Riviere S, Cottin V, Ballot E, Tiev KP, Montin R, Morin C, Chantran Y, Grange C, Jullien D, Ninet J, Chretien P, Cabane J, Fabien N, Johanet C.

Scand J Immunol. 2017 Jan;85(1):73-79. doi: 10.1111/sji.12510.


Current Status and New Perspectives on Chitin and Chitosan as Functional Biopolymers.

Philibert T, Lee BH, Fabien N.

Appl Biochem Biotechnol. 2017 Apr;181(4):1314-1337. doi: 10.1007/s12010-016-2286-2. Epub 2016 Oct 27. Review.


Tocilizumab in the treatment of mixed connective tissue disease and overlap syndrome in children.

Cabrera N, Duquesne A, Desjonquères M, Larbre JP, Lega JC, Fabien N, Belot A.

RMD Open. 2016 Sep 15;2(2):e000271. eCollection 2016.


Clinical association of mixed connective tissue disease and granulomatosis with polyangiitis: a case report and systematic screening of anti-U1RNP and anti-PR3 auto-antibody double positivity in ten European hospitals.

Tubery A, Fortenfant F, Combe B, Abreu I, Bossuyt X, Chretien P, Desplat-Jégo S, Fabien N, Hue S, Johanet C, Lakomy D, Vincent T, Daïen CI.

Immunol Res. 2016 Dec;64(5-6):1243-1246.


miRNA-375 a Sensor of Glucotoxicity Is Altered in the Serum of Children with Newly Diagnosed Type 1 Diabetes.

Marchand L, Jalabert A, Meugnier E, Van den Hende K, Fabien N, Nicolino M, Madec AM, Thivolet C, Rome S.

J Diabetes Res. 2016;2016:1869082. doi: 10.1155/2016/1869082. Epub 2016 May 24.


Heterogeneous clinical spectrum of anti-SRP myositis and importance of the methods of detection of anti-SRP autoantibodies: a multicentric study.

Picard C, Vincent T, Lega JC, Hue S, Fortenfant F, Lakomy D, Humbel RL, Goetz J, Molinari N, Bardin N, Bertin D, Johanet C, Chretien P, Dubucquoi S, Streichenberger N, Desplat-Jégo S, Bossuyt X, Sibilia J, Abreu I, Chevailler A, Fabien N.

Immunol Res. 2016 Jun;64(3):677-86. doi: 10.1007/s12026-015-8774-6.


Multiple autoantibodies at onset do not accurately predict long-term pancreatic beta-cell fate in a 13-year-old obese child with immediate insulin-requiring diabetes.

Marchand L, Nicolino M, Fabien N, Roep BO, Thivolet C.

Diabetes Metab. 2016 Feb;42(1):69-70. doi: 10.1016/j.diabet.2015.10.006. Epub 2015 Nov 24. No abstract available.


[Juvenile dermatomyositis and new autoantibodies: Cases and review].

Guarella M, Jurquet AL, Retornaz K, Bardin N, Chastang MC, Desjonquere M, Fabien N, Belot A.

Arch Pediatr. 2015 Dec;22(12):1263-7. doi: 10.1016/j.arcped.2015.09.007. Epub 2015 Nov 16. French.


Early-onset hypoparathyroidism and chronic keratitis revealing APECED.

Mezgueldi E, Bertholet-Thomas A, Milazzo S, Morris M, Bacchetta J, Fabien N, Cochat P, Weetman AP, Kemp EH, Belot A.

Clin Case Rep. 2015 Oct;3(10):809-13. doi: 10.1002/ccr3.354. Epub 2015 Aug 26.


Interstitial lung disease in an adult patient with dermatomyositis and anti-NXP2 autoantibody.

Gossez M, Levesque M, Khouatra C, Cottin V, Garnier L, Fabien N.

Eur Respir Rev. 2015 Jun;24(136):370-2. doi: 10.1183/16000617.00006714. No abstract available.


