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The ubiquitin proteasome system and schizophrenia.

Luza S, Opazo CM, Bousman CA, Pantelis C, Bush AI, Everall IP.

Lancet Psychiatry. 2020 Feb 12. pii: S2215-0366(19)30520-6. doi: 10.1016/S2215-0366(19)30520-6. [Epub ahead of print] Review.


King's College London clarifies details of inquiry into publications by Eysenck and Grossarth-Maticek.

Everall IP.

BMJ. 2019 Nov 18;367:l6493. doi: 10.1136/bmj.l6493. No abstract available.


Impact of CYP1A2, CYP2C19, and CYP2D6 genotype- and phenoconversion-predicted enzyme activity on clozapine exposure and symptom severity.

Lesche D, Mostafa S, Everall I, Pantelis C, Bousman CA.

Pharmacogenomics J. 2019 Oct 15. doi: 10.1038/s41397-019-0108-y. [Epub ahead of print]


The schizophrenia genetics knowledgebase: a comprehensive update of findings from candidate gene studies.

Liu C, Kanazawa T, Tian Y, Mohamed Saini S, Mancuso S, Mostaid MS, Takahashi A, Zhang D, Zhang F, Yu H, Doo Shin H, Sub Cheong H, Ikeda M, Kubo M, Iwata N, Woo SI, Yue W, Kamatani Y, Shi Y, Li Z, Everall I, Pantelis C, Bousman C.

Transl Psychiatry. 2019 Aug 27;9(1):205. doi: 10.1038/s41398-019-0532-4.


Adverse effect of catechol-O-methyltransferase (COMT) Val158Met met/met genotype in methamphetamine-related executive dysfunction.

Cherner M, Watson CW, Saloner R, Halpin LE, Minassian A, Murray SS, Vaida F, Bousman C, Everall I; TMARC Group.

Addict Behav. 2019 Nov;98:106023. doi: 10.1016/j.addbeh.2019.06.012. Epub 2019 Jun 12.


Evidence for Network-Based Cortical Thickness Reductions in Schizophrenia.

Wannan CMJ, Cropley VL, Chakravarty MM, Bousman C, Ganella EP, Bruggemann JM, Weickert TW, Weickert CS, Everall I, McGorry P, Velakoulis D, Wood SJ, Bartholomeusz CF, Pantelis C, Zalesky A.

Am J Psychiatry. 2019 Jul 1;176(7):552-563. doi: 10.1176/appi.ajp.2019.18040380. Epub 2019 Jun 5.


Interrogating the Evolutionary Paradox of Schizophrenia: A Novel Framework and Evidence Supporting Recent Negative Selection of Schizophrenia Risk Alleles.

Liu C, Everall I, Pantelis C, Bousman C.

Front Genet. 2019 Apr 30;10:389. doi: 10.3389/fgene.2019.00389. eCollection 2019.


Exploring Heterogeneity on the Wisconsin Card Sorting Test in Schizophrenia Spectrum Disorders: A Cluster Analytical Investigation.

Carruthers SP, Gurvich CT, Meyer D; Australian Schizophrenia Research Bank, Bousman C, Everall IP, Neill E, Pantelis C, Sumner PJ, Tan EJ, Thomas EHX, Van Rheenen TE, Rossell SL.

J Int Neuropsychol Soc. 2019 Aug;25(7):750-760. doi: 10.1017/S1355617719000420.


Blood and brain protein levels of ubiquitin-conjugating enzyme E2K (UBE2K) are elevated in individuals with schizophrenia.

Meiklejohn H, Mostaid MS, Luza S, Mancuso SG, Kang D, Atherton S, Rothmond DA, Weickert CS, Opazo CM, Pantelis C, Bush AI, Everall IP, Bousman CA.

J Psychiatr Res. 2019 Jun;113:51-57. doi: 10.1016/j.jpsychires.2019.03.005. Epub 2019 Mar 8.


Elevated ubiquitinated proteins in brain and blood of individuals with schizophrenia.

Bousman CA, Luza S, Mancuso SG, Kang D, Opazo CM, Mostaid MS, Cropley V, McGorry P, Shannon Weickert C, Pantelis C, Bush AI, Everall IP.

