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Comment on: Evidence of innate lymphoid cell redundancy in humans.

Orange JS, Mace EM, French AR, Yokoyama WM, Fehniger TA, Cooper MA.

Nat Immunol. 2018 Jul 19. doi: 10.1038/s41590-018-0164-5. [Epub ahead of print] No abstract available.


Epidemiology and Outcomes of Granulomatosis with Polyangiitis (GPA) in Pediatric and Working-age Adults Populations in the United States: Analysis of a Large National Claims Database.

Panupattanapong S, Stwalley DL, White AJ, Olsen MA, French AR, Hartman ME.

Arthritis Rheumatol. 2018 May 27. doi: 10.1002/art.40577. [Epub ahead of print]


Glycolytic requirement for NK cell cytotoxicity and cytomegalovirus control.

Mah AY, Rashidi A, Keppel MP, Saucier N, Moore EK, Alinger JB, Tripathy SK, Agarwal SK, Jeng EK, Wong HC, Miller JS, Fehniger TA, Mace EM, French AR, Cooper MA.

JCI Insight. 2017 Dec 7;2(23). pii: 95128. doi: 10.1172/jci.insight.95128. [Epub ahead of print]


Serologic Evidence of Gut-driven Systemic Inflammation in Juvenile Idiopathic Arthritis.

Fotis L, Shaikh N, Baszis KW, Samson CM, Lev-Tzion R, French AR, Tarr PI.

J Rheumatol. 2017 Nov;44(11):1624-1631. doi: 10.3899/jrheum.161589. Epub 2017 Sep 15.


Investigations of human myosin VI targeting using optogenetically controlled cargo loading.

French AR, Sosnick TR, Rock RS.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):E1607-E1616. doi: 10.1073/pnas.1614716114. Epub 2017 Feb 13.


Deficiency of the adaptor protein SLy1 results in a natural killer cell ribosomopathy affecting tumor clearance.

Arefanian S, Schäll D, Chang S, Ghasemi R, Higashikubo R, Zheleznyak A, Guo Y, Yu J, Asgharian H, Li W, Gelman AE, Kreisel D, French AR, Zaher H, Plougastel-Douglas B, Maggi L, Yokoyama W, Beer-Hammer S, Krupnick AS.

Oncoimmunology. 2016 Sep 27;5(12):e1238543. doi: 10.1080/2162402X.2016.1238543. eCollection 2016.


Four Cases of Anti-PM/Scl Antibody-positive Juvenile Overlap Syndrome with Features of Myositis and Systemic Sclerosis.

Fotis L, Baszis KW, White AJ, French AR.

J Rheumatol. 2016 Sep;43(9):1768-9. doi: 10.3899/jrheum.151445. No abstract available.


Mesenteric vasculitis in children with systemic lupus erythematosus.

Fotis L, Baszis KW, French AR, Cooper MA, White AJ.

Clin Rheumatol. 2016 Mar;35(3):785-93. doi: 10.1007/s10067-015-2892-3. Epub 2015 Feb 17.


Type I interferons link viral infection to enhanced epithelial turnover and repair.

Sun L, Miyoshi H, Origanti S, Nice TJ, Barger AC, Manieri NA, Fogel LA, French AR, Piwnica-Worms D, Piwnica-Worms H, Virgin HW, Lenschow DJ, Stappenbeck TS.

Cell Host Microbe. 2015 Jan 14;17(1):85-97. doi: 10.1016/j.chom.2014.11.004. Epub 2014 Dec 4.


Elevated double negative T cells in pediatric autoimmunity.

Tarbox JA, Keppel MP, Topcagic N, Mackin C, Ben Abdallah M, Baszis KW, White AJ, French AR, Cooper MA.

J Clin Immunol. 2014 Jul;34(5):594-9. doi: 10.1007/s10875-014-0038-z. Epub 2014 Apr 24.


MicroRNA-155 tunes both the threshold and extent of NK cell activation via targeting of multiple signaling pathways.

