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Items: 1 to 50 of 81

1.

Evaluation of CD33 as a genetic risk factor for Alzheimer's disease.

Estus S, Shaw BC, Devanney N, Katsumata Y, Press EE, Fardo DW.

Acta Neuropathol. 2019 Aug;138(2):187-199. doi: 10.1007/s00401-019-02000-4. Epub 2019 Apr 4. Review.

PMID:
30949760
2.

Translating Alzheimer's disease-associated polymorphisms into functional candidates: a survey of IGAP genes and SNPs.

Katsumata Y, Nelson PT, Estus S; Alzheimer's Disease Neuroimaging Initiative (ADNI), Fardo DW.

Neurobiol Aging. 2019 Feb;74:135-146. doi: 10.1016/j.neurobiolaging.2018.10.017. Epub 2018 Oct 23.

PMID:
30448613
3.

Alzheimer's Disease Genetics and ABCA7 Splicing.

Vasquez JB, Simpson JF, Harpole R, Estus S.

J Alzheimers Dis. 2017;59(2):633-641. doi: 10.3233/JAD-170872.

4.

Predominant expression of Alzheimer's disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts.

De Rossi P, Buggia-Prévot V, Clayton BL, Vasquez JB, van Sanford C, Andrew RJ, Lesnick R, Botté A, Deyts C, Salem S, Rao E, Rice RC, Parent A, Kar S, Popko B, Pytel P, Estus S, Thinakaran G.

Mol Neurodegener. 2016 Aug 3;11(1):59. doi: 10.1186/s13024-016-0124-1.

5.

Identification of plexin A4 as a novel clusterin receptor links two Alzheimer's disease risk genes.

Kang SS, Kurti A, Wojtas A, Baker KE, Liu CC, Kanekiyo T, Deming Y, Cruchaga C, Estus S, Bu G, Fryer JD.

Hum Mol Genet. 2016 Aug 15;25(16):3467-3475. doi: 10.1093/hmg/ddw188. Epub 2016 Jul 4.

6.

Association Between Overall and Mentholated Cigarette Smoking With Headache in a Nationally Representative Sample.

Gan WQ, Estus S, Smith JH.

Headache. 2016 Mar;56(3):511-8. doi: 10.1111/head.12778. Epub 2016 Mar 1.

PMID:
26926358
7.

Looking for reward in all the wrong places: dopamine receptor gene polymorphisms indirectly affect aggression through sensation-seeking.

Chester DS, DeWall CN, Derefinko KJ, Estus S, Lynam DR, Peters JR, Jiang Y.

Soc Neurosci. 2016 Oct;11(5):487-94. doi: 10.1080/17470919.2015.1119191. Epub 2015 Dec 7.

8.

Genetics ignite focus on microglial inflammation in Alzheimer's disease.

Malik M, Parikh I, Vasquez JB, Smith C, Tai L, Bu G, LaDu MJ, Fardo DW, Rebeck GW, Estus S.

Mol Neurodegener. 2015 Oct 5;10:52. doi: 10.1186/s13024-015-0048-1. Review.

9.

Genetics of CD33 in Alzheimer's disease and acute myeloid leukemia.

Malik M, Chiles J 3rd, Xi HS, Medway C, Simpson J, Potluri S, Howard D, Liang Y, Paumi CM, Mukherjee S, Crane P, Younkin S, Fardo DW, Estus S.

Hum Mol Genet. 2015 Jun 15;24(12):3557-70. doi: 10.1093/hmg/ddv092. Epub 2015 Mar 11.

10.

Monoamine oxidase A (MAOA) genotype predicts greater aggression through impulsive reactivity to negative affect.

Chester DS, DeWall CN, Derefinko KJ, Estus S, Peters JR, Lynam DR, Jiang Y.

Behav Brain Res. 2015 Apr 15;283:97-101. doi: 10.1016/j.bbr.2015.01.034. Epub 2015 Jan 28.

11.

Longitudinal trajectories of cholesterol from midlife through late life according to apolipoprotein E allele status.

Downer B, Estus S, Katsumata Y, Fardo DW.

Int J Environ Res Public Health. 2014 Oct 16;11(10):10663-93. doi: 10.3390/ijerph111010663.

12.

Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease.

Liu CC, Tsai CW, Deak F, Rogers J, Penuliar M, Sung YM, Maher JN, Fu Y, Li X, Xu H, Estus S, Hoe HS, Fryer JD, Kanekiyo T, Bu G.