Sci Rep. 2019 Feb 19;9(1):2307. doi: 10.1038/s41598-019-38490-1.


Insula Functional Connectivity in Schizophrenia: Subregions, Gradients, and Symptoms.

Tian Y, Zalesky A, Bousman C, Everall I, Pantelis C.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 Apr;4(4):399-408. doi: 10.1016/j.bpsc.2018.12.003. Epub 2018 Dec 13.


Brain network dynamics in schizophrenia: Reduced dynamism of the default mode network.

Kottaram A, Johnston LA, Cocchi L, Ganella EP, Everall I, Pantelis C, Kotagiri R, Zalesky A.

Hum Brain Mapp. 2019 May;40(7):2212-2228. doi: 10.1002/hbm.24519. Epub 2019 Jan 21.


The effects of a muscarinic receptor 1 gene variant on executive and non-executive cognition in schizophrenia spectrum disorders.

Carruthers SP, Cropley V, Bousman C, Everall IP, Neill E, Pantelis C, Sumner PJ, Tan EJ; Australian Schizophrenia Research Bank, Bozaoglu K, Thomas EHX, Van Rheenen TE, Gurvich CT, Rossell SL.

Psychiatry Res. 2019 Mar;273:178-180. doi: 10.1016/j.psychres.2019.01.032. Epub 2019 Jan 11.


Systematic review and critical appraisal of child abuse measurement instruments.

Saini SM, Hoffmann CR, Pantelis C, Everall IP, Bousman CA.

Psychiatry Res. 2019 Feb;272:106-113. doi: 10.1016/j.psychres.2018.12.068. Epub 2018 Dec 13.


Investigation of peripheral complement factors across stages of psychosis.

Laskaris L, Zalesky A, Weickert CS, Di Biase MA, Chana G, Baune BT, Bousman C, Nelson B, McGorry P, Everall I, Pantelis C, Cropley V.

Schizophr Res. 2019 Feb;204:30-37. doi: 10.1016/j.schres.2018.11.035. Epub 2018 Dec 6.


Hippocampal subfields and visuospatial associative memory across stages of schizophrenia-spectrum disorder.

Wannan CMJ, Cropley VL, Chakravarty MM, Van Rheenen TE, Mancuso S, Bousman C, Everall I, McGorry PD, Pantelis C, Bartholomeusz CF.

Psychol Med. 2019 Oct;49(14):2452-2462. doi: 10.1017/S0033291718003458. Epub 2018 Dec 4.


Mutations in the MAB_2299c TetR Regulator Confer Cross-Resistance to Clofazimine and Bedaquiline in Mycobacterium abscessus.

Richard M, Gutiérrez AV, Viljoen A, Rodriguez-Rincon D, Roquet-Baneres F, Blaise M, Everall I, Parkhill J, Floto RA, Kremer L.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01316-18. doi: 10.1128/AAC.01316-18. Print 2019 Jan.


An Interleukin-1 beta (IL1B) haplotype linked with psychosis transition is associated with IL1B gene expression and brain structure.

Mostaid MS, Dimitrakopoulos S, Wannan C, Cropley V, Weickert CS, Everall IP, Pantelis C, Bousman CA.

Schizophr Res. 2019 Feb;204:201-205. doi: 10.1016/j.schres.2018.09.008. Epub 2018 Sep 14.


Low levels of muscarinic M1 receptor-positive neurons in cortical layers III and V in Brodmann areas 9 and 17 from individuals with schizophrenia.

Scarr E, Hopper S, Vos V, Seo MS, Everall IP, Aumann TD, Chana G, Dean B.

J Psychiatry Neurosci. 2018 Aug;43(5):338-346.


Assessment of Placental Cortisol Pathway Gene Expression in Term Pregnant Women with Anxiety.

Sheehan PM, Bousman C, Komiti A, Judd F, Newman L, Tonge B, Castle D, Everall I.

Neuropsychobiology. 2019;77(1):1-7. doi: 10.1159/000490428. Epub 2018 Aug 15.


Depression, fatigue and neurocognitive deficits in chronic hepatitis C.

