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Genome and epigenome wide studies of neurological protein biomarkers in the Lothian Birth Cohort 1936.

Hillary RF, McCartney DL, Harris SE, Stevenson AJ, Seeboth A, Zhang Q, Liewald DC, Evans KL, Ritchie CW, Tucker-Drob EM, Wray NR, McRae AF, Visscher PM, Deary IJ, Marioni RE.

Nat Commun. 2019 Jul 18;10(1):3160. doi: 10.1038/s41467-019-11177-x.


Urban meadows as an alternative to short mown grassland: effects of composition and height on biodiversity.

Norton BA, Bending GD, Clark R, Corstanje R, Dunnett N, Evans KL, Grafius DR, Gravestock E, Grice SM, Harris JA, Hilton S, Hoyle H, Lim E, Mercer TG, Pawlett M, Pescott OL, Richards JP, Southon GE, Warren PH.

Ecol Appl. 2019 Jun 7:e01946. doi: 10.1002/eap.1946. [Epub ahead of print]


Correction: GWAS on family history of Alzheimer's disease.

Marioni RE, Harris SE, Zhang Q, McRae AF, Hagenaars SP, Hill WD, Davies G, Ritchie CW, Gale CR, Starr JM, Goate AM, Porteous DJ, Yang J, Evans KL, Deary IJ, Wray NR, Visscher PM.

Transl Psychiatry. 2019 Jun 6;9(1):161. doi: 10.1038/s41398-019-0498-2.


Genetics of heart rate in heart failure patients (GenHRate).

Evans KL, Wirtz HS, Li J, She R, Maya J, Gui H, Hamer A, Depre C, Lanfear DE.

Hum Genomics. 2019 May 21;13(1):22. doi: 10.1186/s40246-019-0206-6.


Publisher Correction: Parent of origin genetic effects on methylation in humans are common and influence complex trait variation.

Zeng Y, Amador C, Xia C, Marioni R, Sproul D, Walker RM, Morris SW, Bretherick A, Canela-Xandri O, Boutin TS, Clark DW, Campbell A, Rawlik K, Hayward C, Nagy R, Tenesa A, Porteous DJ, Wilson JF, Deary IJ, Evans KL, McIntosh AM, Navarro P, Haley CS.

Nat Commun. 2019 May 1;10(1):2069. doi: 10.1038/s41467-019-10155-7.


Assessment of dried blood spots for DNA methylation profiling.

Walker RM, MacGillivray L, McCafferty S, Wrobel N, Murphy L, Kerr SM, Morris SW, Campbell A, McIntosh AM, Porteous DJ, Evans KL.

Wellcome Open Res. 2019 Mar 6;4:44. doi: 10.12688/wellcomeopenres.15136.1. eCollection 2019.


Identification of novel differentially methylated sites with potential as clinical predictors of impaired respiratory function and COPD.

Bermingham ML, Walker RM, Marioni RE, Morris SW, Rawlik K, Zeng Y, Campbell A, Redmond P, Whalley HC, Adams MJ, Hayward C, Deary IJ, Porteous DJ, McIntosh AM, Evans KL.

EBioMedicine. 2019 May;43:576-586. doi: 10.1016/j.ebiom.2019.03.072. Epub 2019 Mar 29.


Parent of origin genetic effects on methylation in humans are common and influence complex trait variation.

Zeng Y, Amador C, Xia C, Marioni R, Sproul D, Walker RM, Morris SW, Bretherick A, Canela-Xandri O, Boutin TS, Clark DW, Campbell A, Rawlik K, Hayward C, Nagy R, Tenesa A, Porteous DJ, Wilson JF, Deary IJ, Evans KL, McIntosh AM, Navarro P, Haley CS.

Nat Commun. 2019 Mar 27;10(1):1383. doi: 10.1038/s41467-019-09301-y. Erratum in: Nat Commun. 2019 May 1;10(1):2069.


