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Items: 46

1.

The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity.

Kitajima S, Yoshida A, Kohno S, Li F, Suzuki S, Nagatani N, Nishimoto Y, Sasaki N, Muranaka H, Wan Y, Thai TC, Okahashi N, Matsuda F, Shimizu H, Nishiuchi T, Suzuki Y, Tominaga K, Gotoh N, Suzuki M, Ewen ME, Barbie DA, Hirose O, Tanaka T, Takahashi C.

Oncogene. 2017 Sep 7;36(36):5145-5157. doi: 10.1038/onc.2017.124. Epub 2017 May 8.

PMID:
28481867
2.

Retinoblastoma protein and MyoD function together to effect the repression of Fra-1 and in turn cyclin D1 during terminal cell cycle arrest associated with myogenesis.

Rajabi HN, Takahashi C, Ewen ME.

J Biol Chem. 2014 Aug 22;289(34):23417-27. doi: 10.1074/jbc.M113.532572. Epub 2014 Jul 8.

3.

Cyclin D1 and C/EBPβ LAP1 operate in a common pathway to promote mammary epithelial cell differentiation.

Liu Q, Boudot A, Ni J, Hennessey T, Beauparlant SL, Rajabi HN, Zahnow C, Ewen ME.

Mol Cell Biol. 2014 Aug;34(16):3168-79. doi: 10.1128/MCB.00039-14. Epub 2014 Jun 9.

4.

CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3.

Chen J, Yao Y, Gong C, Yu F, Su S, Chen J, Liu B, Deng H, Wang F, Lin L, Yao H, Su F, Anderson KS, Liu Q, Ewen ME, Yao X, Song E.

Cancer Cell. 2011 Apr 12;19(4):541-55. doi: 10.1016/j.ccr.2011.02.006. Erratum in: Cancer Cell. 2011 Jun 14;19(6):814-6.

5.

Wild-type NRas and KRas perform distinct functions during transformation.

Fotiadou PP, Takahashi C, Rajabi HN, Ewen ME.

Mol Cell Biol. 2007 Oct;27(19):6742-55. Epub 2007 Jul 16.

6.

Genetic interaction between Rb and N-ras: differentiation control and metastasis.

Takahashi C, Ewen ME.

Cancer Res. 2006 Oct 1;66(19):9345-8. Review.

7.

Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor.

Takahashi C, Contreras B, Iwanaga T, Takegami Y, Bakker A, Bronson RT, Noda M, Loda M, Hunt JL, Ewen ME.

Nat Genet. 2006 Jan;38(1):118-23. Epub 2005 Dec 20.

PMID:
16369533
8.

Genetic interaction between Rb and K-ras in the control of differentiation and tumor suppression.

Takahashi C, Contreras B, Bronson RT, Loda M, Ewen ME.

Mol Cell Biol. 2004 Dec;24(23):10406-15.

9.

The activities of cyclin D1 that drive tumorigenesis.

Ewen ME, Lamb J.

Trends Mol Med. 2004 Apr;10(4):158-62.

PMID:
15059606
10.

Cyclin D1 and molecular chaperones: implications for tumorigenesis.

Lamb J, Ewen ME.

Cell Cycle. 2003 Nov-Dec;2(6):525-7. Review.

PMID:
14504466
11.

A mechanism of cyclin D1 action encoded in the patterns of gene expression in human cancer.

Lamb J, Ramaswamy S, Ford HL, Contreras B, Martinez RV, Kittrell FS, Zahnow CA, Patterson N, Golub TR, Ewen ME.

Cell. 2003 Aug 8;114(3):323-34.

12.

Rb and N-ras function together to control differentiation in the mouse.

Takahashi C, Bronson RT, Socolovsky M, Contreras B, Lee KY, Jacks T, Noda M, Kucherlapati R, Ewen ME.

Mol Cell Biol. 2003 Aug;23(15):5256-68.

13.

Regulation of the functional interaction between cyclin D1 and the estrogen receptor.

Lamb J, Ladha MH, McMahon C, Sutherland RL, Ewen ME.

Mol Cell Biol. 2000 Dec;20(23):8667-75.

15.

Where the cell cycle and histones meet.

Ewen ME.

Genes Dev. 2000 Sep 15;14(18):2265-70. Review. No abstract available.

16.

Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation.

Vairo G, Soos TJ, Upton TM, Zalvide J, DeCaprio JA, Ewen ME, Koff A, Adams JM.

Mol Cell Biol. 2000 Jul;20(13):4745-53.

17.

Relationship between Ras pathways and cell cycle control.

Ewen ME.

Prog Cell Cycle Res. 2000;4:1-17. Review.

PMID:
10740810
18.

The retinoblastoma protein is linked to the activation of Ras.

Lee KY, Ladha MH, McMahon C, Ewen ME.

Mol Cell Biol. 1999 Nov;19(11):7724-32.

19.

P/CAF associates with cyclin D1 and potentiates its activation of the estrogen receptor.

McMahon C, Suthiphongchai T, DiRenzo J, Ewen ME.

Proc Natl Acad Sci U S A. 1999 May 11;96(10):5382-7.

20.

Enforced CDK4 expression in a hematopoietic cell line confers resistance to the G1 arrest induced by ionizing radiation.

Reed MF, Liu VF, Ladha MH, Ando K, Griffin JD, Weaver DT, Ewen ME.

