Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 64


Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables.

Wentworth JM, Bediaga NG, Giles LC, Ehlers M, Gitelman SE, Geyer S, Evans-Molina C, Harrison LC; Type 1 Diabetes TrialNet Study Group; Immune Tolerance Network Study Group.

Diabetologia. 2018 Aug 30. doi: 10.1007/s00125-018-4722-z. [Epub ahead of print]


Impaired Store-Operated Calcium Entry and STIM1 Loss Lead to Reduced Insulin Secretion and Increased Endoplasmic Reticulum Stress in the Diabetic β cell.

Kono T, Tong X, Taleb S, Bone RN, Iida H, Lee CC, Sohn P, Gilon P, Roe MW, Evans-Molina C.

Diabetes. 2018 Aug 21. pii: db171351. doi: 10.2337/db17-1351. [Epub ahead of print]


Biomarkers of islet beta cell stress and death in type 1 diabetes.

Sims EK, Evans-Molina C, Tersey SA, Eizirik DL, Mirmira RG.

Diabetologia. 2018 Aug 15. doi: 10.1007/s00125-018-4712-1. [Epub ahead of print] Review.


β Cell dysfunction exists more than 5 years before type 1 diabetes diagnosis.

Evans-Molina C, Sims EK, DiMeglio LA, Ismail HM, Steck AK, Palmer JP, Krischer JP, Geyer S, Xu P, Sosenko JM; Type 1 Diabetes TrialNet Study Group.

JCI Insight. 2018 Aug 9;3(15). pii: 120877. doi: 10.1172/jci.insight.120877. [Epub ahead of print]


Persistent elevations in circulating INS DNA among subjects with longstanding type 1 diabetes.

Neyman A, Nelson J, Tersey SA, Mirmira RG, Evans-Molina C, Sims EK.

Diabetes Obes Metab. 2018 Aug 2. doi: 10.1111/dom.13489. [Epub ahead of print]


Type 1 diabetes.

DiMeglio LA, Evans-Molina C, Oram RA.

Lancet. 2018 Jun 16;391(10138):2449-2462. doi: 10.1016/S0140-6736(18)31320-5. Review.


Restructuring of the Gut Microbiome by Intermittent Fasting Prevents Retinopathy and Prolongs Survival in db/db Mice.

Beli E, Yan Y, Moldovan L, Vieira CP, Gao R, Duan Y, Prasad R, Bhatwadekar A, White FA, Townsend SD, Chan L, Ryan CN, Morton D, Moldovan EG, Chu FI, Oudit GY, Derendorf H, Adorini L, Wang XX, Evans-Molina C, Mirmira RG, Boulton ME, Yoder MC, Li Q, Levi M, Busik JV, Grant MB.

Diabetes. 2018 Sep;67(9):1867-1879. doi: 10.2337/db18-0158. Epub 2018 Apr 30.


The influence of body mass index and age on C-peptide at the diagnosis of type 1 diabetes in children who participated in the diabetes prevention trial-type 1.

Sosenko JM, Geyer S, Skyler JS, Rafkin LE, Ismail HM, Libman IM, Liu YF, DiMeglio LA, Evans-Molina C, Palmer JP.

Pediatr Diabetes. 2018 May;19(3):403-409. doi: 10.1111/pedi.12609. Epub 2017 Nov 24.


The Role of Age and Excess Body Mass Index in Progression to Type 1 Diabetes in At-Risk Adults.

Ferrara CT, Geyer SM, Evans-Molina C, Libman IM, Becker DJ, Wentworth JM, Moran A, Gitelman SE, Redondo MJ; Type 1 Diabetes TrialNet Study Group.

J Clin Endocrinol Metab. 2017 Dec 1;102(12):4596-4603. doi: 10.1210/jc.2017-01490.


Dysglycemia and Index60 as Prediagnostic End Points for Type 1 Diabetes Prevention Trials.

Nathan BM, Boulware D, Geyer S, Atkinson MA, Colman P, Goland R, Russell W, Wentworth JM, Wilson DM, Evans-Molina C, Wherrett D, Skyler JS, Moran A, Sosenko JM; Type 1 Diabetes TrialNet and Diabetes Prevention Trial–Type 1 Study Groups.

Diabetes Care. 2017 Nov;40(11):1494-1499. doi: 10.2337/dc17-0916. Epub 2017 Aug 31.


Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation.

