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Items: 1 to 50 of 129

1.

Practice Change From Intermittent Medication Boluses to Bolusing From a Continuous Infusion in Pediatric Critical Care: A Quality Improvement Project.

Hochstetler JL, Thompson AJ, Ball NM, Evans MC, Frame SC, Haney AL, Little AK, O'Donnell JL, Rickett BM, Mack EH.

Pediatr Crit Care Med. 2018 Jun;19(6):572-577. doi: 10.1097/PCC.0000000000001549.

PMID:
29652752
2.

Impact of seasonality on the dynamics of native Vitamin D repletion in long-term renal transplant patients.

Ziff OJ, Penny H, Frame S, Cronin A, Goldsmith D.

Clin Kidney J. 2017 Jun;10(3):411-418. doi: 10.1093/ckj/sfw136. Epub 2017 Jan 7.

3.

Absorption, distribution, metabolism, excretion, and kinetics of 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid ammonium salt following a single dose in rat, mouse, and cynomolgus monkey.

Gannon SA, Fasano WJ, Mawn MP, Nabb DL, Buck RC, Buxton LW, Jepson GW, Frame SR.

Toxicology. 2016 Jan 18;340:1-9. doi: 10.1016/j.tox.2015.12.006. Epub 2015 Dec 29.

PMID:
26743852
4.

Evaluation of chronic toxicity and carcinogenicity of ammonium 2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)-propanoate in Sprague-Dawley rats.

Caverly Rae JM, Craig L, Slone TW, Frame SR, Buxton LW, Kennedy GL.

Toxicol Rep. 2015 Jun 30;2:939-949. doi: 10.1016/j.toxrep.2015.06.001. eCollection 2015.

5.

Comparative in vivo and in vitro analysis of possible estrogenic effects of perfluorooctanoic acid.

Yao PL, Ehresman DJ, Rae JM, Chang SC, Frame SR, Butenhoff JL, Kennedy GL, Peters JM.

Toxicology. 2014 Dec 4;326:62-73. doi: 10.1016/j.tox.2014.10.008. Epub 2014 Oct 18.

PMID:
25456267
6.

Data sharing reveals complexity in the westward spread of domestic animals across Neolithic Turkey.

Arbuckle BS, Kansa SW, Kansa E, Orton D, Çakırlar C, Gourichon L, Atici L, Galik A, Marciniak A, Mulville J, Buitenhuis H, Carruthers D, De Cupere B, Demirergi A, Frame S, Helmer D, Martin L, Peters J, Pöllath N, Pawłowska K, Russell N, Twiss K, Würtenberger D.

PLoS One. 2014 Jun 13;9(6):e99845. doi: 10.1371/journal.pone.0099845. eCollection 2014. Erratum in: PLoS One. 2014;9(9):e107824.

7.

Pathology review of proliferative lesions of the exocrine pancreas in two chronic feeding studies in rats with ammonium perfluorooctanoate.

Caverly Rae JM, Frame SR, Kennedy GL, Butenhoff JL, Chang SC.

Toxicol Rep. 2014 May 2;1:85-91. doi: 10.1016/j.toxrep.2014.04.005. eCollection 2014.

8.

Toxicological evaluation of 6:2 fluorotelomer alcohol.

Serex T, Anand S, Munley S, Donner EM, Frame SR, Buck RC, Loveless SE.

Toxicology. 2014 May 7;319:1-9. doi: 10.1016/j.tox.2014.01.009. Epub 2014 Feb 24.

PMID:
24576572
9.

Occurrence of spontaneous amphophilic-vacuolar renal tubule tumors in Sprague-Dawley rats from subchronic toxicity studies.

Crabbs TA, Frame SR, Laast VA, Patrick DJ, Thomas J, Zimmerman B, Hardisty JF.

Toxicol Pathol. 2013 Aug;41(6):866-71. doi: 10.1177/0192623312467523. Epub 2012 Dec 21.

PMID:
23262636
10.

Thirteen week rodent feeding study with grain from molecular stacked trait lepidopteran and coleopteran protected (DP-ØØ4114-3) maize.

Delaney B, Karaman S, Roper J, Hoban D, Sykes G, Mukerji P, Frame SR.

