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American Thoracic Society 2019 Pediatric Core Curriculum.

Moore PE, Boyer D, Perkins R, Katz ES, Castro-Codesal ML, MacLean JE, Akil N, Esther CR Jr, Kaslow J, Lewis TC, Krone KA, Quizon A, Simpson R, Benscoter D, Spielberg DR, Melicoff E, Kuklinski CA, Blatter JA, Dy J, Rettig JS, Horani A, Gross J.

Pediatr Pulmonol. 2019 Aug 27. doi: 10.1002/ppul.24482. [Epub ahead of print] Review.


Identifying Biomarkers in Pediatric Rare Lung Disease: chILD Grows Up.

Vece TJ, Esther CR.

Am J Respir Crit Care Med. 2019 Aug 27. doi: 10.1164/rccm.201908-1594ED. [Epub ahead of print] No abstract available.


Chronic E-Cigarette Use Increases Neutrophil Elastase and Matrix Metalloprotease Levels in the Lung.

Ghosh A, Coakley RD, Ghio AJ, Muhlebach MS, Esther CR Jr, Alexis NE, Tarran R.

Am J Respir Crit Care Med. 2019 Aug 7. doi: 10.1164/rccm.201903-0615OC. [Epub ahead of print]


Highlights from the 2018 North American cystic fibrosis conference.

Martiniano SL, Daines CL, Dellon EP, Esther CR Jr, Muhlebach MS, Ong T, Rabinowitz EC, Toprak D, Zemanick ET.

Pediatr Pulmonol. 2019 Jul;54(7):941-948. doi: 10.1002/ppul.24356. Epub 2019 May 15. Review.


Use of inhaled imipenem/cilastatin in pediatric patients with cystic fibrosis: A case series.

Jones LA, Doucette L, Dellon EP, Esther CR, McKinzie CJ.

J Cyst Fibros. 2019 Jul;18(4):e42-e44. doi: 10.1016/j.jcf.2019.04.017. Epub 2019 May 3.


Mucus accumulation in the lungs precedes structural changes and infection in children with cystic fibrosis.

Esther CR Jr, Muhlebach MS, Ehre C, Hill DB, Wolfgang MC, Kesimer M, Ramsey KA, Markovetz MR, Garbarine IC, Forest MG, Seim I, Zorn B, Morrison CB, Delion MF, Thelin WR, Villalon D, Sabater JR, Turkovic L, Ranganathan S, Stick SM, Boucher RC.

Sci Transl Med. 2019 Apr 3;11(486). pii: eaav3488. doi: 10.1126/scitranslmed.aav3488.


Persistent Wheeze in Infants: A Guide for General Pediatricians.

Yu Y, Esther CR Jr, Ren CL, Loughlin C.

Pediatr Ann. 2019 Mar 1;48(3):e110-e114. doi: 10.3928/19382359-20190222-02.


An Improved Inhaled Mucolytic to Treat Airway Muco-obstructive Diseases.

Ehre C, Rushton ZL, Wang B, Hothem LN, Morrison CB, Fontana NC, Markovetz MR, Delion MF, Kato T, Villalon D, Thelin WR, Esther CR Jr, Hill DB, Grubb BR, Livraghi-Butrico A, Donaldson SH, Boucher RC.

Am J Respir Crit Care Med. 2019 Jan 15;199(2):171-180. doi: 10.1164/rccm.201802-0245OC.


Use of telavancin in adolescent patients with cystic fibrosis and prior intolerance to vancomycin: A case series.

Bernstein AT, Leigh MW, Goralski JL, Esther CR Jr, McKinzie CJ.

J Cyst Fibros. 2018 Nov;17(6):e48-e50. doi: 10.1016/j.jcf.2018.08.003. Epub 2018 Aug 28.


Iron concentration in exhaled breath condensate decreases in ever-smokers and COPD patients.

Ghio AJ, Soukup JM, McGee J, Madden MC, Esther CR.

J Breath Res. 2018 Aug 21;12(4):046009. doi: 10.1088/1752-7163/aad825.


Tracheostomy in children: Epidemiology and clinical outcomes.

Sanders CD, Guimbellot JS, Muhlebach MS, Lin FC, Gilligan P, Esther CR Jr.

Pediatr Pulmonol. 2018 Sep;53(9):1269-1275. doi: 10.1002/ppul.24071. Epub 2018 Jul 3.


Measured fetal and neonatal exposure to Lumacaftor and Ivacaftor during pregnancy and while breastfeeding.

Trimble A, McKinzie C, Terrell M, Stringer E, Esther CR Jr.

J Cyst Fibros. 2018 Nov;17(6):779-782. doi: 10.1016/j.jcf.2018.05.009. Epub 2018 Jun 1.


Highlights from the 2017 North American Cystic Fibrosis Conference.

