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Items: 49

1.

Immune dysregulation and Osteosarcoma: Staphylococcus aureus downregulates TGF-β and heightens the inflammatory signature in human and canine macrophages suppressed by osteosarcoma.

Tuohy JL, Somarelli JA, Borst LB, Eward WC, Lascelles BDX, Fogle JE.

Vet Comp Oncol. 2019 Aug 17. doi: 10.1111/vco.12529. [Epub ahead of print]

PMID:
31420936
2.

Epidemiologic and survival trends in adult primary bone tumors of the spine.

Kerr DL, Dial BL, Lazarides AL, Catanzano AA, Lane WO, Blazer DG 3rd, Brigman BE, Mendoza-Lattes S, Eward WC, Erickson ME.

Spine J. 2019 Jul 12. pii: S1529-9430(19)30846-0. doi: 10.1016/j.spinee.2019.07.003. [Epub ahead of print]

PMID:
31306757
3.

E-Cadherin Represses Anchorage-Independent Growth in Sarcomas through Both Signaling and Mechanical Mechanisms.

Jolly MK, Ware KE, Xu S, Gilja S, Shetler S, Yang Y, Wang X, Austin RG, Runyambo D, Hish AJ, Bartholf DeWitt S, George JT, Kreulen RT, Boss MK, Lazarides AL, Kerr DL, Gerber DG, Sivaraj D, Armstrong AJ, Dewhirst MW, Eward WC, Levine H, Somarelli JA.

Mol Cancer Res. 2019 Jun;17(6):1391-1402. doi: 10.1158/1541-7786.MCR-18-0763. Epub 2019 Mar 12.

PMID:
30862685
4.

An Integrative Systems Biology and Experimental Approach Identifies Convergence of Epithelial Plasticity, Metabolism, and Autophagy to Promote Chemoresistance.

Xu S, Ware KE, Ding Y, Kim SY, Sheth MU, Rao S, Chan W, Armstrong AJ, Eward WC, Jolly MK, Somarelli JA.

J Clin Med. 2019 Feb 7;8(2). pii: E205. doi: 10.3390/jcm8020205.

5.

Microsurgery in musculoskeletal oncology.

Kontogeorgakos VA, Eward WC, Brigman BE.

Eur J Orthop Surg Traumatol. 2019 Feb;29(2):271-278. doi: 10.1007/s00590-019-02373-y. Epub 2019 Jan 8. Review.

PMID:
30623252
6.

Beyond Mirels: Factors Influencing Surgical Outcome of Metastasis to the Extremities in the Modern Era.

Scott E, Klement MR, Brigman BE, Eward WC.

J Surg Orthop Adv. Fall 2018;27(3):178-186.

PMID:
30489242
7.

Soft Tissue Sarcoma of the Extremities: What Is the Value of Treating at High-volume Centers?

Lazarides AL, Kerr DL, Nussbaum DP, Kreulen RT, Somarelli JA, Blazer DG 3rd, Brigman BE, Eward WC.

Clin Orthop Relat Res. 2019 Apr;477(4):718-727. doi: 10.1097/01.blo.0000533623.60399.1b.

PMID:
30485258
8.

Genetic determinants of childhood and adult height associated with osteosarcoma risk.

Zhang C, Morimoto LM, de Smith AJ, Hansen HM, Gonzalez-Maya J, Endicott AA, Smirnov IV, Metayer C, Wei Q, Eward WC, Wiemels JL, Walsh KM.

Cancer. 2018 Sep 15;124(18):3742-3752. doi: 10.1002/cncr.31645. Epub 2018 Oct 12.

PMID:
30311632
9.

Race is an independent predictor of survival in patients with soft tissue sarcoma of the extremities.

Lazarides AL, Visgauss JD, Nussbaum DP, Green CL, Blazer DG 3rd, Brigman BE, Eward WC.

BMC Cancer. 2018 Apr 27;18(1):488. doi: 10.1186/s12885-018-4397-3.

10.

