Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 105

1.

A lipid site shapes the agonist response of a pentameric ligand-gated ion channel.

Hénault CM, Govaerts C, Spurny R, Brams M, Estrada-Mondragon A, Lynch J, Bertrand D, Pardon E, Evans GL, Woods K, Elberson BW, Cuello LG, Brannigan G, Nury H, Steyaert J, Baenziger JE, Ulens C.

Nat Chem Biol. 2019 Oct 7. doi: 10.1038/s41589-019-0369-4. [Epub ahead of print]

PMID:
31591563
2.

Datasets, processing and refinement details for Mtb-AnPRT: inhibitor structures with various space groups.

Evans GL, Furkert DP, Abermil N, Kundu P, de Lange KM, Parker EJ, Brimble MA, Baker EN, Lott JS.

Data Brief. 2017 Oct 31;15:1019-1029. doi: 10.1016/j.dib.2017.10.051. eCollection 2017 Dec.

3.

Anthranilate phosphoribosyltransferase: Binding determinants for 5'-phospho-alpha-d-ribosyl-1'-pyrophosphate (PRPP) and the implications for inhibitor design.

Evans GL, Furkert DP, Abermil N, Kundu P, de Lange KM, Parker EJ, Brimble MA, Baker EN, Lott JS.

Biochim Biophys Acta Proteins Proteom. 2018 Feb;1866(2):264-274. doi: 10.1016/j.bbapap.2017.08.018. Epub 2017 Aug 26.

PMID:
28844746
4.

Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding.

Anandan A, Evans GL, Condic-Jurkic K, O'Mara ML, John CM, Phillips NJ, Jarvis GA, Wills SS, Stubbs KA, Moraes I, Kahler CM, Vrielink A.

Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2218-2223. doi: 10.1073/pnas.1612927114. Epub 2017 Feb 13.

5.

17α-Estradiol Alleviates Age-related Metabolic and Inflammatory Dysfunction in Male Mice Without Inducing Feminization.

Stout MB, Steyn FJ, Jurczak MJ, Camporez JG, Zhu Y, Hawse JR, Jurk D, Palmer AK, Xu M, Pirtskhalava T, Evans GL, de Souza Santos R, Frank AP, White TA, Monroe DG, Singh RJ, Casaclang-Verzosa G, Miller JD, Clegg DJ, LeBrasseur NK, von Zglinicki T, Shulman GI, Tchkonia T, Kirkland JL.

J Gerontol A Biol Sci Med Sci. 2017 Jan;72(1):3-15. Epub 2016 Jan 24.

6.

Structure and inhibition of subunit I of the anthranilate synthase complex of Mycobacterium tuberculosis and expression of the active complex.

Bashiri G, Johnston JM, Evans GL, Bulloch EM, Goldstone DC, Jirgis EN, Kleinboelting S, Castell A, Ramsay RJ, Manos-Turvey A, Payne RJ, Lott JS, Baker EN.

Acta Crystallogr D Biol Crystallogr. 2015 Nov;71(Pt 11):2297-308. doi: 10.1107/S1399004715017216. Epub 2015 Oct 31.

PMID:
26527146
7.

Structures of Mycobacterium tuberculosis Anthranilate Phosphoribosyltransferase Variants Reveal the Conformational Changes That Facilitate Delivery of the Substrate to the Active Site.

Cookson TV, Evans GL, Castell A, Baker EN, Lott JS, Parker EJ.

Biochemistry. 2015 Oct 6;54(39):6082-92. doi: 10.1021/acs.biochem.5b00612.

PMID:
26356348
8.

Anion homeostasis is important for non-lytic release of BK polyomavirus from infected cells.

Evans GL, Caller LG, Foster V, Crump CM.

Open Biol. 2015 Aug;5(8). pii: 150041. doi: 10.1098/rsob.150041.

9.

Corrigendum: Repurposing the Chemical Scaffold of the Anti-Arthritic Drug Lobenzarit to Target Tryptophan Biosynthesis in Mycobacterium tuberculosis.

Evans GL, Gamage SA, Bulloch EM, Baker EN, Denny WA, Lott JS.

Chembiochem. 2015 Mar 23;16(5):706. doi: 10.1002/cbic.201500098. Epub 2015 Mar 11. No abstract available.

PMID:
26177917
10.

