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Items: 1 to 50 of 56

1.

Metabolic Biomarkers of Ageing in C57BL/6J Wild-Type and Flavin-Containing Monooxygenase 5 (FMO5)-Knockout Mice.

Varshavi D, Scott FH, Varshavi D, Veeravalli S, Phillips IR, Veselkov K, Strittmatter N, Takats Z, Shephard EA, Everett JR.

Front Mol Biosci. 2018 Apr 9;5:28. doi: 10.3389/fmolb.2018.00028. eCollection 2018.

2.

NMR-based pharmacometabonomics: A new paradigm for personalised or precision medicine.

Everett JR.

Prog Nucl Magn Reson Spectrosc. 2017 Nov;102-103:1-14. doi: 10.1016/j.pnmrs.2017.04.003. Epub 2017 May 6. Review.

PMID:
29157489
3.

From Metabonomics to Pharmacometabonomics: The Role of Metabolic Profiling in Personalized Medicine.

Everett JR.

Front Pharmacol. 2016 Sep 8;7:297. doi: 10.3389/fphar.2016.00297. eCollection 2016. Review.

4.

Plate-based diversity subset screening generation 2: an improved paradigm for high-throughput screening of large compound files.

Bell AS, Bradley J, Everett JR, Loesel J, McLoughlin D, Mills J, Peakman MC, Sharp RE, Williams C, Zhu H.

Mol Divers. 2016 Nov;20(4):789-803. Epub 2016 Sep 8.

5.

New Methodology for Known Metabolite Identification in Metabonomics/Metabolomics: Topological Metabolite Identification Carbon Efficiency (tMICE).

Sanchon-Lopez B, Everett JR.

J Proteome Res. 2016 Sep 2;15(9):3405-19. doi: 10.1021/acs.jproteome.6b00631. Epub 2016 Aug 19.

6.

A guide to the identification of metabolites in NMR-based metabonomics/metabolomics experiments.

Dona AC, Kyriakides M, Scott F, Shephard EA, Varshavi D, Veselkov K, Everett JR.

Comput Struct Biotechnol J. 2016 Mar 9;14:135-53. doi: 10.1016/j.csbj.2016.02.005. eCollection 2016.

7.

Academic drug discovery: current status and prospects.

Everett JR.

Expert Opin Drug Discov. 2015;10(9):937-44. doi: 10.1517/17460441.2015.1059816. Epub 2015 Jun 19. Review.

PMID:
26088126
8.

Pharmacometabonomics in humans: a new tool for personalized medicine.

Everett JR.

Pharmacogenomics. 2015;16(7):737-54. doi: 10.2217/pgs.15.20. Epub 2015 May 1. Review.

PMID:
25929853
9.

A new paradigm for known metabolite identification in metabonomics/metabolomics: metabolite identification efficiency.

Everett JR.

Comput Struct Biotechnol J. 2015 Jan 27;13:131-44. doi: 10.1016/j.csbj.2015.01.002. eCollection 2015.

10.

Orphan nuclear receptor NR4A2 induces transcription of the immunomodulatory peptide hormone prolactin.

McCoy JM, Walkenhorst DE, McCauley KS, Elaasar H, Everett JR, Mix KS.

J Inflamm (Lond). 2015 Feb 18;12:13. doi: 10.1186/s12950-015-0059-2. eCollection 2015.

11.

Pharmacometabonomics and personalized medicine.

Everett JR, Loo RL, Pullen FS.

Ann Clin Biochem. 2013 Nov;50(Pt 6):523-45. doi: 10.1177/0004563213497929. Epub 2013 Jul 25. Review.

PMID:
23888060
12.

Plate-based diversity subset screening: an efficient paradigm for high throughput screening of a large screening file.

Bell AS, Bradley J, Everett JR, Knight M, Loesel J, Mathias J, McLoughlin D, Mills J, Sharp RE, Williams C, Wood TP.

Mol Divers. 2013 May;17(2):319-35. doi: 10.1007/s11030-013-9438-x. Epub 2013 Apr 5.

PMID:
23559278
13.

Report on the 10th anniversary of international drug discovery science and technology conference, 8 - 10 november 2012, nanjing, china.

Everett JR.

Expert Opin Drug Discov. 2013 Mar;8(3):357-61. doi: 10.1517/17460441.2013.762353. Epub 2013 Jan 23.

PMID:
23339328
14.

Shaping a screening file for maximal lead discovery efficiency and effectiveness: elimination of molecular redundancy.

Bakken GA, Bell AS, Boehm M, Everett JR, Gonzales R, Hepworth D, Klug-McLeod JL, Lanfear J, Loesel J, Mathias J, Wood TP.

J Chem Inf Model. 2012 Nov 26;52(11):2937-49. doi: 10.1021/ci300372a. Epub 2012 Oct 31.

PMID:
23062111
15.

Pharmacometabonomic characterization of xenobiotic and endogenous metabolic phenotypes that account for inter-individual variation in isoniazid-induced toxicological response.

Cunningham K, Claus SP, Lindon JC, Holmes E, Everett JR, Nicholson JK, Coen M.

