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Items: 29


Contribution of σ70 and σN Factors to Expression of Class II pilE in Neisseria meningitidis.

Lobanovska M, Tang CM, Exley RM.

J Bacteriol. 2019 Sep 20;201(20). pii: e00170-19. doi: 10.1128/JB.00170-19. Print 2019 Oct 15.


Structure-based design of chimeric antigens for multivalent protein vaccines.

Hollingshead S, Jongerius I, Exley RM, Johnson S, Lea SM, Tang CM.

Nat Commun. 2018 Mar 13;9(1):1051. doi: 10.1038/s41467-018-03146-7.


Neisseria cinerea isolates can adhere to human epithelial cells by type IV pilus-independent mechanisms.

Wörmann ME, Horien CL, Johnson E, Liu G, Aho E, Tang CM, Exley RM.

Microbiology. 2016 Mar;162(3):487-502. doi: 10.1099/mic.0.000248. Epub 2016 Jan 26.


Sugar coating: bacterial protein glycosylation and host-microbe interactions.

Tan FY, Tang CM, Exley RM.

Trends Biochem Sci. 2015 Jul;40(7):342-50. doi: 10.1016/j.tibs.2015.03.016. Epub 2015 Apr 30. Review.


Non-pathogenic Neisseria: members of an abundant, multi-habitat, diverse genus.

Liu G, Tang CM, Exley RM.

Microbiology. 2015 Jul;161(7):1297-1312. doi: 10.1099/mic.0.000086. Epub 2015 Mar 26. Review.


Characterization of a novel antisense RNA in the major pilin locus of Neisseria meningitidis influencing antigenic variation.

Tan FY, Wörmann ME, Loh E, Tang CM, Exley RM.

J Bacteriol. 2015 May;197(10):1757-68. doi: 10.1128/JB.00082-15. Epub 2015 Mar 9.


Competition between antagonistic complement factors for a single protein on N. meningitidis rules disease susceptibility.

Caesar JJ, Lavender H, Ward PN, Exley RM, Eaton J, Chittock E, Malik TH, Goiecoechea De Jorge E, Pickering MC, Tang CM, Lea SM.

Elife. 2014 Dec 23;3. doi: 10.7554/eLife.04008.


Sequence, distribution and chromosomal context of class I and class II pilin genes of Neisseria meningitidis identified in whole genome sequences.

Wörmann ME, Horien CL, Bennett JS, Jolley KA, Maiden MC, Tang CM, Aho EL, Exley RM.

BMC Genomics. 2014 Apr 1;15:253. doi: 10.1186/1471-2164-15-253.


Distinct binding and immunogenic properties of the gonococcal homologue of meningococcal factor h binding protein.

Jongerius I, Lavender H, Tan L, Ruivo N, Exley RM, Caesar JJ, Lea SM, Johnson S, Tang CM.

PLoS Pathog. 2013;9(8):e1003528. doi: 10.1371/journal.ppat.1003528. Epub 2013 Aug 1.


Design and evaluation of meningococcal vaccines through structure-based modification of host and pathogen molecules.

Johnson S, Tan L, van der Veen S, Caesar J, Goicoechea De Jorge E, Harding RJ, Bai X, Exley RM, Ward PN, Ruivo N, Trivedi K, Cumber E, Jones R, Newham L, Staunton D, Ufret-Vincenty R, Borrow R, Pickering MC, Lea SM, Tang CM.

PLoS Pathog. 2012;8(10):e1002981. doi: 10.1371/journal.ppat.1002981. Epub 2012 Oct 25. Erratum in: PLoS Pathog. 2013 Jan;9(1). doi: 10.1371/annotation/3e7e6415-fb12-4a87-89e6-f87d2e800ba8.


Galectin-3 binds Neisseria meningitidis and increases interaction with phagocytic cells.

Quattroni P, Li Y, Lucchesi D, Lucas S, Hood DW, Herrmann M, Gabius HJ, Tang CM, Exley RM.

Cell Microbiol. 2012 Nov;14(11):1657-75. doi: 10.1111/j.1462-5822.2012.01838.x. Epub 2012 Aug 12.


New insights into pathogen recognition.

Quattroni P, Exley RM, Tang CM.

Expert Rev Anti Infect Ther. 2011 Aug;9(8):577-9. doi: 10.1586/eri.11.73.


Mechanisms of meningococcal colonisation.

Trivedi K, Tang CM, Exley RM.

Trends Microbiol. 2011 Sep;19(9):456-63. doi: 10.1016/j.tim.2011.06.006. Epub 2011 Aug 2. Review.


Glutamate utilization promotes meningococcal survival in vivo through avoidance of the neutrophil oxidative burst.

Talà A, Monaco C, Nagorska K, Exley RM, Corbett A, Zychlinsky A, Alifano P, Tang CM.