An epigenetic score for BMI based on DNA methylation correlates with poor physical health and major disease in the Lothian Birth Cohort.

Hamilton OKL, Zhang Q, McRae AF, Walker RM, Morris SW, Redmond P, Campbell A, Murray AD, Porteous DJ, Evans KL, McIntosh AM, Deary IJ, Marioni RE.

Int J Obes (Lond). 2019 Mar 6. doi: 10.1038/s41366-018-0262-3. [Epub ahead of print]


Epigenetic signatures of starting and stopping smoking.

McCartney DL, Stevenson AJ, Hillary RF, Walker RM, Bermingham ML, Morris SW, Clarke TK, Campbell A, Murray AD, Whalley HC, Porteous DJ, Visscher PM, McIntosh AM, Evans KL, Deary IJ, Marioni RE.

EBioMedicine. 2018 Nov;37:214-220. doi: 10.1016/j.ebiom.2018.10.051. Epub 2018 Oct 30.


Epigenetic prediction of complex traits and death.

McCartney DL, Hillary RF, Stevenson AJ, Ritchie SJ, Walker RM, Zhang Q, Morris SW, Bermingham ML, Campbell A, Murray AD, Whalley HC, Gale CR, Porteous DJ, Haley CS, McRae AF, Wray NR, Visscher PM, McIntosh AM, Evans KL, Deary IJ, Marioni RE.

Genome Biol. 2018 Sep 27;19(1):136. doi: 10.1186/s13059-018-1514-1.


DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness.

Malavasi ELV, Economides KD, Grünewald E, Makedonopoulou P, Gautier P, Mackie S, Murphy LC, Murdoch H, Crummie D, Ogawa F, McCartney DL, O'Sullivan ST, Burr K, Torrance HS, Phillips J, Bonneau M, Anderson SM, Perry P, Pearson M, Constantinides C, Davidson-Smith H, Kabiri M, Duff B, Johnstone M, Polites HG, Lawrie SM, Blackwood DH, Semple CA, Evans KL, Didier M, Chandran S, McIntosh AM, Price DJ, Houslay MD, Porteous DJ, Millar JK.

Transl Psychiatry. 2018 Sep 6;8(1):184. doi: 10.1038/s41398-018-0228-1.


Investigating the relationship between DNA methylation age acceleration and risk factors for Alzheimer's disease.

McCartney DL, Stevenson AJ, Walker RM, Gibson J, Morris SW, Campbell A, Murray AD, Whalley HC, Porteous DJ, McIntosh AM, Evans KL, Deary IJ, Marioni RE.

Alzheimers Dement (Amst). 2018 Jun 21;10:429-437. doi: 10.1016/j.dadm.2018.05.006. eCollection 2018.


Quantifying carbon stocks in shifting cultivation landscapes under divergent management scenarios relevant to REDD.

Borah JR, Evans KL, Edwards DP.

Ecol Appl. 2018 Sep;28(6):1581-1593. doi: 10.1002/eap.1764. Epub 2018 Jul 25.


The Effects of Arbuscular Mycorrhizal Fungal Colonisation on Nutrient Status, Growth, Productivity, and Canker Resistance of Apple (Malus pumila).

Berdeni D, Cotton TEA, Daniell TJ, Bidartondo MI, Cameron DD, Evans KL.

Front Microbiol. 2018 Jul 3;9:1461. doi: 10.3389/fmicb.2018.01461. eCollection 2018.


DNA Methylation Signatures of Depressive Symptoms in Middle-aged and Elderly Persons: Meta-analysis of Multiethnic Epigenome-wide Studies.

