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Impact of cardiology follow-up care on treatment and outcomes of patients with new atrial fibrillation discharged from the emergency department.

Hawkins NM, Scheuermeyer FX, Youngson E, Sandhu RK, Ezekowitz JA, Kaul P, McAlister FA.

Europace. 2019 Dec 4. pii: euz302. doi: 10.1093/europace/euz302. [Epub ahead of print]


Heart failure treatment and the art of medical decision making.

McAlister FA, Ezekowitz JA, Armstrong PW.

Eur J Heart Fail. 2019 Nov 25. doi: 10.1002/ejhf.1655. [Epub ahead of print] No abstract available.


Eligibility of sodium-glucose co-transporter-2 inhibitors among patients with diabetes mellitus admitted for heart failure.

Sharma A, Wu J, Ezekowitz JA, Felker GM, Udell JA, Heidenreich PA, Fonarow GC, Mahaffey KW, Hernandez AF, DeVore AD.

ESC Heart Fail. 2019 Nov 20. doi: 10.1002/ehf2.12528. [Epub ahead of print]


All for one, but not one for all.

Ezekowitz JA.

Eur Heart J. 2019 Nov 9. pii: ehz808. doi: 10.1093/eurheartj/ehz808. [Epub ahead of print] No abstract available.


The hospital frailty risk score in patients with heart failure is strongly associated with outcomes but less so with pharmacotherapy.

McAlister FA, Savu A, Ezekowitz JA, Armstrong PW, Kaul P.

J Intern Med. 2019 Oct 29. doi: 10.1111/joim.13002. [Epub ahead of print]


Is plasma renin activity associated with worse outcomes in acute heart failure? A secondary analysis from the BLAST-AHF trial.

Rachwan RJ, Butler J, Collins SP, Cotter G, Davison BA, Senger S, Ezekowitz JA, Filippatos G, Levy PD, Metra M, Ponikowski P, Teerlink JR, Voors AA, de Boer RA, Soergel DG, Felker GM, Pang PS.

Eur J Heart Fail. 2019 Oct 23. doi: 10.1002/ejhf.1607. [Epub ahead of print]


Role of Sodium-Glucose Cotransporter-2 Inhibition in the Treatment of Adults With Heart Failure.

Sharma A, Ezekowitz JA.

Can J Diabetes. 2019 Aug 23. pii: S1499-2671(19)30616-1. doi: 10.1016/j.jcjd.2019.08.012. [Epub ahead of print] Review.


2017 Guidelines for the management of heart failure by pharmacists.

Beique LC, Ezekowitz JA, O'Meara E, McDonald M, Koshman SL.

Can Pharm J (Ott). 2019 Jul 2;152(5):301-316. doi: 10.1177/1715163519853307. eCollection 2019 Sep-Oct. No abstract available.


Quantification of lung water in heart failure using cardiovascular magnetic resonance imaging.

Thompson RB, Chow K, Pagano JJ, Sekowski V, Michelakis ED, Tymchak W, Haykowsky MJ, Ezekowitz JA, Oudit GY, Dyck JRB, Kaul P, Savu A, Paterson DI.

J Cardiovasc Magn Reson. 2019 Sep 12;21(1):58. doi: 10.1186/s12968-019-0567-y.


Trends in the Explanatory or Pragmatic Nature of Cardiovascular Clinical Trials Over 2 Decades.

Sepehrvand N, Alemayehu W, Das D, Gupta AK, Gouda P, Ghimire A, Du AX, Hatami S, Babadagli HE, Verma S, Kashour Z, Ezekowitz JA.

JAMA Cardiol. 2019 Sep 1. doi: 10.1001/jamacardio.2019.3604. [Epub ahead of print]


Empirical Insights When Defining the Population Burden of Atrial Fibrillation and Oral Anticoagulation Utilization Using Administrative Data.

Hawkins NM, Daniele PR, Humphries KH, Ezekowitz JA, McAlister FA, Sandhu RK, Kaul P.

Can J Cardiol. 2019 Oct;35(10):1412-1415. doi: 10.1016/j.cjca.2019.05.009. Epub 2019 May 15.


Natriuretic Peptide Response and Outcomes in Chronic Heart Failure With Reduced Ejection Fraction.