Food Chem Toxicol. 2013 Mar;53:417-27.

11.

A species difference in the peroxisome proliferator-activated receptor α-dependent response to the developmental effects of perfluorooctanoic acid.

Albrecht PP, Torsell NE, Krishnan P, Ehresman DJ, Frame SR, Chang SC, Butenhoff JL, Kennedy GL, Gonzalez FJ, Peters JM.

Toxicol Sci. 2013 Feb;131(2):568-82. doi: 10.1093/toxsci/kfs318. Epub 2012 Nov 9.

PMID:
23143925
12.

Determinants of vitamin D status in long-term renal transplant patients.

Penny H, Frame S, Dickinson F, Garrett G, Young AR, Sarkany R, Chitalia N, Hampson G, Goldsmith D.

Clin Transplant. 2012 Nov-Dec;26(6):E617-23. doi: 10.1111/ctr.12039. Epub 2012 Oct 22.

PMID:
23083399
13.

Ninety-day inhalation toxicity study with a vapor grown carbon nanofiber in rats.

Delorme MP, Muro Y, Arai T, Banas DA, Frame SR, Reed KL, Warheit DB.

Toxicol Sci. 2012 Aug;128(2):449-60. doi: 10.1093/toxsci/kfs172. Epub 2012 May 10.

PMID:
22581831
14.

Safety assessment of EPA-rich triglyceride oil produced from yeast: genotoxicity and 28-day oral toxicity in rats.

Belcher LA, MacKenzie SA, Donner M, Sykes GP, Frame SR, Gillies PJ.

Regul Toxicol Pharmacol. 2011 Feb;59(1):53-63. doi: 10.1016/j.yrtph.2010.09.007. Epub 2010 Sep 22.

PMID:
20868718
15.

Phase I evaluation of seliciclib (R-roscovitine), a novel oral cyclin-dependent kinase inhibitor, in patients with advanced malignancies.

Le Tourneau C, Faivre S, Laurence V, Delbaldo C, Vera K, Girre V, Chiao J, Armour S, Frame S, Green SR, Gianella-Borradori A, Diéras V, Raymond E.

Eur J Cancer. 2010 Dec;46(18):3243-50. doi: 10.1016/j.ejca.2010.08.001. Epub 2010 Sep 6.

PMID:
20822897
16.

Safety assessment of EPA-rich oil produced from yeast: Results of a 90-day subchronic toxicity study.

MacKenzie SA, Belcher LA, Sykes GP, Frame SR, Mukerji P, Gillies PJ.

Regul Toxicol Pharmacol. 2010 Dec;58(3):490-500. doi: 10.1016/j.yrtph.2010.08.021. Epub 2010 Sep 8.

PMID:
20804805
17.

Pathology Working Group review and evaluation of proliferative lesions of mammary gland tissues in female rats fed ammonium perfluorooctanoate (APFO) in the diet for 2 years.

Hardisty JF, Willson GA, Brown WR, McConnell EE, Frame SR, Gaylor DW, Kennedy GL, Butenhoff JL.

Drug Chem Toxicol. 2010 Apr;33(2):131-7. doi: 10.3109/01480541003667610.

PMID:
20307141
18.

Pulmonary exposures to Sepiolite nanoclay particulates in rats: resolution following multinucleate giant cell formation.

Warheit DB, Sayes CM, Frame SR, Reed KL.

Toxicol Lett. 2010 Feb 15;192(3):286-93. doi: 10.1016/j.toxlet.2009.11.006. Epub 2009 Nov 10.

PMID:
19900512
19.

Toxicological evaluation of sodium perfluorohexanoate.

Loveless SE, Slezak B, Serex T, Lewis J, Mukerji P, O'Connor JC, Donner EM, Frame SR, Korzeniowski SH, Buck RC.

Toxicology. 2009 Oct 1;264(1-2):32-44. doi: 10.1016/j.tox.2009.07.011. Epub 2009 Jul 24.

PMID:
19632293
20.

Therapeutic efficacy of seliciclib in combination with ionizing radiation for human nasopharyngeal carcinoma.

Hui AB, Yue S, Shi W, Alajez NM, Ito E, Green SR, Frame S, O'Sullivan B, Liu FF.

