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Items: 44

1.

A novel humanized mouse model with significant improvement of class-switched, antigen-specific antibody production.

Yu H, Borsotti C, Schickel JN, Zhu S, Strowig T, Eynon EE, Frleta D, Gurer C, Murphy AJ, Yancopoulos GD, Meffre E, Manz MG, Flavell RA.

Blood. 2017 Feb 23;129(8):959-969. doi: 10.1182/blood-2016-04-709584. Epub 2017 Jan 11.

2.

Microenvironment-dependent growth of preneoplastic and malignant plasma cells in humanized mice.

Das R, Strowig T, Verma R, Koduru S, Hafemann A, Hopf S, Kocoglu MH, Borsotti C, Zhang L, Branagan A, Eynon E, Manz MG, Flavell RA, Dhodapkar MV.

Nat Med. 2016 Nov;22(11):1351-1357. doi: 10.1038/nm.4202. Epub 2016 Oct 10.

3.

AMCase is a crucial regulator of type 2 immune responses to inhaled house dust mites.

Kim LK, Morita R, Kobayashi Y, Eisenbarth SC, Lee CG, Elias J, Eynon EE, Flavell RA.

Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):E2891-9. doi: 10.1073/pnas.1507393112. Epub 2015 May 18.

4.

Human hemato-lymphoid system mice: current use and future potential for medicine.

Rongvaux A, Takizawa H, Strowig T, Willinger T, Eynon EE, Flavell RA, Manz MG.

Annu Rev Immunol. 2013;31:635-674. doi: 10.1146/annurev-immunol-032712-095921. Epub 2013 Jan 16. Review.

5.

Efficient differentiation and function of human macrophages in humanized CSF-1 mice.

Rathinam C, Poueymirou WT, Rojas J, Murphy AJ, Valenzuela DM, Yancopoulos GD, Rongvaux A, Eynon EE, Manz MG, Flavell RA.

Blood. 2011 Sep 15;118(11):3119-28. doi: 10.1182/blood-2010-12-326926. Epub 2011 Jul 25.

6.

Transgenic expression of human signal regulatory protein alpha in Rag2-/-gamma(c)-/- mice improves engraftment of human hematopoietic cells in humanized mice.

Strowig T, Rongvaux A, Rathinam C, Takizawa H, Borsotti C, Philbrick W, Eynon EE, Manz MG, Flavell RA.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13218-23. doi: 10.1073/pnas.1109769108. Epub 2011 Jul 25.

7.

In vivo diabetogenic action of CD4+ T lymphocytes requires Fas expression and is independent of IL-1 and IL-18.

Wen L, Green EA, Stratmann T, Panosa A, Gomis R, Eynon EE, Flavell RA, Mezquita JA, Mora C.

Eur J Immunol. 2011 May;41(5):1344-51. doi: 10.1002/eji.201041216. Epub 2011 Apr 13.

8.

Human thrombopoietin knockin mice efficiently support human hematopoiesis in vivo.

Rongvaux A, Willinger T, Takizawa H, Rathinam C, Auerbach W, Murphy AJ, Valenzuela DM, Yancopoulos GD, Eynon EE, Stevens S, Manz MG, Flavell RA.

Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2378-83. doi: 10.1073/pnas.1019524108. Epub 2011 Jan 24.

9.

Human IL-3/GM-CSF knock-in mice support human alveolar macrophage development and human immune responses in the lung.

Willinger T, Rongvaux A, Takizawa H, Yancopoulos GD, Valenzuela DM, Murphy AJ, Auerbach W, Eynon EE, Stevens S, Manz MG, Flavell RA.

Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2390-5. doi: 10.1073/pnas.1019682108. Epub 2011 Jan 24.

10.

A mouse model for the human pathogen Salmonella typhi.

Song J, Willinger T, Rongvaux A, Eynon EE, Stevens S, Manz MG, Flavell RA, Galán JE.

Cell Host Microbe. 2010 Oct 21;8(4):369-76. doi: 10.1016/j.chom.2010.09.003.

11.

The transcription cofactor Hopx is required for regulatory T cell function in dendritic cell-mediated peripheral T cell unresponsiveness.

Hawiger D, Wan YY, Eynon EE, Flavell RA.

Nat Immunol. 2010 Oct;11(10):962-8. doi: 10.1038/ni.1929. Epub 2010 Aug 29.

12.

Regulating human Th17 cells via differential expression of IL-1 receptor.