Januzzi JL Jr, Ahmad T, Mulder H, Coles A, Anstrom KJ, Adams KF, Ezekowitz JA, Fiuzat M, Houston-Miller N, Mark DB, Piña IL, Passmore G, Whellan DJ, Cooper LS, Leifer ES, Desvigne-Nickens P, Felker GM, O'Connor CM.

J Am Coll Cardiol. 2019 Sep 3;74(9):1205-1217. doi: 10.1016/j.jacc.2019.06.055.


Frequency, predictors, and prognosis of ejection fraction improvement in heart failure: an echocardiogram-based registry study.

Ghimire A, Fine N, Ezekowitz JA, Howlett J, Youngson E, McAlister FA.

Eur Heart J. 2019 Jul 1;40(26):2110-2117. doi: 10.1093/eurheartj/ehz233.


High vs. low oxygen therapy in patients with acute heart failure: HiLo-HF pilot trial.

Sepehrvand N, Alemayehu W, Rowe BH, McAlister FA, van Diepen S, Stickland M, Ezekowitz JA.

ESC Heart Fail. 2019 Aug;6(4):667-677. doi: 10.1002/ehf2.12448. Epub 2019 May 17.


External Validation of the H2F-PEF Model in Diagnosing Patients With Heart Failure and Preserved Ejection Fraction.

Sepehrvand N, Alemayehu W, Dyck GJB, Dyck JRB, Anderson T, Howlett J, Paterson I, McAlister FA, Ezekowitz JA.

Circulation. 2019 May 14;139(20):2377-2379. doi: 10.1161/CIRCULATIONAHA.118.038594. No abstract available.


Incremental costs of high intensive care utilisation in patients hospitalised with heart failure.

van Diepen S, Tran DT, Ezekowitz JA, Schnell G, Wiley BM, Morrow DA, McAlister FA, Kaul P.

Eur Heart J Acute Cardiovasc Care. 2019 Oct;8(7):660-666. doi: 10.1177/2048872619845282. Epub 2019 Apr 12.


Clinical factors related to morbidity and mortality in high-risk heart failure patients: the GUIDE-IT predictive model and risk score.

O'Connor C, Fiuzat M, Mulder H, Coles A, Ahmad T, Ezekowitz JA, Adams KF, Piña IL, Anstrom KJ, Cooper LS, Mark DB, Whellan DJ, Januzzi JL Jr, Leifer ES, Felker GM.

Eur J Heart Fail. 2019 Jun;21(6):770-778. doi: 10.1002/ejhf.1450. Epub 2019 Mar 27.


The Effects of Resveratrol in Patients with Cardiovascular Disease and Heart Failure: A Narrative Review.

Dyck GJB, Raj P, Zieroth S, Dyck JRB, Ezekowitz JA.

Int J Mol Sci. 2019 Feb 19;20(4). pii: E904. doi: 10.3390/ijms20040904. Review.


Efficacy and Safety of Apixaban Versus Warfarin in Patients With Atrial Fibrillation and Extremes in Body Weight.

Hohnloser SH, Fudim M, Alexander JH, Wojdyla DM, Ezekowitz JA, Hanna M, Atar D, Hijazi Z, Bahit MC, Al-Khatib SM, Lopez-Sendon JL, Wallentin L, Granger CB, Lopes RD.

Circulation. 2019 May 14;139(20):2292-2300. doi: 10.1161/CIRCULATIONAHA.118.037955.


Creating order out of chaos: quality of care in heart failure.

Ezekowitz JA.

Heart. 2019 Mar;105(6):429-430. doi: 10.1136/heartjnl-2018-314526. Epub 2019 Jan 31. No abstract available.


Update on the diagnosis and management of acute heart failure.

Gouda P, Ezekowitz JA.

Curr Opin Cardiol. 2019 Mar;34(2):202-206. doi: 10.1097/HCO.0000000000000594.


Titration and Tolerability of Sacubitril/Valsartan for Patients With Heart Failure in Clinical Practice.

Du AX, Westerhout CM, McAlister FA, Shanks M, Oudit GY, Paterson DI, Hanninen M, Thomas J, Ezekowitz JA.

J Cardiovasc Pharmacol. 2019 Mar;73(3):149-154. doi: 10.1097/FJC.0000000000000643.


Obesity paradox on outcome in atrial fibrillation maintained even considering the prognostic influence of biomarkers: insights from the ARISTOTLE trial.

