Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 144

1.

Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators.

Clapper JR, Henry CL, Niphakis MJ, Knize AM, Coppola AR, Simon GM, Ngo N, Herbst RA, Herbst DM, Reed AW, Cisar JS, Weber OD, Viader A, Alexander JP, Cunningham ML, Jones TK, Fraser IP, Grice CA, Ezekowitz RAB, O'Neill GP, Blankman JL.

J Pharmacol Exp Ther. 2018 Oct 10. pii: jpet.118.252296. doi: 10.1124/jpet.118.252296. [Epub ahead of print]

2.

Identification of ABX-1431, a Selective Inhibitor of Monoacylglycerol Lipase and Clinical Candidate for Treatment of Neurological Disorders.

Cisar JS, Weber OD, Clapper JR, Blankman JL, Henry CL, Simon GM, Alexander JP, Jones TK, Ezekowitz RAB, O'Neill GP, Grice CA.

J Med Chem. 2018 Oct 25;61(20):9062-9084. doi: 10.1021/acs.jmedchem.8b00951. Epub 2018 Aug 23.

PMID:
30067909
3.

Monoacylglycerol lipase inhibitor JZL184 improves behavior and neural properties in Ts65Dn mice, a model of down syndrome.

Lysenko LV, Kim J, Henry C, Tyrtyshnaia A, Kohnz RA, Madamba F, Simon GM, Kleschevnikova NE, Nomura DK, Ezekowitz RA, Kleschevnikov AM.

PLoS One. 2014 Dec 4;9(12):e114521. doi: 10.1371/journal.pone.0114521. eCollection 2014.

4.

Mannose-binding lectin regulates host resistance and pathology during experimental infection with Trypanosoma cruzi.

Rothfuchs AG, Roffê E, Gibson A, Cheever AW, Ezekowitz RA, Takahashi K, Steindel M, Sher A, Báfica A.

PLoS One. 2012;7(11):e47835. doi: 10.1371/journal.pone.0047835. Epub 2012 Nov 6.

5.

High-dose mannose-binding lectin therapy for Ebola virus infection.

Michelow IC, Lear C, Scully C, Prugar LI, Longley CB, Yantosca LM, Ji X, Karpel M, Brudner M, Takahashi K, Spear GT, Ezekowitz RA, Schmidt EV, Olinger GG.

J Infect Dis. 2011 Jan 15;203(2):175-9. doi: 10.1093/infdis/jiq025.

6.

A novel L-ficolin/mannose-binding lectin chimeric molecule with enhanced activity against Ebola virus.

Michelow IC, Dong M, Mungall BA, Yantosca LM, Lear C, Ji X, Karpel M, Rootes CL, Brudner M, Houen G, Eisen DP, Kinane TB, Takahashi K, Stahl GL, Olinger GG, Spear GT, Ezekowitz RA, Schmidt EV.

J Biol Chem. 2010 Aug 6;285(32):24729-39. doi: 10.1074/jbc.M110.106260. Epub 2010 Jun 1.

7.

Mannose-binding lectin and innate immunity.

Ip WK, Takahashi K, Ezekowitz RA, Stuart LM.

Immunol Rev. 2009 Jul;230(1):9-21. doi: 10.1111/j.1600-065X.2009.00789.x. Review.

PMID:
19594626
8.

Deficiency of mannose-binding lectin greatly increases antibody response in a mouse model of vaccination.

Guttormsen HK, Stuart LM, Shi L, Carroll MC, Chen J, Kasper DL, Ezekowitz RA, Takahashi K.

Clin Immunol. 2009 Mar;130(3):264-71. doi: 10.1016/j.clim.2008.09.012. Epub 2008 Nov 8.

9.

Phagocytosis and comparative innate immunity: learning on the fly.

Stuart LM, Ezekowitz RA.

Nat Rev Immunol. 2008 Feb;8(2):131-41. doi: 10.1038/nri2240. Review.

PMID:
18219310
10.

Mannose-binding lectin enhances Toll-like receptors 2 and 6 signaling from the phagosome.