Lee WW, Kang SW, Choi J, Lee SH, Shah K, Eynon EE, Flavell RA, Kang I.

Blood. 2010 Jan 21;115(3):530-40. doi: 10.1182/blood-2009-08-236521. Epub 2009 Nov 12.

13.

Humanized mice for modeling human infectious disease: challenges, progress, and outlook.

Legrand N, Ploss A, Balling R, Becker PD, Borsotti C, Brezillon N, Debarry J, de Jong Y, Deng H, Di Santo JP, Eisenbarth S, Eynon E, Flavell RA, Guzman CA, Huntington ND, Kremsdorf D, Manns MP, Manz MG, Mention JJ, Ott M, Rathinam C, Rice CM, Rongvaux A, Stevens S, Spits H, Strick-Marchand H, Takizawa H, van Lent AU, Wang C, Weijer K, Willinger T, Ziegler P.

Cell Host Microbe. 2009 Jul 23;6(1):5-9. doi: 10.1016/j.chom.2009.06.006. Review.

14.

Amino acid polymorphisms altering the glycosylation of IL-2 do not protect from type 1 diabetes in the NOD mouse.

Kamanaka M, Rainbow D, Schuster-Gossler K, Eynon EE, Chervonsky AV, Wicker LS, Flavell RA.

Proc Natl Acad Sci U S A. 2009 Jul 7;106(27):11236-40. doi: 10.1073/pnas.0904780106. Epub 2009 Jun 22.

15.

IL9 leads to airway inflammation by inducing IL13 expression in airway epithelial cells.

Temann UA, Laouar Y, Eynon EE, Homer R, Flavell RA.

Int Immunol. 2007 Jan;19(1):1-10. Epub 2006 Nov 13.

PMID:
17101709
16.

FAT10/diubiquitin-like protein-deficient mice exhibit minimal phenotypic differences.

Canaan A, Yu X, Booth CJ, Lian J, Lazar I, Gamfi SL, Castille K, Kohya N, Nakayama Y, Liu YC, Eynon E, Flavell R, Weissman SM.

Mol Cell Biol. 2006 Jul;26(13):5180-9.

17.

Gene regulation and function: its rocking science.

Dong C, Sanjabi S, Eynon E.

Immunity. 2005 Dec;23(6):557-60. No abstract available. Erratum in: Immunity. 2006 Jan;24(1):119.

18.

Sugar-coated regulation of T cells.

Eynon EE, Zenewicz LA, Flavell RA.

Cell. 2005 Jul 15;122(1):2-4. Review.

19.

Intracellular debugging.

Kobayashi KS, Eynon EE, Flavell RA.

Nat Immunol. 2003 Jul;4(7):652-4. No abstract available.

PMID:
12830145
20.

A lupus-like syndrome develops in mice lacking the Ro 60-kDa protein, a major lupus autoantigen.

Xue D, Shi H, Smith JD, Chen X, Noe DA, Cedervall T, Yang DD, Eynon E, Brash DE, Kashgarian M, Flavell RA, Wolin SL.

Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7503-8. Epub 2003 Jun 3.

21.
22.

Walking through the forest of transgenic models of human disease.

Eynon EE, Flavell RA.

Immunol Rev. 1999 Jun;169:5-10. Review.

PMID:
10450503
23.

Distinct effects of Jak3 signaling on alphabeta and gammadelta thymocyte development.

Eynon EE, Livák F, Kuida K, Schatz DG, Flavell RA.

J Immunol. 1999 Feb 1;162(3):1448-59.

24.
26.

Disruption of cytokine signaling in lymphoid development: unique contributions of the common cytokine gamma chain and the Jak3 kinase.

Eynon EE, Kuida K, Flavell RA.

J Interferon Cytokine Res. 1996 Sep;16(9):677-84. Review. No abstract available.

PMID:
8887051
27.

Activation and re-activation potential of T cells responding to staphylococcal enterotoxin B.

Hamel ME, Eynon EE, Savelkoul HF, van Oudenaren A, Kruisbeek AM.

Int Immunol. 1995 Jul;7(7):1065-77.

PMID:
8527404
28.
29.

Parameters of tolerance induction by antigen targeted to B lymphocytes.

Eynon EE, Parker DC.

J Immunol. 1993 Sep 15;151(6):2958-64.

PMID:
8376763
30.

Predictability of alloreactivity among unrelated individuals.

