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Items: 23

1.

Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression.

Etzerodt A, Tsalkitzi K, Maniecki M, Damsky W, Delfini M, Baudoin E, Moulin M, Bosenberg M, Graversen JH, Auphan-Anezin N, Moestrup SK, Lawrence T.

J Exp Med. 2019 Aug 2. pii: jem.20182124. doi: 10.1084/jem.20182124. [Epub ahead of print]

PMID:
31375534
2.

The macrophage-related biomarkers sCD163 and sCD206 are released by different shedding mechanisms.

Nielsen MC, Andersen MN, Rittig N, Rødgaard-Hansen S, Grønbaek H, Moestrup SK, Møller HJ, Etzerodt A.

J Leukoc Biol. 2019 Jun 26. doi: 10.1002/JLB.3A1218-500R. [Epub ahead of print]

PMID:
31242338
3.

Targeted lipid nanoparticle delivery of calcitriol to human monocyte-derived macrophages in vitro and in vivo: investigation of the anti-inflammatory effects of calcitriol.

Rafique A, Etzerodt A, Graversen JH, Moestrup SK, Dagnæs-Hansen F, Møller HJ.

Int J Nanomedicine. 2019 Apr 23;14:2829-2846. doi: 10.2147/IJN.S192113. eCollection 2019.

4.

Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression.

Goossens P, Rodriguez-Vita J, Etzerodt A, Masse M, Rastoin O, Gouirand V, Ulas T, Papantonopoulou O, Van Eck M, Auphan-Anezin N, Bebien M, Verthuy C, Vu Manh TP, Turner M, Dalod M, Schultze JL, Lawrence T.

Cell Metab. 2019 Jun 4;29(6):1376-1389.e4. doi: 10.1016/j.cmet.2019.02.016. Epub 2019 Mar 28.

PMID:
30930171
5.

STAT3 inhibition specifically in human monocytes and macrophages by CD163-targeted corosolic acid-containing liposomes.

Andersen MN, Etzerodt A, Graversen JH, Holthof LC, Moestrup SK, Hokland M, Møller HJ.

Cancer Immunol Immunother. 2019 Mar;68(3):489-502. doi: 10.1007/s00262-019-02301-3. Epub 2019 Jan 14.

PMID:
30637473
6.

Structural assembly of the megadalton-sized receptor for intestinal vitamin B12 uptake and kidney protein reabsorption.

Larsen C, Etzerodt A, Madsen M, Skjødt K, Moestrup SK, Andersen CBF.

Nat Commun. 2018 Dec 6;9(1):5204. doi: 10.1038/s41467-018-07468-4.

7.

Antibody-Directed Glucocorticoid Targeting to CD163 in M2-type Macrophages Attenuates Fructose-Induced Liver Inflammatory Changes.

Svendsen P, Graversen JH, Etzerodt A, Hager H, Røge R, Grønbæk H, Christensen EI, Møller HJ, Vilstrup H, Moestrup SK.

Mol Ther Methods Clin Dev. 2016 Dec 24;4:50-61. doi: 10.1016/j.omtm.2016.11.004. eCollection 2017 Mar 17.

8.

Soluble ectodomain CD163 and extracellular vesicle-associated CD163 are two differently regulated forms of 'soluble CD163' in plasma.

Etzerodt A, Berg RM, Plovsing RR, Andersen MN, Bebien M, Habbeddine M, Lawrence T, Møller HJ, Moestrup SK.

Sci Rep. 2017 Jan 13;7:40286. doi: 10.1038/srep40286.

9.

The Staphylococcus aureus Protein IsdH Inhibits Host Hemoglobin Scavenging to Promote Heme Acquisition by the Pathogen.

Sæderup KL, Stødkilde K, Graversen JH, Dickson CF, Etzerodt A, Hansen SW, Fago A, Gell D, Andersen CB, Moestrup SK.

J Biol Chem. 2016 Nov 11;291(46):23989-23998. Epub 2016 Sep 28.

10.

Anti-Inflammatory Modulation of Microglia via CD163-Targeted Glucocorticoids Protects Dopaminergic Neurons in the 6-OHDA Parkinson's Disease Model.

Tentillier N, Etzerodt A, Olesen MN, Rizalar FS, Jacobsen J, Bender D, Moestrup SK, Romero-Ramos M.

J Neurosci. 2016 Sep 7;36(36):9375-90. doi: 10.1523/JNEUROSCI.1636-16.2016.

11.

A disintegrin and metalloprotease-17 and galectin-9 are important regulators of local 4-1BB activity and disease outcome in rheumatoid arthritis.

Nielsen MA, Andersen T, Etzerodt A, Kragstrup TW, Rasmussen TK, Stengaard-Pedersen K, Hetland ML, Hørslev-Petersen K, Junker P, Østergaard M, Hvid M, Moestrup SK, Deleuran B.

Rheumatology (Oxford). 2016 Oct;55(10):1871-9. doi: 10.1093/rheumatology/kew237. Epub 2016 Jun 21.

