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Items: 30


Using Small Peptide Segments of Amyloid-β and Humanin to Examine their Physical Interactions.

Heyl DL, Iwaniec B, Esckilsen D, Price D, Guttikonda P, Cooper J, Lombardi J, Milletti M, Evans HG.

Protein Pept Lett. 2019;26(7):502-511. doi: 10.2174/0929866526666190405122117.


Interaction of Insulin-Like Growth Factor-Binding Protein 3 With Hyaluronan and Its Regulation by Humanin and CD44.

Muterspaugh R, Price D, Esckilsen D, McEachern S, Guthrie J, Heyl D, Evans HG.

Biochemistry. 2018 Oct 2;57(39):5726-5737. doi: 10.1021/acs.biochem.8b00635. Epub 2018 Sep 17.


D-Amino Acid Analogues of the Antimicrobial Peptide CDT Exhibit Anti- Cancer Properties in A549, a Human Lung Adenocarcinoma Cell Line.

Evans HG, Guthrie JW, Jujjavarapu M, Hendrickson N, Eitel A, Park Y, Garvey J, Newman R, Esckilsen D, Heyl DL.

Protein Pept Lett. 2017;24(7):590-598. doi: 10.2174/0929866524666170621093647.


Interleukin-10 and prostaglandin E2 have complementary but distinct suppressive effects on Toll-like receptor-mediated dendritic cell activation in ovarian carcinoma.

Brencicova E, Jagger AL, Evans HG, Georgouli M, Laios A, Attard Montalto S, Mehra G, Spencer J, Ahmed AA, Raju-Kankipati S, Taams LS, Diebold SS.

PLoS One. 2017 Apr 14;12(4):e0175712. doi: 10.1371/journal.pone.0175712. eCollection 2017.


TNF Blockade Maintains an IL-10+ Phenotype in Human Effector CD4+ and CD8+ T Cells.

Roberts CA, Durham LE, Fleskens V, Evans HG, Taams LS.

Front Immunol. 2017 Feb 15;8:157. doi: 10.3389/fimmu.2017.00157. eCollection 2017.


Resolving TYK2 locus genotype-to-phenotype differences in autoimmunity.

Dendrou CA, Cortes A, Shipman L, Evans HG, Attfield KE, Jostins L, Barber T, Kaur G, Kuttikkatte SB, Leach OA, Desel C, Faergeman SL, Cheeseman J, Neville MJ, Sawcer S, Compston A, Johnson AR, Everett C, Bell JI, Karpe F, Ultsch M, Eigenbrot C, McVean G, Fugger L.

Sci Transl Med. 2016 Nov 2;8(363):363ra149.


Activation of Latent Dihydroorotase from Aquifex aeolicus by Pressure.

Hervé G, Evans HG, Fernado R, Patel C, Hachem F, Evans DR.

J Biol Chem. 2017 Jan 13;292(2):629-637. doi: 10.1074/jbc.M116.739862. Epub 2016 Oct 16.


Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses.

Cheng WC, van Asten SD, Burns LA, Evans HG, Walter GJ, Hashim A, Hughes FJ, Taams LS.

Eur J Immunol. 2016 Sep;46(9):2211-21. doi: 10.1002/eji.201545871. Epub 2016 Aug 1.


Phenotypic, Functional, and Gene Expression Profiling of Peripheral CD45RA+ and CD45RO+ CD4+CD25+CD127(low) Treg Cells in Patients With Chronic Rheumatoid Arthritis.

Walter GJ, Fleskens V, Frederiksen KS, Rajasekhar M, Menon B, Gerwien JG, Evans HG, Taams LS.

Arthritis Rheumatol. 2016 Jan;68(1):103-16. doi: 10.1002/art.39408.


TNF-α blockade induces IL-10 expression in human CD4+ T cells.

Evans HG, Roostalu U, Walter GJ, Gullick NJ, Frederiksen KS, Roberts CA, Sumner J, Baeten DL, Gerwien JG, Cope AP, Geissmann F, Kirkham BW, Taams LS.

Nat Commun. 2014;5:3199. doi: 10.1038/ncomms4199.


Interleukin-17+CD8+ T cells are enriched in the joints of patients with psoriatic arthritis and correlate with disease activity and joint damage progression.

Menon B, Gullick NJ, Walter GJ, Rajasekhar M, Garrood T, Evans HG, Taams LS, Kirkham BW.

Arthritis Rheumatol. 2014 May;66(5):1272-81. doi: 10.1002/art.38376.


Intersubunit communication in the dihydroorotase-aspartate transcarbamoylase complex of Aquifex aeolicus.

Evans HG, Fernando R, Vaishnav A, Kotichukkala M, Heyl D, Hachem F, Brunzelle JS, Edwards BF, Evans DR.

Protein Sci. 2014 Jan;23(1):100-9. doi: 10.1002/pro.2396.


The mononuclear metal center of type-I dihydroorotase from Aquifex aeolicus.

Edwards BF, Fernando R, Martin PD, Grimley E, Cordes M, Vaishnav A, Brunzelle JS, Evans HG, Evans DR.