Martiniano SL, Toprak D, Ong T, Zemanick ET, Daines CL, Muhlebach MS, Esther CR Jr, Dellon EP.

Pediatr Pulmonol. 2018 Jul;53(7):979-986. doi: 10.1002/ppul.24000. Epub 2018 Apr 16. Review.


Initial acquisition and succession of the cystic fibrosis lung microbiome is associated with disease progression in infants and preschool children.

Muhlebach MS, Zorn BT, Esther CR, Hatch JE, Murray CP, Turkovic L, Ranganathan SC, Boucher RC, Stick SM, Wolfgang MC.

PLoS Pathog. 2018 Jan 18;14(1):e1006798. doi: 10.1371/journal.ppat.1006798. eCollection 2018 Jan.


Transition and post-transition metals in exhaled breath condensate.

Ghio AJ, Madden MC, Esther CR.

J Breath Res. 2018 Feb 7;12(2):027112. doi: 10.1088/1752-7163/aaa214. Review.


Continuous vancomycin in a pediatric cystic fibrosis patient.

McKinzie CJ, Esther CR, Vece TJ.

Pediatr Pulmonol. 2018 Jan;53(1):E4-E5. doi: 10.1002/ppul.23844. Epub 2017 Nov 29.


Loss of β Epithelial Sodium Channel Function in Meibomian Glands Produces Pseudohypoaldosteronism 1-Like Ocular Disease in Mice.

Yu D, Saini Y, Chen G, Ghio AJ, Dang H, Burns KA, Wang Y, Davis RM, Randell SH, Esther CR Jr, Paulsen F, Boucher RC.

Am J Pathol. 2018 Jan;188(1):95-110. doi: 10.1016/j.ajpath.2017.09.016. Epub 2017 Oct 26.


Lung disease phenotypes caused by overexpression of combinations of α-, β-, and γ-subunits of the epithelial sodium channel in mouse airways.

Livraghi-Butrico A, Wilkinson KJ, Volmer AS, Gilmore RC, Rogers TD, Caldwell RA, Burns KA, Esther CR Jr, Mall MA, Boucher RC, O'Neal WK, Grubb BR.

Am J Physiol Lung Cell Mol Physiol. 2018 Feb 1;314(2):L318-L331. doi: 10.1152/ajplung.00382.2017. Epub 2017 Oct 26.


Mapping targetable inflammation and outcomes with cystic fibrosis biomarkers.

Giddings O, Esther CR Jr.

Pediatr Pulmonol. 2017 Nov;52(S48):S21-S28. doi: 10.1002/ppul.23768. Epub 2017 Jul 17. Review.


Highlights from the 2016 North American Cystic Fibrosis Conference.

Zemanick ET, Daines CL, Dellon EP, Esther CR Jr, Kinghorn B, Ong T, Muhlebach MS.

Pediatr Pulmonol. 2017 Aug;52(8):1103-1110. doi: 10.1002/ppul.23707. Epub 2017 Jul 11. Review.


Outcomes associated with antibiotic regimens for treatment of Mycobacterium abscessus in cystic fibrosis patients.

DaCosta A, Jordan CL, Giddings O, Lin FC, Gilligan P, Esther CR Jr.

J Cyst Fibros. 2017 Jul;16(4):483-487. doi: 10.1016/j.jcf.2017.04.013. Epub 2017 May 8.


Sialic acid-to-urea ratio as a measure of airway surface hydration.

Esther CR Jr, Hill DB, Button B, Shi S, Jania C, Duncan EA, Doerschuk CM, Chen G, Ranganathan S, Stick SM, Boucher RC.

Am J Physiol Lung Cell Mol Physiol. 2017 Mar 1;312(3):L398-L404. doi: 10.1152/ajplung.00398.2016. Epub 2017 Jan 6.


Emergence and spread of a human-transmissible multidrug-resistant nontuberculous mycobacterium.

Bryant JM, Grogono DM, Rodriguez-Rincon D, Everall I, Brown KP, Moreno P, Verma D, Hill E, Drijkoningen J, Gilligan P, Esther CR, Noone PG, Giddings O, Bell SC, Thomson R, Wainwright CE, Coulter C, Pandey S, Wood ME, Stockwell RE, Ramsay KA, Sherrard LJ, Kidd TJ, Jabbour N, Johnson GR, Knibbs LD, Morawska L, Sly PD, Jones A, Bilton D, Laurenson I, Ruddy M, Bourke S, Bowler IC, Chapman SJ, Clayton A, Cullen M, Daniels T, Dempsey O, Denton M, Desai M, Drew RJ, Edenborough F, Evans J, Folb J, Humphrey H, Isalska B, Jensen-Fangel S, Jönsson B, Jones AM, Katzenstein TL, Lillebaek T, MacGregor G, Mayell S, Millar M, Modha D, Nash EF, O'Brien C, O'Brien D, Ohri C, Pao CS, Peckham D, Perrin F, Perry A, Pressler T, Prtak L, Qvist T, Robb A, Rodgers H, Schaffer K, Shafi N, van Ingen J, Walshaw M, Watson D, West N, Whitehouse J, Haworth CS, Harris SR, Ordway D, Parkhill J, Floto RA.