A covalent adduct of MbtN, an acyl-ACP dehydrogenase from Mycobacterium tuberculosis, reveals an unusual acyl-binding pocket.

Chai AF, Bulloch EM, Evans GL, Lott JS, Baker EN, Johnston JM.

Acta Crystallogr D Biol Crystallogr. 2015 Apr;71(Pt 4):862-72. doi: 10.1107/S1399004715001650. Epub 2015 Mar 26.

PMID:
25849397
11.

Mental time travel in dysphoria: Differences in the content and subjective experience of past and future episodes.

Anderson RJ, Evans GL.

Conscious Cogn. 2015 Dec;37:237-48. doi: 10.1016/j.concog.2014.05.006. Epub 2014 Jul 25.

PMID:
25066660
12.

Alternative substrates reveal catalytic cycle and key binding events in the reaction catalysed by anthranilate phosphoribosyltransferase from Mycobacterium tuberculosis.

Cookson TV, Castell A, Bulloch EM, Evans GL, Short FL, Baker EN, Lott JS, Parker EJ.

Biochem J. 2014 Jul 1;461(1):87-98. doi: 10.1042/BJ20140209.

PMID:
24712732
13.

Repurposing the chemical scaffold of the anti-arthritic drug Lobenzarit to target tryptophan biosynthesis in Mycobacterium tuberculosis.

Evans GL, Gamage SA, Bulloch EM, Baker EN, Denny WA, Lott JS.

Chembiochem. 2014 Apr 14;15(6):852-64. doi: 10.1002/cbic.201300628. Epub 2014 Mar 12. Erratum in: Chembiochem. 2015 Mar 23;16(5):706. Chembiochem. 2015 Mar 23;16(5):706.

PMID:
24623674
14.

Purification, crystallization and preliminary X-ray studies of MbtN (Rv1346) from Mycobacterium tuberculosis.

Chai AF, Johnston JM, Bunker RD, Bulloch EM, Evans GL, Lott JS, Baker EN.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Dec;69(Pt 12):1354-6. doi: 10.1107/S1744309113027000. Epub 2013 Nov 28.

15.

The substrate capture mechanism of Mycobacterium tuberculosis anthranilate phosphoribosyltransferase provides a mode for inhibition.

Castell A, Short FL, Evans GL, Cookson TV, Bulloch EM, Joseph DD, Lee CE, Parker EJ, Baker EN, Lott JS.

Biochemistry. 2013 Mar 12;52(10):1776-87. doi: 10.1021/bi301387m. Epub 2013 Feb 28.

PMID:
23363292
16.

Visualisation of direct interaction of MDA5 and the dsRNA replicative intermediate form of positive strand RNA viruses.

Triantafilou K, Vakakis E, Kar S, Richer E, Evans GL, Triantafilou M.

J Cell Sci. 2012 Oct 15;125(Pt 20):4761-9. doi: 10.1242/jcs.103887. Epub 2012 Jul 13.

17.

Implications of binding mode and active site flexibility for inhibitor potency against the salicylate synthase from Mycobacterium tuberculosis.

Chi G, Manos-Turvey A, O'Connor PD, Johnston JM, Evans GL, Baker EN, Payne RJ, Lott JS, Bulloch EM.

Biochemistry. 2012 Jun 19;51(24):4868-79. doi: 10.1021/bi3002067. Epub 2012 Jun 7.

PMID:
22607697
18.

Induction of fracture repair by mesenchymal cells derived from human embryonic stem cells or bone marrow.

Undale A, Fraser D, Hefferan T, Kopher RA, Herrick J, Evans GL, Li X, Kakar S, Hayes M, Atkinson E, Yaszemski MJ, Kaufman DS, Westendorf JJ, Khosla S.

J Orthop Res. 2011 Dec;29(12):1804-11. doi: 10.1002/jor.21480. Epub 2011 Jun 14.

19.

Human rhinovirus recognition in non-immune cells is mediated by Toll-like receptors and MDA-5, which trigger a synergetic pro-inflammatory immune response.

Triantafilou K, Vakakis E, Richer EA, Evans GL, Villiers JP, Triantafilou M.

Virulence. 2011 Jan-Feb;2(1):22-9. Epub 2011 Jan 1.

20.