Neuron. 2014 Oct 1;84(1):63-77. doi: 10.1016/j.neuron.2014.08.048. Epub 2014 Sep 18.

13.

An intronic PICALM polymorphism, rs588076, is associated with allelic expression of a PICALM isoform.

Parikh I, Medway C, Younkin S, Fardo DW, Estus S.

Mol Neurodegener. 2014 Aug 29;9:32. doi: 10.1186/1750-1326-9-32.

14.

White matter integrity is associated with cerebrospinal fluid markers of Alzheimer's disease in normal adults.

Gold BT, Zhu Z, Brown CA, Andersen AH, LaDu MJ, Tai L, Jicha GA, Kryscio RJ, Estus S, Nelson PT, Scheff SW, Abner E, Schmitt FA, Van Eldik LJ, Smith CD.

Neurobiol Aging. 2014 Oct;35(10):2263-71. doi: 10.1016/j.neurobiolaging.2014.04.030. Epub 2014 May 2.

15.

ABCC9 gene polymorphism is associated with hippocampal sclerosis of aging pathology.

Nelson PT, Estus S, Abner EL, Parikh I, Malik M, Neltner JH, Ighodaro E, Wang WX, Wilfred BR, Wang LS, Kukull WA, Nandakumar K, Farman ML, Poon WW, Corrada MM, Kawas CH, Cribbs DH, Bennett DA, Schneider JA, Larson EB, Crane PK, Valladares O, Schmitt FA, Kryscio RJ, Jicha GA, Smith CD, Scheff SW, Sonnen JA, Haines JL, Pericak-Vance MA, Mayeux R, Farrer LA, Van Eldik LJ, Horbinski C, Green RC, Gearing M, Poon LW, Kramer PL, Woltjer RL, Montine TJ, Partch AB, Rajic AJ, Richmire K, Monsell SE; Alzheimer’ Disease Genetic Consortium, Schellenberg GD, Fardo DW.

Acta Neuropathol. 2014;127(6):825-43. doi: 10.1007/s00401-014-1282-2. Epub 2014 Apr 27.

16.

Genetics of PICALM expression and Alzheimer's disease.

Parikh I, Fardo DW, Estus S.

PLoS One. 2014 Mar 11;9(3):e91242. doi: 10.1371/journal.pone.0091242. eCollection 2014.

17.

Soluble apoE/Aβ complex: mechanism and therapeutic target for APOE4-induced AD risk.

Tai LM, Mehra S, Shete V, Estus S, Rebeck GW, Bu G, LaDu MJ.

Mol Neurodegener. 2014 Jan 4;9:2. doi: 10.1186/1750-1326-9-2. Review.

18.

ABCA7 expression is associated with Alzheimer's disease polymorphism and disease status.

Vasquez JB, Fardo DW, Estus S.

Neurosci Lett. 2013 Nov 27;556:58-62. doi: 10.1016/j.neulet.2013.09.058. Epub 2013 Oct 18.

19.

CD33 Alzheimer's risk-altering polymorphism, CD33 expression, and exon 2 splicing.

Malik M, Simpson JF, Parikh I, Wilfred BR, Fardo DW, Nelson PT, Estus S.

J Neurosci. 2013 Aug 14;33(33):13320-5. doi: 10.1523/JNEUROSCI.1224-13.2013.

20.

APOE-ε2 and APOE-ε4 correlate with increased amyloid accumulation in cerebral vasculature.

Nelson PT, Pious NM, Jicha GA, Wilcock DM, Fardo DW, Estus S, Rebeck GW.

J Neuropathol Exp Neurol. 2013 Jul;72(7):708-15. doi: 10.1097/NEN.0b013e31829a25b9.

21.

Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples.

Tai LM, Bilousova T, Jungbauer L, Roeske SK, Youmans KL, Yu C, Poon WW, Cornwell LB, Miller CA, Vinters HV, Van Eldik LJ, Fardo DW, Estus S, Bu G, Gylys KH, Ladu MJ.

J Biol Chem. 2013 Feb 22;288(8):5914-26. doi: 10.1074/jbc.M112.442103. Epub 2013 Jan 4.

22.

APOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease.

Youmans KL, Tai LM, Nwabuisi-Heath E, Jungbauer L, Kanekiyo T, Gan M, Kim J, Eimer WA, Estus S, Rebeck GW, Weeber EJ, Bu G, Yu C, Ladu MJ.

