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Items: 1 to 50 of 56

1.

Prediction of Minimum Inhibitory Concentrations of Antimicrobials for Neisseria gonorrhoeae Using Whole-Genome Sequencing.

Eyre DW, Golparian D, Unemo M.

Methods Mol Biol. 2019;1997:59-76. doi: 10.1007/978-1-4939-9496-0_4.

PMID:
31119617
2.

Antimicrobial Resistance in Neisseria gonorrhoeae and Treatment of Gonorrhea.

Unemo M, Golparian D, Eyre DW.

Methods Mol Biol. 2019;1997:37-58. doi: 10.1007/978-1-4939-9496-0_3.

PMID:
31119616
3.

Clostridium difficile trehalose metabolism variants are common and not associated with adverse patient outcomes when variably present in the same lineage.

Eyre DW, Didelot X, Buckley AM, Freeman J, Moura IB, Crook DW, Peto TEA, Walker AS, Wilcox MH, Dingle KE.

EBioMedicine. 2019 May;43:347-355. doi: 10.1016/j.ebiom.2019.04.038. Epub 2019 Apr 27.

4.

Male gender is an independent predictor for worse survival and relapse in a large, consecutive cohort of elderly DLBCL patients treated with R-CHOP.

Eyre TA, Martinez-Calle N, Hildyard C, Eyre DW, Plaschkes H, Griffith J, Wolf J, Fields PA, Gunawan A, Oliver R, Booth S, McMillan A, Fox CP, Bishton M, Collins GP, Hatton CSR.

Br J Haematol. 2019 Apr 24. doi: 10.1111/bjh.15927. [Epub ahead of print] No abstract available.

PMID:
31020646
5.

A Role for Tetracycline Selection in Recent Evolution of Agriculture-Associated Clostridium difficile PCR Ribotype 078.

Dingle KE, Didelot X, Quan TP, Eyre DW, Stoesser N, Marwick CA, Coia J, Brown D, Buchanan S, Ijaz UZ, Goswami C, Douce G, Fawley WN, Wilcox MH, Peto TEA, Walker AS, Crook DW.

MBio. 2019 Mar 12;10(2). pii: e02790-18. doi: 10.1128/mBio.02790-18.

6.

Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018.

Eyre DW, Town K, Street T, Barker L, Sanderson N, Cole MJ, Mohammed H, Pitt R, Gobin M, Irish C, Gardiner D, Sedgwick J, Beck C, Saunders J, Turbitt D, Cook C, Phin N, Nathan B, Horner P, Fifer H.

Euro Surveill. 2019 Mar;24(10). doi: 10.2807/1560-7917.ES.2019.24.10.1900147.

7.

Candida auris in an Intensive Care Setting. Reply.

Eyre DW, Butcher L, Jeffery KJM.

N Engl J Med. 2019 Feb 28;380(9):891. doi: 10.1056/NEJMc1900112. No abstract available.

PMID:
30811924
8.

Impact of intended and relative dose intensity of R-CHOP in a large, consecutive cohort of elderly diffuse large B-cell lymphoma patients treated with curative intent: no difference in cumulative incidence of relapse comparing patients by age.

Eyre TA, Martinez-Calle N, Hildyard C, Eyre DW, Plaschkes H, Griffith J, Wolf J, Fields P, Gunawan A, Oliver R, Djebbari F, Booth S, McMillan A, Fox CP, Bishton MJ, Collins GP, Hatton CSR.

J Intern Med. 2019 Jun;285(6):681-692. doi: 10.1111/joim.12889. Epub 2019 Apr 11.

PMID:
30811713
9.

WGS to determine the extent of Clostridioides difficile transmission in a high incidence setting in North Wales in 2015.

Eyre DW, Shaw R, Adams H, Cooper T, Crook DW, Griffin RM, Mannion P, Morgan M, Morris T, Perry M, Jones S, Peto TEA, Sutton J, Walker AS, Williams D, Craine N.

