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Cardiovascular responses to progressive hypoxia in ducks native to high altitude in the Andes.

Lague SL, Ivy CM, York JM, Chua BA, Alza L, Cheek R, Dawson NJ, Frappell PB, Farrell AP, McCracken KG, Scott GR, Milsom WK.

J Exp Biol. 2020 Feb 10. pii: jeb.211250. doi: 10.1242/jeb.211250. [Epub ahead of print]


Effects of diluted bitumen exposure and recovery on the seawater acclimation response of Atlantic salmon smolts.

Alderman SL, Dilkumar CM, Avey SR, Farrell AP, Kennedy CJ, Gillis TE.

Aquat Toxicol. 2020 Jan 20;221:105419. doi: 10.1016/j.aquatox.2020.105419. [Epub ahead of print]


Effects of diluted bitumen exposure on Atlantic salmon smolts: Molecular and metabolic responses in relation to swimming performance.

Avey SR, Kennedy CJ, Farrell AP, Gillis TE, Alderman SL.

Aquat Toxicol. 2020 Jan 23;221:105423. doi: 10.1016/j.aquatox.2020.105423. [Epub ahead of print]


Corrigendum: High-Load Reovirus Infections Do Not Imply Physiological Impairment in Salmon.

Zhang Y, Polinski MP, Morrison PR, Brauner CJ, Farrell AP, Garver KA.

Front Physiol. 2019 Oct 29;10:1354. doi: 10.3389/fphys.2019.01354. eCollection 2019.


Discovery and validation of candidate smoltification gene expression biomarkers across multiple species and ecotypes of Pacific salmonids.

Houde ALS, Günther OP, Strohm J, Ming TJ, Li S, Kaukinen KH, Patterson DA, Farrell AP, Hinch SG, Miller KM.

Conserv Physiol. 2019 Oct 11;7(1):coz051. doi: 10.1093/conphys/coz051. eCollection 2019.


Maximum cardiac performance of Antarctic fishes that lack haemoglobin and myoglobin: exploring the effect of warming on nature's natural knockouts.

Egginton S, Axelsson M, Crockett EL, O'Brien KM, Farrell AP.

Conserv Physiol. 2019 Oct 11;7(1):coz049. doi: 10.1093/conphys/coz049. eCollection 2019.


The effect of acute warming and thermal acclimation on maximum heart rate of the common killifish Fundulus heteroclitus.

Safi H, Zhang Y, Schulte PM, Farrell AP.

J Fish Biol. 2019 Dec;95(6):1441-1446. doi: 10.1111/jfb.14159. Epub 2019 Nov 11.


Membrane and calcium clock mechanisms contribute variably as a function of temperature to setting cardiac pacemaker rate in zebrafish Danio rerio.

Marchant JL, Farrell AP.

J Fish Biol. 2019 Nov;95(5):1265-1274. doi: 10.1111/jfb.14126. Epub 2019 Oct 21.


Within-host infectious disease models accommodating cellular coinfection, with an application to influenza.

Koelle K, Farrell AP, Brooke CB, Ke R.

Virus Evol. 2019 Jul 8;5(2):vez018. doi: 10.1093/ve/vez018. eCollection 2019 Jul. Erratum in: Virus Evol. 2019 Nov 19;5(2):vez052.


Salmonid gene expression biomarkers indicative of physiological responses to changes in salinity and temperature, but not dissolved oxygen.

Houde ALS, Akbarzadeh A, Günther OP, Li S, Patterson DA, Farrell AP, Hinch SG, Miller KM.

J Exp Biol. 2019 Jul 5;222(Pt 13). pii: jeb198036. doi: 10.1242/jeb.198036.


Finding the peak of dynamic oxygen uptake during fatiguing exercise in fish.

Zhang Y, Gilbert MJH, Farrell AP.

J Exp Biol. 2019 Jun 25;222(Pt 12). pii: jeb196568. doi: 10.1242/jeb.196568.


Autonomic cardiac regulation facilitates acute heat tolerance in rainbow trout: in situ and in vivo support.

Gilbert MJH, Rani V, McKenzie SM, Farrell AP.

J Exp Biol. 2019 May 2;222(Pt 9). pii: jeb194365. doi: 10.1242/jeb.194365.


Scaling of cardiac morphology is interrupted by birth in the developing sheep Ovis aries.

Snelling EP, Seymour RS, Giussani DA, Fuller A, Maloney SK, Farrell AP, Mitchell D, George KP, Dzialowski EM, Jonker SS, Wube T.

J Anat. 2019 Jul;235(1):96-105. doi: 10.1111/joa.12990. Epub 2019 Apr 17.