Superficial Soft-Tissue Sarcomas Rarely Require Advanced Soft-Tissue Reconstruction following Resection.

Eward WC, Lazarides AL, Griffin AM, O'Donnell PW, Sternheim A, O'Neill A, Hofer SO, Ferguson PC, Wunder JS.

Plast Reconstr Surg Glob Open. 2017 Nov 13;5(11):e1553. doi: 10.1097/GOX.0000000000001553. eCollection 2017 Nov.

11.

Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.

Huang J, Chen M, Whitley MJ, Kuo HC, Xu ES, Walens A, Mowery YM, Van Mater D, Eward WC, Cardona DM, Luo L, Ma Y, Lopez OM, Nelson CE, Robinson-Hamm JN, Reddy A, Dave SS, Gersbach CA, Dodd RD, Kirsch DG.

Nat Commun. 2017 Jul 10;8:15999. doi: 10.1038/ncomms15999.

12.

NF1+/- Hematopoietic Cells Accelerate Malignant Peripheral Nerve Sheath Tumor Development without Altering Chemotherapy Response.

Dodd RD, Lee CL, Overton T, Huang W, Eward WC, Luo L, Ma Y, Ingram DR, Torres KE, Cardona DM, Lazar AJ, Kirsch DG.

Cancer Res. 2017 Aug 15;77(16):4486-4497. doi: 10.1158/0008-5472.CAN-16-2643. Epub 2017 Jun 23.

13.

Vascularized Fibula-Based Physis Transfer: A Follow-Up Study of Longitudinal Bone Growth and Complications.

Shammas RL, Avashia YJ, Farjat AE, Catanzano AA, Levin LS, Eward WC, Brigman BE, Erdmann D.

Plast Reconstr Surg Glob Open. 2017 May 25;5(5):e1352. doi: 10.1097/GOX.0000000000001352. eCollection 2017 May.

14.

Tumors of the Epiphyses.

Grimm NL, Tainter DM, Eward WC, Brigman BE.

JBJS Rev. 2017 May;5(5):e4. doi: 10.2106/JBJS.RVW.16.00080. Review. No abstract available.

PMID:
28538290
15.

The stability of the hip after the use of a proximal femoral endoprosthesis for oncological indications: analysis of variables relating to the patient and the surgical technique.

Henderson ER, Keeney BJ, Pala E, Funovics PT, Eward WC, Groundland JS, Ehrlichman LK, Puchner SS, Brigman BE, Ready JE, Temple HT, Ruggieri P, Windhager R, Letson GD, Hornicek FJ.

Bone Joint J. 2017 Apr;99-B(4):531-537. doi: 10.1302/0301-620X.99B4.BJJ-2016-0960.R1.

PMID:
28385944
16.

Synovial Chondromatosis.

Neumann JA, Garrigues GE, Brigman BE, Eward WC.

JBJS Rev. 2016 May 10;4(5). pii: 01874474-201605000-00005. doi: 10.2106/JBJS.RVW.O.00054.

PMID:
27490219
17.

Mesenchymal-Epithelial Transition in Sarcomas Is Controlled by the Combinatorial Expression of MicroRNA 200s and GRHL2.

Somarelli JA, Shetler S, Jolly MK, Wang X, Bartholf Dewitt S, Hish AJ, Gilja S, Eward WC, Ware KE, Levine H, Armstrong AJ, Garcia-Blanco MA.

Mol Cell Biol. 2016 Sep 12;36(19):2503-13. doi: 10.1128/MCB.00373-16. Print 2016 Oct 1.

18.

A Novel Imaging System Distinguishes Neoplastic from Normal Tissue During Resection of Soft Tissue Sarcomas and Mast Cell Tumors in Dogs.

Bartholf DeWitt S, Eward WC, Eward CA, Lazarides AL, Whitley MJ, Ferrer JM, Brigman BE, Kirsch DG, Berg J.

Vet Surg. 2016 Aug;45(6):715-22. doi: 10.1111/vsu.12487. Epub 2016 Jun 9.

19.