Story Jovanova O, Nedeljkovic I, Spieler D, Walker RM, Liu C, Luciano M, Bressler J, Brody J, Drake AJ, Evans KL, Gondalia R, Kunze S, Kuhnel B, Lahti J, Lemaitre RN, Marioni RE, Swenson B, Himali JJ, Wu H, Li Y, McRae AF, Russ TC, Stewart J, Wang Z, Zhang G, Ladwig KH, Uitterlinden AG, Guo X, Peters A, Räikkönen K, Starr JM, Waldenberger M, Wray NR, Whitsel EA, Sotoodehnia N, Seshadri S, Porteous DJ, van Meurs J, Mosley TH, McIntosh AM, Mendelson MM, Levy D, Hou L, Eriksson JG, Fornage M, Deary IJ, Baccarelli A, Tiemeier H, Amin N.

JAMA Psychiatry. 2018 Sep 1;75(9):949-959. doi: 10.1001/jamapsychiatry.2018.1725.


DNA sequence-level analyses reveal potential phenotypic modifiers in a large family with psychiatric disorders.

Ryan NM, Lihm J, Kramer M, McCarthy S, Morris SW, Arnau-Soler A, Davies G, Duff B, Ghiban E, Hayward C, Deary IJ, Blackwood DHR, Lawrie SM, McIntosh AM, Evans KL, Porteous DJ, McCombie WR, Thomson PA.

Mol Psychiatry. 2018 Dec;23(12):2254-2265. doi: 10.1038/s41380-018-0087-4. Epub 2018 Jun 7.


GWAS on family history of Alzheimer's disease.

Marioni RE, Harris SE, Zhang Q, McRae AF, Hagenaars SP, Hill WD, Davies G, Ritchie CW, Gale CR, Starr JM, Goate AM, Porteous DJ, Yang J, Evans KL, Deary IJ, Wray NR, Visscher PM.

Transl Psychiatry. 2018 May 18;8(1):99. doi: 10.1038/s41398-018-0150-6. Erratum in: Transl Psychiatry. 2019 Jun 6;9(1):161.


Tritrophic phenological match-mismatch in space and time.

Burgess MD, Smith KW, Evans KL, Leech D, Pearce-Higgins JW, Branston CJ, Briggs K, Clark JR, du Feu CR, Lewthwaite K, Nager RG, Sheldon BC, Smith JA, Whytock RC, Willis SG, Phillimore AB.

Nat Ecol Evol. 2018 Jun;2(6):970-975. doi: 10.1038/s41559-018-0543-1. Epub 2018 Apr 23.


Impact of urbanization on abundance and phenology of caterpillars and consequences for breeding in an insectivorous bird.

Seress G, Hammer T, Bókony V, Vincze E, Preiszner B, Pipoly I, Sinkovics C, Evans KL, Liker A.

Ecol Appl. 2018 Jul;28(5):1143-1156. doi: 10.1002/eap.1730. Epub 2018 Jun 1.


Altered DNA methylation associated with a translocation linked to major mental illness.

McCartney DL, Walker RM, Morris SW, Anderson SM, Duff BJ, Marioni RE, Millar JK, McCarthy SE, Ryan NM, Lawrie SM, Watson AR, Blackwood DHR, Thomson PA, McIntosh AM, McCombie WR, Porteous DJ, Evans KL.

NPJ Schizophr. 2018 Mar 19;4(1):5. doi: 10.1038/s41537-018-0047-7.


The impact of within and between role experiences on role balance outcomes for working Sandwich Generation Women.

Evans KL, Millsteed J, Richmond JE, Falkmer M, Falkmer T, Girdler SJ.

Scand J Occup Ther. 2019 Apr;26(3):184-193. doi: 10.1080/11038128.2018.1449888. Epub 2018 Mar 15.


PURLs: Does fish oil during pregnancy help prevent asthma in kids?

Neutze D, Evans KL, Koenig M, Castelli G, Mounsey A.

J Fam Pract. 2018 Feb;67(2):100-102.


Genome-wide haplotype-based association analysis of major depressive disorder in Generation Scotland and UK Biobank.

