Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 71

1.

The Requirements for Additional Strength Biowaivers for Immediate Release Solid Oral Dosage Forms in International Pharmaceutical Regulators Programme Participating Regulators and Organisations: Differences and Commonalities.

Crane C, Santos GML, Fernandes EAF, Simon C, Tam A, Triana DG, Potthast H, Kuribayashi R, Okada Y, Myoenzono A, Calderon IO, Rodriguez Z, Jones B, Park SA, Eum SY, Rodrigues C, Van Oudsthoorn J, Nolting A, Walther C, Roost MS, Hung WY, Braddy AC, Garcia-Arieta A.

J Pharm Pharm Sci. 2019;22(1):486-500. doi: 10.18433/jpps30724.

2.

Transient drug-tolerance and permanent drug-resistance rely on the trehalose-catalytic shift in Mycobacterium tuberculosis.

Lee JJ, Lee SK, Song N, Nathan TO, Swarts BM, Eum SY, Ehrt S, Cho SN, Eoh H.

Nat Commun. 2019 Jul 2;10(1):2928. doi: 10.1038/s41467-019-10975-7.

3.

Comparison of immunogenicity and vaccine efficacy between heat-shock proteins, HSP70 and GrpE, in the DnaK operon of Mycobacterium tuberculosis.

Kim WS, Kim JS, Kim HM, Kwon KW, Eum SY, Shin SJ.

Sci Rep. 2018 Sep 26;8(1):14411. doi: 10.1038/s41598-018-32799-z.

4.

Circadian Disruption Changes Gut Microbiome Taxa and Functional Gene Composition.

Deaver JA, Eum SY, Toborek M.

Front Microbiol. 2018 Apr 13;9:737. doi: 10.3389/fmicb.2018.00737. eCollection 2018.

5.

Comparison of the characteristics of Mycobacterium tuberculosis isolates from sputum and lung lesions in chronic tuberculosis patients.

Hong MS, Kim Y, Cho EJ, Lee JS, Kwak HK, Kim JH, Kim CT, Cho JS, Park SK, Jeon D, Choi YI, Lee H, Eum SY.

Eur J Clin Microbiol Infect Dis. 2017 Nov;36(11):2063-2072. doi: 10.1007/s10096-017-3025-5. Epub 2017 Jun 15.

PMID:
28620844
6.

Development of simulation-based learning programme for improving adherence to time-out protocol on high-risk invasive procedures outside of operating room.

Jeong EJ, Chung HS, Choi JY, Kim IS, Hong SH, Yoo KS, Kim MK, Won MY, Eum SY, Cho YS.

Int J Nurs Pract. 2017 Jun;23(3). doi: 10.1111/ijn.12529. Epub 2017 Feb 7.

PMID:
28176420
7.

Navigation programs, are they helpful for perioperative care with thyroid cancer patients?

Park KA, Oh YJ, Kim KM, Eum SY, Cho MH, Son YH, Park SH, Woo KM, Lee YS, Kim S, Chang HS, Park CS.

Eur J Cancer Care (Engl). 2017 Jul;26(4). doi: 10.1111/ecc.12592. Epub 2016 Oct 11.

PMID:
27726224
8.

Inflammatory signaling in human tuberculosis granulomas is spatially organized.

Marakalala MJ, Raju RM, Sharma K, Zhang YJ, Eugenin EA, Prideaux B, Daudelin IB, Chen PY, Booty MG, Kim JH, Eum SY, Via LE, Behar SM, Barry CE 3rd, Mann M, Dartois V, Rubin EJ.

Nat Med. 2016 May;22(5):531-8. doi: 10.1038/nm.4073. Epub 2016 Apr 4.

9.

Development and validation of LC-ESI-MS/MS method for analysis of moxifloxacin and levofloxacin in serum of multidrug-resistant tuberculosis patients: Potential application as therapeutic drug monitoring tool in medical diagnosis.

Lee SJ, Desta KT, Eum SY, Dartois V, Cho SN, Bae DW, Shin SC.

J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jan 15;1009-1010:138-43. doi: 10.1016/j.jchromb.2015.11.058. Epub 2015 Dec 8.

PMID:
26730550
10.

Virulence-Dependent Alterations in the Kinetics of Immune Cells during Pulmonary Infection by Mycobacterium tuberculosis.

Kim WS, Kim JS, Cha SB, Han SJ, Kim H, Kwon KW, Kim SJ, Eum SY, Cho SN, Shin SJ.

PLoS One. 2015 Dec 16;10(12):e0145234. doi: 10.1371/journal.pone.0145234. eCollection 2015.