Idiopathic inflammatory myopathies and the lung.

Lega JC, Reynaud Q, Belot A, Fabien N, Durieu I, Cottin V.

Eur Respir Rev. 2015 Jun;24(136):216-38. doi: 10.1183/16000617.00002015. Review. Erratum in: Eur Respir Rev. 2015 Sep;24(137):545. Dosage error in article text.


Long-term disease course in a patient with severe neonatal IPEX syndrome.

Duclaux-Loras R, Collardeau-Frachon S, Nancey S, Fabien N, Kaiserlian D, Lachaux A.

Clin Res Hepatol Gastroenterol. 2015 Sep;39(4):e43-7. doi: 10.1016/j.clinre.2015.03.006. Epub 2015 May 11.


PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator-dependent autoimmunity.

Mathieu AL, Verronese E, Rice GI, Fouyssac F, Bertrand Y, Picard C, Chansel M, Walter JE, Notarangelo LD, Butte MJ, Nadeau KC, Csomos K, Chen DJ, Chen K, Delgado A, Rigal C, Bardin C, Schuetz C, Moshous D, Reumaux H, Plenat F, Phan A, Zabot MT, Balme B, Viel S, Bienvenu J, Cochat P, van der Burg M, Caux C, Kemp EH, Rouvet I, Malcus C, Méritet JF, Lim A, Crow YJ, Fabien N, Ménétrier-Caux C, De Villartay JP, Walzer T, Belot A.

J Allergy Clin Immunol. 2015 Jun;135(6):1578-88.e5. doi: 10.1016/j.jaci.2015.01.040. Epub 2015 Apr 2.


[Interstitial lung disease-associated with amyopathic dermatomyositis and anti-MDA5 autoantibodies].

Gerfaud-Valentin M, Ahmad K, Piegay F, Fabien N, Raphanel B, Cordier JF, Cottin V.

Rev Mal Respir. 2014 Nov;31(9):849-53. doi: 10.1016/j.rmr.2014.02.010. Epub 2014 Mar 18. French.


Mutations in CECR1 associated with a neutrophil signature in peripheral blood.

Belot A, Wassmer E, Twilt M, Lega JC, Zeef LA, Oojageer A, Kasher PR, Mathieu AL, Malcus C, Demaret J, Fabien N, Collardeau-Frachon S, Mechtouff L, Derex L, Walzer T, Rice GI, Durieu I, Crow YJ.

Pediatr Rheumatol Online J. 2014 Sep 24;12:44. doi: 10.1186/1546-0096-12-44. eCollection 2014.


Celiac disease diagnosis: impact of guidelines on medical prescription in France.

Pham BN, Musset L, Chyderiotis G, Olsson NO, Fabien N.

J Dig Dis. 2014 Aug;15(8):435-43. doi: 10.1111/1751-2980.12158.


The clinical phenotype associated with myositis-specific and associated autoantibodies: a meta-analysis revisiting the so-called antisynthetase syndrome.

Lega JC, Fabien N, Reynaud Q, Durieu I, Durupt S, Dutertre M, Cordier JF, Cottin V.

Autoimmun Rev. 2014 Sep;13(9):883-91. doi: 10.1016/j.autrev.2014.03.004. Epub 2014 Apr 3. Review.


Comparison of anti-CCP autoantibodies measurement by ELISA and a bead-based assay in a large patient cohort.

Harich R, Roger C, Garnier L, Bienvenu J, Fabien N.

Clin Biochem. 2014 Apr;47(6):485-8. doi: 10.1016/j.clinbiochem.2014.02.010. Epub 2014 Feb 19.


International recommendations for the assessment of autoantibodies to cellular antigens referred to as anti-nuclear antibodies.