Sandhu RK, Ezekowitz JA, Hijazi Z, Westerbergh J, Aulin J, Alexander JH, Granger CB, Halvorsen S, Hanna MS, Lopes RD, Siegbahn A, Wallentin L.

Open Heart. 2018 Nov 1;5(2):e000908. doi: 10.1136/openhrt-2018-000908. eCollection 2018.


Economic and Quality-of-Life Outcomes of Natriuretic Peptide-Guided Therapy for Heart Failure.

Mark DB, Cowper PA, Anstrom KJ, Sheng S, Daniels MR, Knight JD, Baloch KN, Davidson-Ray L, Fiuzat M, Januzzi JL Jr, Whellan DJ, Piña IL, Ezekowitz JA, Adams KF, Cooper LS, O'Connor CM, Felker GM.

J Am Coll Cardiol. 2018 Nov 27;72(21):2551-2562. doi: 10.1016/j.jacc.2018.08.2184.


Impact of contrast echocardiography on accurate discrimination of specific degree of left ventricular systolic dysfunction and comparison with cardiac magnetic resonance imaging.

Alherbish A, Becher H, Alemayehu W, Paterson DI, Butler CR, Anderson TJ, Ezekowitz JA, Shanks M; Alberta HEART investigators.

Echocardiography. 2018 Nov;35(11):1746-1754. doi: 10.1111/echo.14152. Epub 2018 Oct 30.


Comparison of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Management Strategies Before Cardiac Surgery: A Pilot Randomized Controlled Registry Trial.

van Diepen S, Norris CM, Zheng Y, Nagendran J, Graham MM, Gaete Ortega D, Townsend DR, Ezekowitz JA, Bagshaw SM.

J Am Heart Assoc. 2018 Oct 16;7(20):e009917. doi: 10.1161/JAHA.118.009917.


Relationship Between Enrolling Country Income Level and Patient Profile, Protocol Completion, and Trial End Points.

Greene SJ, Hernandez AF, Sun JL, Butler J, Armstrong PW, Ezekowitz JA, Zannad F, Ferreira JP, Coles A, Metra M, Voors AA, Califf RM, O'Connor CM, Mentz RJ.

Circ Cardiovasc Qual Outcomes. 2018 Oct;11(10):e004783. doi: 10.1161/CIRCOUTCOMES.118.004783.


Canadian Cardiovascular Harmonized National Guidelines Endeavour (C-CHANGE) guideline for the prevention and management of cardiovascular disease in primary care: 2018 update.

Tobe SW, Stone JA, Anderson T, Bacon S, Cheng AYY, Daskalopoulou SS, Ezekowitz JA, Gregoire JC, Gubitz G, Jain R, Keshavjee K, Lindsay P, L'Abbe M, Lau DCW, Leiter LA, O'Meara E, Pearson GJ, Rabi DM, Sherifali D, Selby P, Tu JV, Wharton S, Walker KM, Hua-Stewart D, Liu PP.

CMAJ. 2018 Oct 9;190(40):E1192-E1206. doi: 10.1503/cmaj.180194. No abstract available.


Acute Coronary Syndromes and Heart Failure Critical Care Units Utilization and Outcomes in Teaching and Community Hospitals: A National Population-Based Analysis.

Verma S, Kaul P, Lin M, Ezekowitz JA, Zygun DA, Fordyce CB, Wang TY, McAlister FA, van Diepen S.

Can J Cardiol. 2018 Oct;34(10):1365-1368. doi: 10.1016/j.cjca.2018.07.419. Epub 2018 Jul 29.


Oxygen therapy in acute myocardial infarctions: do we need to re-evaluate its necessity?

Sepehrvand N, Ezekowitz JA.

Expert Rev Cardiovasc Ther. 2018 Oct;16(10):693-694. doi: 10.1080/14779072.2018.1523719. Epub 2018 Sep 19. No abstract available.


Rationale and design of the Study of Dietary Intervention Under 100 MMOL in Heart Failure (SODIUM-HF).

Colin-Ramirez E, Ezekowitz JA; SODIUM-HF investigators.

Am Heart J. 2018 Nov;205:87-96. doi: 10.1016/j.ahj.2018.08.005. Epub 2018 Aug 16.


Relation of Volume Overload to Clinical Outcomes in Acute Heart Failure (From ASCEND-HF).