Ip WK, Takahashi K, Moore KJ, Stuart LM, Ezekowitz RA.

J Exp Med. 2008 Jan 21;205(1):169-81. doi: 10.1084/jem.20071164. Epub 2008 Jan 7.

11.

Reduced tissue damage and improved recovery of motor function after traumatic brain injury in mice deficient in complement component C4.

You Z, Yang J, Takahashi K, Yager PH, Kim HH, Qin T, Stahl GL, Ezekowitz RA, Carroll MC, Whalen MJ.

J Cereb Blood Flow Metab. 2007 Dec;27(12):1954-64. Epub 2007 Apr 25.

PMID:
17457366
12.

A systems biology analysis of the Drosophila phagosome.

Stuart LM, Boulais J, Charriere GM, Hennessy EJ, Brunet S, Jutras I, Goyette G, Rondeau C, Letarte S, Huang H, Ye P, Morales F, Kocks C, Bader JS, Desjardins M, Ezekowitz RA.

Nature. 2007 Jan 4;445(7123):95-101. Epub 2006 Dec 6.

PMID:
17151602
13.

Activation of the lectin pathway by natural IgM in a model of ischemia/reperfusion injury.

Zhang M, Takahashi K, Alicot EM, Vorup-Jensen T, Kessler B, Thiel S, Jensenius JC, Ezekowitz RA, Moore FD, Carroll MC.

J Immunol. 2006 Oct 1;177(7):4727-34.

14.

Investigations on the involvement of the lectin pathway of complement activation in anaphylaxis.

Windbichler M, Echtenacher B, Takahashi K, Ezekowitz RA, Schwaeble WJ, Jenseniuis JC, Männel DN.

Int Arch Allergy Immunol. 2006;141(1):11-23. Epub 2006 Jun 23.

PMID:
16804320
15.

Characterization of an equine mannose-binding lectin and its roles in disease.

Podolsky MJ, Lasker A, Flaminio MJ, Gowda LD, Ezekowitz RA, Takahashi K.

Biochem Biophys Res Commun. 2006 May 12;343(3):928-36. Epub 2006 Mar 29.

PMID:
16574074
16.

Double-stranded RNA is internalized by scavenger receptor-mediated endocytosis in Drosophila S2 cells.

Ulvila J, Parikka M, Kleino A, Sormunen R, Ezekowitz RA, Kocks C, Rämet M.

J Biol Chem. 2006 May 19;281(20):14370-5. Epub 2006 Mar 10.

17.

Deficiency of mannose-binding lectin greatly increases susceptibility to postburn infection with Pseudomonas aeruginosa.

Møller-Kristensen M, Ip WK, Shi L, Gowda LD, Hamblin MR, Thiel S, Jensenius JC, Ezekowitz RA, Takahashi K.

J Immunol. 2006 Feb 1;176(3):1769-75.

18.

The mannose-binding lectin: a prototypic pattern recognition molecule.

Takahashi K, Ip WE, Michelow IC, Ezekowitz RA.

Curr Opin Immunol. 2006 Feb;18(1):16-23. Epub 2005 Dec 20. Review.

PMID:
16368230
19.

Relative roles of complement factor 3 and mannose-binding lectin in host defense against infection.

Takahashi K, Shi L, Gowda LD, Ezekowitz RA.

Infect Immun. 2005 Dec;73(12):8188-93.

20.

Eater, a transmembrane protein mediating phagocytosis of bacterial pathogens in Drosophila.

Kocks C, Cho JH, Nehme N, Ulvila J, Pearson AM, Meister M, Strom C, Conto SL, Hetru C, Stuart LM, Stehle T, Hoffmann JA, Reichhart JM, Ferrandon D, Rämet M, Ezekowitz RA.

Cell. 2005 Oct 21;123(2):335-46.

21.

The role of the mannose-binding lectin in innate immunity.

Takahashi K, Ezekowitz RA.

Clin Infect Dis. 2005 Nov 15;41 Suppl 7:S440-4. Review.

PMID:
16237644
22.

Response to Staphylococcus aureus requires CD36-mediated phagocytosis triggered by the COOH-terminal cytoplasmic domain.