Yeoh SW, Holmes ACN, Saling MM, Everall IP, Nicoll AJ.

Hepatol Int. 2018 Jul;12(4):294-304. doi: 10.1007/s12072-018-9879-5. Epub 2018 Jun 21. Review.


Low levels of muscarinic M1 receptor-positive neurons in cortical layers III and V in Brodmann areas 9 and 17 from individuals with schizophrenia.

Scarr E, Hopper S, Vos V, Seo MS, Everall IP, Aumann TD, Chana G, Dean B.

J Psychiatry Neurosci. 2018 May 30;43(4):170202. doi: 10.1503/jpn.170202. [Epub ahead of print]


Decreased peripheral TNF alpha (TNF-α) mRNA expression in patients with treatment-resistant schizophrenia.

Mostaid MS, Pantelis C, Everall IP, Bousman CA.

Schizophr Res. 2018 Dec;202:387-388. doi: 10.1016/j.schres.2018.04.032. Epub 2018 Apr 26. No abstract available.


Graphene foam as a biocompatible scaffold for culturing human neurons.

D'Abaco GM, Mattei C, Nasr B, Hudson EJ, Alshawaf AJ, Chana G, Everall IP, Nayagam B, Dottori M, Skafidas E.

R Soc Open Sci. 2018 Mar 7;5(3):171364. doi: 10.1098/rsos.171364. eCollection 2018 Mar.


Downregulation of plasma SELENBP1 protein in patients with recent-onset schizophrenia.

Chau EJ, Mostaid MS, Cropley V, McGorry P, Pantelis C, Bousman CA, Everall IP.

Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jul 13;85:1-6. doi: 10.1016/j.pnpbp.2018.03.010. Epub 2018 Mar 22.


Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells.

Alshawaf AJ, Viventi S, Qiu W, D'Abaco G, Nayagam B, Erlichster M, Chana G, Everall I, Ivanusic J, Skafidas E, Dottori M.

Sci Rep. 2018 Jan 12;8(1):603. doi: 10.1038/s41598-017-19093-0.


No preliminary evidence of differences in astrocyte density within the white matter of the dorsolateral prefrontal cortex in autism.

Lee TT, Skafidas E, Dottori M, Zantomio D, Pantelis C, Everall I, Chana G.

Mol Autism. 2017 Dec 8;8:64. doi: 10.1186/s13229-017-0181-5. eCollection 2017.


Elevated peripheral expression of neuregulin-1 (NRG1) mRNA isoforms in clozapine-treated schizophrenia patients.

Mostaid MS, Lee TT, Chana G, Sundram S, Shannon Weickert C, Pantelis C, Everall I, Bousman C.

Transl Psychiatry. 2017 Dec 11;7(12):1280. doi: 10.1038/s41398-017-0041-2.


Peripheral Transcription of NRG-ErbB Pathway Genes Are Upregulated in Treatment-Resistant Schizophrenia.

Mostaid MS, Lee TT, Chana G, Sundram S, Shannon Weickert C, Pantelis C, Everall I, Bousman C.

Front Psychiatry. 2017 Nov 6;8:225. doi: 10.3389/fpsyt.2017.00225. eCollection 2017.


Genetic variation in cytokine genes and risk for transition to psychosis among individuals at ultra-high risk.

Bousman CA, Lee TY, Kim M, Lee J, Mostaid MS, Bang M, An SK, Everall IP, Pantelis C, Kwon JS.

Schizophr Res. 2018 May;195:589-590. doi: 10.1016/j.schres.2017.08.040. Epub 2017 Sep 13. No abstract available.


Genomic epidemiology of a national outbreak of post-surgical Mycobacterium abscessus wound infections in Brazil.

Everall I, Nogueira CL, Bryant JM, Sánchez-Busó L, Chimara E, Duarte RDS, Ramos JP, Lima KVB, Lopes ML, Palaci M, Kipnis A, Monego F, Floto RA, Parkhill J, Leão SC, Harris SR.

Microb Genom. 2017 May 3;3(5):e000111. doi: 10.1099/mgen.0.000111. eCollection 2017 May.