A Fluorescence-Guided Laser Ablation System for Removal of Residual Cancer in a Mouse Model of Soft Tissue Sarcoma.

Lazarides AL, Whitley MJ, Strasfeld DB, Cardona DM, Ferrer JM, Mueller JL, Fu HL, Bartholf DeWitt S, Brigman BE, Ramanujam N, Kirsch DG, Eward WC.

Theranostics. 2016 Jan 1;6(2):155-66. doi: 10.7150/thno.13536. eCollection 2016.

20.

A mouse-human phase 1 co-clinical trial of a protease-activated fluorescent probe for imaging cancer.

Whitley MJ, Cardona DM, Lazarides AL, Spasojevic I, Ferrer JM, Cahill J, Lee CL, Snuderl M, Blazer DG 3rd, Hwang ES, Greenup RA, Mosca PJ, Mito JK, Cuneo KC, Larrier NA, O'Reilly EK, Riedel RF, Eward WC, Strasfeld DB, Fukumura D, Jain RK, Lee WD, Griffith LG, Bawendi MG, Kirsch DG, Brigman BE.

Sci Transl Med. 2016 Jan 6;8(320):320ra4. doi: 10.1126/scitranslmed.aad0293.

21.

Innovations in Intraoperative Tumor Visualization.

Visgauss JD, Eward WC, Brigman BE.

Orthop Clin North Am. 2016 Jan;47(1):253-64. doi: 10.1016/j.ocl.2015.08.023. Review.

PMID:
26614939
22.

Myogenic transcription factors regulate pro-metastatic miR-182.

Dodd RD, Sachdeva M, Mito JK, Eward WC, Brigman BE, Ma Y, Dodd L, Kim Y, Lev D, Kirsch DG.

Oncogene. 2016 Apr 7;35(14):1868-75. doi: 10.1038/onc.2015.252. Epub 2015 Aug 3.

23.

Simultaneous Primary Presacral Myelolipomas: Case Report and Review of the Literature.

Lazarides AL, Scott EJ, Cardona DM, Blazer DG 3rd, Brigman BE, Eward WC.

J Gastrointest Cancer. 2016 Sep;47(3):331-5. doi: 10.1007/s12029-015-9749-5. Review. No abstract available.

PMID:
26164122
24.

Comparison of Acute Histologic and Biomechanical Effects of Radiofrequency Ablation and Cryoablation on Periarticular Structures in a Swine Model.

Vikingstad EM, de Ridder GG, Glisson RR, Cardona DM, DiPalma D, Eward WC, Brigman BE, Nelson RC, Kim CY.

J Vasc Interv Radiol. 2015 Aug;26(8):1221-1228.e1. doi: 10.1016/j.jvir.2015.04.013. Epub 2015 Jun 9.

PMID:
26065927
25.

The Use of Radiation Therapy in Well-Differentiated Soft Tissue Sarcoma of the Extremities: An NCDB Review.

Lazarides AL, Eward WC, Speicher PJ, Hou CH, Nussbaum DP, Green C, Blazer DG 3rd, Kirsch DG, Brigman BE.

Sarcoma. 2015;2015:186581. doi: 10.1155/2015/186581. Epub 2015 May 7.

26.

The use of radiation therapy in localized high-grade soft tissue sarcoma and potential impact on survival.

Hou CH, Lazarides AL, Speicher PJ, Nussbaum DP, Blazer DG 3rd, Kirsch DG, Brigman BE, Eward WC.

Ann Surg Oncol. 2015 Sep;22(9):2831-8. doi: 10.1245/s10434-015-4639-4. Epub 2015 Jun 4.

PMID:
26040605
27.

Histological Evaluation of Tendon-Bone Healing of an Anterior Cruciate Ligament Hamstring Graft in a 14-Year-Old Boy.

Lazarides AL, Eward WC, Green K, Cardona DM, Brigman BE, Taylor DC.

Am J Sports Med. 2015 Aug;43(8):1935-40. doi: 10.1177/0363546515584040. Epub 2015 May 12. No abstract available.