11.

Repeated Aerosolized-Boosting with Gamma-Irradiated Mycobacterium bovis BCG Confers Improved Pulmonary Protection against the Hypervirulent Mycobacterium tuberculosis Strain HN878 in Mice.

Cha SB, Kim WS, Kim JS, Kim H, Kwon KW, Han SJ, Eum SY, Cho SN, Shin SJ.

PLoS One. 2015 Oct 28;10(10):e0141577. doi: 10.1371/journal.pone.0141577. eCollection 2015.

12.

Lipid rafts regulate PCB153-induced disruption of occludin and brain endothelial barrier function through protein phosphatase 2A and matrix metalloproteinase-2.

Eum SY, Jaraki D, András IE, Toborek M.

Toxicol Appl Pharmacol. 2015 Sep 15;287(3):258-66. doi: 10.1016/j.taap.2015.06.011. Epub 2015 Jun 14.

13.

Potential role of immunodiagnosis for pulmonary tuberculosis using induced sputum cells.

Jeon D, Lee SE, Cho WH, Lee BH, Kim YS, Lee JE, Son ES, Lee YJ, Hong MS, Eum SY.

Yonsei Med J. 2015 Mar;56(2):340-7. doi: 10.3349/ymj.2015.56.2.340.

14.

Essential engagement of Toll-like receptor 2 in initiation of early protective Th1 response against rough variants of Mycobacterium abscessus.

Kim JS, Kang MJ, Kim WS, Han SJ, Kim HM, Kim HW, Kwon KW, Kim SJ, Cha SB, Eum SY, Koh WJ, Cho SN, Park JH, Shin SJ.

Infect Immun. 2015 Apr;83(4):1556-67. doi: 10.1128/IAI.02853-14. Epub 2015 Feb 2.

15.

Selenoglycoproteins attenuate adhesion of tumor cells to the brain microvascular endothelium via a process involving NF-κB activation.

Wrobel JK, Choi JJ, Xiao R, Eum SY, Kwiatkowski S, Wolff G, Spangler L, Power RF, Toborek M.

J Nutr Biochem. 2015 Feb;26(2):120-9. doi: 10.1016/j.jnutbio.2014.09.013. Epub 2014 Oct 28.

16.

Transcriptional profile of HIV-induced nuclear translocation of amyloid β in brain endothelial cells.

András IE, Rampersaud E, Eum SY, Toborek M.

Arch Med Res. 2014 Nov;45(8):744-52. doi: 10.1016/j.arcmed.2014.11.003. Epub 2014 Nov 13.

17.

Disruption of epithelial barrier by quorum-sensing N-3-(oxododecanoyl)-homoserine lactone is mediated by matrix metalloproteinases.

Eum SY, Jaraki D, Bertrand L, András IE, Toborek M.

Am J Physiol Gastrointest Liver Physiol. 2014 Jun 1;306(11):G992-G1001. doi: 10.1152/ajpgi.00016.2014. Epub 2014 Apr 17.

18.

Myriocin induces apoptotic lung cancer cell death via activation of DR4 pathway.

Choi KE, Jung YS, Kim DH, Song JK, Kim JY, Jung YY, Eum SY, Kim JH, Yoon NY, Yoo HS, Han SB, Hong JT.

Arch Pharm Res. 2014 Apr;37(4):501-11. doi: 10.1007/s12272-013-0315-z. Epub 2014 Jan 7.

PMID:
24395529
19.

Curative Effects of Thiacremonone against Acetaminophen-Induced Acute Hepatic Failure via Inhibition of Proinflammatory Cytokines Production and Infiltration of Cytotoxic Immune Cells and Kupffer Cells.

Kim YR, Lee NJ, Ban JO, Yoo HS, Lee YM, Yoon YP, Eum SY, Jeong HS, Yoon DY, Han SB, Hong JT.

Evid Based Complement Alternat Med. 2013;2013:974794. doi: 10.1155/2013/974794. Epub 2013 Jul 11.

20.

Microenvironments in tuberculous granulomas are delineated by distinct populations of macrophage subsets and expression of nitric oxide synthase and arginase isoforms.

Mattila JT, Ojo OO, Kepka-Lenhart D, Marino S, Kim JH, Eum SY, Via LE, Barry CE 3rd, Klein E, Kirschner DE, Morris SM Jr, Lin PL, Flynn JL.

J Immunol. 2013 Jul 15;191(2):773-84. doi: 10.4049/jimmunol.1300113. Epub 2013 Jun 7.

