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Items: 5

1.

Clinical Reasoning: A 35-year-old woman with diplopia, ataxia, and altered mental status.

Bauer Z, Eum KS, Ji J, Bunin J, Sherratt J.

Neurology. 2018 Nov 13;91(20):e1942-e1946. doi: 10.1212/WNL.0000000000006499. No abstract available.

PMID:
30420464
2.

The tarantula toxin GxTx detains K+ channel gating charges in their resting conformation.

Tilley DC, Angueyra JM, Eum KS, Kim H, Chao LH, Peng AW, Sack JT.

J Gen Physiol. 2018 Nov 5. pii: jgp.201812213. doi: 10.1085/jgp.201812213. [Epub ahead of print]

PMID:
30397012
3.

Synthetic Analogues of the Snail Toxin 6-Bromo-2-mercaptotryptamine Dimer (BrMT) Reveal That Lipid Bilayer Perturbation Does Not Underlie Its Modulation of Voltage-Gated Potassium Channels.

Dockendorff C, Gandhi DM, Kimball IH, Eum KS, Rusinova R, Ingólfsson HI, Kapoor R, Peyear T, Dodge MW, Martin SF, Aldrich RW, Andersen OS, Sack JT.

Biochemistry. 2018 May 8;57(18):2733-2743. doi: 10.1021/acs.biochem.8b00292. Epub 2018 Apr 17.

4.

A novel epileptic encephalopathy mutation in KCNB1 disrupts Kv2.1 ion selectivity, expression, and localization.

Thiffault I, Speca DJ, Austin DC, Cobb MM, Eum KS, Safina NP, Grote L, Farrow EG, Miller N, Soden S, Kingsmore SF, Trimmer JS, Saunders CJ, Sack JT.

J Gen Physiol. 2015 Nov;146(5):399-410. doi: 10.1085/jgp.201511444.

5.

Chemoselective tarantula toxins report voltage activation of wild-type ion channels in live cells.

Tilley DC, Eum KS, Fletcher-Taylor S, Austin DC, Dupré C, Patrón LA, Garcia RL, Lam K, Yarov-Yarovoy V, Cohen BE, Sack JT.

Proc Natl Acad Sci U S A. 2014 Nov 4;111(44):E4789-96. doi: 10.1073/pnas.1406876111. Epub 2014 Oct 20.

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