High-Load Reovirus Infections Do Not Imply Physiological Impairment in Salmon.

Zhang Y, Polinski MP, Morrison PR, Brauner CJ, Farrell AP, Garver KA.

Front Physiol. 2019 Mar 13;10:114. doi: 10.3389/fphys.2019.00114. eCollection 2019. Erratum in: Front Physiol. 2019 Oct 29;10:1354.


Don't throw the fish out with the respirometry water.

Regan MD, Mandic M, Dhillon RS, Lau GY, Farrell AP, Schulte PM, Seibel BA, Speers-Roesch B, Ultsch GR, Richards JG.

J Exp Biol. 2019 Mar 28;222(Pt 6). pii: jeb200253. doi: 10.1242/jeb.200253. No abstract available.


Adrenergic and adenosinergic regulation of the cardiovascular system in an Antarctic icefish: Insight into central and peripheral determinants of cardiac output.

Joyce W, Egginton S, Farrell AP, Axelsson M.

Comp Biochem Physiol A Mol Integr Physiol. 2019 Apr;230:28-38. doi: 10.1016/j.cbpa.2018.12.012. Epub 2018 Dec 28.


The effects of thermal acclimation on cardio-respiratory performance in an Antarctic fish (Notothenia coriiceps).

Joyce W, Axelsson M, Egginton S, Farrell AP, Crockett EL, O'Brien KM.

Conserv Physiol. 2018 Dec 13;6(1):coy069. doi: 10.1093/conphys/coy069. eCollection 2018.


Transcriptional shifts during juvenile Coho salmon (Oncorhynchus kisutch) life stage changes in freshwater and early marine environments.

Houde ALS, Schulze AD, Kaukinen KH, Strohm J, Patterson DA, Beacham TD, Farrell AP, Hinch SG, Miller KM.

Comp Biochem Physiol Part D Genomics Proteomics. 2019 Mar;29:32-42. doi: 10.1016/j.cbd.2018.10.002. Epub 2018 Oct 18.


Predicted impacts of climate warming on aerobic performance and upper thermal tolerance of six tropical freshwater fishes spanning three continents.

Lapointe D, Cooperman MS, Chapman LJ, Clark TD, Val AL, Ferreira MS, Balirwa JS, Mbabazi D, Mwanja M, Chhom L, Hannah L, Kaufman L, Farrell AP, Cooke SJ.

Conserv Physiol. 2018 Oct 15;6(1):coy056. doi: 10.1093/conphys/coy056. eCollection 2018.


Physiological and genomic signatures of evolutionary thermal adaptation in redband trout from extreme climates.

Chen Z, Farrell AP, Matala A, Hoffman N, Narum SR.

Evol Appl. 2018 Jul 20;11(9):1686-1699. doi: 10.1111/eva.12672. eCollection 2018 Oct.


A solution to Nature's haemoglobin knockout: a plasma-accessible carbonic anhydrase catalyses CO2 excretion in Antarctic icefish gills.

Harter TS, Sackville MA, Wilson JM, Metzger DCH, Egginton S, Esbaugh AJ, Farrell AP, Brauner CJ.

J Exp Biol. 2018 Nov 19;221(Pt 22). pii: jeb190918. doi: 10.1242/jeb.190918.


Ameliorating the adverse cardiorespiratory effects of chemical immobilization by inducing general anaesthesia in sheep and goats: implications for physiological studies of large wild mammals.

Izwan A, Snelling EP, Seymour RS, Meyer LCR, Fuller A, Haw A, Mitchell D, Farrell AP, Costello MA, Maloney SK.

J Comp Physiol B. 2018 Nov;188(6):991-1003. doi: 10.1007/s00360-018-1184-z. Epub 2018 Sep 19.


Assessing the long-term effect of exposure to dispersant-treated oil on fish health using hypoxia tolerance and temperature susceptibility as ecologically relevant biomarkers.

Mauduit F, Farrell AP, Domenici P, Lacroix C, Le Floch S, Lemaire P, Nicolas-Kopec A, Whittington M, Le Bayon N, Zambonino-Infante JL, Claireaux G.

Environ Toxicol Chem. 2019 Jan;38(1):210-221. doi: 10.1002/etc.4271. Epub 2018 Nov 30.


Editorial July 2018.

Farrell AP.

J Fish Biol. 2018 Jul;93(1):3-4. doi: 10.1111/jfb.13753. No abstract available.


Scaling of morphology and ultrastructure of hearts among wild African antelope.