BMC Biochem. 2013 Dec 9;14:36. doi: 10.1186/1471-2091-14-36.


Thymosin β4-sulfoxide attenuates inflammatory cell infiltration and promotes cardiac wound healing.

Evans MA, Smart N, Dubé KN, Bollini S, Clark JE, Evans HG, Taams LS, Richardson R, Lévesque M, Martin P, Mills K, Riegler J, Price AN, Lythgoe MF, Riley PR.

Nat Commun. 2013;4:2081. doi: 10.1038/ncomms3081.


Enhanced and persistent levels of interleukin (IL)-17⁺ CD4⁺ T cells and serum IL-17 in patients with early inflammatory arthritis.

Gullick NJ, Abozaid HS, Jayaraj DM, Evans HG, Scott DL, Choy EH, Taams LS.

Clin Exp Immunol. 2013 Nov;174(2):292-301. doi: 10.1111/cei.12167.


Interaction with activated monocytes enhances cytokine expression and suppressive activity of human CD4+CD45ro+CD25+CD127(low) regulatory T cells.

Walter GJ, Evans HG, Menon B, Gullick NJ, Kirkham BW, Cope AP, Geissmann F, Taams LS.

Arthritis Rheum. 2013 Mar;65(3):627-38. doi: 10.1002/art.37832.


FLASH knockdown sensitizes cells to Fas-mediated apoptosis via down-regulation of the anti-apoptotic proteins, MCL-1 and Cflip short.

Chen S, Evans HG, Evans DR.

PLoS One. 2012;7(3):e32971. doi: 10.1371/journal.pone.0032971. Epub 2012 Mar 9.


FAS/FAS-L dependent killing of activated human monocytes and macrophages by CD4+CD25- responder T cells, but not CD4+CD25+ regulatory T cells.

Jagger AL, Evans HG, Walter GJ, Gullick NJ, Menon B, Ballantine LE, Gracie A, Magerus-Chatinet A, Tiemessen MM, Geissmann F, Rieux-Laucat F, Taams LS.

J Autoimmun. 2012 Feb;38(1):29-38. doi: 10.1016/j.jaut.2011.11.015. Epub 2011 Dec 24.


FAM129B/MINERVA, a novel adherens junction-associated protein, suppresses apoptosis in HeLa cells.

Chen S, Evans HG, Evans DR.

J Biol Chem. 2011 Mar 25;286(12):10201-9. doi: 10.1074/jbc.M110.175273. Epub 2010 Dec 9.


Linking power Doppler ultrasound to the presence of th17 cells in the rheumatoid arthritis joint.

Gullick NJ, Evans HG, Church LD, Jayaraj DM, Filer A, Kirkham BW, Taams LS.

PLoS One. 2010 Sep 1;5(9). pii: e12516. doi: 10.1371/journal.pone.0012516.


In vivo activated monocytes from the site of inflammation in humans specifically promote Th17 responses.

Evans HG, Gullick NJ, Kelly S, Pitzalis C, Lord GM, Kirkham BW, Taams LS.

Proc Natl Acad Sci U S A. 2009 Apr 14;106(15):6232-7. doi: 10.1073/pnas.0808144106. Epub 2009 Mar 26.


The sole serine/threonine protein kinase and its cognate phosphatase from Aquifex aeolicus targets pyrimidine biosynthesis.

Purcarea C, Fernando R, Evans HG, Evans DR.

Mol Cell Biochem. 2008 Apr;311(1-2):199-213. doi: 10.1007/s11010-008-9710-z. Epub 2008 Feb 13.


CD4+CD25+Foxp3+ regulatory T cells induce alternative activation of human monocytes/macrophages.

Tiemessen MM, Jagger AL, Evans HG, van Herwijnen MJ, John S, Taams LS.

Proc Natl Acad Sci U S A. 2007 Dec 4;104(49):19446-51. Epub 2007 Nov 27.


Optimal induction of T helper 17 cells in humans requires T cell receptor ligation in the context of Toll-like receptor-activated monocytes.

Evans HG, Suddason T, Jackson I, Taams LS, Lord GM.

Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17034-9. Epub 2007 Oct 17.


Modulation of myocardial relaxation by basal release of endothelin from endocardial endothelium.

Evans HG, Lewis MJ, Shah AM.

Cardiovasc Res. 1994 Nov;28(11):1694-9.


Interleukin-1 beta modulates myocardial contraction via dexamethasone sensitive production of nitric oxide.

Evans HG, Lewis MJ, Shah AM.

Cardiovasc Res. 1993 Aug;27(8):1486-90.


Human red blood cells inhibit endothelium-derived relaxing factor (EDRF) activity.

Evans HG, Ryley HC, Hallett I, Lewis MJ.

Eur J Pharmacol. 1989 Apr 25;163(2-3):361-4.


Release of endothelium-derived relaxing factor is inhibited by 8-bromo-cyclic guanosine monophosphate.

Evans HG, Smith JA, Lewis MJ.

J Cardiovasc Pharmacol. 1988 Dec;12(6):672-7.


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