Howard DM, Hall LS, Hafferty JD, Zeng Y, Adams MJ, Clarke TK, Porteous DJ, Nagy R, Hayward C, Smith BH, Murray AD, Ryan NM, Evans KL, Haley CS, Deary IJ, Thomson PA, McIntosh AM.

Transl Psychiatry. 2017 Nov 30;7(11):1263. doi: 10.1038/s41398-017-0010-9.


Identification of a novel locus on chromosome 2q13, which predisposes to clinical vertebral fractures independently of bone density.

Alonso N, Estrada K, Albagha OME, Herrera L, Reppe S, Olstad OK, Gautvik KM, Ryan NM, Evans KL, Nielson CM, Hsu YH, Kiel DP, Markozannes G, Ntzani EE, Evangelou E, Feenstra B, Liu X, Melbye M, Masi L, Brandi ML, Riches P, Daroszewska A, Olmos JM, Valero C, Castillo J, Riancho JA, Husted LB, Langdahl BL, Brown MA, Duncan EL, Kaptoge S, Khaw KT, Usategui-Martín R, Del Pino-Montes J, González-Sarmiento R, Lewis JR, Prince RL, D'Amelio P, García-Giralt N, Nogués X, Mencej-Bedrac S, Marc J, Wolstein O, Eisman JA, Oei L, Medina-Gómez C, Schraut KE, Navarro P, Wilson JF, Davies G, Starr J, Deary I, Tanaka T, Ferrucci L, Gianfrancesco F, Gennari L, Lucas G, Elosua R, Uitterlinden AG, Rivadeneira F, Ralston SH.

Ann Rheum Dis. 2018 Mar;77(3):378-385. doi: 10.1136/annrheumdis-2017-212469. Epub 2017 Nov 23.


Cohort Profile: Stratifying Resilience and Depression Longitudinally (STRADL): a questionnaire follow-up of Generation Scotland: Scottish Family Health Study (GS:SFHS).

Navrady LB, Wolters MK, MacIntyre DJ, Clarke TK, Campbell AI, Murray AD, Evans KL, Seckl J, Haley C, Milburn K, Wardlaw JM, Porteous DJ, Deary IJ, McIntosh AM.

Int J Epidemiol. 2018 Feb 1;47(1):13-14g. doi: 10.1093/ije/dyx115. No abstract available.


Haplotype-based association analysis of general cognitive ability in Generation Scotland, the English Longitudinal Study of Ageing, and UK Biobank.

Howard DM, Adams MJ, Clarke TK, Wigmore EM, Zeng Y, Hagenaars SP, Lyall DM, Thomson PA, Evans KL, Porteous DJ, Nagy R, Hayward C, Haley CS, Smith BH, Murray AD, Batty GD, Deary IJ, McIntosh AM.

Wellcome Open Res. 2017 Aug 10;2:61. doi: 10.12688/wellcomeopenres.12171.1. eCollection 2017.


Henry Ford HEART Score Randomized Trial: Rapid Discharge of Patients Evaluated for Possible Myocardial Infarction.

Frisoli TM, Nowak R, Evans KL, Harrison M, Alani M, Varghese S, Rahman M, Noll S, Flannery KR, Michaels A, Tabaku M, Jacobsen G, McCord J.

Circ Cardiovasc Qual Outcomes. 2017 Oct;10(10). pii: e003617. doi: 10.1161/CIRCOUTCOMES.117.003617.


Reduced severity of lumbo-pelvic-hip injuries in professional Rugby Union players following tailored preventative programmes.

Evans KL, Hughes J, Williams MD.

J Sci Med Sport. 2018 Mar;21(3):274-279. doi: 10.1016/j.jsams.2017.07.004. Epub 2017 Jul 12.


Rare disruptive variants in the DISC1 Interactome and Regulome: association with cognitive ability and schizophrenia.

