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Items: 1 to 50 of 222

1.

From Dense Core to Halo: Amperometric Measurements and Dynamic Models Reveal a Mechanism for How Zinc Alters Neurotransmitter Release.

Ren L, Oleinick A, Svir I, Amatore C, Ewing AG.

Angew Chem Int Ed Engl. 2019 Dec 11. doi: 10.1002/anie.201913184. [Epub ahead of print]

PMID:
31825147
2.

Spatial Lipidomics Reveals Region and Long Chain Base Specific Accumulations of Monosialogangliosides in Amyloid Plaques in Familial Alzheimer's Disease Mice (5xFAD) Brain.

Kaya I, Jennische E, Dunevall J, Lange S, Ewing AG, Malmberg P, Baykal AT, Fletcher JS.

ACS Chem Neurosci. 2020 Jan 2;11(1):14-24. doi: 10.1021/acschemneuro.9b00532. Epub 2019 Dec 12.

PMID:
31774647
3.

Plasticity in exocytosis revealed through the effects of repetitive stimuli affect the content of nanometer vesicles and the fraction of transmitter released.

Gu C, Larsson A, Ewing AG.

Proc Natl Acad Sci U S A. 2019 Oct 22;116(43):21409-21415. doi: 10.1073/pnas.1910859116. Epub 2019 Sep 30.

PMID:
31570594
4.

Extracellular ATP Regulates the Vesicular Pore Opening in Chromaffin Cells and Increases the Fraction Released During Individual Exocytosis Events.

Majdi S, Larsson A, Najafinobar N, Borges R, Ewing AG.

ACS Chem Neurosci. 2019 May 15;10(5):2459-2466. doi: 10.1021/acschemneuro.8b00722. Epub 2019 Apr 1.

PMID:
30892011
5.

Dopamine Release Dynamics in the Tuberoinfundibular Dopamine System.

Stagkourakis S, Dunevall J, Taleat Z, Ewing AG, Broberger C.

J Neurosci. 2019 May 22;39(21):4009-4022. doi: 10.1523/JNEUROSCI.2339-18.2019. Epub 2019 Feb 19.

6.

Anticancer Drug Tamoxifen Affects Catecholamine Transmitter Release and Storage from Single Cells.

Taleat Z, Larsson A, Ewing AG.

ACS Chem Neurosci. 2019 Apr 17;10(4):2060-2069. doi: 10.1021/acschemneuro.8b00714. Epub 2019 Feb 26.

PMID:
30763068
7.

Altered Lipid Composition of Secretory Cells Following Exposure to Zinc Can Be Correlated to Changes in Exocytosis.

Ren L, Dowlatshahi Pour M, Malmberg P, Ewing AG.

Chemistry. 2019 Apr 11;25(21):5406-5411. doi: 10.1002/chem.201900010. Epub 2019 Mar 13.

PMID:
30762272
8.

Combined Amperometry and Electrochemical Cytometry Reveal Differential Effects of Cocaine and Methylphenidate on Exocytosis and the Fraction of Chemical Release.

Zhu W, Gu C, Dunevall J, Ren L, Zhou X, Ewing AG.

Angew Chem Int Ed Engl. 2019 Mar 22;58(13):4238-4242. doi: 10.1002/anie.201813717. Epub 2019 Feb 18.

9.

Chemical Analysis of Single Cells.

Oomen PE, Aref MA, Kaya I, Phan NTN, Ewing AG.

Anal Chem. 2019 Jan 2;91(1):588-621. doi: 10.1021/acs.analchem.8b04732. Epub 2018 Dec 12. No abstract available.

PMID:
30362708
10.

On-Tissue Chemical Derivatization of Catecholamines Using 4-( N-Methyl)pyridinium Boronic Acid for ToF-SIMS and LDI-ToF Mass Spectrometry Imaging.

Kaya I, Brülls SM, Dunevall J, Jennische E, Lange S, Mårtensson J, Ewing AG, Malmberg P, Fletcher JS.

Anal Chem. 2018 Nov 20;90(22):13580-13590. doi: 10.1021/acs.analchem.8b03746. Epub 2018 Nov 5.

PMID:
30346141
11.

Relative quantification of deuterated omega-3 and -6 fatty acids and their lipid turnover in PC12 cell membranes using TOF-SIMS.

Philipsen MH, Sämfors S, Malmberg P, Ewing AG.

J Lipid Res. 2018 Nov;59(11):2098-2107. doi: 10.1194/jlr.M087734. Epub 2018 Sep 11.

12.