J Biol Chem. 2012 Dec 7;287(50):41774-86. doi: 10.1074/jbc.M112.407957. Epub 2012 Oct 11.

23.

Genetics of clusterin isoform expression and Alzheimer's disease risk.

Ling IF, Bhongsatiern J, Simpson JF, Fardo DW, Estus S.

PLoS One. 2012;7(4):e33923. doi: 10.1371/journal.pone.0033923. Epub 2012 Apr 10.

24.

BACE2 expression increases in human neurodegenerative disease.

Holler CJ, Webb RL, Laux AL, Beckett TL, Niedowicz DM, Ahmed RR, Liu Y, Simmons CR, Dowling AL, Spinelli A, Khurgel M, Estus S, Head E, Hersh LB, Murphy MP.

Am J Pathol. 2012 Jan;180(1):337-50. doi: 10.1016/j.ajpath.2011.09.034. Epub 2011 Nov 7.

25.
26.

FBN1 isoform expression varies in a tissue and development-specific fashion.

Burchett ME, Ling IF, Estus S.

Biochem Biophys Res Commun. 2011 Jul 29;411(2):323-8. doi: 10.1016/j.bbrc.2011.06.140. Epub 2011 Jun 25.

27.

Rheumatoid arthritis-associated polymorphisms are not protective against Alzheimer's disease.

Simmons CR, Zou F, Younkin SG, Estus S.

Mol Neurodegener. 2011 May 19;6:33. doi: 10.1186/1750-1326-6-33.

28.

Prion protein expression and functional importance in skeletal muscle.

Smith JD, Moylan JS, Hardin BJ, Chambers MA, Estus S, Telling GC, Reid MB.

Antioxid Redox Signal. 2011 Nov 1;15(9):2465-75. doi: 10.1089/ars.2011.3945. Epub 2011 Jun 8.

29.
30.

Expression and regulation of a low-density lipoprotein receptor exon 12 splice variant.

Ling IF, Gopalraj RK, Simpson JF, Estus S.

J Neurochem. 2010 Nov;115(3):614-24. doi: 10.1111/j.1471-4159.2010.06972.x. Epub 2010 Sep 28.

31.

Role of SFRS13A in low-density lipoprotein receptor splicing.

Ling IF, Estus S.

Hum Mutat. 2010 Jun;31(6):702-9. doi: 10.1002/humu.21244.

32.

Expression of SORL1 and a novel SORL1 splice variant in normal and Alzheimers disease brain.

Grear KE, Ling IF, Simpson JF, Furman JL, Simmons CR, Peterson SL, Schmitt FA, Markesbery WR, Liu Q, Crook JE, Younkin SG, Bu G, Estus S.

Mol Neurodegener. 2009 Nov 4;4:46. doi: 10.1186/1750-1326-4-46.

33.

LRP1 shedding in human brain: roles of ADAM10 and ADAM17.

Liu Q, Zhang J, Tran H, Verbeek MM, Reiss K, Estus S, Bu G.

Mol Neurodegener. 2009 Apr 16;4:17. doi: 10.1186/1750-1326-4-17.

34.

Sex-dependent association of a common low-density lipoprotein receptor polymorphism with RNA splicing efficiency in the brain and Alzheimer's disease.

Zou F, Gopalraj RK, Lok J, Zhu H, Ling IF, Simpson JF, Tucker HM, Kelly JF, Younkin SG, Dickson DW, Petersen RC, Graff-Radford NR, Bennett DA, Crook JE, Younkin SG, Estus S.

Hum Mol Genet. 2008 Apr 1;17(7):929-35. Epub 2007 Dec 8.

35.

A common polymorphism decreases low-density lipoprotein receptor exon 12 splicing efficiency and associates with increased cholesterol.

Zhu H, Tucker HM, Grear KE, Simpson JF, Manning AK, Cupples LA, Estus S.

Hum Mol Genet. 2007 Jul 15;16(14):1765-72. Epub 2007 May 21.

36.

Adriamycin-mediated nitration of manganese superoxide dismutase in the central nervous system: insight into the mechanism of chemobrain.

Tangpong J, Cole MP, Sultana R, Estus S, Vore M, St Clair W, Ratanachaiyavong S, St Clair DK, Butterfield DA.