Snelling EP, Maloney SK, Farrell AP, Meyer LCR, Izwan A, Fuller A, Mitchell D, Haw A, Costello MA, Seymour RS.

J Exp Biol. 2018 Sep 5;221(Pt 17). pii: jeb184713. doi: 10.1242/jeb.184713.


Exploring nature's natural knockouts: in vivo cardiorespiratory performance of Antarctic fishes during acute warming.

Joyce W, Egginton S, Farrell AP, Crockett EL, O'Brien KM, Axelsson M.

J Exp Biol. 2018 Aug 13;221(Pt 15). pii: jeb183160. doi: 10.1242/jeb.183160.


Developmental and latent effects of diluted bitumen exposure on early life stages of sockeye salmon (Oncorhynchus nerka).

Alderman SL, Lin F, Gillis TE, Farrell AP, Kennedy CJ.

Aquat Toxicol. 2018 Sep;202:6-15. doi: 10.1016/j.aquatox.2018.06.014. Epub 2018 Jun 26.


Cardiac mitochondrial metabolism may contribute to differences in thermal tolerance of red- and white-blooded Antarctic notothenioid fishes.

O'Brien KM, Rix AS, Egginton S, Farrell AP, Crockett EL, Schlauch K, Woolsey R, Hoffman M, Merriman S.

J Exp Biol. 2018 Aug 13;221(Pt 15). pii: jeb177816. doi: 10.1242/jeb.177816.


Vacuum Furnace for Degassing Stainless-Steel Vacuum Components.

Fedchak JA, Scherschligt J, Barker D, Eckel S, Farrell AP, Sefa M.

J Vac Sci Technol A. 2018 Mar;36(2). pii: 023201. doi: 10.1116/1.5016181.


Do fatal infectious diseases eradicate host species?

Farrell AP, Collins JP, Greer AL, Thieme HR.

J Math Biol. 2018 Dec;77(6-7):2103-2164. doi: 10.1007/s00285-018-1249-3. Epub 2018 May 21.


Times from Infection to Disease-Induced Death and their Influence on Final Population Sizes After Epidemic Outbreaks.

Farrell AP, Collins JP, Greer AL, Thieme HR.

Bull Math Biol. 2018 Jul;80(7):1937-1961. doi: 10.1007/s11538-018-0446-y. Epub 2018 May 21.


A three-phase excess post-exercise oxygen consumption in Atlantic salmon Salmo salar and its response to exercise training.

Zhang Y, Claireaux G, Takle H, Jørgensen SM, Farrell AP.

J Fish Biol. 2018 May;92(5):1385-1403. doi: 10.1111/jfb.13593. Epub 2018 Mar 9.


A rainbow trout Oncorhynchus mykiss strain with higher aerobic scope in normoxia also has superior tolerance of hypoxia.

Zhang Y, Healy TM, Vandersteen W, Schulte PM, Farrell AP.

J Fish Biol. 2018 Feb;92(2):487-503. doi: 10.1111/jfb.13530.


Mechanisms of thermal adaptation and evolutionary potential of conspecific populations to changing environments.

Chen Z, Farrell AP, Matala A, Narum SR.

Mol Ecol. 2018 Feb;27(3):659-674. doi: 10.1111/mec.14475. Epub 2018 Jan 31.


Hematocrit Is Associated with Thermal Tolerance and Modulated by Developmental Temperature in Juvenile Chinook Salmon.

Muñoz NJ, Farrell AP, Heath JW, Neff BD.

Physiol Biochem Zool. 2018 Jan/Feb;91(1):757-762. doi: 10.1086/695556.


Divergent respiratory and cardiovascular responses to hypoxia in bar-headed geese and Andean birds.

Lague SL, Chua B, Alza L, Scott GR, Frappell PB, Zhong Y, Farrell AP, McCracken KG, Wang Y, Milsom WK.

J Exp Biol. 2017 Nov 15;220(Pt 22):4186-4194. doi: 10.1242/jeb.168799.


Avoidance threshold to oil water-soluble fraction by a juvenile marine teleost fish.

Claireaux G, Quéau P, Marras S, Le Floch S, Farrell AP, Nicolas-Kopec A, Lemaire P, Domenici P.

Environ Toxicol Chem. 2018 Mar;37(3):854-859. doi: 10.1002/etc.4019. Epub 2017 Dec 30.


Ecology of Exercise in Wild Fish: Integrating Concepts of Individual Physiological Capacity, Behavior, and Fitness Through Diverse Case Studies.

Brownscombe JW, Cooke SJ, Algera DA, Hanson KC, Eliason EJ, Burnett NJ, Danylchuk AJ, Hinch SG, Farrell AP.