Teng S, Thomson PA, McCarthy S, Kramer M, Muller S, Lihm J, Morris S, Soares DC, Hennah W, Harris S, Camargo LM, Malkov V, McIntosh AM, Millar JK, Blackwood DH, Evans KL, Deary IJ, Porteous DJ, McCombie WR.

Mol Psychiatry. 2018 May;23(5):1270-1277. doi: 10.1038/mp.2017.115. Epub 2017 Jun 20.


'Green' on the ground but not in the air: Pro-environmental attitudes are related to household behaviours but not discretionary air travel.

Alcock I, White MP, Taylor T, Coldwell DF, Gribble MO, Evans KL, Corner A, Vardoulakis S, Fleming LE.

Glob Environ Change. 2017 Jan;42:136-147. doi: 10.1016/j.gloenvcha.2016.11.005. Epub 2017 Jan 17.


Contrasting effects of visiting urban green-space and the countryside on biodiversity knowledge and conservation support.

Coldwell DF, Evans KL.

PLoS One. 2017 Mar 23;12(3):e0174376. doi: 10.1371/journal.pone.0174376. eCollection 2017.


Optimising UK urban road verge contributions to biodiversity and ecosystem services with cost-effective management.

O'Sullivan OS, Holt AR, Warren PH, Evans KL.

J Environ Manage. 2017 Apr 15;191:162-171. doi: 10.1016/j.jenvman.2016.12.062. Epub 2017 Jan 14. Review.


Viewpoints of working sandwich generation women and occupational therapists on role balance strategies.

Evans KL, Girdler SJ, Falkmer T, Richmond JE, Wagman P, Millsteed J, Falkmer M.

Scand J Occup Ther. 2017 Sep;24(5):366-382. doi: 10.1080/11038128.2016.1250814. Epub 2016 Nov 4.


Preliminary assessment of pre-morbid DNA methylation in individuals at high genetic risk of mood disorders.

Walker RM, Sussmann JE, Whalley HC, Ryan NM, Porteous DJ, McIntosh AM, Evans KL.

Bipolar Disord. 2016 Aug;18(5):410-22. doi: 10.1111/bdi.12415. Epub 2016 Jul 21.


Identification of polymorphic and off-target probe binding sites on the Illumina Infinium MethylationEPIC BeadChip.

McCartney DL, Walker RM, Morris SW, McIntosh AM, Porteous DJ, Evans KL.

Genom Data. 2016 May 26;9:22-4. doi: 10.1016/j.gdata.2016.05.012. eCollection 2016 Sep.


Working Sandwich Generation Women Utilize Strategies within and between Roles to Achieve Role Balance.

Evans KL, Millsteed J, Richmond JE, Falkmer M, Falkmer T, Girdler SJ.

PLoS One. 2016 Jun 15;11(6):e0157469. doi: 10.1371/journal.pone.0157469. eCollection 2016.


DNA methylation in a Scottish family multiply affected by bipolar disorder and major depressive disorder.

Walker RM, Christoforou AN, McCartney DL, Morris SW, Kennedy NA, Morten P, Anderson SM, Torrance HS, Macdonald A, Sussmann JE, Whalley HC, Blackwood DH, McIntosh AM, Porteous DJ, Evans KL.

Clin Epigenetics. 2016 Jan 20;8:5. doi: 10.1186/s13148-016-0171-z. eCollection 2016.


Sex-dependent effects on tasks assessing reinforcement learning and interference inhibition.

Evans KL, Hampson E.

Front Psychol. 2015 Jul 22;6:1044. doi: 10.3389/fpsyg.2015.01044. eCollection 2015.


Working memory in pregnant women: Relation to estrogen and antepartum depression.

Hampson E, Phillips SD, Duff-Canning SJ, Evans KL, Merrill M, Pinsonneault JK, Sadée W, Soares CN, Steiner M.

Horm Behav. 2015 Aug;74:218-27. doi: 10.1016/j.yhbeh.2015.07.006. Epub 2015 Jul 15.