Clin Cancer Res. 2009 Jun 1;15(11):3716-24. doi: 10.1158/1078-0432.CCR-08-2790. Epub 2009 May 26.

21.

Immunotoxicity of perfluorooctanoic acid and perfluorooctane sulfonate and the role of peroxisome proliferator-activated receptor alpha.

DeWitt JC, Shnyra A, Badr MZ, Loveless SE, Hoban D, Frame SR, Cunard R, Anderson SE, Meade BJ, Peden-Adams MM, Luebke RW, Luster MI.

Crit Rev Toxicol. 2009;39(1):76-94. doi: 10.1080/10408440802209804 . Review.

PMID:
18802816
22.

Subchronic, reproductive, and developmental toxicity of a fluorotelomer-based urethane polymeric product.

Stadler JC, Delker DA, Malley LA, Frame SR, Everds NE, Mylchreest E, Munley SM, Loveless SE, Buck RC.

Drug Chem Toxicol. 2008;31(3):317-37. doi: 10.1080/01480540701873418 .

PMID:
18622868
23.

Synergistic inhibition of ErbB signaling by combined treatment with seliciclib and ErbB-targeting agents.

Fleming IN, Hogben M, Frame S, McClue SJ, Green SR.

Clin Cancer Res. 2008 Jul 1;14(13):4326-35. doi: 10.1158/1078-0432.CCR-07-4633.

24.

Evaluation of the immune system in rats and mice administered linear ammonium perfluorooctanoate.

Loveless SE, Hoban D, Sykes G, Frame SR, Everds NE.

Toxicol Sci. 2008 Sep;105(1):86-96. doi: 10.1093/toxsci/kfn113. Epub 2008 Jun 16.

PMID:
18559402
25.

90-day oral gavage toxicity study of 8-2 fluorotelomer alcohol in rats.

Ladics GS, Kennedy GL, O'Connor J, Everds N, Malley LA, Frame SR, Gannon S, Jung R, Roth T, Iwai H, Shin-Ya S.

Drug Chem Toxicol. 2008;31(2):189-216. doi: 10.1080/01480540701873103 .

PMID:
18330782
26.

Hospital admissions and deaths relating to deliberate self-harm and accidents within 5 years of a cancer diagnosis: a national study in Scotland, UK.

Camidge DR, Stockton DL, Frame S, Wood R, Bain M, Bateman DN.

Br J Cancer. 2007 Mar 12;96(5):752-7. Epub 2007 Feb 13.

27.

Characterization and reclassification of titanium dioxide-related pulmonary lesions.

Warheit DB, Frame SR.

J Occup Environ Med. 2006 Dec;48(12):1308-13.

PMID:
17159646
28.

FRAT1, a substrate-specific regulator of glycogen synthase kinase-3 activity, is a cellular substrate of protein kinase A.

Hagen T, Cross DA, Culbert AA, West A, Frame S, Morrice N, Reith AD.

J Biol Chem. 2006 Nov 17;281(46):35021-9. Epub 2006 Sep 18.

29.

Short-term and long-term outcomes in 133,429 emergency patients admitted with angina or myocardial infarction in Scotland, 1990-2000: population-based cohort study.

Capewell S, Murphy NF, MacIntyre K, Frame S, Stewart S, Chalmers JW, Boyd J, Finlayson A, Redpath A, McMurray JJ.

Heart. 2006 Nov;92(11):1563-70. Epub 2006 Jun 14.

31.

Targeting glycogen synthase kinase-3 in insulin signalling.

Frame S, Zheleva D.

Expert Opin Ther Targets. 2006 Jun;10(3):429-44. Review.

PMID:
16706683
32.

Hospital burden of suspected acute coronary syndromes: recent trends.

MacIntyre K, Murphy NF, Chalmers J, Capewell S, Frame S, Finlayson A, Pell J, Redpath A, McMurray JJ.

Heart. 2006 May;92(5):691-2. No abstract available.

33.

Comparative responses of rats and mice exposed to linear/branched, linear, or branched ammonium perfluorooctanoate (APFO).

Loveless SE, Finlay C, Everds NE, Frame SR, Gillies PJ, O'Connor JC, Powley CR, Kennedy GL.