Hatanaka M, Anderson-Baucum E, Lakhter A, Kono T, Maier B, Tersey SA, Tanizawa Y, Evans-Molina C, Mirmira RG, Sims EK.

Sci Rep. 2017 Jun 19;7(1):3758. doi: 10.1038/s41598-017-03869-5.


Combination Immunotherapy for Type 1 Diabetes.

Bone RN, Evans-Molina C.

Curr Diab Rep. 2017 Jul;17(7):50. doi: 10.1007/s11892-017-0878-z. Review.


STEAP4 expression in human islets is associated with differences in body mass index, sex, HbA1c, and inflammation.

Gordon HM, Majithia N, MacDonald PE, Fox JEM, Sharma PR, Byrne FL, Hoehn KL, Evans-Molina C, Langman L, Brayman KL, Nunemaker CS.

Endocrine. 2017 Jun;56(3):528-537. doi: 10.1007/s12020-017-1297-2. Epub 2017 Apr 12.


Smoking and the risk of type 2 diabetes.

Maddatu J, Anderson-Baucum E, Evans-Molina C.

Transl Res. 2017 Jun;184:101-107. doi: 10.1016/j.trsl.2017.02.004. Epub 2017 Mar 6. Review.


MicroRNA 21 targets BCL2 mRNA to increase apoptosis in rat and human beta cells.

Sims EK, Lakhter AJ, Anderson-Baucum E, Kono T, Tong X, Evans-Molina C.

Diabetologia. 2017 Jun;60(6):1057-1065. doi: 10.1007/s00125-017-4237-z. Epub 2017 Mar 9.


Excess BMI in Childhood: A Modifiable Risk Factor for Type 1 Diabetes Development?

Ferrara CT, Geyer SM, Liu YF, Evans-Molina C, Libman IM, Besser R, Becker DJ, Rodriguez H, Moran A, Gitelman SE, Redondo MJ; Type 1 Diabetes TrialNet Study Group.

Diabetes Care. 2017 May;40(5):698-701. doi: 10.2337/dc16-2331. Epub 2017 Feb 15.


Inflammatory stress of pancreatic beta cells drives release of extracellular heat-shock protein 90α.

Ocaña GJ, Pérez L, Guindon L, Deffit SN, Evans-Molina C, Thurmond DC, Blum JS.

Immunology. 2017 Jun;151(2):198-210. doi: 10.1111/imm.12723. Epub 2017 Mar 13.


Biomarkers of β-Cell Stress and Death in Type 1 Diabetes.

Mirmira RG, Sims EK, Syed F, Evans-Molina C.

Curr Diab Rep. 2016 Oct;16(10):95. doi: 10.1007/s11892-016-0783-x. Review.


SERCA2 Deficiency Impairs Pancreatic β-Cell Function in Response to Diet-Induced Obesity.

Tong X, Kono T, Anderson-Baucum EK, Yamamoto W, Gilon P, Lebeche D, Day RN, Shull GE, Evans-Molina C.

Diabetes. 2016 Oct;65(10):3039-52. doi: 10.2337/db16-0084. Epub 2016 Aug 3.


Elevations in the Fasting Serum Proinsulin-to-C-Peptide Ratio Precede the Onset of Type 1 Diabetes.

Sims EK, Chaudhry Z, Watkins R, Syed F, Blum J, Ouyang F, Perkins SM, Mirmira RG, Sosenko J, DiMeglio LA, Evans-Molina C.

Diabetes Care. 2016 Sep;39(9):1519-26. doi: 10.2337/dc15-2849. Epub 2016 Jul 6.


Nucleic acid biomarkers of β cell stress and death in type 1 diabetes.

Syed F, Evans-Molina C.

Curr Opin Endocrinol Diabetes Obes. 2016 Aug;23(4):312-7. doi: 10.1097/MED.0000000000000261. Review.


The relationship between BMI and insulin resistance and progression from single to multiple autoantibody positivity and type 1 diabetes among TrialNet Pathway to Prevention participants.

Meah FA, DiMeglio LA, Greenbaum CJ, Blum JS, Sosenko JM, Pugliese A, Geyer S, Xu P, Evans-Molina C; Type 1 Diabetes TrialNet Study Group.

Diabetologia. 2016 Jun;59(6):1186-95. doi: 10.1007/s00125-016-3924-5. Epub 2016 Mar 19.