J Proteome Res. 2012 Sep 7;11(9):4630-42. doi: 10.1021/pr300430u. Epub 2012 Aug 9.

PMID:
22873827
16.

Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy.

Nicholson JK, Everett JR, Lindon JC.

Expert Opin Drug Metab Toxicol. 2012 Feb;8(2):135-9. doi: 10.1517/17425255.2012.646987. Epub 2012 Jan 17.

PMID:
22248264
17.

Pharmacometabonomic identification of a significant host-microbiome metabolic interaction affecting human drug metabolism.

Clayton TA, Baker D, Lindon JC, Everett JR, Nicholson JK.

Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14728-33. doi: 10.1073/pnas.0904489106. Epub 2009 Aug 10.

18.

An integrated metabonomic approach to describe temporal metabolic disregulation induced in the rat by the model hepatotoxin allyl formate.

Yap IK, Clayton TA, Tang H, Everett JR, Hanton G, Provost JP, Le Net JL, Charuel C, Lindon JC, Nicholson JK.

J Proteome Res. 2006 Oct;5(10):2675-84.

PMID:
17022638
19.

Hepatotoxin-induced hypertyrosinemia and its toxicological significance.

Clayton TA, Lindon JC, Everett JR, Charuel C, Hanton G, Le Net JL, Provost JP, Nicholson JK.

Arch Toxicol. 2007 Mar;81(3):201-10. Epub 2006 Aug 11.

PMID:
16902803
20.

Pharmaco-metabonomic phenotyping and personalized drug treatment.

Clayton TA, Lindon JC, Cloarec O, Antti H, Charuel C, Hanton G, Provost JP, Le Net JL, Baker D, Walley RJ, Everett JR, Nicholson JK.

Nature. 2006 Apr 20;440(7087):1073-7.

PMID:
16625200
21.

NanoStore: a concept for logistical improvements of compound handling in high-throughput screening.

Benson N, Boyd HF, Everett JR, Fries J, Gribbon P, Haque N, Henco K, Jessen T, Martin WH, Mathewson TJ, Sharp RE, Spencer RW, Stuhmeier F, Wallace MS, Winkler D.

J Biomol Screen. 2005 Sep;10(6):573-80. Epub 2005 Jun 24.

PMID:
16103412
22.

Hepatotoxin-induced hypercreatinaemia and hypercreatinuria: their relationship to one another, to liver damage and to weakened nutritional status.

Clayton TA, Lindon JC, Everett JR, Charuel C, Hanton G, Le Net JL, Provost JP, Nicholson JK.

Arch Toxicol. 2004 Feb;78(2):86-96. Epub 2003 Oct 1.

PMID:
14520508
23.

An hypothesis for a mechanism underlying hepatotoxin-induced hypercreatinuria.

Clayton TA, Lindon JC, Everett JR, Charuel C, Hanton G, Le Net JL, Provost JP, Nicholson JK.

Arch Toxicol. 2003 Apr;77(4):208-17. Epub 2003 Feb 5.

PMID:
12698236
24.

Device-dependent activity estimation and decay correction of radionuclide mixtures with application to Tc-94m PET studies.

Smith MF, Daube-Witherspoon ME, Plascjak PS, Szajek LP, Carson RE, Everett JR, Green SL, Territo PR, Balaban RS, Bacharach SL, Eckelman WC.

Med Phys. 2001 Jan;28(1):36-45.

PMID:
11213920
25.

Adjuvant therapy of melanoma with interferon-alpha-2b is associated with mania and bipolar syndromes.

Greenberg DB, Jonasch E, Gadd MA, Ryan BF, Everett JR, Sober AJ, Mihm MA, Tanabe KK, Ott M, Haluska FG.

Cancer. 2000 Jul 15;89(2):356-62. Review.

PMID:
10918166
26.
27.

Structural elucidation of a novel erythromycin, 13-cyclopentyl-13-desethyl-erythromycin B, from a recombinant Saccharopolyspora erythraea strain, NRRL 2338 pIG/1.

Parsons IC, Everett JR, Pacey MS, Ruddock JC, Swanson AG, Thompson CM.

J Antibiot (Tokyo). 1999 Feb;52(2):190-2. No abstract available.

28.

High resolution 1H NMR spectroscopic studies on dynamic biochemical processes in incubated human seminal fluid samples.

Tomlins AM, Foxall PJ, Lynch MJ, Parkinson J, Everett JR, Nicholson JK.

Biochim Biophys Acta. 1998 Mar 2;1379(3):367-80.

PMID:
9545599
29.

Novel anthelmintic metabolites from an Aspergillus species; the aspergillimides.

Banks RM, Blanchflower SE, Everett JR, Manger BR, Reading C.

J Antibiot (Tokyo). 1997 Oct;50(10):840-6.

30.

On-line liquid chromatography coupled with high field NMR and mass spectrometry (LC-NMR-MS): a new technique for drug metabolite structure elucidation.

Burton KI, Everett JR, Newman MJ, Pullen FS, Richards DS, Swanson AG.

J Pharm Biomed Anal. 1997 Aug;15(12):1903-12.

PMID:
9278896
31.

