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Items: 1 to 50 of 119

1.

Low dose ionizing radiation strongly stimulates insertional mutagenesis in a γH2AX dependent manner.

Zelensky AN, Schoonakker M, Brandsma I, Tijsterman M, van Gent DC, Essers J, Kanaar R.

PLoS Genet. 2020 Jan 16;16(1):e1008550. doi: 10.1371/journal.pgen.1008550. eCollection 2020 Jan.

2.

Uptake and subcellular distribution of radiolabeled polymersomes for radiotherapy.

Roobol SJ, Hartjes TA, Slotman JA, de Kruijff RM, Torrelo G, Abraham TE, Bruchertseifer F, Morgenstern A, Kanaar R, van Gent DC, Houtsmuller AB, Denkova AG, van Royen ME, Essers J.

Nanotheranostics. 2020 Jan 1;4(1):14-25. doi: 10.7150/ntno.37080. eCollection 2020.

3.

Monitoring daily physical activity of upper extremity in young and adolescent boys with Duchenne muscular dystrophy: A pilot study.

van der Geest A, Essers JMN, Bergsma A, Jansen M, de Groot IJM.

Muscle Nerve. 2019 Nov 19. doi: 10.1002/mus.26763. [Epub ahead of print]

PMID:
31742708
4.

Association of Umbilical Cord Milking vs Delayed Umbilical Cord Clamping With Death or Severe Intraventricular Hemorrhage Among Preterm Infants.

Katheria A, Reister F, Essers J, Mendler M, Hummler H, Subramaniam A, Carlo W, Tita A, Truong G, Davis-Nelson S, Schmölzer G, Chari R, Kaempf J, Tomlinson M, Yanowitz T, Beck S, Simhan H, Dempsey E, O'Donoghue K, Bhat S, Hoffman M, Faksh A, Arnell K, Rich W, Finer N, Vaucher Y, Khanna P, Meyers M, Varner M, Allman P, Szychowski J, Cutter G.

JAMA. 2019 Nov 19;322(19):1877-1886. doi: 10.1001/jama.2019.16004.

PMID:
31742630
5.

Inflammation and TGF-β Signaling Differ between Abdominal Aneurysms and Occlusive Disease.

IJpma A, Te Riet L, van de Luijtgaarden KM, van Heijningen PM, Burger J, Majoor-Krakauer D, Rouwet EV, Essers J, Verhagen HJM, van der Pluijm I.

J Cardiovasc Dev Dis. 2019 Nov 1;6(4). pii: E38. doi: 10.3390/jcdd6040038.

6.

Large Field Alpha Irradiation Setup for Radiobiological Experiments.

Roobol SJ, Kouwenberg JJM, Denkova AG, Kanaar R, Essers J.

Methods Protoc. 2019 Aug 28;2(3). pii: E75. doi: 10.3390/mps2030075.

7.

Superficial Shoulder Muscle Synergy Analysis in Facioscapulohumeral Dystrophy During Humeral Elevation Tasks.

Essers JMN, Peters A, Meijer K, Peters K, Murgia A.

IEEE Trans Neural Syst Rehabil Eng. 2019 Aug;27(8):1556-1565. doi: 10.1109/TNSRE.2019.2927765. Epub 2019 Jul 10.

PMID:
31295115
8.

HSF2BP Interacts with a Conserved Domain of BRCA2 and Is Required for Mouse Spermatogenesis.

Brandsma I, Sato K, van Rossum-Fikkert SE, van Vliet N, Sleddens E, Reuter M, Odijk H, van den Tempel N, Dekkers DHW, Bezstarosti K, Demmers JAA, Maas A, Lebbink J, Wyman C, Essers J, van Gent DC, Baarends WM, Knipscheer P, Kanaar R, Zelensky AN.

Cell Rep. 2019 Jun 25;27(13):3790-3798.e7. doi: 10.1016/j.celrep.2019.05.096.

9.

Elucidating the Influence of Tumor Presence on the Polymersome Circulation Time in Mice.

de Kruijff RM, Raavé R, Kip A, Molkenboer-Kuenen J, Roobol SJ, Essers J, Heskamp S, Denkova AG.

Pharmaceutics. 2019 May 20;11(5). pii: E241. doi: 10.3390/pharmaceutics11050241.

10.

Compression of morbidity in a progeroid mouse model through the attenuation of myostatin/activin signalling.

Alyodawi K, Vermeij WP, Omairi S, Kretz O, Hopkinson M, Solagna F, Joch B, Brandt RMC, Barnhoorn S, van Vliet N, Ridwan Y, Essers J, Mitchell R, Morash T, Pasternack A, Ritvos O, Matsakas A, Collins-Hooper H, Huber TB, Hoeijmakers JHJ, Patel K.