Stuart LM, Deng J, Silver JM, Takahashi K, Tseng AA, Hennessy EJ, Ezekowitz RA, Moore KJ.

J Cell Biol. 2005 Aug 1;170(3):477-85.

23.

Mannose-binding lectin is a regulator of inflammation that accompanies myocardial ischemia and reperfusion injury.

Walsh MC, Bourcier T, Takahashi K, Shi L, Busche MN, Rother RP, Solomon SD, Ezekowitz RA, Stahl GL.

J Immunol. 2005 Jul 1;175(1):541-6.

24.

Human peptidoglycan recognition protein S is an effector of neutrophil-mediated innate immunity.

Cho JH, Fraser IP, Fukase K, Kusumoto S, Fujimoto Y, Stahl GL, Ezekowitz RA.

Blood. 2005 Oct 1;106(7):2551-8. Epub 2005 Jun 14.

25.

The mannose-binding lectin: an infection susceptibility gene.

Ezekowitz RA, Shi L, Fraser I, Takahashi K.

Adv Exp Med Biol. 2005;560:99-103. Review. No abstract available.

PMID:
15932025
26.

Phagocytosis: elegant complexity.

Stuart LM, Ezekowitz RA.

Immunity. 2005 May;22(5):539-50. Review.

27.

Functional analysis of immune response genes in Drosophila identifies JNK pathway as a regulator of antimicrobial peptide gene expression in S2 cells.

Kallio J, Leinonen A, Ulvila J, Valanne S, Ezekowitz RA, Rämet M.

Microbes Infect. 2005 May;7(5-6):811-9. Epub 2005 Apr 18.

PMID:
15890554
28.

Mannose-binding lectin-deficient mice display defective apoptotic cell clearance but no autoimmune phenotype.

Stuart LM, Takahashi K, Shi L, Savill J, Ezekowitz RA.

J Immunol. 2005 Mar 15;174(6):3220-6. Erratum in: J Immunol. 2005 Sep 1;175(5):3447.

29.

Mannose-binding lectin-deficient mice are susceptible to infection with Staphylococcus aureus.

Shi L, Takahashi K, Dundee J, Shahroor-Karni S, Thiel S, Jensenius JC, Gad F, Hamblin MR, Sastry KN, Ezekowitz RA.

J Exp Med. 2004 May 17;199(10):1379-90.

30.

TLR-independent pattern recognition receptors and anti-inflammatory mechanisms.

Fraser IP, Stuart L, Ezekowitz RA.

J Endotoxin Res. 2004;10(2):120-4. Review.

PMID:
15120003
31.

Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 13-2004. A newborn girl with a large cutaneous lesion, thrombocytopenia, and anemia.

Mulliken JB, Anupindi S, Ezekowitz RA, Mihm MC Jr.

N Engl J Med. 2004 Apr 22;350(17):1764-75. No abstract available.

PMID:
15103004
32.

Mannose-binding lectin deficiency alters the development of fungal asthma: effects on airway response, inflammation, and cytokine profile.

Hogaboam CM, Takahashi K, Ezekowitz RA, Kunkel SL, Schuh JM.

J Leukoc Biol. 2004 May;75(5):805-14. Epub 2004 Feb 3.

33.

Identification of cytoskeletal regulatory proteins required for efficient phagocytosis in Drosophila.

Pearson AM, Baksa K, Rämet M, Protas M, McKee M, Brown D, Ezekowitz RA.

Microbes Infect. 2003 Aug;5(10):815-24.

PMID:
12919849
34.

A case of familial meningococcal disease due to deficiency in mannose-binding lectin (MBL).

Kuipers S, Aerts PC, Cluysenaer OJ, Bartelink AK, Ezekowitz RA, Bax WA, Salimans M, Vandyk H.

Adv Exp Med Biol. 2003;531:351-5. Review.

PMID:
12916805
35.

Role of the mannose-binding lectin in innate immunity.

Ezekowitz RA.

J Infect Dis. 2003 Jun 15;187 Suppl 2:S335-9.