Sullivan RP, Fogel LA, Leong JW, Schneider SE, Wong R, Romee R, Thai TH, Sexl V, Matkovich SJ, Dorn GW 2nd, French AR, Fehniger TA.

J Immunol. 2013 Dec 15;191(12):5904-13. doi: 10.4049/jimmunol.1301950. Epub 2013 Nov 13.


Murine cytomegalovirus protein pM92 is a conserved regulator of viral late gene expression.

Chapa TJ, Perng YC, French AR, Yu D.

J Virol. 2014 Jan;88(1):131-42. doi: 10.1128/JVI.02684-13. Epub 2013 Oct 16.


Hypogammaglobulinemia in pediatric systemic lupus erythematosus.

Lim E, Tao Y, White AJ, French AR, Cooper MA.

Lupus. 2013 Nov;22(13):1382-7. doi: 10.1177/0961203313507990. Epub 2013 Oct 8.


Mechanistic model of natural killer cell proliferative response to IL-15 receptor stimulation.

Zhao YM, French AR.

PLoS Comput Biol. 2013;9(9):e1003222. doi: 10.1371/journal.pcbi.1003222. Epub 2013 Sep 12.


Investigating models of protein function and allostery with a widespread mutational analysis of a light-activated protein.

Zayner JP, Antoniou C, French AR, Hause RJ Jr, Sosnick TR.

Biophys J. 2013 Aug 20;105(4):1027-36. doi: 10.1016/j.bpj.2013.07.010.


Natural killer cells in human autoimmune disorders.

Fogel LA, Yokoyama WM, French AR.

Arthritis Res Ther. 2013 Jul 11;15(4):216. doi: 10.1186/ar4232. Review.


Markers of nonselective and specific NK cell activation.

Fogel LA, Sun MM, Geurs TL, Carayannopoulos LN, French AR.

J Immunol. 2013 Jun 15;190(12):6269-76. doi: 10.4049/jimmunol.1202533. Epub 2013 May 8.


Reducing Muslim/Arab stereotypes through evaluative conditioning.

French AR, Franz TM, Phelan LL, Blaine BE.

J Soc Psychol. 2013 Jan-Feb;153(1):6-9.


Activation mechanisms of natural killer cells during influenza virus infection.

Hwang I, Scott JM, Kakarla T, Duriancik DM, Choi S, Cho C, Lee T, Park H, French AR, Beli E, Gardner E, Kim S.

PLoS One. 2012;7(12):e51858. doi: 10.1371/journal.pone.0051858. Epub 2012 Dec 31.


Natural killer cell functional defects in pediatric patients with severe and recurrent herpesvirus infections.

Ornstein BW, Hill EB, Geurs TL, French AR.

J Infect Dis. 2013 Feb 1;207(3):458-68. doi: 10.1093/infdis/jis701. Epub 2012 Nov 21.


Inositol tetrakisphosphate limits NK cell effector functions by controlling PI3K signaling.

Sauer K, Park E, Siegemund S, French AR, Wahle JA, Sternberg L, Rigaud S, Jonsson AH, Yokoyama WM, Huang YH.

Blood. 2013 Jan 10;121(2):286-97. doi: 10.1182/blood-2012-05-429241. Epub 2012 Nov 21.


The use of electroconvulsive therapy in a patient with juvenile systemic lupus erythematosus and catatonia.

Mon T, L'ecuyer S, Farber NB, White AJ, Baszis KW, Hearn JK, Spiegel TE, French AR, Kitcharoensakkul M.

Lupus. 2012 Dec;21(14):1575-81. doi: 10.1177/0961203312464803.


MicroRNA-deficient NK cells exhibit decreased survival but enhanced function.

Sullivan RP, Leong JW, Schneider SE, Keppel CR, Germino E, French AR, Fehniger TA.

J Immunol. 2012 Apr 1;188(7):3019-30. doi: 10.4049/jimmunol.1102294. Epub 2012 Feb 29.