Awdeh ZL, Alper CA, Fici D, Eynon E, Bishara A, Yunis EJ.

Tissue Antigens. 1992 Feb;39(2):51-7.

PMID:
1574798
31.
32.

Antigen presentation in acquired immunological tolerance.

Parker DC, Eynon EE.

FASEB J. 1991 Oct;5(13):2777-84. Review.

PMID:
1916102
33.

Do small B cells induce tolerance?

Eynon EE, Parker DC.

Transplant Proc. 1991 Feb;23(1 Pt 1):729-30. No abstract available.

PMID:
1990666
34.

Demonstration of the antiviral role of natural killer cells in vivo with a natural killer cell-specific monoclonal antibody (NK 1.1).

Welsh RM, Dundon PL, Eynon EE, Brubaker JO, Koo GC, O'Donnell CL.

Nat Immun Cell Growth Regul. 1990;9(2):112-20.

PMID:
2352539
35.

Identification of HLA-B44 subtypes associated with extended MHC haplotypes.

Kruskall MS, Eynon EE, Awdeh Z, Alper CA, Yunis EJ.

Immunogenetics. 1987;26(4-5):216-9.

PMID:
3653939
36.

Characterization of HLA-Bw73 by serology and one-dimensional isoelectric focusing patterns.

Eynon EE, Yang SY, Cronin CR, Alosco SM, Alper CA, Yunis EJ.

Hum Immunol. 1986 Aug;16(4):356-63.

PMID:
2428782
37.

Differential expression of T cell differentiation antigens and major histocompatibility antigens on activated T cells during the cell cycle.

Matsui Y, Shapiro HM, Sheehy MJ, Christenson L, Staunton DE, Eynon EE, Yunis EJ.

Eur J Immunol. 1986 Mar;16(3):248-51.

PMID:
3082649
38.

Unrelated individuals matched for MHC extended haplotypes and HLA-identical siblings show comparable responses in mixed lymphocyte culture.

Awdeh ZL, Alper CA, Eynon E, Alosco SM, Stein R, Yunis EJ.

Lancet. 1985 Oct 19;2(8460):853-6.

PMID:
2864576
39.

Mechanism of the pressor response to tetradecapeptide renin substrate in the rat.

Sybertz EJ, Ahn HS, Baum T, Eynon E, Nelson S, Washington P, Czarniecki M.

Clin Exp Hypertens A. 1984;6(12):2143-59.

PMID:
6099783
40.

Antihypertensive activity of SCH 31846, a non-sulfhydryl angiotensin-converting enzyme inhibitor.

Baum T, Sybertz EJ, Watkins RW, Ahn HS, Nelson S, Eynon E, Vander Vliet G, Pula KK, Sabin C, Desiderio DM, Becker FT, Vemulapalli S.

J Cardiovasc Pharmacol. 1983 Jul-Aug;5(4):655-67.

PMID:
6193365
41.

Angiotensin-converting enzyme inhibitory activity of SCH 31846, a new non-sulfhydryl inhibitor.

Sybertz EJ, Baum T, Ahn HS, Nelson S, Eynon E, Desiderio DM, Pula K, Becker F, Sabin C, Moran R, Vander Vliet G, Kastner B, Smith E.

J Cardiovasc Pharmacol. 1983 Jul-Aug;5(4):643-54.

PMID:
6193364
42.

Studies on the interactions of acetyl glycerol ether phosphoryl choline with the sympathetic nervous system in rats.

Sybertz EJ, Sabin C, Baum T, Eynon E, Nelson S, Moran R.

J Pharmacol Exp Ther. 1982 Dec;223(3):594-8. No abstract available.

PMID:
7143227
43.

Studies on the mechanism of the acute antihypertensive and vasodilator actions of several beta-adrenoceptor antagonists.

Sybertz EJ, Baum T, Pula KK, Nelson S, Eynon E, Sabin C.

J Cardiovasc Pharmacol. 1982 Sep-Oct;4(5):749-58.

PMID:
6182405
44.

Antihypertensive and hemodynamic actions of SCH 19927, the R,R-isomer and labetalol.

Baum T, Watkins RW, Sybertz EJ, Vemulapalli S, Pula KK, Eynon E, Nelson S, Vliet GV, Glennon J, Moran RM.

J Pharmacol Exp Ther. 1981 Aug;218(2):444-52.

PMID:
7252843

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