Caregiver characteristics and their relationship to health service utilization in minority patients with first episode stroke.

Clark AN, Sander AM, Pappadis MR, Evans GL, Truchen MA, Chiou-Tan FY.

NeuroRehabilitation. 2010;27(1):95-104. doi: 10.3233/NRE-2010-0584.

PMID:
20634604
21.

Implementing recommendations to eliminate disparities in clinical trial research.

Evans GL, Weinberg AD.

J Cancer Educ. 2009;24(2 Suppl):S50-1. doi: 10.1080/08858190903400518. No abstract available.

PMID:
20024826
22.

Severe osteogenesis imperfecta in cyclophilin B-deficient mice.

Choi JW, Sutor SL, Lindquist L, Evans GL, Madden BJ, Bergen HR 3rd, Hefferan TE, Yaszemski MJ, Bram RJ.

PLoS Genet. 2009 Dec;5(12):e1000750. doi: 10.1371/journal.pgen.1000750. Epub 2009 Dec 4.

23.

Determinants of low-fat eating behaviors among midlife African American women.

Evans GL, McNeil LH, Laufman L, Bowman SL.

J Nutr Educ Behav. 2009 Sep-Oct;41(5):327-33. doi: 10.1016/j.jneb.2008.07.006.

PMID:
19717115
24.

Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis.

Kefala G, Evans GL, Griffin MD, Devenish SR, Pearce FG, Perugini MA, Gerrard JA, Weiss MS, Dobson RC.

Biochem J. 2008 Apr 15;411(2):351-60.

PMID:
18062777
25.

Inhibiting dihydrodipicolinate synthase across species: towards specificity for pathogens?

Mitsakos V, Dobson RC, Pearce FG, Devenish SR, Evans GL, Burgess BR, Perugini MA, Gerrard JA, Hutton CA.

Bioorg Med Chem Lett. 2008 Jan 15;18(2):842-4. Epub 2007 Nov 13.

PMID:
18054225
26.
27.

Dose-response effects of intermittent PTH on cancellous bone in hindlimb unloaded rats.

Turner RT, Evans GL, Lotinun S, Lapke PD, Iwaniec UT, Morey-Holton E.

J Bone Miner Res. 2007 Jan;22(1):64-71.

28.

Thermodynamics of the fragile X mental retardation protein RGG box interactions with G quartet forming RNA.

Zanotti KJ, Lackey PE, Evans GL, Mihailescu MR.

Biochemistry. 2006 Jul 11;45(27):8319-30.

PMID:
16819831
29.

Dietary soy protein and isoflavones: minimal beneficial effects on bone and no effect on the reproductive tract of sexually mature ovariectomized Sprague-Dawley rats.

Bahr JM, Nakai M, Rivera A, Walsh J, Evans GL, Lotinun S, Turner RT, Black M, Jeffery EH.

Menopause. 2005 Mar;12(2):165-73.

PMID:
15772564
30.

Deletion of membrane-bound steel factor results in osteopenia in mice.

Lotinun S, Evans GL, Turner RT, Oursler MJ.

J Bone Miner Res. 2005 Apr;20(4):644-52. Epub 2004 Dec 6.

31.

Vitamin E provides protection for bone in mature hindlimb unloaded male rats.

Smith BJ, Lucas EA, Turner RT, Evans GL, Lerner MR, Brackett DJ, Stoecker BJ, Arjmandi BH.

Calcif Tissue Int. 2005 Apr;76(4):272-9. Epub 2004 Mar 8.

PMID:
15742232
32.

TIEG1 null mouse-derived osteoblasts are defective in mineralization and in support of osteoclast differentiation in vitro.

Subramaniam M, Gorny G, Johnsen SA, Monroe DG, Evans GL, Fraser DG, Rickard DJ, Rasmussen K, van Deursen JM, Turner RT, Oursler MJ, Spelsberg TC.

Mol Cell Biol. 2005 Feb;25(3):1191-9.

33.

Continuous parathyroid hormone induces cortical porosity in the rat: effects on bone turnover and mechanical properties.

Lotinun S, Evans GL, Bronk JT, Bolander ME, Wronski TJ, Ritman EL, Turner RT.

J Bone Miner Res. 2004 Jul;19(7):1165-71. Epub 2004 Apr 12.

34.