Two-compartment model of NK cell proliferation: insights from population response to IL-15 stimulation.

Zhao YM, French AR.

J Immunol. 2012 Apr 1;188(7):2981-90. doi: 10.4049/jimmunol.1102989. Epub 2012 Feb 29.


Sex differences in murine susceptibility to systemic viral infections.

Geurs TL, Hill EB, Lippold DM, French AR.

J Autoimmun. 2012 May;38(2-3):J245-53. doi: 10.1016/j.jaut.2011.12.003. Epub 2011 Dec 29.


Fibrin matrices with affinity-based delivery systems and neurotrophic factors promote functional nerve regeneration.

Wood MD, MacEwan MR, French AR, Moore AM, Hunter DA, Mackinnon SE, Moran DW, Borschel GH, Sakiyama-Elbert SE.

Biotechnol Bioeng. 2010 Aug 15;106(6):970-9. doi: 10.1002/bit.22766.


Cutting edge: FcR-like 5 on innate B cells is targeted by a poxvirus MHC class I-like immunoevasin.

Campbell JA, Davis RS, Lilly LM, Fremont DH, French AR, Carayannopoulos LN.

J Immunol. 2010 Jul 1;185(1):28-32. doi: 10.4049/jimmunol.1000240. Epub 2010 Jun 2.


Ly49H engagement compensates for the absence of type I interferon signaling in stimulating NK cell proliferation during murine cytomegalovirus infection.

Geurs TL, Zhao YM, Hill EB, French AR.

J Immunol. 2009 Nov 1;183(9):5830-6. doi: 10.4049/jimmunol.0901520. Epub 2009 Oct 14.


Differential expression of granzyme B and C in murine cytotoxic lymphocytes.

Cai SF, Fehniger TA, Cao X, Mayer JC, Brune JD, French AR, Ley TJ.

J Immunol. 2009 May 15;182(10):6287-97. doi: 10.4049/jimmunol.0804333.


Ly49h is necessary for genetic resistance to murine cytomegalovirus.

Cheng TP, French AR, Plougastel BF, Pingel JT, Orihuela MM, Buller ML, Yokoyama WM.

Immunogenetics. 2008 Oct;60(10):565-73. doi: 10.1007/s00251-008-0313-3. Epub 2008 Jul 31.


HLA alleles determine differences in human natural killer cell responsiveness and potency.

Kim S, Sunwoo JB, Yang L, Choi T, Song YJ, French AR, Vlahiotis A, Piccirillo JF, Cella M, Colonna M, Mohanakumar T, Hsu KC, Dupont B, Yokoyama WM.

Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):3053-8. doi: 10.1073/pnas.0712229105. Epub 2008 Feb 19.


Rituximab for the treatment of juvenile dermatomyositis: a report of four pediatric patients.

Cooper MA, Willingham DL, Brown DE, French AR, Shih FF, White AJ.

Arthritis Rheum. 2007 Sep;56(9):3107-11.


Chronic lymphocytosis of functionally immature natural killer cells.

French AR, Kim S, Fehniger TA, Pratt JR, Yang L, Song YJ, Caligiuri MA, Yokoyama WM.

J Allergy Clin Immunol. 2007 Oct;120(4):924-31. Epub 2007 Jul 2.


Acquisition of murine NK cell cytotoxicity requires the translation of a pre-existing pool of granzyme B and perforin mRNAs.

Fehniger TA, Cai SF, Cao X, Bredemeyer AJ, Presti RM, French AR, Ley TJ.

Immunity. 2007 Jun;26(6):798-811. Epub 2007 May 31.


Histoplasmosis in a child with JRA on low-dose methotrexate.

Hunstad DA, French AR.

Rheumatology (Oxford). 2007 Jan;46(1):177-8. Epub 2006 Nov 18. Review. No abstract available.


IL-18 acts synergistically with IL-15 in stimulating natural killer cell proliferation.