Science. 2016 Nov 11;354(6313):751-757. doi: 10.1126/science.aaf8156.


Metabolomic biomarkers predictive of early structural lung disease in cystic fibrosis.

Esther CR Jr, Turkovic L, Rosenow T, Muhlebach MS, Boucher RC, Ranganathan S, Stick SM; AREST CF.

Eur Respir J. 2016 Dec;48(6):1612-1621. doi: 10.1183/13993003.00524-2016. Epub 2016 Nov 11.


Diagnostic Evaluation of Infants with Recurrent or Persistent Wheezing.

Boyer D, Barsky E, Papantonakis CM, Pittman J, Ren CL, Esther CR Jr, Wilson KC, Thomson CC.

Ann Am Thorac Soc. 2016 Nov;13(11):2057-2059. No abstract available.


Efficacy of lumacaftor-ivacaftor for the treatment of cystic fibrosis patients homozygous for the F508del-CFTR mutation.

Cholon DM, Esther CR Jr, Gentzsch M.

Expert Rev Precis Med Drug Dev. 2016;1(3):235-243. Epub 2016 Apr 22.


Official American Thoracic Society Clinical Practice Guidelines: Diagnostic Evaluation of Infants with Recurrent or Persistent Wheezing.

Ren CL, Esther CR Jr, Debley JS, Sockrider M, Yilmaz O, Amin N, Bazzy-Asaad A, Davis SD, Durand M, Ewig JM, Yuksel H, Lombardi E, Noah TL, Radford P, Ranganathan S, Teper A, Weinberger M, Brozek J, Wilson KC; ATS Ad Hoc Committee on Infants with Recurrent or Persistent Wheezing.

Am J Respir Crit Care Med. 2016 Aug 1;194(3):356-73. doi: 10.1164/rccm.201604-0694ST.


Highlights from the 2015 North American Cystic Fibrosis Conference.

Zemanick ET, Ong T, Daines CL, Dellon EP, Muhlebach MS, Esther CR Jr.

Pediatr Pulmonol. 2016 Jun;51(6):650-7. doi: 10.1002/ppul.23441. Epub 2016 Apr 13.


Clinical outcomes in cystic fibrosis patients with Trichosporon respiratory infection.

Esther CR Jr, Plongla R, Kerr A, Lin FC, Gilligan P.

J Cyst Fibros. 2016 Sep;15(5):e45-9. doi: 10.1016/j.jcf.2016.02.006. Epub 2016 Feb 28.


Detection of Mycobacterium abscessus from deep pharyngeal swabs in cystic fibrosis.

Esther CR Jr, Kerr A, Gilligan PH.

Infect Control Hosp Epidemiol. 2015 May;36(5):618-9. doi: 10.1017/ice.2015.40. Epub 2015 Mar 2. No abstract available.


Metabolomic Evaluation of Neutrophilic Airway Inflammation in Cystic Fibrosis.

Esther CR Jr, Coakley RD, Henderson AG, Zhou YH, Wright FA, Boucher RC.

Chest. 2015 Aug;148(2):507-515. doi: 10.1378/chest.14-1800.


Potentiator ivacaftor abrogates pharmacological correction of ΔF508 CFTR in cystic fibrosis.

Cholon DM, Quinney NL, Fulcher ML, Esther CR Jr, Das J, Dokholyan NV, Randell SH, Boucher RC, Gentzsch M.

Sci Transl Med. 2014 Jul 23;6(246):246ra96. doi: 10.1126/scitranslmed.3008680.


Respiratory viruses are associated with common respiratory pathogens in cystic fibrosis.

Esther CR Jr, Lin FC, Kerr A, Miller MB, Gilligan PH.

Pediatr Pulmonol. 2014 Sep;49(9):926-31. doi: 10.1002/ppul.22917. Epub 2013 Oct 25.


Airway drug pharmacokinetics via analysis of exhaled breath condensate.

Esther CR Jr, Boucher RC, Johnson MR, Ansede JH, Donn KH, O'Riordan TG, Ghio AJ, Hirsh AJ.

Pulm Pharmacol Ther. 2014 Feb;27(1):76-82. doi: 10.1016/j.pupt.2013.07.009. Epub 2013 Aug 7.


Novel end points for clinical trials in young children with cystic fibrosis.

Simpson SJ, Mott LS, Esther CR Jr, Stick SM, Hall GL.

Expert Rev Respir Med. 2013 Jun;7(3):231-43. doi: 10.1586/ers.13.25. Review.