PMID:
12792848
36.

Lack of mannose-binding lectin-A enhances survival in a mouse model of acute septic peritonitis.

Takahashi K, Gordon J, Liu H, Sastry KN, Epstein JE, Motwani M, Laursen I, Thiel S, Jensenius JC, Carroll M, Ezekowitz RA.

Microbes Infect. 2002 Jul;4(8):773-84.

PMID:
12270724
37.

Local opsonization for apoptosis?

Ezekowitz RA.

Nat Immunol. 2002 Jun;3(6):510-2. No abstract available.

PMID:
12032563
38.

Functional genomic analysis of phagocytosis and identification of a Drosophila receptor for E. coli.

Rämet M, Manfruelli P, Pearson A, Mathey-Prevot B, Ezekowitz RA.

Nature. 2002 Apr 11;416(6881):644-8. Epub 2002 Mar 24.

PMID:
11912489
39.

The complement response against an oncolytic virus is species-specific in its activation pathways.

Wakimoto H, Ikeda K, Abe T, Ichikawa T, Hochberg FH, Ezekowitz RA, Pasternack MS, Chiocca EA.

Mol Ther. 2002 Mar;5(3):275-82.

40.

Drosophila scavenger receptor CI is a pattern recognition receptor for bacteria.

Rämet M, Pearson A, Manfruelli P, Li X, Koziel H, Göbel V, Chung E, Krieger M, Ezekowitz RA.

Immunity. 2001 Dec;15(6):1027-38.

41.

Toll-like receptors as sensors of pathogens.

Hallman M, Rämet M, Ezekowitz RA.

Pediatr Res. 2001 Sep;50(3):315-21. Review.

PMID:
11518816
42.

Mannan-binding lectin enhances susceptibility to visceral leishmaniasis.

Santos IK, Costa CH, Krieger H, Feitosa MF, Zurakowski D, Fardin B, Gomes RB, Weiner DL, Harn DA, Ezekowitz RA, Epstein JE.

Infect Immun. 2001 Aug;69(8):5212-5.

43.

Recombinant expression of human mannan-binding lectin.

Vorup-Jensen T, Sørensen ES, Jensen UB, Schwaeble W, Kawasaki T, Ma Y, Uemura K, Wakamiya N, Suzuki Y, Jensen TG, Takahashi K, Ezekowitz RA, Thiel S, Jensenius JC.

Int Immunopharmacol. 2001 Apr;1(4):677-87.

PMID:
11357880
44.

What is the best way to treat inherited disorders?

Ezekowitz RA.

N Engl J Med. 2001 Mar 22;344(12):926-7. No abstract available.

PMID:
11259728
45.

Pneumocystis carinii enhances soluble mannose receptor production by macrophages.

Fraser IP, Takahashi K, Koziel H, Fardin B, Harmsen A, Ezekowitz RA.

Microbes Infect. 2000 Sep;2(11):1305-10.

PMID:
11018446
46.

Update on chronic granulomatous disease: the concept of the near-normal host.

Ezekowitz RA.

Curr Clin Top Infect Dis. 2000;20:325-34. Review. No abstract available.

PMID:
10943531
47.
48.

Enhanced antiviral and opsonic activity of a human mannose-binding lectin and surfactant protein D chimera.

White MR, Crouch E, Chang D, Sastry K, Guo N, Engelich G, Takahashi K, Ezekowitz RA, Hartshorn KL.

J Immunol. 2000 Aug 15;165(4):2108-15.

49.

Development of chimeric collectins with enhanced activity against influenza A virus.

Hartshorn KL, White MR, Ezekowitz RA, Sastry K, Crouch E.

Adv Exp Med Biol. 2000;479:49-59. Review. No abstract available.

PMID:
10897409
50.

Association of familial deficiency of mannose-binding lectin and meningococcal disease.

Bax WA, Cluysenaer OJ, Bartelink AK, Aerts PC, Ezekowitz RA, van Dijk H.

Lancet. 1999 Sep 25;354(9184):1094-5.

PMID:
10509505

Supplemental Content

Loading ...
Support Center