French AR, Holroyd EB, Yang L, Kim S, Yokoyama WM.

Cytokine. 2006 Sep;35(5-6):229-34. Epub 2006 Oct 18.


DAP12 signaling directly augments proproliferative cytokine stimulation of NK cells during viral infections.

French AR, Sjölin H, Kim S, Koka R, Yang L, Young DA, Cerboni C, Tomasello E, Ma A, Vivier E, Kärre K, Yokoyama WM.

J Immunol. 2006 Oct 15;177(8):4981-90.


Arrested natural killer cell development associated with transgene insertion into the Atf2 locus.

Kim S, Song YJ, Higuchi DA, Kang HP, Pratt JR, Yang L, Hong CM, Poursine-Laurent J, Iizuka K, French AR, Sunwoo JB, Ishii S, Reimold AM, Yokoyama WM.

Blood. 2006 Feb 1;107(3):1024-30. Epub 2005 Oct 13.


Licensing of natural killer cells by host major histocompatibility complex class I molecules.

Kim S, Poursine-Laurent J, Truscott SM, Lybarger L, Song YJ, Yang L, French AR, Sunwoo JB, Lemieux S, Hansen TH, Yokoyama WM.

Nature. 2005 Aug 4;436(7051):709-13.


A lymphotoxin-IFN-beta axis essential for lymphocyte survival revealed during cytomegalovirus infection.

Banks TA, Rickert S, Benedict CA, Ma L, Ko M, Meier J, Ha W, Schneider K, Granger SW, Turovskaya O, Elewaut D, Otero D, French AR, Henry SC, Hamilton JD, Scheu S, Pfeffer K, Ware CF.

J Immunol. 2005 Jun 1;174(11):7217-25.


Rapid emergence of escape mutants following infection with murine cytomegalovirus in immunodeficient mice.

French AR, Pingel JT, Kim S, Yang L, Yokoyama WM.

Clin Immunol. 2005 Apr;115(1):61-9.


TLR9-dependent recognition of MCMV by IPC and DC generates coordinated cytokine responses that activate antiviral NK cell function.

Krug A, French AR, Barchet W, Fischer JA, Dzionek A, Pingel JT, Orihuela MM, Akira S, Yokoyama WM, Colonna M.

Immunity. 2004 Jul;21(1):107-19.


Escape of mutant double-stranded DNA virus from innate immune control.

French AR, Pingel JT, Wagner M, Bubic I, Yang L, Kim S, Koszinowski U, Jonjic S, Yokoyama WM.

Immunity. 2004 Jun;20(6):747-56.


The dynamic life of natural killer cells.

Yokoyama WM, Kim S, French AR.

Annu Rev Immunol. 2004;22:405-29. Review.


Natural killer cells and autoimmunity.

French AR, Yokoyama WM.

Arthritis Res Ther. 2004;6(1):8-14. Epub 2003 Dec 9.


Coordinate expression of cytokines and chemokines by NK cells during murine cytomegalovirus infection.

Dorner BG, Smith HR, French AR, Kim S, Poursine-Laurent J, Beckman DL, Pingel JT, Kroczek RA, Yokoyama WM.

J Immunol. 2004 Mar 1;172(5):3119-31.


Natural killer cells and viral infections.

French AR, Yokoyama WM.

Curr Opin Immunol. 2003 Feb;15(1):45-51. Review. No abstract available.


Osteopenia in adults with a history of juvenile rheumatoid arthritis. A population based study.

French AR, Mason T, Nelson AM, Crowson CS, O'Fallon WM, Khosla S, Gabriel SE.

J Rheumatol. 2002 May;29(5):1065-70.


In vivo developmental stages in murine natural killer cell maturation.

Kim S, Iizuka K, Kang HS, Dokun A, French AR, Greco S, Yokoyama WM.

Nat Immunol. 2002 Jun;3(6):523-8. Epub 2002 May 13.


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