Lung transplant outcomes in cystic fibrosis patients with pre-operative Mycobacterium abscessus respiratory infections.

Lobo LJ, Chang LC, Esther CR Jr, Gilligan PH, Tulu Z, Noone PG.

Clin Transplant. 2013 Jul-Aug;27(4):523-9. doi: 10.1111/ctr.12140. Epub 2013 May 26.


Exhaled breath condensate adenosine tracks lung function changes in cystic fibrosis.

Esther CR Jr, Olsen BM, Lin FC, Fine J, Boucher RC.

Am J Physiol Lung Cell Mol Physiol. 2013 Apr 1;304(7):L504-9. doi: 10.1152/ajplung.00344.2012. Epub 2013 Jan 25.


Vaccine induced Hepatitis A and B protection in children at risk for cystic fibrosis associated liver disease.

Shapiro AJ, Esther CR, Leigh MW, Dellon EP.

Vaccine. 2013 Jan 30;31(6):906-11. doi: 10.1016/j.vaccine.2012.12.004. Epub 2012 Dec 20.


Exhaled breath condensate purines correlate with lung function in infants and preschoolers.

Patel K, Davis SD, Johnson R, Esther CR Jr.

Pediatr Pulmonol. 2013 Feb;48(2):182-7. doi: 10.1002/ppul.22573. Epub 2012 May 21.


Airway purinergic responses in healthy, atopic nonasthmatic, and atopic asthmatic subjects exposed to ozone.

Esther CR Jr, Peden DB, Alexis NE, Hernandez ML.

Inhal Toxicol. 2011 May;23(6):324-30. doi: 10.3109/08958378.2011.572096.


Regulation of airway nucleotides in chronic lung diseases.

Esther CR Jr, Alexis NE, Picher M.

Subcell Biochem. 2011;55:75-93. doi: 10.1007/978-94-007-1217-1_4. Review.


Nucleotide release by airway epithelia.

Lazarowski ER, Sesma JI, Seminario L, Esther CR Jr, Kreda SM.

Subcell Biochem. 2011;55:1-15. doi: 10.1007/978-94-007-1217-1_1. Review.


Elevated airway purines in COPD.

Esther CR Jr, Lazaar AL, Bordonali E, Qaqish B, Boucher RC.

Chest. 2011 Oct;140(4):954-960. doi: 10.1378/chest.10-2471. Epub 2011 Mar 31.


Impact of an evidence-based algorithm on quality of care in pediatric parapneumonic effusion and empyema.

Shomaker KL, Weiner T, Esther CR Jr.

Pediatr Pulmonol. 2011 Jul;46(7):722-8. doi: 10.1002/ppul.21429. Epub 2011 Feb 15.


Detection of rapidly growing mycobacteria in routine cultures of samples from patients with cystic fibrosis.

Esther CR Jr, Hoberman S, Fine J, Allen S, Culbreath K, Rodino K, Kerr A, Gilligan P.

J Clin Microbiol. 2011 Apr;49(4):1421-5. doi: 10.1128/JCM.02379-10. Epub 2011 Feb 2.


Atopic asthmatic subjects but not atopic subjects without asthma have enhanced inflammatory response to ozone.

Hernandez ML, Lay JC, Harris B, Esther CR Jr, Brickey WJ, Bromberg PA, Diaz-Sanchez D, Devlin RB, Kleeberger SR, Alexis NE, Peden DB.

J Allergy Clin Immunol. 2010 Sep;126(3):537-44.e1. doi: 10.1016/j.jaci.2010.06.043.


Chronic Mycobacterium abscessus infection and lung function decline in cystic fibrosis.

Esther CR Jr, Esserman DA, Gilligan P, Kerr A, Noone PG.

J Cyst Fibros. 2010 Mar;9(2):117-23. doi: 10.1016/j.jcf.2009.12.001. Epub 2010 Jan 13.


Neutrophilic inflammation is associated with altered airway hydration in stable asthmatics.

Loughlin CE, Esther CR Jr, Lazarowski ER, Alexis NE, Peden DB.

Respir Med. 2010 Jan;104(1):29-33. doi: 10.1016/j.rmed.2009.07.002. Epub 2009 Jul 30.


Mass spectrometric analysis of biomarkers and dilution markers in exhaled breath condensate reveals elevated purines in asthma and cystic fibrosis.

Esther CR Jr, Boysen G, Olsen BM, Collins LB, Ghio AJ, Swenberg JW, Boucher RC.

Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L987-93. doi: 10.1152/ajplung.90512.2008. Epub 2009 Mar 20.


Metabolomic analysis of bronchoalveolar lavage fluid from cystic fibrosis patients.

Wolak JE, Esther CR Jr, O'Connell TM.

Biomarkers. 2009 Feb;14(1):55-60. doi: 10.1080/13547500802688194.

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