Electrochemical quantification of transmitter concentration in single nanoscale vesicles isolated from PC12 cells.

Li X, Dunevall J, Ewing AG.

Faraday Discuss. 2018 Oct 1;210(0):353-364. doi: 10.1039/c8fd00020d.

PMID:
29989629
13.

Mass Spectrometry Imaging Suggests That Cisplatin Affects Exocytotic Release by Alteration of Cell Membrane Lipids.

Mohammadi AS, Li X, Ewing AG.

Anal Chem. 2018 Jul 17;90(14):8509-8516. doi: 10.1021/acs.analchem.8b01395. Epub 2018 Jul 6.

PMID:
29912552
14.

Benefits of NaCl addition for time-of-flight secondary ion mass spectrometry analysis including the discrimination of diacylglyceride and triacylglyceride ions.

Sämfors S, Ewing AG, Fletcher JS.

Rapid Commun Mass Spectrom. 2018 Sep 15;32(17):1473-1480. doi: 10.1002/rcm.8181.

15.

Nanopore Opening at Flat and Nanotip Conical Electrodes during Vesicle Impact Electrochemical Cytometry.

Li X, Ren L, Dunevall J, Ye D, White HS, Edwards MA, Ewing AG.

ACS Nano. 2018 Mar 27;12(3):3010-3019. doi: 10.1021/acsnano.8b00781. Epub 2018 Mar 16.

PMID:
29513514
16.

Mass Spectrometry Imaging Shows Cocaine and Methylphenidate Have Opposite Effects on Major Lipids in Drosophila Brain.

Philipsen MH, Phan NTN, Fletcher JS, Malmberg P, Ewing AG.

ACS Chem Neurosci. 2018 Jun 20;9(6):1462-1468. doi: 10.1021/acschemneuro.8b00046. Epub 2018 Mar 20.

PMID:
29508991
17.

Electrochemical Investigation of the Interaction between Catecholamines and ATP.

Taleat Z, Estévez-Herrera J, Machado JD, Dunevall J, Ewing AG, Borges R.

Anal Chem. 2018 Feb 6;90(3):1601-1607. doi: 10.1021/acs.analchem.7b02494. Epub 2018 Jan 22.

PMID:
29286231
18.

DMSO Chemically Alters Cell Membranes to Slow Exocytosis and Increase the Fraction of Partial Transmitter Released.

Majdi S, Najafinobar N, Dunevall J, Lovric J, Ewing AG.

Chembiochem. 2017 Oct 5;18(19):1898-1902. doi: 10.1002/cbic.201700410. Epub 2017 Aug 21.

PMID:
28834067
19.

Mechanistic Aspects of Vesicle Opening during Analysis with Vesicle Impact Electrochemical Cytometry.

Li X, Dunevall J, Ren L, Ewing AG.

Anal Chem. 2017 Sep 5;89(17):9416-9423. doi: 10.1021/acs.analchem.7b02226. Epub 2017 Aug 22.

PMID:
28776974
20.

Single cell amperometry reveals curcuminoids modulate the release of neurotransmitters during exocytosis from PC12 cells.

Li X, Mohammadi AS, Ewing AG.

J Electroanal Chem (Lausanne). 2016 Nov 15;781:30-35. doi: 10.1016/j.jelechem.2016.10.025. Epub 2016 Oct 13.

21.

MS/MS analysis and imaging of lipids across Drosophila brain using secondary ion mass spectrometry.

Phan NTN, Munem M, Ewing AG, Fletcher JS.

Anal Bioanal Chem. 2017 Jun;409(16):3923-3932. doi: 10.1007/s00216-017-0336-4. Epub 2017 Apr 7.

22.

Zinc Regulates Chemical-Transmitter Storage in Nanometer Vesicles and Exocytosis Dynamics as Measured by Amperometry.

Ren L, Pour MD, Majdi S, Li X, Malmberg P, Ewing AG.

Angew Chem Int Ed Engl. 2017 Apr 24;56(18):4970-4975. doi: 10.1002/anie.201700095. Epub 2017 Mar 20.

23.

Nano Secondary Ion Mass Spectrometry Imaging of Dopamine Distribution Across Nanometer Vesicles.

Lovrić J, Dunevall J, Larsson A, Ren L, Andersson S, Meibom A, Malmberg P, Kurczy ME, Ewing AG.

ACS Nano. 2017 Apr 25;11(4):3446-3455. doi: 10.1021/acsnano.6b07233. Epub 2016 Dec 27.

PMID:
27997789
24.