Schizophrenia genetics in the genome-wide era: a review of Japanese studies.

Kanazawa T, Bousman CA, Liu C, Everall IP.

NPJ Schizophr. 2017 Aug 30;3(1):27. doi: 10.1038/s41537-017-0028-2. Review.


PET imaging of putative microglial activation in individuals at ultra-high risk for psychosis, recently diagnosed and chronically ill with schizophrenia.

Di Biase MA, Zalesky A, O'keefe G, Laskaris L, Baune BT, Weickert CS, Olver J, McGorry PD, Amminger GP, Nelson B, Scott AM, Hickie I, Banati R, Turkheimer F, Yaqub M, Everall IP, Pantelis C, Cropley V.

Transl Psychiatry. 2017 Aug 29;7(8):e1225. doi: 10.1038/tp.2017.193.


Neuregulin-1 (NRG1) polymorphisms linked with psychosis transition are associated with enlarged lateral ventricles and white matter disruption in schizophrenia.

Bousman CA, Cropley V, Klauser P, Hess JL, Pereira A, Idrizi R, Bruggemann J, Mostaid MS, Lenroot R, Weickert TW, Glatt SJ, Everall IP, Sundram S, Zalesky A, Weickert CS, Pantelis C.

Psychol Med. 2018 Apr;48(5):801-809. doi: 10.1017/S0033291717002173. Epub 2017 Aug 22.


Meta-analysis supports GWAS-implicated link between GRM3 and schizophrenia risk.

Saini SM, Mancuso SG, Mostaid MS, Liu C, Pantelis C, Everall IP, Bousman CA.

Transl Psychiatry. 2017 Aug 8;7(8):e1196. doi: 10.1038/tp.2017.172.


Risk and resilience brain networks in treatment-resistant schizophrenia.

Ganella EP, Seguin C, Bartholomeusz CF, Whittle S, Bousman C, Wannan CMJ, Di Biase MA, Phassouliotis C, Everall I, Pantelis C, Zalesky A.

Schizophr Res. 2018 Mar;193:284-292. doi: 10.1016/j.schres.2017.07.014. Epub 2017 Jul 21.


White matter connectivity disruptions in early and chronic schizophrenia.

Di Biase MA, Cropley VL, Baune BT, Olver J, Amminger GP, Phassouliotis C, Bousman C, McGorry PD, Everall I, Pantelis C, Zalesky A.

Psychol Med. 2017 Dec;47(16):2797-2810. doi: 10.1017/S0033291717001313. Epub 2017 May 22.


Bringing Treponema into the spotlight.

Everall I, Sánchez-Busó L.

Nat Rev Microbiol. 2017 Mar 13;15(4):196. doi: 10.1038/nrmicro.2017.23. No abstract available.


Pathway-wide association study identifies five shared pathways associated with schizophrenia in three ancestral distinct populations.

Liu C, Bousman CA, Pantelis C, Skafidas E, Zhang D, Yue W, Everall IP.

Transl Psychiatry. 2017 Feb 21;7(2):e1037. doi: 10.1038/tp.2017.8.


Meta-analysis reveals associations between genetic variation in the 5' and 3' regions of Neuregulin-1 and schizophrenia.

Mostaid MS, Mancuso SG, Liu C, Sundram S, Pantelis C, Everall IP, Bousman CA.

Transl Psychiatry. 2017 Jan 17;7(1):e1004. doi: 10.1038/tp.2016.279.


Functional brain networks in treatment-resistant schizophrenia.

Ganella EP, Bartholomeusz CF, Seguin C, Whittle S, Bousman C, Phassouliotis C, Everall I, Pantelis C, Zalesky A.

Schizophr Res. 2017 Jun;184:73-81. doi: 10.1016/j.schres.2016.12.008. Epub 2016 Dec 20.


Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium.