Fudim M, Parikh KS, Dunning A, DeVore AD, Mentz RJ, Schulte PJ, Armstrong PW, Ezekowitz JA, Tang WHW, McMurray JJV, Voors AA, Drazner MH, O'Connor CM, Hernandez AF, Patel CB.

Am J Cardiol. 2018 Nov 1;122(9):1506-1512. doi: 10.1016/j.amjcard.2018.07.023. Epub 2018 Aug 3.


Initial Rhythm and Resuscitation Outcomes for Patients Developing Cardiac Arrest in Hospital: Data From Low-Middle Income Country.

Ngunga LM, Yonga G, Wachira B, Ezekowitz JA.

Glob Heart. 2018 Dec;13(4):255-260. doi: 10.1016/j.gheart.2018.07.001. Epub 2018 Aug 18.


Is incentivising stroke prevention therapy in atrial fibrillation the key?

Sandhu RK, Ezekowitz JA.

Heart. 2019 Jan;105(1):4-5. doi: 10.1136/heartjnl-2018-313402. Epub 2018 Jul 10. No abstract available.


Influence of hospital volume on outcomes for patients with heart failure: Evidence from a Canadian national cohort study.

McAlister FA, Youngson E, van Diepen S, Ezekowitz JA, Kaul P.

Am Heart J. 2018 Aug;202:148-150. doi: 10.1016/j.ahj.2018.05.014. Epub 2018 May 27.


The high cost of critical care unit over-utilization for patients with NSTE ACS.

van Diepen S, Tran DT, Ezekowitz JA, Zygun DA, Katz JN, Lopes RD, Newby LK, McAlister FA, Kaul P.

Am Heart J. 2018 Aug;202:84-88. doi: 10.1016/j.ahj.2018.05.003. Epub 2018 May 19.


Use of Biomarkers to Predict Specific Causes of Death in Patients With Atrial Fibrillation.

Sharma A, Hijazi Z, Andersson U, Al-Khatib SM, Lopes RD, Alexander JH, Held C, Hylek EM, Leonardi S, Hanna M, Ezekowitz JA, Siegbahn A, Granger CB, Wallentin L.

Circulation. 2018 Oct 16;138(16):1666-1676. doi: 10.1161/CIRCULATIONAHA.118.034125.


Examining the Influence of Component Outcomes on the Composite at the Design Stage.

Brown PM, Ezekowitz JA.

Circ Cardiovasc Qual Outcomes. 2018 Jun;11(6):e004419. doi: 10.1161/CIRCOUTCOMES.117.004419. No abstract available.


Trends in Noncardiovascular Comorbidities Among Patients Hospitalized for Heart Failure: Insights From the Get With The Guidelines-Heart Failure Registry.

Sharma A, Zhao X, Hammill BG, Hernandez AF, Fonarow GC, Felker GM, Yancy CW, Heidenreich PA, Ezekowitz JA, DeVore AD.

Circ Heart Fail. 2018 Jun;11(6):e004646. doi: 10.1161/CIRCHEARTFAILURE.117.004646.


Implantable cardioverter-defibrillators in heart failure patients with reduced ejection fraction and diabetes.

Sharma A, Al-Khatib SM, Ezekowitz JA, Cooper LB, Fordyce CB, Michael Felker G, Bardy GH, Poole JE, Thomas Bigger J, Buxton AE, Moss AJ, Friedman DJ, Lee KL, Steinman R, Dorian P, Cappato R, Kadish AH, Kudenchuk PJ, Mark DB, Peterson ED, Inoue LYT, Sanders GD.

Eur J Heart Fail. 2018 Jun;20(6):1031-1038. doi: 10.1002/ejhf.1192. Epub 2018 May 15.


Reply to McClure et al.-Reader Commentary on 2017 Comprehensive Update of the Canadian Cardiovascular Society Guidelines for the Management of Heart Failure.

Ezekowitz JA, McMurtry MS.

Can J Cardiol. 2018 Jun;34(6):813.e3. doi: 10.1016/j.cjca.2018.03.004. Epub 2018 Mar 16. No abstract available.


Ambulance use, distance and outcomes in patients with suspected cardiovascular disease: a registry-based geographic information system study.

Sepehrvand N, Alemayehu W, Kaul P, Pelletier R, Bello AK, Welsh RC, Armstrong PW, Ezekowitz JA.