Further novel milbemycin antibiotics from Streptomyces sp. E225. Fermentation, isolation and structure elucidation.

Baker GH, Blanchflower SE, Dorgan RJ, Everett JR, Manger BR, Reading CR, Readshaw SA, Shelley P.

J Antibiot (Tokyo). 1996 Mar;49(3):272-80.

32.

Visualisation of subchondral erosion in rat monoarticular arthritis by magnetic resonance imaging.

Carpenter TA, Everett JR, Hall LD, Harper GP, Hodgson RJ, James MF.

Skeletal Radiol. 1995 Jul;24(5):341-9.

PMID:
7570154
33.

High-resolution magnetic resonance imaging of arthritic pathology in the rat knee.

Carpenter TA, Everett JR, Hall LD, Harper GP, Hodgson RJ, James MF, Watson PJ.

Skeletal Radiol. 1994 Aug;23(6):429-37.

PMID:
7992108
34.

High resolution 1H NMR spectroscopic studies of the metabolism and excretion of ampicillin in rats and amoxycillin in rats and man.

Connor SC, Everett JR, Jennings KR, Nicholson JK, Woodnutt G.

J Pharm Pharmacol. 1994 Feb;46(2):128-34.

PMID:
8021801
35.

Further novel metabolites of the paraherquamide family.

Blanchflower SE, Banks RM, Everett JR, Reading C.

J Antibiot (Tokyo). 1993 Sep;46(9):1355-63.

36.

Impact of frequency range and input impedance on airway-tissue separation implied from transfer impedance.

Lutchen KR, Everett JR, Jackson AC.

J Appl Physiol (1985). 1993 Mar;74(3):1089-99.

PMID:
8482647
37.

New paraherquamide antibiotics with anthelmintic activity.

Blanchflower SE, Banks RM, Everett JR, Manger BR, Reading C.

J Antibiot (Tokyo). 1991 May;44(5):492-7. No abstract available.

38.

A novel series of milbemycin antibiotics from Streptomyces strain E225. II. Isolation, characterization, structure elucidation and solution conformations.

Baker GH, Dorgan RJ, Everett JR, Hood JD, Poulton ME.

J Antibiot (Tokyo). 1990 Sep;43(9):1069-76. Erratum in: J Antibiot (Tokyo) 1991 May;44(5):C-2.

39.

1H-NMR spectroscopy of biofluids and the investigation of xenobiotic-induced changes in liver biochemistry.

Sequeira S, So PW, Everett JR, Elcombe CR, Kelvin AS, Nicholson JK.

J Pharm Biomed Anal. 1990;8(8-12):945-9. No abstract available.

PMID:
2100647
40.

A study of flucloxacillin metabolites in rat urine by two-dimensional 1H, 19F COSY NMR.

Everett JR, Tyler JW, Woodnutt G.

J Pharm Biomed Anal. 1989;7(3):397-403. No abstract available.

PMID:
2488641
41.
42.

The degradation of temocillin, a 6 alpha-methoxypenicillin, and identification of the major degradation products.

Burton G, Dobson CR, Everett JR.

J Pharm Pharmacol. 1986 Oct;38(10):758-61.

PMID:
2878997
43.

Combination chemotherapy and radiation therapy. The medical management of epidural spinal cord compression from testicular cancer.

Friedman HM, Sheetz S, Levine HL, Everett JR, Hong WK.

Arch Intern Med. 1986 Mar;146(3):509-12.

PMID:
3954522
44.

19F NMR spectroscopy study of the metabolites of flucloxacillin in rat urine.

Everett JR, Jennings K, Woodnutt G.

J Pharm Pharmacol. 1985 Dec;37(12):869-73.

PMID:
2868093
45.

Parameters for the calculation of proton NMR chemical shifts of oligoribonucleotides.

Bell RA, Everett JR, Hughes DW, Coddington JM, Alkema D, Hader PA, Neilson T.

J Biomol Struct Dyn. 1985 Feb;2(4):693-707.

PMID:
2856017
46.
47.

Nearest-neighbor and next-nearest-neighbor effects in the proton NMR spectra of the oligoribonucleotides ApGpX and CpApX.

Everett JR, Hughes DW, Bell RA, Alkema D, Neilson T, Romaniuk PJ.

Biopolymers. 1980 Mar;19(3):557-73. No abstract available.

PMID:
7357069
48.

The effects of base sequence and dangling bases on the stability of short ribonucleic acid duplexes.

Neilson T, Romaniuk PJ, Alkema D, Hughes DW, Everett JR, Bell RA.

Nucleic Acids Symp Ser. 1980;(7):293-311.

PMID:
7255174
49.

Familial intraocular malignant melanoma: a case report.

Green GJ, Hong WK, Everett JR, Bhutani R, Amick RM.

Cancer. 1978 Jun;41(6):2481-3.

PMID:
657110
50.

Hydatid disease screening: Sanpete County, Utah, 1971-1976.

Barbour AG, Everett JR, Andersen FL, Nichols CR, Fukushima T, Kagan IG.

Am J Trop Med Hyg. 1978 Jan;27(1 Pt 1):94-100.

PMID:
626286

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