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Items: 12


Specificity of the Redox Complex between Cytochrome P450 24A1 and Adrenodoxin Relies on Carbon-25 Hydroxylation of Vitamin-D Substrate.

Kumar A, Estrada DF.

Drug Metab Dispos. 2019 Sep;47(9):974-982. doi: 10.1124/dmd.119.087759. Epub 2019 Jul 9.


The cytochrome P450 24A1 interaction with adrenodoxin relies on multiple recognition sites that vary among species.

Estrada DF.

J Biol Chem. 2018 Mar 16;293(11):4167-4179. doi: 10.1074/jbc.RA117.001145. Epub 2018 Jan 25.


Structural insights into the function of steroidogenic cytochrome P450 17A1.

Yadav R, Petrunak EM, Estrada DF, Scott EE.

Mol Cell Endocrinol. 2017 Feb 5;441:68-75. doi: 10.1016/j.mce.2016.08.035. Epub 2016 Aug 24. Review.


The Role of Protein-Protein and Protein-Membrane Interactions on P450 Function.

Scott EE, Wolf CR, Otyepka M, Humphreys SC, Reed JR, Henderson CJ, McLaughlin LA, Paloncýová M, Navrátilová V, Berka K, Anzenbacher P, Dahal UP, Barnaba C, Brozik JA, Jones JP, Estrada DF, Laurence JS, Park JW, Backes WL.

Drug Metab Dispos. 2016 Apr;44(4):576-90. doi: 10.1124/dmd.115.068569. Epub 2016 Feb 5. Review.


Cytochrome P450 17A1 Interactions with the FMN Domain of Its Reductase as Characterized by NMR.

Estrada DF, Laurence JS, Scott EE.

J Biol Chem. 2016 Feb 19;291(8):3990-4003. doi: 10.1074/jbc.M115.677294. Epub 2015 Dec 30.


Human cytochrome P450 17A1 conformational selection: modulation by ligand and cytochrome b5.

Estrada DF, Skinner AL, Laurence JS, Scott EE.

J Biol Chem. 2014 May 16;289(20):14310-20. doi: 10.1074/jbc.M114.560144. Epub 2014 Mar 26.


Correlating structure and function of drug-metabolizing enzymes: progress and ongoing challenges.

Johnson EF, Connick JP, Reed JR, Backes WL, Desai MC, Xu L, Estrada DF, Laurence JS, Scott EE.

Drug Metab Dispos. 2014 Jan;42(1):9-22. doi: 10.1124/dmd.113.054627. Epub 2013 Oct 15. Review.


Substrate-modulated cytochrome P450 17A1 and cytochrome b5 interactions revealed by NMR.

Estrada DF, Laurence JS, Scott EE.

J Biol Chem. 2013 Jun 7;288(23):17008-18. doi: 10.1074/jbc.M113.468926. Epub 2013 Apr 25.


The Structure of the Hantavirus Zinc Finger Domain is Conserved and Represents the Only Natively Folded Region of the Gn Cytoplasmic Tail.

Estrada DF, Conner M, Jeor SC, Guzman RN.

Front Microbiol. 2011 Dec 21;2:251. doi: 10.3389/fmicb.2011.00251. eCollection 2011.


Structural characterization of the Crimean-Congo hemorrhagic fever virus Gn tail provides insight into virus assembly.

Estrada DF, De Guzman RN.

J Biol Chem. 2011 Jun 17;286(24):21678-86. doi: 10.1074/jbc.M110.216515. Epub 2011 Apr 20.


The Hantavirus Glycoprotein G1 Tail Contains Dual CCHC-type Classical Zinc Fingers.

Estrada DF, Boudreaux DM, Zhong D, St Jeor SC, De Guzman RN.

J Biol Chem. 2009 Mar 27;284(13):8654-60. doi: 10.1074/jbc.M808081200. Epub 2009 Jan 29.


NMR structure of the N-terminal coiled coil domain of the Andes hantavirus nucleocapsid protein.

Wang Y, Boudreaux DM, Estrada DF, Egan CW, St Jeor SC, De Guzman RN.

J Biol Chem. 2008 Oct 17;283(42):28297-304. doi: 10.1074/jbc.M804869200. Epub 2008 Aug 7.

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