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Items: 18


Isolation of Phage Lysins That Effectively Kill Pseudomonas aeruginosa in Mouse Models of Lung and Skin Infection.

Raz A, Serrano A, Hernandez A, Euler CW, Fischetti VA.

Antimicrob Agents Chemother. 2019 Jun 24;63(7). pii: e00024-19. doi: 10.1128/AAC.00024-19. Print 2019 Jul.


Lysocins: Bioengineered Antimicrobials That Deliver Lysins across the Outer Membrane of Gram-Negative Bacteria.

Heselpoth RD, Euler CW, Schuch R, Fischetti VA.

Antimicrob Agents Chemother. 2019 May 24;63(6). pii: e00342-19. doi: 10.1128/AAC.00342-19. Print 2019 Jun.


Staphylococcus aureus Infecting and Colonizing Experimental Animals, Macaques, in a Research Animal Facility.

Pardos de la Gandara M, Diaz L, Euler CW, Chung M, Gonzalez A, Cheleuitte C, Freiwald W, Tomasz A, Fischetti VA, de Lencastre H.

Microb Drug Resist. 2019 Jan/Feb;25(1):54-62. doi: 10.1089/mdr.2018.0232. Epub 2018 Nov 27.


Strains of bacterial species induce a greatly varied acute adaptive immune response: The contribution of the accessory genome.

Sela U, Euler CW, Correa da Rosa J, Fischetti VA.

PLoS Pathog. 2018 Jan 11;14(1):e1006726. doi: 10.1371/journal.ppat.1006726. eCollection 2018 Jan.


The Phage Lysin PlySs2 Decolonizes Streptococcus suis from Murine Intranasal Mucosa.

Gilmer DB, Schmitz JE, Thandar M, Euler CW, Fischetti VA.

PLoS One. 2017 Jan 3;12(1):e0169180. doi: 10.1371/journal.pone.0169180. eCollection 2017.


Novel Engineered Peptides of a Phage Lysin as Effective Antimicrobials against Multidrug-Resistant Acinetobacter baumannii.

Thandar M, Lood R, Winer BY, Deutsch DR, Euler CW, Fischetti VA.

Antimicrob Agents Chemother. 2016 Apr 22;60(5):2671-9. doi: 10.1128/AAC.02972-15. Print 2016 May.


Targeted Curing of All Lysogenic Bacteriophage from Streptococcus pyogenes Using a Novel Counter-selection Technique.

Euler CW, Juncosa B, Ryan PA, Deutsch DR, McShan WM, Fischetti VA.

PLoS One. 2016 Jan 12;11(1):e0146408. doi: 10.1371/journal.pone.0146408. eCollection 2016.


Elimination of Chromosomal Island SpyCIM1 from Streptococcus pyogenes Strain SF370 Reverses the Mutator Phenotype and Alters Global Transcription.

Hendrickson C, Euler CW, Nguyen SV, Rahman M, McCullor KA, King CJ, Fischetti VA, McShan WM.

PLoS One. 2015 Dec 23;10(12):e0145884. doi: 10.1371/journal.pone.0145884. eCollection 2015.


Using a Novel Lysin To Help Control Clostridium difficile Infections.

Wang Q, Euler CW, Delaune A, Fischetti VA.

Antimicrob Agents Chemother. 2015 Dec;59(12):7447-57. doi: 10.1128/AAC.01357-15. Epub 2015 Sep 21.


A novel chimeric phage lysin with high in vitro and in vivo bactericidal activity against Streptococcus pneumoniae.

Díez-Martínez R, De Paz HD, García-Fernández E, Bustamante N, Euler CW, Fischetti VA, Menendez M, García P.

J Antimicrob Chemother. 2015;70(6):1763-73. doi: 10.1093/jac/dkv038. Epub 2015 Mar 1.


Novel phage lysin capable of killing the multidrug-resistant gram-negative bacterium Acinetobacter baumannii in a mouse bacteremia model.

Lood R, Winer BY, Pelzek AJ, Diez-Martinez R, Thandar M, Euler CW, Schuch R, Fischetti VA.

Antimicrob Agents Chemother. 2015 Apr;59(4):1983-91. doi: 10.1128/AAC.04641-14. Epub 2015 Jan 20.


Exploiting CRISPR-Cas nucleases to produce sequence-specific antimicrobials.

Bikard D, Euler CW, Jiang W, Nussenzweig PM, Goldberg GW, Duportet X, Fischetti VA, Marraffini LA.

Nat Biotechnol. 2014 Nov;32(11):1146-50. doi: 10.1038/nbt.3043. Epub 2014 Oct 5.


A highly active and negatively charged Streptococcus pyogenes lysin with a rare D-alanyl-L-alanine endopeptidase activity protects mice against streptococcal bacteremia.

Lood R, Raz A, Molina H, Euler CW, Fischetti VA.

Antimicrob Agents Chemother. 2014 Jun;58(6):3073-84. doi: 10.1128/AAC.00115-14. Epub 2014 Mar 17.


Use of a bacteriophage lysin to identify a novel target for antimicrobial development.

Schuch R, Pelzek AJ, Raz A, Euler CW, Ryan PA, Winer BY, Farnsworth A, Bhaskaran SS, Stebbins CE, Xu Y, Clifford A, Bearss DJ, Vankayalapati H, Goldberg AR, Fischetti VA.

PLoS One. 2013 Apr 10;8(4):e60754. doi: 10.1371/journal.pone.0060754. Print 2013.


Novel bacteriophage lysin with broad lytic activity protects against mixed infection by Streptococcus pyogenes and methicillin-resistant Staphylococcus aureus.

Gilmer DB, Schmitz JE, Euler CW, Fischetti VA.

Antimicrob Agents Chemother. 2013 Jun;57(6):2743-50. doi: 10.1128/AAC.02526-12. Epub 2013 Apr 9.


Novel algorithms reveal streptococcal transcriptomes and clues about undefined genes.

Ryan PA, Kirk BW, Euler CW, Schuch R, Fischetti VA.

PLoS Comput Biol. 2007 Jul;3(7):e132.


M.SpyI, a DNA methyltransferase encoded on a mefA chimeric element, modifies the genome of Streptococcus pyogenes.

Euler CW, Ryan PA, Martin JM, Fischetti VA.

J Bacteriol. 2007 Feb;189(3):1044-54. Epub 2006 Nov 3.


Activation of rheumatoid factor (RF) B cells and somatic hypermutation outside of germinal centers in autoimmune-prone MRL/lpr mice.

Shlomchik MJ, Euler CW, Christensen SC, William J.

Ann N Y Acad Sci. 2003 Apr;987:38-50. Review.


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