PMID:
25968884
28.

Extranodal Castleman disease of the extremities: a case report and review of the literature.

Eward WC, DeWitt SB, Brigman BE, Kontogeorgakos V, Lagoo AS.

Skeletal Radiol. 2014 Nov;43(11):1627-31. doi: 10.1007/s00256-014-1945-z. Epub 2014 Jun 27. Review.

PMID:
24970669
29.

The effect of the setting of a positive surgical margin in soft tissue sarcoma.

O'Donnell PW, Griffin AM, Eward WC, Sternheim A, Catton CN, Chung PW, O'Sullivan B, Ferguson PC, Wunder JS.

Cancer. 2014 Sep 15;120(18):2866-75. doi: 10.1002/cncr.28793. Epub 2014 Jun 3.

30.

Can Experienced Observers Differentiate between Lipoma and Well-Differentiated Liposarcoma Using Only MRI?

O'Donnell PW, Griffin AM, Eward WC, Sternheim A, White LM, Wunder JS, Ferguson PC.

Sarcoma. 2013;2013:982784. doi: 10.1155/2013/982784. Epub 2013 Dec 9.

31.

The vascularized fibular graft in the pediatric upper extremity: a durable, biological solution to large oncologic defects.

Zelenski N, Brigman BE, Levin LS, Erdmann D, Eward WC.

Sarcoma. 2013;2013:321201. doi: 10.1155/2013/321201. Epub 2013 Oct 7.

32.

Pancarpal synovial and tenosynovial chondromatosis in a 65-year-old man: a highly unusual presentation of a common condition.

Mata BA, Eward WC, Brigman BE.

Am J Orthop (Belle Mead NJ). 2013 Aug;42(8):E60-3. Review.

PMID:
24078960
33.

Early follow-up of a custom non-fluted diaphyseal press-fit tumour prosthesis.

O'Donnell PW, Griffin AM, Eward WC, Sternheim A, Wunder JS, Ferguson PC.

Int Orthop. 2014 Jan;38(1):123-7. doi: 10.1007/s00264-013-2078-z. Epub 2013 Sep 5.

34.

Internal fixation of radiation-induced pathological fractures of the femur has a high rate of failure.

Sternheim A, Saidi K, Lochab J, O'Donnell PW, Eward WC, Griffin A, Wunder JS, Ferguson P.

Bone Joint J. 2013 Aug;95-B(8):1144-8. doi: 10.1302/0301-620X.95B8.31832.

PMID:
23908434
35.

The phosphaturic mesenchymal tumor: why is definitive diagnosis and curative surgery often delayed?

Ledford CK, Zelenski NA, Cardona DM, Brigman BE, Eward WC.

Clin Orthop Relat Res. 2013 Nov;471(11):3618-25. doi: 10.1007/s11999-013-3178-1. Epub 2013 Jul 19.

36.

NF1 deletion generates multiple subtypes of soft-tissue sarcoma that respond to MEK inhibition.

Dodd RD, Mito JK, Eward WC, Chitalia R, Sachdeva M, Ma Y, Barretina J, Dodd L, Kirsch DG.

Mol Cancer Ther. 2013 Sep;12(9):1906-17. doi: 10.1158/1535-7163.MCT-13-0189. Epub 2013 Jul 15.

37.

Practical radiation oncology for extremity sarcomas.

Larrier NA, Kirsch DG, Riedel RF, Levinson H, Eward WC, Brigman BE.

Surg Oncol Clin N Am. 2013 Jul;22(3):433-43. doi: 10.1016/j.soc.2013.02.004. Epub 2013 Mar 13. Review.

PMID:
23622072
38.

A novel imaging system permits real-time in vivo tumor bed assessment after resection of naturally occurring sarcomas in dogs.

Eward WC, Mito JK, Eward CA, Carter JE, Ferrer JM, Kirsch DG, Brigman BE.

Clin Orthop Relat Res. 2013 Mar;471(3):834-42. doi: 10.1007/s11999-012-2560-8.