Quantitative Chemical Measurements of Vesicular Transmitters with Electrochemical Cytometry.

Li X, Dunevall J, Ewing AG.

Acc Chem Res. 2016 Oct 18;49(10):2347-2354. Epub 2016 Sep 13.

PMID:
27622924
25.

On the mechanism of electrochemical vesicle cytometry: chromaffin cell vesicles and liposomes.

Lovrić J, Najafinobar N, Dunevall J, Majdi S, Svir I, Oleinick A, Amatore C, Ewing AG.

Faraday Discuss. 2016 Dec 12;193:65-79.

PMID:
27711871
26.

The evidence for open and closed exocytosis as the primary release mechanism.

Ren L, Mellander LJ, Keighron J, Cans AS, Kurczy ME, Svir I, Oleinick A, Amatore C, Ewing AG.

Q Rev Biophys. 2016 Jan;49:e12. Epub 2016 Jul 18.

PMID:
27659043
27.

Food-induced changes of lipids in rat neuronal tissue visualized by ToF-SIMS imaging.

Dowlatshahi Pour M, Jennische E, Lange S, Ewing AG, Malmberg P.

Sci Rep. 2016 Sep 6;6:32797. doi: 10.1038/srep32797.

28.

Intact lipid imaging of mouse brain samples: MALDI, nanoparticle-laser desorption ionization, and 40 keV argon cluster secondary ion mass spectrometry.

Mohammadi AS, Phan NT, Fletcher JS, Ewing AG.

Anal Bioanal Chem. 2016 Sep;408(24):6857-68. doi: 10.1007/s00216-016-9812-5. Epub 2016 Aug 22.

29.

Multimodal Imaging of Chemically Fixed Cells in Preparation for NanoSIMS.

Lovrić J, Malmberg P, Johansson BR, Fletcher JS, Ewing AG.

Anal Chem. 2016 Sep 6;88(17):8841-8. doi: 10.1021/acs.analchem.6b02408. Epub 2016 Aug 9.

PMID:
27462909
30.

Using Single-Cell Amperometry To Reveal How Cisplatin Treatment Modulates the Release of Catecholamine Transmitters during Exocytosis.

Li X, Dunevall J, Ewing AG.

Angew Chem Int Ed Engl. 2016 Jul 25;55(31):9041-4. doi: 10.1002/anie.201602977. Epub 2016 May 30.

PMID:
27239950
31.

Lithographic Microfabrication of a 16-Electrode Array on a Probe Tip for High Spatial Resolution Electrochemical Localization of Exocytosis.

Wigström J, Dunevall J, Najafinobar N, Lovrić J, Wang J, Ewing AG, Cans AS.

Anal Chem. 2016 Feb 16;88(4):2080-7. doi: 10.1021/acs.analchem.5b03316. Epub 2016 Jan 28.

PMID:
26771211
32.

Mass spectrometric profiling of lipids in intestinal tissue from rats fed cereals processed for medical conditions.

Dowlatshahi Pour M, Jennische E, Lange S, Ewing AG, Malmberg P.

Biointerphases. 2016 Jun 11;11(2):02A310. doi: 10.1116/1.4939599.

PMID:
26753787
33.

Laser Desorption Ionization Mass Spectrometry Imaging of Drosophila Brain Using Matrix Sublimation versus Modification with Nanoparticles.

Phan NT, Mohammadi AS, Dowlatshahi Pour M, Ewing AG.

Anal Chem. 2016 Feb 2;88(3):1734-41. doi: 10.1021/acs.analchem.5b03942. Epub 2016 Jan 12.

PMID:
26705612
34.

Electrochemical Measurements of Optogenetically Stimulated Quantal Amine Release from Single Nerve Cell Varicosities in Drosophila Larvae.

Majdi S, Berglund EC, Dunevall J, Oleinick AI, Amatore C, Krantz DE, Ewing AG.

Angew Chem Int Ed Engl. 2015 Nov 9;54(46):13609-12. doi: 10.1002/anie.201506743. Epub 2015 Sep 21.

35.

Quantitative measurement of transmitters in individual vesicles in the cytoplasm of single cells with nanotip electrodes.

Li X, Majdi S, Dunevall J, Fathali H, Ewing AG.

Angew Chem Int Ed Engl. 2015 Oct 5;54(41):11978-82. doi: 10.1002/anie.201504839. Epub 2015 Aug 12.

36.

ToF-SIMS imaging of lipids and lipid related compounds in Drosophila brain.

Phan NT, Fletcher JS, Sjövall P, Ewing AG.