Eur Heart J Acute Cardiovasc Care. 2018 Apr 1:2048872618769872. doi: 10.1177/2048872618769872. [Epub ahead of print]


Effects of supplemental oxygen therapy in patients with suspected acute myocardial infarction: a meta-analysis of randomised clinical trials.

Sepehrvand N, James SK, Stub D, Khoshnood A, Ezekowitz JA, Hofmann R.

Heart. 2018 Oct;104(20):1691-1698. doi: 10.1136/heartjnl-2018-313089. Epub 2018 Mar 29. Review.


Is Time of the Essence? The Impact of Time of Hospital Presentation in Acute Heart Failure: Insights From ASCEND-HF Trial.

Cerbin LP, Ambrosy AP, Greene SJ, Armstrong PW, Butler J, Coles A, DeVore AD, Ezekowitz JA, Hernandez AF, Metra M, Starling RC, Tang W, Teerlink JR, Voors AA, Wu A, O'Connor CM, Mentz RJ.

JACC Heart Fail. 2018 Apr;6(4):298-307. doi: 10.1016/j.jchf.2018.01.018. Epub 2018 Mar 7.


Interaction of Body Mass Index on the Association Between N-Terminal-Pro-b-Type Natriuretic Peptide and Morbidity and Mortality in Patients With Acute Heart Failure: Findings From ASCEND-HF (Acute Study of Clinical Effectiveness of Nesiritide in Decompensated Heart Failure).

Bhatt AS, Cooper LB, Ambrosy AP, Clare RM, Coles A, Joyce E, Krishnamoorthy A, Butler J, Felker GM, Ezekowitz JA, Armstrong PW, Hernandez AF, O'Connor CM, Mentz RJ.

J Am Heart Assoc. 2018 Feb 3;7(3). pii: e006740. doi: 10.1161/JAHA.117.006740.


Use of Direct Oral Anticoagulants in Canadian Primary Care Practice 2010-2015: A Cohort Study From the Canadian Primary Care Sentinel Surveillance Network.

McAlister FA, Garrison S, Kosowan L, Ezekowitz JA, Singer A.

J Am Heart Assoc. 2018 Jan 26;7(3). pii: e007603. doi: 10.1161/JAHA.117.007603.


Prediction of Early Adverse Events in Emergency Department Patients With Acute Heart Failure: A Systematic Review.

Michaud AM, Parker SIA, Ganshorn H, Ezekowitz JA, McRae AD.

Can J Cardiol. 2018 Feb;34(2):168-179. doi: 10.1016/j.cjca.2017.09.004. Epub 2017 Sep 12. Review.


Sudden cardiac death after acute heart failure hospital admission: insights from ASCEND-HF.

Pokorney SD, Al-Khatib SM, Sun JL, Schulte P, O'Connor CM, Teerlink JR, Armstrong PW, Ezekowitz JA, Starling RC, Voors AA, Velazquez EJ, Hernandez AF, Mentz RJ.

Eur J Heart Fail. 2018 Mar;20(3):525-532. doi: 10.1002/ejhf.1078. Epub 2017 Dec 20.


Impact of climate and air pollution on acute coronary syndromes: an update from the European Society of Cardiology Congress 2017.

Kaluzna-Oleksy M, Aunan K, Rao-Skirbekk S, Kjellstrom T, Ezekowitz JA, Agewall S, Atar D.

Scand Cardiovasc J. 2018 Feb;52(1):1-3. doi: 10.1080/14017431.2017.1405069. Epub 2017 Dec 4. No abstract available.


2017 Comprehensive Update of the Canadian Cardiovascular Society Guidelines for the Management of Heart Failure.

Ezekowitz JA, O'Meara E, McDonald MA, Abrams H, Chan M, Ducharme A, Giannetti N, Grzeslo A, Hamilton PG, Heckman GA, Howlett JG, Koshman SL, Lepage S, McKelvie RS, Moe GW, Rajda M, Swiggum E, Virani SA, Zieroth S, Al-Hesayen A, Cohen-Solal A, D'Astous M, De S, Estrella-Holder E, Fremes S, Green L, Haddad H, Harkness K, Hernandez AF, Kouz S, LeBlanc MH, Masoudi FA, Ross HJ, Roussin A, Sussex B.

Can J Cardiol. 2017 Nov;33(11):1342-1433. doi: 10.1016/j.cjca.2017.08.022. Epub 2017 Sep 6.


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