39.

The vascularized fibular graft in precollapse osteonecrosis: is long-term hip preservation possible?

Eward WC, Rineer CA, Urbaniak JR, Richard MJ, Ruch DS.

Clin Orthop Relat Res. 2012 Oct;470(10):2819-26. doi: 10.1007/s11999-012-2429-x. Epub 2012 Jun 26.

40.

Training femoral neck screw insertion skills to surgical trainees: computer-assisted surgery versus conventional fluoroscopic technique.

Nousiainen MT, Omoto DM, Zingg PO, Weil YA, Mardam-Bey SW, Eward WC.

J Orthop Trauma. 2013 Feb;27(2):87-92. doi: 10.1097/BOT.0b013e3182604b49.

41.

Surgical treatment and prognosis in patients with high-grade soft tissue malignant fibrous histiocytoma of the extremities.

Vasileios KA, Eward WC, Brigman BE.

Arch Orthop Trauma Surg. 2012 Jul;132(7):955-61. doi: 10.1007/s00402-012-1510-y. Epub 2012 Apr 10.

PMID:
22487849
42.

Intraoperative detection and removal of microscopic residual sarcoma using wide-field imaging.

Mito JK, Ferrer JM, Brigman BE, Lee CL, Dodd RD, Eward WC, Marshall LF, Cuneo KC, Carter JE, Ramasunder S, Kim Y, Lee WD, Griffith LG, Bawendi MG, Kirsch DG.

Cancer. 2012 Nov 1;118(21):5320-30. doi: 10.1002/cncr.27458. Epub 2012 Mar 21.

43.

[Femur reconstruction using combined autologous fibula transfer and humeral allograft].

Kokosis G, Stolberg-Stolberg J, Eward WC, Richard MJ, Hollenbeck ST, Levinson H, Brigman BE, Erdmann D.

Chirurg. 2011 Dec;82(12):1120-3. doi: 10.1007/s00104-011-2165-x. German.

PMID:
21901467
44.

Case report: lead toxicity associated with an extra-articular retained missile 14 years after injury.

Eward WC, Darcey D, Dodd LG, Zura RD.

J Surg Orthop Adv. 2011 Winter;20(4):241-6.

PMID:
22381417
45.

Pseudotumor with superimposed periprosthetic infection following metal-on-metal total hip arthroplasty: a case report.

Watters TS, Eward WC, Hallows RK, Dodd LG, Wellman SS, Bolognesi MP.

J Bone Joint Surg Am. 2010 Jul 7;92(7):1666-9. doi: 10.2106/JBJS.I.01208. No abstract available.

PMID:
20595575
46.

Cross species genomic analysis identifies a mouse model as undifferentiated pleomorphic sarcoma/malignant fibrous histiocytoma.

Mito JK, Riedel RF, Dodd L, Lahat G, Lazar AJ, Dodd RD, Stangenberg L, Eward WC, Hornicek FJ, Yoon SS, Brigman BE, Jacks T, Lev D, Mukherjee S, Kirsch DG.

PLoS One. 2009 Nov 30;4(11):e8075. doi: 10.1371/journal.pone.0008075.

47.

Free vascularized fibular graft reconstruction of large skeletal defects after tumor resection.

Eward WC, Kontogeorgakos V, Levin LS, Brigman BE.

Clin Orthop Relat Res. 2010 Feb;468(2):590-8. doi: 10.1007/s11999-009-1053-x. Epub 2009 Aug 22.

48.

Immunohistochemistry of the canine vomeronasal organ.

Dennis JC, Allgier JG, Desouza LS, Eward WC, Morrison EE.

J Anat. 2003 Sep;203(3):329-38.

49.

Immunohistochemistry of the canine vomeronasal organ.

Dennis JC, Allgier JG, Desouza LS, Eward WC, Morrison EE.

J Anat. 2003 Jun;202(6):515-24. Corrected and republished in: J Anat. 2003 Sep;203(3):329-38.

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