21.

Efficacy and safety of metronidazole for pulmonary multidrug-resistant tuberculosis.

Carroll MW, Jeon D, Mountz JM, Lee JD, Jeong YJ, Zia N, Lee M, Lee J, Via LE, Lee S, Eum SY, Lee SJ, Goldfeder LC, Cai Y, Jin B, Kim Y, Oh T, Chen RY, Dodd LE, Gu W, Dartois V, Park SK, Kim CT, Barry CE 3rd, Cho SN.

Antimicrob Agents Chemother. 2013 Aug;57(8):3903-9. doi: 10.1128/AAC.00753-13. Epub 2013 Jun 3.

22.

Differential virulence and disease progression following Mycobacterium tuberculosis complex infection of the common marmoset (Callithrix jacchus).

Via LE, Weiner DM, Schimel D, Lin PL, Dayao E, Tankersley SL, Cai Y, Coleman MT, Tomko J, Paripati P, Orandle M, Kastenmayer RJ, Tartakovsky M, Rosenthal A, Portevin D, Eum SY, Lahouar S, Gagneux S, Young DB, Flynn JL, Barry CE 3rd.

Infect Immun. 2013 Aug;81(8):2909-19. doi: 10.1128/IAI.00632-13. Epub 2013 May 28.

23.

TLR4 signaling is involved in brain vascular toxicity of PCB153 bound to nanoparticles.

Zhang B, Choi JJ, Eum SY, Daunert S, Toborek M.

PLoS One. 2013 May 14;8(5):e63159. doi: 10.1371/journal.pone.0063159. Print 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/e34adc2a-f73a-4055-8519-fa2deb2e852f.

24.

Exercise attenuates PCB-induced changes in the mouse gut microbiome.

Choi JJ, Eum SY, Rampersaud E, Daunert S, Abreu MT, Toborek M.

Environ Health Perspect. 2013 Jun;121(6):725-30. doi: 10.1289/ehp.1306534. Epub 2013 Apr 26.

25.

Differential immune responses to Segniliparus rotundus and Segniliparus rugosus infection and analysis of their comparative virulence profiles.

Kim JS, Kim WS, Lee K, Won CJ, Kim JM, Eum SY, Koh WJ, Shin SJ.

PLoS One. 2013;8(3):e59646. doi: 10.1371/journal.pone.0059646. Epub 2013 Mar 29.

26.
27.

Prevalence of and risk factors for resistance to second-line drugs in people with multidrug-resistant tuberculosis in eight countries: a prospective cohort study.

Dalton T, Cegielski P, Akksilp S, Asencios L, Campos Caoili J, Cho SN, Erokhin VV, Ershova J, Gler MT, Kazennyy BY, Kim HJ, Kliiman K, Kurbatova E, Kvasnovsky C, Leimane V, van der Walt M, Via LE, Volchenkov GV, Yagui MA, Kang H; Global PETTS Investigators, Akksilp R, Sitti W, Wattanaamornkiet W, Andreevskaya SN, Chernousova LN, Demikhova OV, Larionova EE, Smirnova TG, Vasilieva IA, Vorobyeva AV, Barry CE 3rd, Cai Y, Shamputa IC, Bayona J, Contreras C, Bonilla C, Jave O, Brand J, Lancaster J, Odendaal R, Chen MP, Diem L, Metchock B, Tan K, Taylor A, Wolfgang M, Cho E, Eum SY, Kwak HK, Lee J, Lee J, Min S, Degtyareva I, Nemtsova ES, Khorosheva T, Kyryanova EV, Egos G, Perez MT, Tupasi T, Hwang SH, Kim CK, Kim SY, Lee HJ, Kuksa L, Norvaisha I, Skenders G, Sture I, Kummik T, Kuznetsova T, Somova T, Levina K, Pariona G, Yale G, Suarez C, Valencia E, Viiklepp P.

Lancet. 2012 Oct 20;380(9851):1406-17. doi: 10.1016/S0140-6736(12)60734-X. Epub 2012 Aug 30. Erratum in: Lancet. 2012 Oct 20;380(9851):1386.

PMID:
22938757
28.

Lipopolysaccharide potentiates polychlorinated biphenyl-induced disruption of the blood-brain barrier via TLR4/IRF-3 signaling.

Choi JJ, Choi YJ, Chen L, Zhang B, Eum SY, Abreu MT, Toborek M.

Toxicology. 2012 Dec 16;302(2-3):212-20. doi: 10.1016/j.tox.2012.08.001. Epub 2012 Aug 13.

29.

