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Items: 30


FVIII proteins with a modified immunodominant T-cell epitope exhibit reduced immunogenicity and normal FVIII activity.

Ettinger RA, Liberman JA, Gunasekera D, Puranik K, James EA, Thompson AR, Pratt KP.

Blood Adv. 2018 Feb 27;2(4):309-322. doi: 10.1182/bloodadvances.2017013482.


NaF rinse and dentifrice concentrations on enamel lesion demineralization.

Goettsche ZS, Ettinger RA, Hogan MM, Harless JD, Qian F.

Am J Dent. 2016 Oct;29(5):243-247.


T cells from hemophilia A subjects recognize the same HLA-restricted FVIII epitope with a narrow TCR repertoire.

Ettinger RA, Paz P, James EA, Gunasekera D, Aswad F, Thompson AR, Matthews DC, Pratt KP.

Blood. 2016 Oct 20;128(16):2043-2054. doi: 10.1182/blood-2015-11-682468. Epub 2016 Jul 28.


Factor VIII gene variants and inhibitor risk in African American hemophilia A patients.

Gunasekera D, Ettinger RA, Nakaya Fletcher S, James EA, Liu M, Barrett JC, Withycombe J, Matthews DC, Epstein MS, Hughes RJ, Pratt KP; Personalized Approaches to Therapies for Hemophilia (PATH) Study Investigators.

Blood. 2015 Aug 13;126(7):895-904. doi: 10.1182/blood-2014-09-599365. Epub 2015 Jan 23.


Six amino acid residues in a 1200 Å2 interface mediate binding of factor VIII to an IgG4κ inhibitory antibody.

Lin JC, Ettinger RA, Schuman JT, Zhang AH, Wamiq-Adhami M, Nguyen PC, Nakaya-Fletcher SM, Puranik K, Thompson AR, Pratt KP.

PLoS One. 2015 Jan 23;10(1):e0116577. doi: 10.1371/journal.pone.0116577. eCollection 2015.


Engineered antigen-specific human regulatory T cells: immunosuppression of FVIII-specific T- and B-cell responses.

Kim YC, Zhang AH, Su Y, Rieder SA, Rossi RJ, Ettinger RA, Pratt KP, Shevach EM, Scott DW.

Blood. 2015 Feb 12;125(7):1107-15. doi: 10.1182/blood-2014-04-566786. Epub 2014 Dec 10.


High-resolution mapping of epitopes on the C2 domain of factor VIII by analysis of point mutants using surface plasmon resonance.

Nguyen PC, Lewis KB, Ettinger RA, Schuman JT, Lin JC, Healey JF, Meeks SL, Lollar P, Pratt KP.

Blood. 2014 Apr 24;123(17):2732-9. doi: 10.1182/blood-2013-09-527275. Epub 2014 Mar 3.


Phenotypes of allo- and autoimmune antibody responses to FVIII characterized by surface plasmon resonance.

Lewis KB, Hughes RJ, Epstein MS, Josephson NC, Kempton CL, Kessler CM, Key NS, Howard TE, Kruse-Jarres R, Lusher JM, Walsh CE, Watts RG, Ettinger RA, Pratt KP; PATH (Personalized Alternative Therapies for Haemophilia) Study Investigators.

PLoS One. 2013 May 8;8(5):e61120. doi: 10.1371/journal.pone.0061120. Print 2013.


BB rat Gimap gene expression in sorted lymphoid T and B cells.

Moralejo DH, Fuller JM, Rutledge EA, Van Yserloo B, Ettinger RA, Jensen R, Osborne W, Kwitek A, Lernmark A.

Life Sci. 2011 Nov 7;89(19-20):748-54. doi: 10.1016/j.lfs.2011.08.016. Epub 2011 Sep 10.


T-cell responses in two unrelated hemophilia A inhibitor subjects include an epitope at the factor VIII R593C missense site.

James EA, van Haren SD, Ettinger RA, Fijnvandraat K, Liberman JA, Kwok WW, Voorberg J, Pratt KP.

J Thromb Haemost. 2011 Apr;9(4):689-99. doi: 10.1111/j.1538-7836.2011.04202.x.