Mol Microbiol. 2011 Sep;81(5):1330-42. doi: 10.1111/j.1365-2958.2011.07766.x. Epub 2011 Jul 20.


Characterization of Neisseria meningitidis isolates that do not express the virulence factor and vaccine antigen factor H binding protein.

Lucidarme J, Tan L, Exley RM, Findlow J, Borrow R, Tang CM.

Clin Vaccine Immunol. 2011 Jun;18(6):1002-14. doi: 10.1128/CVI.00055-11. Epub 2011 Apr 20.


Transcellular passage of Neisseria meningitidis across a polarized respiratory epithelium.

Sutherland TC, Quattroni P, Exley RM, Tang CM.

Infect Immun. 2010 Sep;78(9):3832-47. doi: 10.1128/IAI.01377-09. Epub 2010 Jun 28.


Sequence conservation of pilus subunits in Neisseria meningitidis.

Cehovin A, Winterbotham M, Lucidarme J, Borrow R, Tang CM, Exley RM, Pelicic V.

Vaccine. 2010 Jul 5;28(30):4817-26. doi: 10.1016/j.vaccine.2010.04.065. Epub 2010 May 8.


Mechanisms of avoidance of host immunity by Neisseria meningitidis and its effect on vaccine development.

Lo H, Tang CM, Exley RM.

Lancet Infect Dis. 2009 Jul;9(7):418-27. doi: 10.1016/S1473-3099(09)70132-X. Review.


Identification of meningococcal genes necessary for colonization of human upper airway tissue.

Exley RM, Sim R, Goodwin L, Winterbotham M, Schneider MC, Read RC, Tang CM.

Infect Immun. 2009 Jan;77(1):45-51. doi: 10.1128/IAI.00968-08. Epub 2008 Oct 20.


A generic mechanism in Neisseria meningitidis for enhanced resistance against bactericidal antibodies.

Uria MJ, Zhang Q, Li Y, Chan A, Exley RM, Gollan B, Chan H, Feavers I, Yarwood A, Abad R, Borrow R, Fleck RA, Mulloy B, Vazquez JA, Tang CM.

J Exp Med. 2008 Jun 9;205(6):1423-34. doi: 10.1084/jem.20072577. Epub 2008 May 26.


Effect of host lactate on gonococci and meningococci: new concepts on the role of metabolites in pathogenicity.

Smith H, Tang CM, Exley RM.

Infect Immun. 2007 Sep;75(9):4190-8. Epub 2007 Jun 11. Review. No abstract available.


Interactions between Neisseria meningitidis and the complement system.

Schneider MC, Exley RM, Ram S, Sim RB, Tang CM.

Trends Microbiol. 2007 May;15(5):233-40. Epub 2007 Mar 29. Review.


Lactate acquisition promotes successful colonization of the murine genital tract by Neisseria gonorrhoeae.

Exley RM, Wu H, Shaw J, Schneider MC, Smith H, Jerse AE, Tang CM.

Infect Immun. 2007 Mar;75(3):1318-24. Epub 2006 Dec 11.


Functional significance of factor H binding to Neisseria meningitidis.

Schneider MC, Exley RM, Chan H, Feavers I, Kang YH, Sim RB, Tang CM.

J Immunol. 2006 Jun 15;176(12):7566-75.


Neisseria meningitidis lactate permease is required for nasopharyngeal colonization.

Exley RM, Goodwin L, Mowe E, Shaw J, Smith H, Read RC, Tang CM.

Infect Immun. 2005 Sep;73(9):5762-6.


Identification of novel antigens that protect against systemic meningococcal infection.

Sun Y, Li Y, Exley RM, Winterbotham M, Ison C, Smith H, Tang CM.

Vaccine. 2005 Jul 14;23(32):4136-41. Epub 2005 Apr 14.


Available carbon source influences the resistance of Neisseria meningitidis against complement.

Exley RM, Shaw J, Mowe E, Sun YH, West NP, Williamson M, Botto M, Smith H, Tang CM.

J Exp Med. 2005 May 16;201(10):1637-45.


Optimization of virulence functions through glucosylation of Shigella LPS.

West NP, Sansonetti P, Mounier J, Exley RM, Parsot C, Guadagnini S, Prévost MC, Prochnicka-Chalufour A, Delepierre M, Tanguy M, Tang CM.

Science. 2005 Feb 25;307(5713):1313-7.


Different in vivo localization of the Escherichia coli proteins CspD and CspA.

Giangrossi M, Exley RM, Le Hegarat F, Pon CL.

FEMS Microbiol Lett. 2001 Aug 21;202(2):171-6. Erratum in: FEMS Microbiol Lett 2002 Mar 5;208(2):305.

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