In vivo characteristics of Korean Beijing Mycobacterium tuberculosis strain K1 in an aerosol challenge model and in the Cornell latent tuberculosis model.

Jeon BY, Kwak J, Hahn MY, Eum SY, Yang J, Kim SC, Cho SN.

J Med Microbiol. 2012 Oct;61(Pt 10):1373-9. doi: 10.1099/jmm.0.047027-0. Epub 2012 Jul 19.

PMID:
22820694
30.

Lipid rafts and functional caveolae regulate HIV-induced amyloid beta accumulation in brain endothelial cells.

András IE, Eum SY, Toborek M.

Biochem Biophys Res Commun. 2012 May 4;421(2):177-83. doi: 10.1016/j.bbrc.2012.03.128. Epub 2012 Apr 3.

31.

Proinflammatory adhesion molecules facilitate polychlorinated biphenyl-mediated enhancement of brain metastasis formation.

Sipos E, Chen L, András IE, Wrobel J, Zhang B, Pu H, Park M, Eum SY, Toborek M.

Toxicol Sci. 2012 Apr;126(2):362-71. doi: 10.1093/toxsci/kfr349. Epub 2012 Jan 12.

32.

HIV-1 Tat triggers nuclear localization of ZO-1 via Rho signaling and cAMP response element-binding protein activation.

Zhong Y, Zhang B, Eum SY, Toborek M.

J Neurosci. 2012 Jan 4;32(1):143-50. doi: 10.1523/JNEUROSCI.4266-11.2012.

33.

Mycolic acids as diagnostic markers for tuberculosis case detection in humans and drug efficacy in mice.

Shui G, Bendt AK, Jappar IA, Lim HM, Laneelle M, Hervé M, Via LE, Chua GH, Bratschi MW, Zainul Rahim SZ, Michelle AL, Hwang SH, Lee JS, Eum SY, Kwak HK, Daffé M, Dartois V, Michel G, Barry CE 3rd, Wenk MR.

EMBO Mol Med. 2012 Jan;4(1):27-37. doi: 10.1002/emmm.201100185. Epub 2011 Dec 7.

34.

Changes in cell-mediated immune response after lung resection surgery for MDR-TB patients.

Park SK, Hong S, Eum SY, Lee IH, Shin DO, Cho JE, Cho S, Cho SN.

Tuberculosis (Edinb). 2011 Jul;91(4):300-7. doi: 10.1016/j.tube.2011.02.003. Epub 2011 Apr 22.

PMID:
21514229
35.

The immunity and protective effects of antigen 85A and heat-shock protein X against progressive tuberculosis.

Jeon BY, Kim SC, Eum SY, Cho SN.

Microbes Infect. 2011 Mar;13(3):284-90. doi: 10.1016/j.micinf.2010.11.002. Epub 2010 Nov 18.

PMID:
21093603
36.

Deficiency of telomerase activity aggravates the blood-brain barrier disruption and neuroinflammatory responses in a model of experimental stroke.

Zhang B, Chen L, Swartz KR, Bruemmer D, Eum SY, Huang W, Seelbach M, Choi YJ, Hennig B, Toborek M.

J Neurosci Res. 2010 Oct;88(13):2859-68. doi: 10.1002/jnr.22450.

37.

Metaplastic ossification in the cartilage of the bronchus of a patient with chronic multi-drug resistant tuberculosis: a case report.

Eum SY, Kong JH, Jeon BY, Cho SN, Kim J, Via LE, Barry Iii CE, Koh WJ.

J Med Case Rep. 2010 May 26;4:156. doi: 10.1186/1752-1947-4-156.

38.

Polychlorinated biphenyl-induced VCAM-1 expression is attenuated in aortic endothelial cells isolated from caveolin-1 deficient mice.

Han SG, Eum SY, Toborek M, Smart E, Hennig B.

Toxicol Appl Pharmacol. 2010 Jul;246(1-2):74-82. doi: 10.1016/j.taap.2010.04.009. Epub 2010 Apr 18.

39.

Polychlorinated biphenyls disrupt intestinal integrity via NADPH oxidase-induced alterations of tight junction protein expression.

Choi YJ, Seelbach MJ, Pu H, Eum SY, Chen L, Zhang B, Hennig B, Toborek M.

Environ Health Perspect. 2010 Jul;118(7):976-81. doi: 10.1289/ehp.0901751. Epub 2010 Mar 18.

40.

Association of antigen-stimulated release of tumor necrosis factor-alpha in whole blood with response to chemotherapy in patients with pulmonary multidrug-resistant tuberculosis.