J Antimicrob Chemother. 2019 Apr 1;74(4):1092-1100. doi: 10.1093/jac/dky523.

PMID:
30561656
10.

A Candida auris Outbreak and Its Control in an Intensive Care Setting.

Eyre DW, Sheppard AE, Madder H, Moir I, Moroney R, Quan TP, Griffiths D, George S, Butcher L, Morgan M, Newnham R, Sunderland M, Clarke T, Foster D, Hoffman P, Borman AM, Johnson EM, Moore G, Brown CS, Walker AS, Peto TEA, Crook DW, Jeffery KJM.

N Engl J Med. 2018 Oct 4;379(14):1322-1331. doi: 10.1056/NEJMoa1714373.

11.

Real-time analysis of nanopore-based metagenomic sequencing from infected orthopaedic devices.

Sanderson ND, Street TL, Foster D, Swann J, Atkins BL, Brent AJ, McNally MA, Oakley S, Taylor A, Peto TEA, Crook DW, Eyre DW.

BMC Genomics. 2018 Sep 27;19(1):714. doi: 10.1186/s12864-018-5094-y.

12.

Gonorrhoea treatment failure caused by a Neisseria gonorrhoeae strain with combined ceftriaxone and high-level azithromycin resistance, England, February 2018.

Eyre DW, Sanderson ND, Lord E, Regisford-Reimmer N, Chau K, Barker L, Morgan M, Newnham R, Golparian D, Unemo M, Crook DW, Peto TE, Hughes G, Cole MJ, Fifer H, Edwards A, Andersson MI.

Euro Surveill. 2018 Jul;23(27). doi: 10.2807/1560-7917.ES.2018.23.27.1800323.

13.

Clostridium difficile: Investigating Transmission Patterns Between Infected and Colonized Patients Using Whole Genome Sequencing.

Kong LY, Eyre DW, Corbeil J, Raymond F, Walker AS, Wilcox MH, Crook DW, Michaud S, Toye B, Frost E, Dendukuri N, Schiller I, Bourgault AM, Dascal A, Oughton M, Longtin Y, Poirier L, Brassard P, Turgeon N, Gilca R, Loo VG.

Clin Infect Dis. 2019 Jan 7;68(2):204-209. doi: 10.1093/cid/ciy457.

14.

Patient and Strain Characteristics Associated With Clostridium difficile Transmission and Adverse Outcomes.

Martin JSH, Eyre DW, Fawley WN, Griffiths D, Davies K, Mawer DPC, Peto TEA, Crook DW, Walker AS, Wilcox MH.

Clin Infect Dis. 2018 Oct 15;67(9):1379-1387. doi: 10.1093/cid/ciy302.

15.

Two Distinct Patterns of Clostridium difficile Diversity Across Europe Indicating Contrasting Routes of Spread.

Eyre DW, Davies KA, Davis G, Fawley WN, Dingle KE, De Maio N, Karas A, Crook DW, Peto TEA, Walker AS, Wilcox MH; EUCLID Study Group .

Clin Infect Dis. 2018 Sep 14;67(7):1035-1044. doi: 10.1093/cid/ciy252.

16.

BugMat and FindNeighbour: command line and server applications for investigating bacterial relatedness.

Mazariegos-Canellas O, Do T, Peto T, Eyre DW, Underwood A, Crook D, Wyllie DH.

BMC Bioinformatics. 2017 Nov 13;18(1):477. doi: 10.1186/s12859-017-1907-2.

17.

Whole genome sequencing of Neisseria gonorrhoeae reveals transmission clusters involving patients of mixed HIV serostatus.

Peters J, Cresswell F, Amor L, Cole K, Dean G, Didelot X, De Silva D, Eyre DW, Paul J.

Sex Transm Infect. 2018 Mar;94(2):138-143. doi: 10.1136/sextrans-2017-053198. Epub 2017 Oct 11.

18.