J Neurochem. 2007 Jan;100(1):191-201.

37.

Lack of association of hepatic lipase polymorphisms with late-onset Alzheimer's disease.

Zhu H, Taylor JW, Bennett DA, Younkin SG, Estus S.

Neurobiol Aging. 2008 May;29(5):793-4. Epub 2006 Dec 18.

38.

The generation and function of soluble apoE receptors in the CNS.

Rebeck GW, LaDu MJ, Estus S, Bu G, Weeber EJ.

Mol Neurodegener. 2006 Oct 24;1:15.

39.

Adriamycin-induced, TNF-alpha-mediated central nervous system toxicity.

Tangpong J, Cole MP, Sultana R, Joshi G, Estus S, Vore M, St Clair W, Ratanachaiyavong S, St Clair DK, Butterfield DA.

Neurobiol Dis. 2006 Jul;23(1):127-39. Epub 2006 May 11.

PMID:
16697651
40.

Free radical mediated oxidative stress and toxic side effects in brain induced by the anti cancer drug adriamycin: insight into chemobrain.

Joshi G, Sultana R, Tangpong J, Cole MP, St Clair DK, Vore M, Estus S, Butterfield DA.

Free Radic Res. 2005 Nov;39(11):1147-54.

PMID:
16298740
41.

Lack of genetic association of cholesteryl ester transfer protein polymorphisms with late onset Alzheimers disease.

Zhu H, Gopalraj RK, Kelly JF, Bennett DA, Estus S.

Neurosci Lett. 2005 Jun 10-17;381(1-2):36-41. Epub 2005 Feb 17.

PMID:
15882786
42.

Elevated amyloid beta protein (Abeta42) and late onset Alzheimer's disease are associated with single nucleotide polymorphisms in the urokinase-type plasminogen activator gene.

Ertekin-Taner N, Ronald J, Feuk L, Prince J, Tucker M, Younkin L, Hella M, Jain S, Hackett A, Scanlin L, Kelly J, Kihiko-Ehman M, Neltner M, Hersh L, Kindy M, Markesbery W, Hutton M, de Andrade M, Petersen RC, Graff-Radford N, Estus S, Brookes AJ, Younkin SG.

Hum Mol Genet. 2005 Feb 1;14(3):447-60. Epub 2004 Dec 22.

PMID:
15615772
43.

Genetic association of low density lipoprotein receptor and Alzheimer's disease.

Gopalraj RK, Zhu H, Kelly JF, Mendiondo M, Pulliam JF, Bennett DA, Estus S.

Neurobiol Aging. 2005 Jan;26(1):1-7.

PMID:
15585340
44.

Plasmin deficiency does not alter endogenous murine amyloid beta levels in mice.

Tucker HM, Simpson J, Kihiko-Ehmann M, Younkin LH, McGillis JP, Younkin SG, Degen JL, Estus S.

Neurosci Lett. 2004 Sep 30;368(3):285-9.

PMID:
15364412
45.
46.

Live discussion: Amyloid-beta degradation: the forgotten half of Alzheimer's disease. 12 September 2002.

Whitaker C, Eckman C, Almeida C, Feinstein D, Atwood C, Eckman E, Crutcher K, Hersh L, Leissring M, LaVoie M, Ertekin-Taner N, Shapiro P, Takahashi R, Yamin R, Mansourian S, Estus S, Lesné S, Turner T, Farris W, Stroebel G.

J Alzheimers Dis. 2003 Dec;5(6):491-7. No abstract available.

PMID:
14765518
47.

4-hydroxynonenal contributes to NGF withdrawal-induced neuronal apoptosis.

Bruckner SR, Perry G, Estus S.

J Neurochem. 2003 May;85(4):999-1005.

48.

Glutamate regulates caveolin expression in rat hippocampal neurons.

Bu J, Bruckner SR, Sengoku T, Geddes JW, Estus S.

J Neurosci Res. 2003 Apr 15;72(2):185-90.

PMID:
12671992
49.

Evolution and the scientific method.

Tucker HM, Estus S.

Neurobiol Aging. 2002 Nov-Dec;23(6):1093-5. No abstract available.

PMID:
12470808
50.

JNK3 contributes to c-jun induction and apoptosis in 4-hydroxynonenal-treated sympathetic neurons.

Bruckner SR, Estus S.

J Neurosci Res. 2002 Dec 1;70(5):665-70.

PMID:
12424734

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