Eum SY, Lee YJ, Min JH, Kwak HK, Hong MS, Kong JH, Hwang SH, Park SK, Leblanc JJ, Via LE, Barry CE 3rd, Cho SN.

Respiration. 2010;80(4):275-84. doi: 10.1159/000283687. Epub 2010 Feb 10.

41.

Genetic diversity of Mycobacterium tuberculosis isolates from a tertiary care tuberculosis hospital in South Korea.

Shamputa IC, Lee J, Allix-Béguec C, Cho EJ, Lee JI, Rajan V, Lee EG, Min JH, Carroll MW, Goldfeder LC, Kim JH, Kang HS, Hwang S, Eum SY, Park SK, Lee H, Supply P, Cho SN, Via LE, Barry CE 3rd.

J Clin Microbiol. 2010 Feb;48(2):387-94. doi: 10.1128/JCM.02167-09. Epub 2009 Dec 16.

42.

HIV-1-induced amyloid beta accumulation in brain endothelial cells is attenuated by simvastatin.

András IE, Eum SY, Huang W, Zhong Y, Hennig B, Toborek M.

Mol Cell Neurosci. 2010 Feb;43(2):232-43. doi: 10.1016/j.mcn.2009.11.004. Epub 2009 Nov 26.

43.

Neutrophils are the predominant infected phagocytic cells in the airways of patients with active pulmonary TB.

Eum SY, Kong JH, Hong MS, Lee YJ, Kim JH, Hwang SH, Cho SN, Via LE, Barry CE 3rd.

Chest. 2010 Jan;137(1):122-8. doi: 10.1378/chest.09-0903. Epub 2009 Sep 11.

44.

NADPH oxidase and lipid raft-associated redox signaling are required for PCB153-induced upregulation of cell adhesion molecules in human brain endothelial cells.

Eum SY, Andras I, Hennig B, Toborek M.

Toxicol Appl Pharmacol. 2009 Oct 15;240(2):299-305. doi: 10.1016/j.taap.2009.07.022. Epub 2009 Jul 24.

45.

PPARalpha and PPARgamma attenuate HIV-induced dysregulation of tight junction proteins by modulations of matrix metalloproteinase and proteasome activities.

Huang W, Eum SY, András IE, Hennig B, Toborek M.

FASEB J. 2009 May;23(5):1596-606. doi: 10.1096/fj.08-121624. Epub 2009 Jan 13.

46.

PPARalpha and PPARgamma effectively protect against HIV-induced inflammatory responses in brain endothelial cells.

Huang W, Rha GB, Han MJ, Eum SY, András IE, Zhong Y, Hennig B, Toborek M.

J Neurochem. 2008 Oct;107(2):497-509. doi: 10.1111/j.1471-4159.2008.05626.x. Epub 2008 Aug 14.

47.

Pcbs and tight junction expression.

Eum SY, András IE, Couraud PO, Hennig B, Toborek M.

Environ Toxicol Pharmacol. 2008 Mar;25(2):234-40. doi: 10.1016/j.etap.2007.10.019.

48.

ORAL ADMINISTRATION OF PCBs INDUCES PROINFLAMMATORY AND PROMETASTATIC RESPONSES.

Sipka S, Eum SY, Son KW, Xu S, Gavalas VG, Hennig B, Toborek M.

Environ Toxicol Pharmacol. 2008 Mar;25(2):251-9. doi: 10.1016/j.etap.2007.10.020.

49.

Tuberculous granulomas are hypoxic in guinea pigs, rabbits, and nonhuman primates.

Via LE, Lin PL, Ray SM, Carrillo J, Allen SS, Eum SY, Taylor K, Klein E, Manjunatha U, Gonzales J, Lee EG, Park SK, Raleigh JA, Cho SN, McMurray DN, Flynn JL, Barry CE 3rd.

Infect Immun. 2008 Jun;76(6):2333-40. doi: 10.1128/IAI.01515-07. Epub 2008 Mar 17.

50.

Evaluation of the diagnostic utility of a whole-blood interferon-gamma assay for determining the risk of exposure to Mycobacterium tuberculosis in Bacille Calmette-Guerin (BCG)-vaccinated individuals.

Eum SY, Lee YJ, Kwak HK, Min JH, Hwang SH, Via LE, Barry CE 3rd, Cho SN.

Diagn Microbiol Infect Dis. 2008 Jun;61(2):181-6. doi: 10.1016/j.diagmicrobio.2008.01.002. Epub 2008 Mar 4.

Supplemental Content

Support Center