Surf Interface Anal. 2014 Nov;46(Suppl 1):123-126.

37.

Analysis of liposome model systems by time-of-flight secondary ion mass spectrometry.

Lovrić J, Keighron JD, Angerer TB, Li X, Malmberg P, Fletcher JS, Ewing AG.

Surf Interface Anal. 2014 Nov;46(Suppl 1):74-78.

38.

Lipid structural effects of oral administration of methylphenidate in Drosophila brain by secondary ion mass spectrometry imaging.

Phan NT, Fletcher JS, Ewing AG.

Anal Chem. 2015 Apr 21;87(8):4063-71. doi: 10.1021/acs.analchem.5b00555. Epub 2015 Apr 13.

PMID:
25856152
39.

Characterizing the catecholamine content of single mammalian vesicles by collision-adsorption events at an electrode.

Dunevall J, Fathali H, Najafinobar N, Lovric J, Wigström J, Cans AS, Ewing AG.

J Am Chem Soc. 2015 Apr 8;137(13):4344-6. doi: 10.1021/ja512972f. Epub 2015 Mar 31.

PMID:
25811247
40.

Selected recent in vivo studies on chemical measurements in invertebrates.

Majdi S, Ren L, Fathali H, Li X, Ewing AG.

Analyst. 2015 Jun 7;140(11):3676-86. doi: 10.1039/c4an02172j. Review.

PMID:
25646176
41.

Spatial neuroproteomics using imaging mass spectrometry.

Hanrieder J, Malmberg P, Ewing AG.

Biochim Biophys Acta. 2015 Jul;1854(7):718-31. doi: 10.1016/j.bbapap.2014.12.026. Epub 2015 Jan 9. Review.

PMID:
25582083
42.

Probing the lipid chemistry of neurotoxin-induced hippocampal lesions using multimodal imaging mass spectrometry.

Hanrieder J, Karlsson O, Brittebo E, Malmberg P, Ewing AG.

Surf Interface Anal. 2014 Nov;46(Suppl 1):375-378. doi: 10.1002/sia.5418. Epub 2014 Mar 28.

43.

Development of an organic lateral resolution test device for imaging mass spectrometry.

Passarelli MK, Wang J, Mohammadi AS, Trouillon R, Gilmore I, Ewing AG.

Anal Chem. 2014 Oct 7;86(19):9473-80. doi: 10.1021/ac501228x. Epub 2014 Sep 15.

44.

Spatial elucidation of spinal cord lipid- and metabolite- regulations in amyotrophic lateral sclerosis.

Hanrieder J, Ewing AG.

Sci Rep. 2014 Jun 12;4:5266. doi: 10.1038/srep05266.

45.

High resolution metabolite imaging in the hippocampus following neonatal exposure to the environmental toxin BMAA using ToF-SIMS.

Hanrieder J, Gerber L, Persson Sandelius Å, Brittebo EB, Ewing AG, Karlsson O.

ACS Chem Neurosci. 2014 Jul 16;5(7):568-75. doi: 10.1021/cn500039b. Epub 2014 May 9.

46.

Simultaneous study of subcellular exocytosis with individually addressable multiple microelectrodes.

Wang J, Ewing AG.

Analyst. 2014 Jul 7;139(13):3290-5. doi: 10.1039/c4an00058g.

PMID:
24740449
47.

Spatial resolution of single-cell exocytosis by microwell-based individually addressable thin film ultramicroelectrode arrays.

Wang J, Trouillon R, Dunevall J, Ewing AG.

Anal Chem. 2014 May 6;86(9):4515-20. doi: 10.1021/ac500443q. Epub 2014 Apr 23.

48.

Pituitary adenylate cyclase activating polypeptide modulates catecholamine storage and exocytosis in PC12 cells.

Dong Y, Ning G, Ewing AG, Heien ML.

PLoS One. 2014 Mar 6;9(3):e91132. doi: 10.1371/journal.pone.0091132. eCollection 2014.

49.

Two modes of exocytosis in an artificial cell.

Mellander LJ, Kurczy ME, Najafinobar N, Dunevall J, Ewing AG, Cans AS.

Sci Rep. 2014 Jan 24;4:3847. doi: 10.1038/srep03847.

50.

Actin controls the vesicular fraction of dopamine released during extended kiss and run exocytosis.

Trouillon R, Ewing AG.

ACS Chem Biol. 2014 Mar 21;9(3):812-20. doi: 10.1021/cb400665f. Epub 2014 Jan 21.

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