Effect of gender on bone turnover in adult rats during simulated weightlessness.

Hefferan TE, Evans GL, Lotinun S, Zhang M, Morey-Holton E, Turner RT.

J Appl Physiol (1985). 2003 Nov;95(5):1775-80. Epub 2003 Jul 25.

35.

Dose-response effects of 2-methoxyestradiol on estrogen target tissues in the ovariectomized rat.

Sibonga JD, Lotinun S, Evans GL, Pribluda VS, Green SJ, Turner RT.

Endocrinology. 2003 Mar;144(3):785-92.

PMID:
12586754
36.

Disuse exaggerates the detrimental effects of alcohol on cortical bone.

Hefferan TE, Kennedy AM, Evans GL, Turner RT.

Alcohol Clin Exp Res. 2003 Jan;27(1):111-7.

PMID:
12544015
37.

The effects of chronic alcohol consumption and exercise on the skeleton of adult male rats.

Reed AH, McCarty HL, Evans GL, Turner RT, Westerlind KC.

Alcohol Clin Exp Res. 2002 Aug;26(8):1269-74.

PMID:
12198404
38.
39.

Animal models for osteoporosis.

Turner RT, Maran A, Lotinun S, Hefferan T, Evans GL, Zhang M, Sibonga JD.

Rev Endocr Metab Disord. 2001 Jan;2(1):117-27. Review.

PMID:
11704974
40.

Leptin reduces ovariectomy-induced bone loss in rats.

Burguera B, Hofbauer LC, Thomas T, Gori F, Evans GL, Khosla S, Riggs BL, Turner RT.

Endocrinology. 2001 Aug;142(8):3546-53.

PMID:
11459801
41.

Effects of parathyroid hormone on bone formation in a rat model for chronic alcohol abuse.

Turner RT, Evans GL, Zhang M, Sibonga JD.

Alcohol Clin Exp Res. 2001 May;25(5):667-71.

PMID:
11371715
42.

Moderate alcohol consumption suppresses bone turnover in adult female rats.

Turner RT, Kidder LS, Kennedy A, Evans GL, Sibonga JD.

J Bone Miner Res. 2001 Mar;16(3):589-94.

43.

Aged bone displays an increased responsiveness to low-intensity resistance exercise.

Buhl KM, Jacobs CR, Turner RT, Evans GL, Farrell PA, Donahue HJ.

J Appl Physiol (1985). 2001 Apr;90(4):1359-64.

44.

The catechol estrogen, 4-hydroxyestrone, has tissue-specific estrogen actions.

Westerlind KC, Gibson KJ, Evans GL, Turner RT.

J Endocrinol. 2000 Nov;167(2):281-7.

PMID:
11054642
45.

Effects of spaceflight and simulated weightlessness on longitudinal bone growth.

Sibonga JD, Zhang M, Evans GL, Westerlind KC, Cavolina JM, Morey-Holton E, Turner RT.

Bone. 2000 Oct;27(4):535-40.

PMID:
11033449
46.

2-Methoxyestradiol inhibits longitudinal bone growth in normal female rats.

Turner RT, Evans GL.

Calcif Tissue Int. 2000 Jun;66(6):465-9.

PMID:
10821885
47.

The high-affinity estrogen receptor antagonist ICI 182,780 has no effect on bone growth in young male rats.

Turner RT, Evans GL, Dobnig H.

Calcif Tissue Int. 2000 Jun;66(6):461-4.

PMID:
10821884
48.

Effects of orbital spaceflight on human osteoblastic cell physiology and gene expression.

Harris SA, Zhang M, Kidder LS, Evans GL, Spelsberg TC, Turner RT.

Bone. 2000 Apr;26(4):325-31.

PMID:
10719274
49.

Is resveratrol an estrogen agonist in growing rats?

Turner RT, Evans GL, Zhang M, Maran A, Sibonga JD.

Endocrinology. 1999 Jan;140(1):50-4.

PMID:
9886806
50.

The Role of Medical Conditions and Depression in the Functional Outcome of Stroke Survivors: A Review and Pilot Study.

Evans GL, Whitney FW.

Top Stroke Rehabil. 1998 Fall;5(3):30-50. doi: 10.1310/AP5F-RBDN-G74R-LRUT.

PMID:
26368584

Supplemental Content

Loading ...
Support Center