Integr Comp Biol. 2017 Aug 1;57(2):281-292. doi: 10.1093/icb/icx012.


Capture severity, infectious disease processes and sex influence post-release mortality of sockeye salmon bycatch.

Teffer AK, Hinch SG, Miller KM, Patterson DA, Farrell AP, Cooke SJ, Bass AL, Szekeres P, Juanes F.

Conserv Physiol. 2017 Mar 28;5(1):cox017. doi: 10.1093/conphys/cox017. eCollection 2017.


Exposure of European sea bass (Dicentrarchus labrax) to chemically dispersed oil has a chronic residual effect on hypoxia tolerance but not aerobic scope.

Zhang Y, Mauduit F, Farrell AP, Chabot D, Ollivier H, Rio-Cabello A, Le Floch S, Claireaux G.

Aquat Toxicol. 2017 Oct;191:95-104. doi: 10.1016/j.aquatox.2017.07.020. Epub 2017 Aug 1.


Proteomic analysis of sockeye salmon serum as a tool for biomarker discovery and new insight into the sublethal toxicity of diluted bitumen.

Alderman SL, Dindia LA, Kennedy CJ, Farrell AP, Gillis TE.

Comp Biochem Physiol Part D Genomics Proteomics. 2017 Jun;22:157-166. doi: 10.1016/j.cbd.2017.04.003. Epub 2017 Apr 12.


Na+/K+-ATPase activity in the anoxic turtle (Trachemys scripta) brain at different acclimation temperature.

Stecyk JA, Farrell AP, Vornanen M.

Comp Biochem Physiol A Mol Integr Physiol. 2017 Apr;206:11-16. doi: 10.1016/j.cbpa.2017.01.002. Epub 2017 Jan 13.


Unusual aerobic performance at high temperatures in juvenile Chinook salmon, Oncorhynchus tshawytscha.

Poletto JB, Cocherell DE, Baird SE, Nguyen TX, Cabrera-Stagno V, Farrell AP, Fangue NA.

Conserv Physiol. 2017 Jan 4;5(1):cow067. doi: 10.1093/conphys/cow067. eCollection 2017.


High thermal tolerance of a rainbow trout population near its southern range limit suggests local thermal adjustment.

Verhille CE, English KK, Cocherell DE, Farrell AP, Fangue NA.

Conserv Physiol. 2016 Dec 9;4(1):cow057. eCollection 2016.


A perspective on physiological studies supporting the provision of scientific advice for the management of Fraser River sockeye salmon (Oncorhynchus nerka).

Patterson DA, Cooke SJ, Hinch SG, Robinson KA, Young N, Farrell AP, Miller KM.

Conserv Physiol. 2016 Aug 26;4(1):cow026. eCollection 2016. Review.


Introducing a novel mechanism to control heart rate in the ancestral Pacific hagfish.

Wilson CM, Roa JN, Cox GK, Tresguerres M, Farrell AP.

J Exp Biol. 2016 Oct 15;219(Pt 20):3227-3236. Epub 2016 Aug 10.


Determinants of coronary blood flow in sandbar sharks, Carcharhinus plumbeus.

Cox GK, Brill RW, Bonaro KA, Farrell AP.

J Comp Physiol B. 2017 Feb;187(2):315-327. doi: 10.1007/s00360-016-1033-x. Epub 2016 Sep 27.


A structure-function analysis of the left ventricle.

Snelling EP, Seymour RS, Green JE, Meyer LC, Fuller A, Haw A, Mitchell D, Farrell AP, Costello MA, Izwan A, Badenhorst M, Maloney SK.

J Appl Physiol (1985). 2016 Oct 1;121(4):900-909. doi: 10.1152/japplphysiol.00435.2016. Epub 2016 Sep 1.


Assessing chronic fish health: An application to a case of an acute exposure to chemically treated crude oil.

Mauduit F, Domenici P, Farrell AP, Lacroix C, Le Floch S, Lemaire P, Nicolas-Kopec A, Whittington M, Zambonino-Infante JL, Claireaux G.

Aquat Toxicol. 2016 Sep;178:197-208. doi: 10.1016/j.aquatox.2016.07.019. Epub 2016 Aug 2.


Tracking wild sockeye salmon smolts to the ocean reveals distinct regions of nocturnal movement and high mortality.

Clark TD, Furey NB, Rechisky EL, Gale MK, Jeffries KM, Porter AD, Casselman MT, Lotto AG, Patterson DA, Cooke SJ, Farrell AP, Welch DW, Hinch SG.

Ecol Appl. 2016 Jun;26(4):959-78.


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