Toxicology. 2006 Mar 15;220(2-3):203-17. Epub 2006 Jan 31.

PMID:
16448737
34.

Acute, subchronic, and mutagenicity studies with norbornene fluoroalcohol.

DeLorme MP, Ladics GS, Donner EM, Wagner VO 3rd, Finlay C, Frame SR, Everds NE, Loveless SE.

Drug Chem Toxicol. 2005;28(4):379-95.

PMID:
16298870
35.

Molecular characterization of thyroid toxicity: anchoring gene expression profiles to biochemical and pathologic end points.

Glatt CM, Ouyang M, Welsh W, Green JW, Connor JO, Frame SR, Everds NE, Poindexter G, Snajdr S, Delker DA.

Environ Health Perspect. 2005 Oct;113(10):1354-61.

36.
37.

Inhalation toxicity of 1,3-propanediol in the rat.

Scott RS, Frame SR, Ross PE, Loveless SE, Kennedy GL.

Inhal Toxicol. 2005 Aug;17(9):487-93.

PMID:
16020043
38.

Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1.

MacCallum DE, Melville J, Frame S, Watt K, Anderson S, Gianella-Borradori A, Lane DP, Green SR.

Cancer Res. 2005 Jun 15;65(12):5399-407.

39.

Using others' words: conversational use of reported speech by individuals with aphasia and their communication partners.

Hengst JA, Frame SR, Neuman-Stritzel T, Gannaway R.

J Speech Lang Hear Res. 2005 Feb;48(1):137-56.

PMID:
15934449
40.

STP position paper: best practice guideline for the routine pathology evaluation of the immune system.

Haley P, Perry R, Ennulat D, Frame S, Johnson C, Lapointe JM, Nyska A, Snyder P, Walker D, Walter G; STP Immunotoxicology Working Group.

Toxicol Pathol. 2005;33(3):404-7; discussion 408. No abstract available.

PMID:
15805080
41.

Inhalation toxicology of fumed dodecanediamine.

Valentine R, Frame S, Kennedy G.

Inhal Toxicol. 2004 Sep;16(10):721-9.

PMID:
15371059
42.

Benefits of specialisation in the management of pancreatic cancer: results of a Scottish population-based study.

Parks RW, Bettschart V, Frame S, Stockton DL, Brewster DH, Garden OJ.

Br J Cancer. 2004 Aug 2;91(3):459-65.

43.

Hospital discharge rates for suspected acute coronary syndromes between 1990 and 2000: population based analysis.

Murphy NF, MacIntyre K, Capewell S, Stewart S, Pell J, Chalmers J, Redpath A, Frame S, Boyd J, McMurray JJ.

BMJ. 2004 Jun 12;328(7453):1413-4. Epub 2004 May 21. No abstract available.

44.

The reproductive toxicology of ammonium perfluorooctanoate (APFO) in the rat.

Butenhoff JL, Kennedy GL Jr, Frame SR, O'Connor JC, York RG.

Toxicology. 2004 Mar 1;196(1-2):95-116.

PMID:
15036760
46.

Inhalation toxicity of methylglutaronitrile in rats.

Kelly DP, Frame SR, Malley LA, Everds NE, Kennedy GL Jr.

Drug Chem Toxicol. 2003 May;26(2):99-115.

PMID:
12816395
47.

Pelvic fracture in the elderly is associated with increased mortality.

O'brien DP, Luchette FA, Pereira SJ, Lim E, Seeskin CS, James L, Miller S, Davis K Jr, Hurst JM, Johannigman JA, Frame SB.

Surgery. 2002 Oct;132(4):710-4; discussion 714-5.

PMID:
12407356
48.

Phosphorylation of the regulatory subunit of smooth muscle protein phosphatase 1M at Thr850 induces its dissociation from myosin.

Velasco G, Armstrong C, Morrice N, Frame S, Cohen P.

FEBS Lett. 2002 Sep 11;527(1-3):101-4.

49.

Evaluation of a 15-day screening assay using intact male rats for identifying antiandrogens.

O'Connor JC, Frame SR, Ladics GS.

Toxicol Sci. 2002 Sep;69(1):92-108.

PMID:
12215663
50.

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