A global assessment of the social and conservation outcomes of protected areas.

Oldekop JA, Holmes G, Harris WE, Evans KL.

Conserv Biol. 2016 Feb;30(1):133-41. doi: 10.1111/cobi.12568. Epub 2015 Sep 22.


Regional and physician specialty-associated variations in the medical management of atherosclerotic renal-artery stenosis.

Folt DA, Evans KL, Brahmandam S, He W, Brewster PS, Yu S, Murphy TP, Cutlip DE, Dworkin LD, Jamerson K, Henrich W, Kalra PA, Tobe S, Thomson K, Holden A, Rayner BL, Grinfeld L, Haller ST, Cooper CJ.

J Am Soc Hypertens. 2015 Jun;9(6):443-52. doi: 10.1016/j.jash.2015.03.007. Epub 2015 Mar 28.


Preliminary investigation of miRNA expression in individuals at high familial risk of bipolar disorder.

Walker RM, Rybka J, Anderson SM, Torrance HS, Boxall R, Sussmann JE, Porteous DJ, McIntosh AM, Evans KL.

J Psychiatr Res. 2015 Mar;62:48-55. doi: 10.1016/j.jpsychires.2015.01.006. Epub 2015 Jan 22.


Sex differences on prefrontally-dependent cognitive tasks.

Evans KL, Hampson E.

Brain Cogn. 2015 Feb;93:42-53. doi: 10.1016/j.bandc.2014.11.006. Epub 2014 Dec 16.


SuRFing the genomics wave: an R package for prioritising SNPs by functionality.

Ryan NM, Morris SW, Porteous DJ, Taylor MS, Evans KL.

Genome Med. 2014 Oct 14;6(10):79. doi: 10.1186/s13073-014-0079-1. eCollection 2014.


Relative roles of grey squirrels, supplementary feeding, and habitat in shaping urban bird assemblages.

Bonnington C, Gaston KJ, Evans KL.

PLoS One. 2014 Oct 22;9(10):e109397. doi: 10.1371/journal.pone.0109397. eCollection 2014.


Endovascular versus medical therapy for atherosclerotic renovascular disease.

Yu MS, Folt DA, Drummond CA, Haller ST, Cooper EL, Brewster P, Evans KL, Cooper CJ.

Curr Atheroscler Rep. 2014 Dec;16(12):459. doi: 10.1007/s11883-014-0459-4. Review.


Donor-recipient allele-level HLA matching of unrelated cord blood units reveals high degrees of mismatch and alters graft selection.

Dahi PB, Ponce DM, Devlin S, Evans KL, Lubin M, Gonzales AM, Byam C, Sideroff M, Wells D, Giralt S, Kernan NA, Scaradavou A, Barker JN.

Bone Marrow Transplant. 2014 Sep;49(9):1184-6. doi: 10.1038/bmt.2014.135. Epub 2014 Jul 7.


Expression of DISC1-interactome members correlates with cognitive phenotypes related to schizophrenia.

Rampino A, Walker RM, Torrance HS, Anderson SM, Fazio L, Di Giorgio A, Taurisano P, Gelao B, Romano R, Masellis R, Ursini G, Caforio G, Blasi G, Millar JK, Porteous DJ, Thomson PA, Bertolino A, Evans KL.

PLoS One. 2014 Jun 18;9(6):e99892. doi: 10.1371/journal.pone.0099892. eCollection 2014.


Use of renin-angiotensin inhibitors in people with renal artery stenosis.

Evans KL, Tuttle KR, Folt DA, Dawson T, Haller ST, Brewster PS, He W, Jamerson K, Dworkin LD, Cutlip DE, Murphy TP, D'Agostino RB Sr, Henrich W, Cooper CJ.

Clin J Am Soc Nephrol. 2014 Jul;9(7):1199-206. doi: 10.2215/CJN.11611113. Epub 2014 Jun 5.

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