HLA-DR-restricted T-cell responses to factor VIII epitopes in a mild haemophilia A family with missense substitution A2201P.

Ettinger RA, James EA, Kwok WW, Thompson AR, Pratt KP.

Haemophilia. 2010 May;16(102):44-55. doi: 10.1111/j.1365-2516.2008.01905.x.


Lineages of human T-cell clones, including T helper 17/T helper 1 cells, isolated at different stages of anti-factor VIII immune responses.

Ettinger RA, James EA, Kwok WW, Thompson AR, Pratt KP.

Blood. 2009 Aug 13;114(7):1423-8. doi: 10.1182/blood-2009-01-200725. Epub 2009 Jun 23.


Sequence variation and expression of the Gimap gene family in the BB rat.

Rutledge EA, Fuller JM, Van Yserloo B, Moralejo DH, Ettinger RA, Gaur P, Hoehna JL, Peterson MR, Jensen R, Kwitek AE, Lernmark A.

Exp Diabetes Res. 2009;2009:835650. doi: 10.1155/2009/835650. Epub 2009 May 3.


Open reading frame sequencing and structure-based alignment of polypeptides encoded by RT1-Bb, RT1-Ba, RT1-Db, and RT1-Da alleles.

Ettinger RA, Moustakas AK, Lobaton SD.

Immunogenetics. 2004 Nov;56(8):585-96. Epub 2004 Oct 23.


Transgenic rescue demonstrates involvement of the Ian5 gene in T cell development in the rat.

Michalkiewicz M, Michalkiewicz T, Ettinger RA, Rutledge EA, Fuller JM, Moralejo DH, Van Yserloo B, MacMurray AJ, Kwitek AE, Jacob HJ, Lander ES, Lernmark A.

Physiol Genomics. 2004 Oct 4;19(2):228-32. Epub 2004 Aug 24.


Lymphopenia in the BB rat model of type 1 diabetes is due to a mutation in a novel immune-associated nucleotide (Ian)-related gene.

MacMurray AJ, Moralejo DH, Kwitek AE, Rutledge EA, Van Yserloo B, Gohlke P, Speros SJ, Snyder B, Schaefer J, Bieg S, Jiang J, Ettinger RA, Fuller J, Daniels TL, Pettersson A, Orlebeke K, Birren B, Jacob HJ, Lander ES, Lernmark A.

Genome Res. 2002 Jul;12(7):1029-39.


Mutational analysis of critical residues determining antigen presentation and activation of HLA-DQ0602 restricted T-cell clones.

Reichstetter S, Papadopoulos GK, Moustakas AK, Swanson E, Liu AW, Beheray S, Ettinger RA, Nepom GT, Kwok WW.

Hum Immunol. 2002 Mar;63(3):185-93.


Distinct T cell interactions with HLA class II tetramers characterize a spectrum of TCR affinities in the human antigen-specific T cell response.

Reichstetter S, Ettinger RA, Liu AW, Gebe JA, Nepom GT, Kwok WW.

J Immunol. 2000 Dec 15;165(12):6994-8.


The vitamin D3 hydroxylase-associated protein is a propionamide-metabolizing amidase enzyme.

Ettinger RA, DeLuca HF.

Arch Biochem Biophys. 1995 Jan 10;316(1):14-9.


cDNA cloning and characterization of a vitamin D3 hydroxylase-associated protein.

Ettinger RA, Ismail R, DeLuca HF.

J Biol Chem. 1994 Jan 7;269(1):176-82.


Immunopurified 25-hydroxyvitamin D 1 alpha-hydroxylase and 1,25-dihydroxyvitamin D 24-hydroxylase are closely related but distinct enzymes.

Burgos-Trinidad M, Ismail R, Ettinger RA, Prahl JM, DeLuca HF.

J Biol Chem. 1992 Feb 15;267(5):3498-505.


Selective adsorption of apoferritin on immobilized Fe(III): demonstration of Fe(III) binding sites.

Boyer RF, Generous SM, Nieuwenhuis TJ, Ettinger RA.

Biotechnol Appl Biochem. 1990 Feb;12(1):79-84.


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