Covert dissemination of carbapenemase-producing Klebsiella pneumoniae (KPC) in a successfully controlled outbreak: long- and short-read whole-genome sequencing demonstrate multiple genetic modes of transmission.

Martin J, Phan HTT, Findlay J, Stoesser N, Pankhurst L, Navickaite I, De Maio N, Eyre DW, Toogood G, Orsi NM, Kirby A, Young N, Turton JF, Hill RLR, Hopkins KL, Woodford N, Peto TEA, Walker AS, Crook DW, Wilcox MH.

J Antimicrob Chemother. 2017 Nov 1;72(11):3025-3034. doi: 10.1093/jac/dkx264.

19.

Results of a multicentre UK-wide retrospective study evaluating the efficacy of brentuximab vedotin in relapsed, refractory classical Hodgkin lymphoma in the transplant naive setting.

Eyre TA, Phillips EH, Linton KM, Arumainathan A, Kassam S, Gibb A, Allibone S, Radford J, Peggs K, Burton C, Stewart G, LeDieu R, Booth C, Osborne WL, Miall F, Eyre DW, Ardeshna KM, Collins GP.

Br J Haematol. 2017 Nov;179(3):471-479. doi: 10.1111/bjh.14898. Epub 2017 Aug 31. Erratum in: Br J Haematol. 2018 Jan;180(2):309.

PMID:
28857136
20.

Epidemiology of Clostridium difficile in infants in Oxfordshire, UK: Risk factors for colonization and carriage, and genetic overlap with regional C. difficile infection strains.

Stoesser N, Eyre DW, Quan TP, Godwin H, Pill G, Mbuvi E, Vaughan A, Griffiths D, Martin J, Fawley W, Dingle KE, Oakley S, Wanelik K, Finney JM, Kachrimanidou M, Moore CE, Gorbach S, Riley TV, Crook DW, Peto TEA, Wilcox MH, Walker AS; Modernising Medical Microbiology Informatics Group (MMMIG).

PLoS One. 2017 Aug 16;12(8):e0182307. doi: 10.1371/journal.pone.0182307. eCollection 2017.

21.

Comparison of Control of Clostridium difficile Infection in Six English Hospitals Using Whole-Genome Sequencing.

Eyre DW, Fawley WN, Rajgopal A, Settle C, Mortimer K, Goldenberg SD, Dawson S, Crook DW, Peto TEA, Walker AS, Wilcox MH.

Clin Infect Dis. 2017 Aug 1;65(3):433-441. doi: 10.1093/cid/cix338.

22.

Molecular Diagnosis of Orthopedic-Device-Related Infection Directly from Sonication Fluid by Metagenomic Sequencing.

Street TL, Sanderson ND, Atkins BL, Brent AJ, Cole K, Foster D, McNally MA, Oakley S, Peto L, Taylor A, Peto TEA, Crook DW, Eyre DW.

J Clin Microbiol. 2017 Aug;55(8):2334-2347. doi: 10.1128/JCM.00462-17. Epub 2017 May 10.

23.

Clostridium difficile in England: can we stop washing our hands? - Authors' reply.

Eyre DW, Dingle KE, Didelot X, Quan TP, Peto TEA, Wilcox MH, Walker AS, Crook DW.

Lancet Infect Dis. 2017 May;17(5):478-479. doi: 10.1016/S1473-3099(17)30185-8. No abstract available.

24.

Results of a multicentre UK-wide compassionate use programme evaluating the efficacy of idelalisib monotherapy in relapsed, refractory follicular lymphoma.

Eyre TA, Osborne WL, Gallop-Evans E, Ardeshna KM, Kassam S, Sadullah S, Sidra G, Culligan D, Arumainathan A, Shankara P, Bowles KM, Eyre DW, Peng YY, Pettengell R, Bloor A, Vandenberghe E, Collins GP.

Br J Haematol. 2018 May;181(4):555-559. doi: 10.1111/bjh.14665. Epub 2017 Mar 24. No abstract available.