HLA-DRB1*15:01-DQA1*01:02-DQB1*06:02 Haplotype Protects Autoantibody-Positive Relatives From Type 1 Diabetes Throughout the Stages of Disease Progression.

Pugliese A, Boulware D, Yu L, Babu S, Steck AK, Becker D, Rodriguez H, DiMeglio L, Evans-Molina C, Harrison LC, Schatz D, Palmer JP, Greenbaum C, Eisenbarth GS, Sosenko JM; Type 1 Diabetes TrialNet Study Group.

Diabetes. 2016 Apr;65(4):1109-19. doi: 10.2337/db15-1105. Epub 2016 Jan 28.


CD40 promotes MHC class II expression on adipose tissue macrophages and regulates adipose tissue CD4+ T cells with obesity.

Morris DL, Oatmen KE, Mergian TA, Cho KW, DelProposto JL, Singer K, Evans-Molina C, O'Rourke RW, Lumeng CN.

J Leukoc Biol. 2016 Jun;99(6):1107-19. doi: 10.1189/jlb.3A0115-009R. Epub 2015 Dec 11.


Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells.

Xiong X, Wang G, Tao R, Wu P, Kono T, Li K, Ding WX, Tong X, Tersey SA, Harris RA, Mirmira RG, Evans-Molina C, Dong XC.

Diabetologia. 2016 Jan;59(1):151-60.


Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes.

Watkins RA, Evans-Molina C, Terrell JK, Day KH, Guindon L, Restrepo IA, Mirmira RG, Blum JS, DiMeglio LA.

Transl Res. 2016 Feb;168:96-106.e1. doi: 10.1016/j.trsl.2015.08.010. Epub 2015 Sep 4.


Elevations in Circulating Methylated and Unmethylated Preproinsulin DNA in New-Onset Type 1 Diabetes.

Fisher MM, Watkins RA, Blum J, Evans-Molina C, Chalasani N, DiMeglio LA, Mather KJ, Tersey SA, Mirmira RG.

Diabetes. 2015 Nov;64(11):3867-72. doi: 10.2337/db15-0430. Epub 2015 Jul 27.


SET7/9 Enzyme Regulates Cytokine-induced Expression of Inducible Nitric-oxide Synthase through Methylation of Lysine 4 at Histone 3 in the Islet β Cell.

Fujimaki K, Ogihara T, Morris DL, Oda H, Iida H, Fujitani Y, Mirmira RG, Evans-Molina C, Watada H.

J Biol Chem. 2015 Jul 3;290(27):16607-18. doi: 10.1074/jbc.M115.661777. Epub 2015 May 20.


Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes.

Filgueiras LR, Brandt SL, Wang S, Wang Z, Morris DL, Evans-Molina C, Mirmira RG, Jancar S, Serezani CH.

Sci Signal. 2015 Jan 27;8(361):ra10. doi: 10.1126/scisignal.2005568.


Pancreatic and Islet Development and Function: The Role of Thyroid Hormone.

Mastracci TL, Evans-Molina C.

J Endocrinol Diabetes Obes. 2014;2(3). pii: 1044.


From immunobiology to β-cell biology: the changing perspective on type 1 diabetes.

Maganti A, Evans-Molina C, Mirmira R.

Islets. 2014;6(2):e28778. doi: 10.4161/isl.28778.


Fetal hyperglycemia and a high-fat diet contribute to aberrant glucose tolerance and hematopoiesis in adult rats.

Blue EK, Ballman K, Boyle F, Oh E, Kono T, Quinney SK, Thurmond DC, Evans-Molina C, Haneline LS.

Pediatr Res. 2015 Feb;77(2):316-25. doi: 10.1038/pr.2014.185. Epub 2014 Nov 20.


Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell.

Johnson JS, Kono T, Tong X, Yamamoto WR, Zarain-Herzberg A, Merrins MJ, Satin LS, Gilon P, Evans-Molina C.

J Biol Chem. 2014 Nov 21;289(47):32798-810. doi: 10.1074/jbc.M114.575191. Epub 2014 Sep 30.


Palmitate induces mRNA translation and increases ER protein load in islet β-cells via activation of the mammalian target of rapamycin pathway.

Hatanaka M, Maier B, Sims EK, Templin AT, Kulkarni RN, Evans-Molina C, Mirmira RG.

Diabetes. 2014 Oct;63(10):3404-15. doi: 10.2337/db14-0105. Epub 2014 May 16.