PMID:
27330157
12.

Anti-inflammatory liposomes have no impact on liver regeneration in rats.

Jepsen BN, Andersen KJ, Knudsen AR, Nyengaard JR, Hamilton-Dutoit S, Svendsen P, Etzerodt A, Møller HJ, Moestrup SK, Graversen JH, Mortensen FV.

Ann Med Surg (Lond). 2015 Nov 2;4(4):452-61. doi: 10.1016/j.amsu.2015.10.018. eCollection 2015 Dec.

13.

Structural basis for inflammation-driven shedding of CD163 ectodomain and tumor necrosis factor-α in macrophages.

Etzerodt A, Rasmussen MR, Svendsen P, Chalaris A, Schwarz J, Galea I, Møller HJ, Moestrup SK.

J Biol Chem. 2014 Jan 10;289(2):778-88. doi: 10.1074/jbc.M113.520213. Epub 2013 Nov 25.

14.

Obesity alters adipose tissue macrophage iron content and tissue iron distribution.

Orr JS, Kennedy A, Anderson-Baucum EK, Webb CD, Fordahl SC, Erikson KM, Zhang Y, Etzerodt A, Moestrup SK, Hasty AH.

Diabetes. 2014 Feb;63(2):421-32. doi: 10.2337/db13-0213. Epub 2013 Oct 15.

15.

Targeting dexamethasone to macrophages in a porcine endotoxemic model.

Granfeldt A, Hvas CL, Graversen JH, Christensen PA, Petersen MD, Anton G, Svendsen P, Sølling C, Etzerodt A, Tønnesen E, Moestrup SK, Møller HJ.

Crit Care Med. 2013 Nov;41(11):e309-18. doi: 10.1097/CCM.0b013e31828a45ef.

PMID:
23928834
16.

The haptoglobin-CD163-heme oxygenase-1 pathway for hemoglobin scavenging.

Thomsen JH, Etzerodt A, Svendsen P, Moestrup SK.

Oxid Med Cell Longev. 2013;2013:523652. doi: 10.1155/2013/523652. Epub 2013 May 27. Review.

17.

CD163 and inflammation: biological, diagnostic, and therapeutic aspects.

Etzerodt A, Moestrup SK.

Antioxid Redox Signal. 2013 Jun 10;18(17):2352-63. doi: 10.1089/ars.2012.4834. Epub 2012 Oct 19. Review.

18.

Plasma clearance of hemoglobin and haptoglobin in mice and effect of CD163 gene targeting disruption.

Etzerodt A, Kjolby M, Nielsen MJ, Maniecki M, Svendsen P, Moestrup SK.

Antioxid Redox Signal. 2013 Jun 10;18(17):2254-63. doi: 10.1089/ars.2012.4605. Epub 2012 Aug 29.

PMID:
22793784
19.

Targeting the hemoglobin scavenger receptor CD163 in macrophages highly increases the anti-inflammatory potency of dexamethasone.

Graversen JH, Svendsen P, Dagnæs-Hansen F, Dal J, Anton G, Etzerodt A, Petersen MD, Christensen PA, Møller HJ, Moestrup SK.

Mol Ther. 2012 Aug;20(8):1550-8. doi: 10.1038/mt.2012.103. Epub 2012 May 29.

20.

Tumor-promoting macrophages induce the expression of the macrophage-specific receptor CD163 in malignant cells.

Maniecki MB, Etzerodt A, Ulhøi BP, Steiniche T, Borre M, Dyrskjøt L, Orntoft TF, Moestrup SK, Møller HJ.

Int J Cancer. 2012 Nov 15;131(10):2320-31. doi: 10.1002/ijc.27506. Epub 2012 Mar 28.

21.

Efficient intracellular drug-targeting of macrophages using stealth liposomes directed to the hemoglobin scavenger receptor CD163.

Etzerodt A, Maniecki MB, Graversen JH, Møller HJ, Torchilin VP, Moestrup SK.

J Control Release. 2012 May 30;160(1):72-80. doi: 10.1016/j.jconrel.2012.01.034. Epub 2012 Jan 27.

PMID:
22306335
22.

Comparative assessment of the recognition of domain-specific CD163 monoclonal antibodies in human monocytes explains wide discrepancy in reported levels of cellular surface CD163 expression.

Maniecki MB, Etzerodt A, Moestrup SK, Møller HJ, Graversen JH.

Immunobiology. 2011 Aug;216(8):882-90. doi: 10.1016/j.imbio.2011.02.001. Epub 2011 Feb 22.

PMID:
21458881
23.

Tumor necrosis factor α-converting enzyme (TACE/ADAM17) mediates ectodomain shedding of the scavenger receptor CD163.

Etzerodt A, Maniecki MB, Møller K, Møller HJ, Moestrup SK.

J Leukoc Biol. 2010 Dec;88(6):1201-5. doi: 10.1189/jlb.0410235. Epub 2010 Aug 31.

PMID:
20807704

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