PMID:
28342183
25.

WGS to predict antibiotic MICs for Neisseria gonorrhoeae.

Eyre DW, De Silva D, Cole K, Peters J, Cole MJ, Grad YH, Demczuk W, Martin I, Mulvey MR, Crook DW, Walker AS, Peto TEA, Paul J.

J Antimicrob Chemother. 2017 Jul 1;72(7):1937-1947. doi: 10.1093/jac/dkx067.

26.

Contribution to Clostridium Difficile Transmission of Symptomatic Patients With Toxigenic Strains Who Are Fecal Toxin Negative.

Mawer DPC, Eyre DW, Griffiths D, Fawley WN, Martin JSH, Quan TP, Peto TEA, Crook DW, Walker AS, Wilcox MH.

Clin Infect Dis. 2017 May 1;64(9):1163-1170. doi: 10.1093/cid/cix079.

27.

Genomic analysis of urogenital and rectal Neisseria meningitidis isolates reveals encapsulated hyperinvasive meningococci and coincident multidrug-resistant gonococci.

Harrison OB, Cole K, Peters J, Cresswell F, Dean G, Eyre DW, Paul J, Maiden MC.

Sex Transm Infect. 2017 Sep;93(6):445-451. doi: 10.1136/sextrans-2016-052781. Epub 2017 Jan 30.

28.

Effects of control interventions on Clostridium difficile infection in England: an observational study.

Dingle KE, Didelot X, Quan TP, Eyre DW, Stoesser N, Golubchik T, Harding RM, Wilson DJ, Griffiths D, Vaughan A, Finney JM, Wyllie DH, Oakley SJ, Fawley WN, Freeman J, Morris K, Martin J, Howard P, Gorbach S, Goldstein EJC, Citron DM, Hopkins S, Hope R, Johnson AP, Wilcox MH, Peto TEA, Walker AS, Crook DW; Modernising Medical Microbiology Informatics Group.

Lancet Infect Dis. 2017 Apr;17(4):411-421. doi: 10.1016/S1473-3099(16)30514-X. Epub 2017 Jan 25.

29.

Transmission of Staphylococcus aureus between health-care workers, the environment, and patients in an intensive care unit: a longitudinal cohort study based on whole-genome sequencing.

Price JR, Cole K, Bexley A, Kostiou V, Eyre DW, Golubchik T, Wilson DJ, Crook DW, Walker AS, Peto TEA, Llewelyn MJ, Paul J; Modernising Medical Microbiology informatics group.

Lancet Infect Dis. 2017 Feb;17(2):207-214. doi: 10.1016/S1473-3099(16)30413-3. Epub 2016 Nov 16.

30.

Whole-genome sequencing to determine transmission of Neisseria gonorrhoeae: an observational study.

De Silva D, Peters J, Cole K, Cole MJ, Cresswell F, Dean G, Dave J, Thomas DR, Foster K, Waldram A, Wilson DJ, Didelot X, Grad YH, Crook DW, Peto TE, Walker AS, Paul J, Eyre DW.

Lancet Infect Dis. 2016 Nov;16(11):1295-1303. doi: 10.1016/S1473-3099(16)30157-8. Epub 2016 Jul 12.

31.

Results of a multicentre UK-wide retrospective study evaluating the efficacy of pixantrone in relapsed, refractory diffuse large B cell lymphoma.

Eyre TA, Linton KM, Rohman P, Kothari J, Cwynarski K, Ardeshna K, Bailey C, Osborne WL, Rowntree C, Eden D, Shankara P, Eyre DW, Jasani P, Chaidos A, Collins GP, Hatton CS.

Br J Haematol. 2016 Jun;173(6):896-904. doi: 10.1111/bjh.14021. Epub 2016 Mar 9.

PMID:
26956150
32.