Bisphenol A, obesity, and type 2 diabetes mellitus: genuine concern or unnecessary preoccupation?

Mirmira P, Evans-Molina C.

Transl Res. 2014 Jul;164(1):13-21. doi: 10.1016/j.trsl.2014.03.003. Epub 2014 Mar 13. Review.


Translational implications of the β-cell epigenome in diabetes mellitus.

Johnson JS, Evans-Molina C.

Transl Res. 2015 Jan;165(1):91-101. doi: 10.1016/j.trsl.2014.03.002. Epub 2014 Mar 12. Review.


Established and emerging biomarkers for the prediction of type 1 diabetes: a systematic review.

Watkins RA, Evans-Molina C, Blum JS, DiMeglio LA.

Transl Res. 2014 Aug;164(2):110-21. doi: 10.1016/j.trsl.2014.02.004. Epub 2014 Mar 4. Review.


Shock wave lithotripsy targeting of the kidney and pancreas does not increase the severity of metabolic syndrome in a porcine model.

Handa RK, Evan AP, Connors BA, Johnson CD, Liu Z, Alloosh M, Sturek M, Evans-Molina C, Mandeville JA, Gnessin E, Lingeman JE.

J Urol. 2014 Oct;192(4):1257-65. doi: 10.1016/j.juro.2014.03.035. Epub 2014 Mar 18.


Human adipose-derived stromal/stem cells protect against STZ-induced hyperglycemia: analysis of hASC-derived paracrine effectors.

Kono TM, Sims EK, Moss DR, Yamamoto W, Ahn G, Diamond J, Tong X, Day KH, Territo PR, Hanenberg H, Traktuev DO, March KL, Evans-Molina C.

Stem Cells. 2014 Jul;32(7):1831-42. doi: 10.1002/stem.1676.


A case of calciphylaxis in a patient with hypoparathyroidism and normal renal function.

Erdel BL, Juneja R, Evans-Molina C.

Endocr Pract. 2014 Jun;20(6):e102-5. doi: 10.4158/EP13509.CR.


Regenerative therapeutic potential of adipose stromal cells in early stage diabetic retinopathy.

Rajashekhar G, Ramadan A, Abburi C, Callaghan B, Traktuev DO, Evans-Molina C, Maturi R, Harris A, Kern TS, March KL.

PLoS One. 2014 Jan 9;9(1):e84671. doi: 10.1371/journal.pone.0084671. eCollection 2014.


Urinary biomarkers for the early diagnosis of retinopathy and nephropathy in type 1 diabetes mellitus: a "steady stream" of information using proteomics.

Sims EK, Evans-Molina C.

Transl Res. 2014 Mar;163(3):183-7. doi: 10.1016/j.trsl.2013.11.013. Epub 2013 Nov 28. No abstract available.


Divergent compensatory responses to high-fat diet between C57BL6/J and C57BLKS/J inbred mouse strains.

Sims EK, Hatanaka M, Morris DL, Tersey SA, Kono T, Chaudry ZZ, Day KH, Moss DR, Stull ND, Mirmira RG, Evans-Molina C.

Am J Physiol Endocrinol Metab. 2013 Dec;305(12):E1495-511. doi: 10.1152/ajpendo.00366.2013. Epub 2013 Oct 29.


Lost in translation: endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus.

Evans-Molina C, Hatanaka M, Mirmira RG.

Diabetes Obes Metab. 2013 Sep;15 Suppl 3:159-69. doi: 10.1111/dom.12163. Review.


High glucose represses β-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: involvement of peroxisome proliferator-activated receptor γ signaling.

So WY, Cheng Q, Chen L, Evans-Molina C, Xu A, Lam KS, Leung PS.

Diabetes. 2013 Nov;62(11):3751-9. doi: 10.2337/db13-0645. Epub 2013 Jul 29.


Streptozotocin is equally diabetogenic whether administered to fed or fasted mice.

Chaudhry ZZ, Morris DL, Moss DR, Sims EK, Chiong Y, Kono T, Evans-Molina C.

Lab Anim. 2013 Oct;47(4):257-65. doi: 10.1177/0023677213489548. Epub 2013 Jun 10.


Achieving "PeaK-A" insulin secretion.

Evans-Molina C, Mirmira RG.

Diabetes. 2013 May;62(5):1389-90. doi: 10.2337/db13-0196. No abstract available.

Supplemental Content

Loading ...
Support Center