Oncogene. 1998 Dec 10;17(23):2961-71.

21.

Regulation of exit from quiescence by p27 and cyclin D1-CDK4.

Ladha MH, Lee KY, Upton TM, Reed MF, Ewen ME.

Mol Cell Biol. 1998 Nov;18(11):6605-15.

22.

Regulation of the cell cycle by the Rb tumor suppressor family.

Ewen ME.

Results Probl Cell Differ. 1998;22:149-79. Review. No abstract available.

PMID:
9670323
23.

p16INK4A participates in a G1 arrest checkpoint in response to DNA damage.

Shapiro GI, Edwards CD, Ewen ME, Rollins BJ.

Mol Cell Biol. 1998 Jan;18(1):378-87.

24.

Cyclin D1 stimulation of estrogen receptor transcriptional activity independent of cdk4.

Neuman E, Ladha MH, Lin N, Upton TM, Miller SJ, DiRenzo J, Pestell RG, Hinds PW, Dowdy SF, Brown M, Ewen ME.

Mol Cell Biol. 1997 Sep;17(9):5338-47.

25.

Ras signalling linked to the cell-cycle machinery by the retinoblastoma protein.

Peeper DS, Upton TM, Ladha MH, Neuman E, Zalvide J, Bernards R, DeCaprio JA, Ewen ME.

Nature. 1997 Mar 13;386(6621):177-81. Erratum in: Nature 1997 Apr 3;386(6624):521.

PMID:
9062190
26.
27.

p53 and translational control.

Ewen ME, Miller SJ.

Biochim Biophys Acta. 1996 Mar 18;1242(3):181-4. Review.

PMID:
8603071
28.

Multiple mechanisms of p16INK4A inactivation in non-small cell lung cancer cell lines.

Shapiro GI, Park JE, Edwards CD, Mao L, Merlo A, Sidransky D, Ewen ME, Rollins BJ.

Cancer Res. 1995 Dec 15;55(24):6200-9.

29.
30.

p53-dependent repression of CDK4 translation in TGF-beta-induced G1 cell-cycle arrest.

Ewen ME, Oliver CJ, Sluss HK, Miller SJ, Peeper DS.

Genes Dev. 1995 Jan 15;9(2):204-17.

31.

Negative regulation of the growth-promoting transcription factor E2F-1 by a stably bound cyclin A-dependent protein kinase.

Krek W, Ewen ME, Shirodkar S, Arany Z, Kaelin WG Jr, Livingston DM.

Cell. 1994 Jul 15;78(1):161-72.

PMID:
8033208
32.

Molecular cloning and functional analysis of the adenovirus E1A-associated 300-kD protein (p300) reveals a protein with properties of a transcriptional adaptor.

Eckner R, Ewen ME, Newsome D, Gerdes M, DeCaprio JA, Lawrence JB, Livingston DM.

Genes Dev. 1994 Apr 15;8(8):869-84.

33.

The cell cycle and the retinoblastoma protein family.

Ewen ME.

Cancer Metastasis Rev. 1994 Mar;13(1):45-66. Review.

PMID:
8143345
34.

TGF beta inhibition of Cdk4 synthesis is linked to cell cycle arrest.

Ewen ME, Sluss HK, Whitehouse LL, Livingston DM.

Cell. 1993 Sep 24;74(6):1009-20.

PMID:
8402878
35.

Functional interactions of the retinoblastoma protein with mammalian D-type cyclins.

Ewen ME, Sluss HK, Sherr CJ, Matsushime H, Kato J, Livingston DM.

Cell. 1993 May 7;73(3):487-97.

PMID:
8343202
36.

A- and B-type cyclins differentially modulate substrate specificity of cyclin-cdk complexes.

Peeper DS, Parker LL, Ewen ME, Toebes M, Hall FL, Xu M, Zantema A, van der Eb AJ, Piwnica-Worms H.

EMBO J. 1993 May;12(5):1947-54.

37.
38.

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins.

Matsushime H, Ewen ME, Strom DK, Kato JY, Hanks SK, Roussel MF, Sherr CJ.

Cell. 1992 Oct 16;71(2):323-34.

PMID:
1423597
39.

Interaction between human cyclin A and adenovirus E1A-associated p107 protein.

Faha B, Ewen ME, Tsai LH, Livingston DM, Harlow E.

Science. 1992 Jan 3;255(5040):87-90.

PMID:
1532458
40.

Interaction of p107 with cyclin A independent of complex formation with viral oncoproteins.

Ewen ME, Faha B, Harlow E, Livingston DM.

Science. 1992 Jan 3;255(5040):85-7.

PMID:
1532457
41.
42.
43.
44.

An N-terminal transformation-governing sequence of SV40 large T antigen contributes to the binding of both p110Rb and a second cellular protein, p120.

Ewen ME, Ludlow JW, Marsilio E, DeCaprio JA, Millikan RC, Cheng SH, Paucha E, Livingston DM.

Cell. 1989 Jul 28;58(2):257-67.

PMID:
2526683
45.

In vitro replication and transcription of the segmented double-stranded RNA bacteriophage phi 6.

Ewen ME, Revel HR.

Virology. 1988 Aug;165(2):489-98. Erratum in: Virology 1988 Dec;167(2):661.

PMID:
3407151
46.

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