Results of a large retrospective analysis of the effect of intended dose intensity of R-CHOP on outcome in a cohort of consecutive, unselected elderly patients with de novo diffuse large B cell lymphoma.

Eyre TA, Salisbury R, Eyre DW, Watson C, Collins GP, Hatton CS.

Br J Haematol. 2016 May;173(3):487-91. doi: 10.1111/bjh.13619. Epub 2015 Jul 29. No abstract available.

PMID:
26223361
33.

Morbidity associated with operative management of bladder stones in spinal cord-injured patients.

Eyre KS, Eyre DW, Reynard JM.

Spinal Cord. 2015 Nov;53(11):795-9. doi: 10.1038/sc.2015.36. Epub 2015 Mar 24.

PMID:
25800694
34.

Emergence and spread of predominantly community-onset Clostridium difficile PCR ribotype 244 infection in Australia, 2010 to 2012.

Eyre DW, Tracey L, Elliott B, Slimings C, Huntington PG, Stuart RL, Korman TM, Kotsiou G, McCann R, Griffiths D, Fawley WN, Armstrong P, Dingle KE, Walker AS, Peto TE, Crook DW, Wilcox MH, Riley TV.

Euro Surveill. 2015 Mar 12;20(10):21059.

35.

Diverse sources of C. difficile infection.

Eyre DW, Wilcox MH, Walker AS.

N Engl J Med. 2014 Jan 9;370(2):183-4. doi: 10.1056/NEJMc1313601. No abstract available.

PMID:
24401066
36.

Evolutionary history of the Clostridium difficile pathogenicity locus.

Dingle KE, Elliott B, Robinson E, Griffiths D, Eyre DW, Stoesser N, Vaughan A, Golubchik T, Fawley WN, Wilcox MH, Peto TE, Walker AS, Riley TV, Crook DW, Didelot X.

Genome Biol Evol. 2014 Jan;6(1):36-52. doi: 10.1093/gbe/evt204.

37.

Asymptomatic Clostridium difficile colonisation and onward transmission.

Eyre DW, Griffiths D, Vaughan A, Golubchik T, Acharya M, O'Connor L, Crook DW, Walker AS, Peto TE.

PLoS One. 2013 Nov 12;8(11):e78445. doi: 10.1371/journal.pone.0078445. eCollection 2013.

38.

Whole-genome sequencing demonstrates that fidaxomicin is superior to vancomycin for preventing reinfection and relapse of infection with Clostridium difficile.

Eyre DW, Babakhani F, Griffiths D, Seddon J, Del Ojo Elias C, Gorbach SL, Peto TE, Crook DW, Walker AS.

J Infect Dis. 2014 May 1;209(9):1446-51. doi: 10.1093/infdis/jit598. Epub 2013 Nov 11.

39.

Clostridium difficile surveillance: harnessing new technologies to control transmission.

Eyre DW, Walker AS.

Expert Rev Anti Infect Ther. 2013 Nov;11(11):1193-205. doi: 10.1586/14787210.2013.845987. Review.

PMID:
24151834
40.

Comparison of multilocus variable-number tandem-repeat analysis and whole-genome sequencing for investigation of Clostridium difficile transmission.

Eyre DW, Fawley WN, Best EL, Griffiths D, Stoesser NE, Crook DW, Peto TE, Walker AS, Wilcox MH.

J Clin Microbiol. 2013 Dec;51(12):4141-9. doi: 10.1128/JCM.01095-13. Epub 2013 Oct 9.

41.

Diverse sources of C. difficile infection identified on whole-genome sequencing.

Eyre DW, Cule ML, Wilson DJ, Griffiths D, Vaughan A, O'Connor L, Ip CLC, Golubchik T, Batty EM, Finney JM, Wyllie DH, Didelot X, Piazza P, Bowden R, Dingle KE, Harding RM, Crook DW, Wilcox MH, Peto TEA, Walker AS.

N Engl J Med. 2013 Sep 26;369(13):1195-205. doi: 10.1056/NEJMoa1216064.