Bryant JM, Grogono DM, Rodriguez-Rincon D, Everall I, Brown KP, Moreno P, Verma D, Hill E, Drijkoningen J, Gilligan P, Esther CR, Noone PG, Giddings O, Bell SC, Thomson R, Wainwright CE, Coulter C, Pandey S, Wood ME, Stockwell RE, Ramsay KA, Sherrard LJ, Kidd TJ, Jabbour N, Johnson GR, Knibbs LD, Morawska L, Sly PD, Jones A, Bilton D, Laurenson I, Ruddy M, Bourke S, Bowler IC, Chapman SJ, Clayton A, Cullen M, Daniels T, Dempsey O, Denton M, Desai M, Drew RJ, Edenborough F, Evans J, Folb J, Humphrey H, Isalska B, Jensen-Fangel S, Jönsson B, Jones AM, Katzenstein TL, Lillebaek T, MacGregor G, Mayell S, Millar M, Modha D, Nash EF, O'Brien C, O'Brien D, Ohri C, Pao CS, Peckham D, Perrin F, Perry A, Pressler T, Prtak L, Qvist T, Robb A, Rodgers H, Schaffer K, Shafi N, van Ingen J, Walshaw M, Watson D, West N, Whitehouse J, Haworth CS, Harris SR, Ordway D, Parkhill J, Floto RA.

Science. 2016 Nov 11;354(6313):751-757. doi: 10.1126/science.aaf8156.


High heterogeneity and low reliability in the diagnosis of major depression will impair the development of new drugs.

Lieblich SM, Castle DJ, Pantelis C, Hopwood M, Young AH, Everall IP.

BJPsych Open. 2015 Nov 17;1(2):e5-e7. eCollection 2015 Oct.


Serotonin transporter polymorphism (5HTTLPR), severe childhood abuse and depressive symptom trajectories in adulthood.

Nguyen TB, Gunn JM, Potiriadis M, Everall IP, Bousman CA.

BJPsych Open. 2015 Sep 22;1(1):104-109. eCollection 2015 Jun.


The Brain-Derived Neurotrophic Factor Val66Met Polymorphism Moderates the Effects of Childhood Abuse on Severity of Depressive Symptoms in a Time-Dependent Manner.

Webb C, Gunn JM, Potiriadis M, Everall IP, Bousman CA.

Front Psychiatry. 2016 Aug 29;7:151. doi: 10.3389/fpsyt.2016.00151. eCollection 2016.


Early origins of mental disorder - risk factors in the perinatal and infant period.

Newman L, Judd F, Olsson CA, Castle D, Bousman C, Sheehan P, Pantelis C, Craig JM, Komiti A, Everall I.

BMC Psychiatry. 2016 Jul 29;16:270. doi: 10.1186/s12888-016-0982-7. Review.


The distribution of muscarinic M1 receptors in the human hippocampus.

Scarr E, Seo MS, Aumann TD, Chana G, Everall IP, Dean B.

J Chem Neuroanat. 2016 Nov;77:187-192. doi: 10.1016/j.jchemneu.2016.07.006. Epub 2016 Jul 18.


Increased cortical expression of the zinc transporter SLC39A12 suggests a breakdown in zinc cellular homeostasis as part of the pathophysiology of schizophrenia.

Scarr E, Udawela M, Greenough MA, Neo J, Suk Seo M, Money TT, Upadhyay A, Bush AI, Everall IP, Thomas EA, Dean B.

NPJ Schizophr. 2016 Mar 9;2:16002. doi: 10.1038/npjschz.2016.2. eCollection 2016.


Neuregulin-1 and schizophrenia in the genome-wide association study era.

Mostaid MS, Lloyd D, Liberg B, Sundram S, Pereira A, Pantelis C, Karl T, Weickert CS, Everall IP, Bousman CA.

Neurosci Biobehav Rev. 2016 Sep;68:387-409. doi: 10.1016/j.neubiorev.2016.06.001. Epub 2016 Jun 6. Review.


Fibroblast growth factors 1 and 2 in cerebrospinal fluid are associated with HIV disease, methamphetamine use, and neurocognitive functioning.

Bharti AR, Woods SP, Ellis RJ, Cherner M, Rosario D, Potter M, Heaton RK, Everall IP, Masliah E, Grant I, Letendre SL.

HIV AIDS (Auckl). 2016 Apr 29;8:93-9. doi: 10.2147/HIV.S93306. eCollection 2016.

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