Agmon-Levin N, Damoiseaux J, Kallenberg C, Sack U, Witte T, Herold M, Bossuyt X, Musset L, Cervera R, Plaza-Lopez A, Dias C, Sousa MJ, Radice A, Eriksson C, Hultgren O, Viander M, Khamashta M, Regenass S, Andrade LE, Wiik A, Tincani A, Rönnelid J, Bloch DB, Fritzler MJ, Chan EK, Garcia-De La Torre I, Konstantinov KN, Lahita R, Wilson M, Vainio O, Fabien N, Sinico RA, Meroni P, Shoenfeld Y.

Ann Rheum Dis. 2014 Jan;73(1):17-23. doi: 10.1136/annrheumdis-2013-203863. Epub 2013 Oct 14.


Protein kinase cδ deficiency causes mendelian systemic lupus erythematosus with B cell-defective apoptosis and hyperproliferation.

Belot A, Kasher PR, Trotter EW, Foray AP, Debaud AL, Rice GI, Szynkiewicz M, Zabot MT, Rouvet I, Bhaskar SS, Daly SB, Dickerson JE, Mayer J, O'Sullivan J, Juillard L, Urquhart JE, Fawdar S, Marusiak AA, Stephenson N, Waszkowycz B, W Beresford M, Biesecker LG, C M Black G, René C, Eliaou JF, Fabien N, Ranchin B, Cochat P, Gaffney PM, Rozenberg F, Lebon P, Malcus C, Crow YJ, Brognard J, Bonnefoy N.

Arthritis Rheum. 2013 Aug;65(8):2161-71. doi: 10.1002/art.38008.


A stepwise breakdown of B-cell tolerance occurs within renal allografts during chronic rejection.

Thaunat O, Graff-Dubois S, Fabien N, Duthey A, Attuil-Audenis V, Nicoletti A, Patey N, Morelon E.

Kidney Int. 2012 Jan;81(2):207-19. doi: 10.1038/ki.2011.317. Epub 2011 Sep 21.


Are immunoglobulin A anti-gliadin antibodies helpful in diagnosing coeliac disease in children younger than 2 years?

Foucher B, Johanet C, Jégo-Desplat S, Sanmarco M, Dubucquoi S, Fily-Nalewajk S, Olsson NO, Lakomy D, Escande A, Chrétien P, Fortenfant F, Chevailler A, André C, Goetz J, Humbel RL, Monier JC, Sibilia J, Taillefer MF, Abreu I, Fabien N.

J Pediatr Gastroenterol Nutr. 2012 Jan;54(1):110-2. doi: 10.1097/MPG.0b013e31823255c9.


[Adult celiac disease with thrombosis: a case series of seven patients. Role of thrombophilic factors].

Berthoux E, Fabien N, Chayvialle JA, Ninet J, Durieu I.

Rev Med Interne. 2011 Oct;32(10):600-4. doi: 10.1016/j.revmed.2011.02.025. Epub 2011 Mar 24. French.


[Rapidly progressive ANCA positive glomerulonephritis as the presenting feature of infectious endocarditis].

Hanf W, Serre JE, Salmon JH, Fabien N, Ginon I, Dijoud F, Trolliet P.

Rev Med Interne. 2011 Dec;32(12):e116-8. doi: 10.1016/j.revmed.2010.12.017. Epub 2011 Jan 31. French.


Gene expression profiling in peripheral blood cells of patients with rheumatoid arthritis in response to anti-TNF-alpha treatments.

Meugnier E, Coury F, Tebib J, Ferraro-Peyret C, Rome S, Bienvenu J, Vidal H, Sibilia J, Fabien N.

Physiol Genomics. 2011 Apr 12;43(7):365-71. doi: 10.1152/physiolgenomics.00127.2010. Epub 2011 Jan 25.


Esophageal dysmotility associated with systemic sclerosis: a high-resolution manometry study.

Roman S, Hot A, Fabien N, Cordier JF, Miossec P, Ninet J, Mion F; Réseau Sclérodermie des Hospices Civils de Lyon.

Dis Esophagus. 2011 Jul;24(5):299-304. doi: 10.1111/j.1442-2050.2010.01150.x. Epub 2010 Dec 17.


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