42.

Predicting antimicrobial susceptibilities for Escherichia coli and Klebsiella pneumoniae isolates using whole genomic sequence data.

Stoesser N, Batty EM, Eyre DW, Morgan M, Wyllie DH, Del Ojo Elias C, Johnson JR, Walker AS, Peto TE, Crook DW.

J Antimicrob Chemother. 2013 Oct;68(10):2234-44. doi: 10.1093/jac/dkt180. Epub 2013 May 30.

43.

Short-term genome stability of serial Clostridium difficile ribotype 027 isolates in an experimental gut model and recurrent human disease.

Eyre DW, Walker AS, Freeman J, Baines SD, Fawley WN, Chilton CH, Griffiths D, Vaughan A, Crook DW, Peto TE, Wilcox MH.

PLoS One. 2013 May 15;8(5):e63540. doi: 10.1371/journal.pone.0063540. Print 2013.

44.

Detection of mixed infection from bacterial whole genome sequence data allows assessment of its role in Clostridium difficile transmission.

Eyre DW, Cule ML, Griffiths D, Crook DW, Peto TE, Walker AS, Wilson DJ.

PLoS Comput Biol. 2013;9(5):e1003059. doi: 10.1371/journal.pcbi.1003059. Epub 2013 May 2.

45.

Reply to Walk et al.

Walker AS, Eyre DW, Crook DW, Peto TE, Wilcox MH.

Clin Infect Dis. 2013 Aug;57(4):626-7. doi: 10.1093/cid/cit312. Epub 2013 May 8. No abstract available.

PMID:
23658434
46.

Relationship between bacterial strain type, host biomarkers, and mortality in Clostridium difficile infection.

Walker AS, Eyre DW, Wyllie DH, Dingle KE, Griffiths D, Shine B, Oakley S, O'Connor L, Finney J, Vaughan A, Crook DW, Wilcox MH, Peto TE; Infections in Oxfordshire Research Database.

Clin Infect Dis. 2013 Jun;56(11):1589-600. doi: 10.1093/cid/cit127. Epub 2013 Mar 5.

47.

Risk factors for Clostridium difficile acquisition in infants: importance of study design.

Stoesser NE, Martin J, Mawer D, Eyre DW, Walker AS, Peto TE, Crook DW, Wilcox MH.

Clin Infect Dis. 2013 Jun;56(11):1680-1. doi: 10.1093/cid/cit089. Epub 2013 Feb 26. No abstract available.

PMID:
23442761
48.

Regarding "Clostridium difficile ribotype does not predict severe infection".

Walker AS, Eyre DW, Crook DW, Wilcox MH, Peto TE.

Clin Infect Dis. 2013 Jun;56(12):1845-6. doi: 10.1093/cid/cit098. Epub 2013 Feb 18. No abstract available.

49.

Microevolutionary analysis of Clostridium difficile genomes to investigate transmission.

Didelot X, Eyre DW, Cule M, Ip CL, Ansari MA, Griffiths D, Vaughan A, O'Connor L, Golubchik T, Batty EM, Piazza P, Wilson DJ, Bowden R, Donnelly PJ, Dingle KE, Wilcox M, Walker AS, Crook DW, Peto TE, Harding RM.

Genome Biol. 2012 Dec 21;13(12):R118. doi: 10.1186/gb-2012-13-12-r118.

50.

Recombinational switching of the Clostridium difficile S-layer and a novel glycosylation gene cluster revealed by large-scale whole-genome sequencing.

Dingle KE, Didelot X, Ansari MA, Eyre DW, Vaughan A, Griffiths D, Ip CL, Batty EM, Golubchik T, Bowden R, Jolley KA, Hood DW, Fawley WN, Walker AS, Peto TE, Wilcox MH, Crook DW.

J Infect Dis. 2013 Feb 15;207(4):675-86. doi: 10.1093/infdis/jis734. Epub 2012 Nov 29.

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