J Cachexia Sarcopenia Muscle. 2019 Jun;10(3):662-686. doi: 10.1002/jcsm.12404. Epub 2019 Mar 27.

11.

Fibulin-4 deficiency differentially affects cytoskeleton structure and dynamics as well as TGFβ signaling.

Burger J, van Vliet N, van Heijningen P, Kumra H, Kremers GJ, Alves M, van Cappellen G, Yanagisawa H, Reinhardt DP, Kanaar R, van der Pluijm I, Essers J.

Cell Signal. 2019 Jun;58:65-78. doi: 10.1016/j.cellsig.2019.02.008. Epub 2019 Mar 4. Review.

PMID:
30844428
12.

Dynamic heterogeneity in complex interfaces of soft interface-dominated materials.

Sagis LMC, Liu B, Li Y, Essers J, Yang J, Moghimikheirabadi A, Hinderink E, Berton-Carabin C, Schroen K.

Sci Rep. 2019 Feb 27;9(1):2938. doi: 10.1038/s41598-019-39761-7.

13.

Gestational jet lag predisposes to later-life skeletal and cardiac disease.

Chaves I, van der Eerden B, Boers R, Boers J, Streng AA, Ridwan Y, Schreuders-Koedam M, Vermeulen M, van der Pluijm I, Essers J, Gribnau J, Reiss IKM, van der Horst GTJ.

Chronobiol Int. 2019 May;36(5):657-671. doi: 10.1080/07420528.2019.1579734. Epub 2019 Feb 22.

PMID:
30793958
14.

Current and Emerging Preclinical Approaches for Imaging-Based Characterization of Atherosclerosis.

Vigne J, Thackeray J, Essers J, Makowski M, Varasteh Z, Curaj A, Karlas A, Canet-Soulas E, Mulder W, Kiessling F, Schäfers M, Botnar R, Wildgruber M, Hyafil F; Cardiovascular study group of the European Society of Molecular Imaging.

Mol Imaging Biol. 2018 Dec;20(6):869-887. doi: 10.1007/s11307-018-1264-1. Review.

PMID:
30250990
15.

Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation.

van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane EG, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz HC, Kanaar R, Essers J.

Cardiovasc Res. 2018 Nov 1;114(13):1776-1793. doi: 10.1093/cvr/cvy150.

16.

A Multimodal Imaging Approach Based on Micro-CT and Fluorescence Molecular Tomography for Longitudinal Assessment of Bleomycin-Induced Lung Fibrosis in Mice.

Ruscitti F, Ravanetti F, Donofrio G, Ridwan Y, van Heijningen P, Essers J, Villetti G, Cacchioli A, Vos W, Stellari FF.

J Vis Exp. 2018 Apr 13;(134). doi: 10.3791/56443.

PMID:
29708527
17.

[EXIT - A Possible Intervention for New- and Earlyborn Babies with Severe Hydrops Fetalis and Hydrothoraces on Both Sides].

Koch S, Essers J, Beringer O, Reister F, Hummler H, Moewes A.

Z Geburtshilfe Neonatol. 2017 Dec;221(6):286-290. doi: 10.1055/s-0043-117419. Epub 2017 Sep 15. German.

PMID:
28915526
18.

An MR-compatible antenna and application in a murine superficial hyperthermia applicator.

Raaijmakers EAL, Mestrom RMC, Sumser K, Salim G, van Rhoon GC, Essers J, Paulides MM.

Int J Hyperthermia. 2018 Sep;34(6):697-703. doi: 10.1080/02656736.2017.1369172. Epub 2017 Sep 13.

PMID:
28828891
19.

Aortic microcalcification is associated with elastin fragmentation in Marfan syndrome.

Wanga S, Hibender S, Ridwan Y, van Roomen C, Vos M, van der Made I, van Vliet N, Franken R, van Riel LA, Groenink M, Zwinderman AH, Mulder BJ, de Vries CJ, Essers J, de Waard V.

J Pathol. 2017 Nov;243(3):294-306. doi: 10.1002/path.4949. Epub 2017 Sep 21.

PMID:
28727149
20.

Dietary restriction but not angiotensin II type 1 receptor blockade improves DNA damage-related vasodilator dysfunction in rapidly aging Ercc1Δ/- mice.

Wu H, van Thiel BS, Bautista-Niño PK, Reiling E, Durik M, Leijten FPJ, Ridwan Y, Brandt RMC, van Steeg H, Dollé MET, Vermeij WP, Hoeijmakers JHJ, Essers J, van der Pluijm I, Danser AHJ, Roks AJM.

Clin Sci (Lond). 2017 Jul 13;131(15):1941-1953. doi: 10.1042/CS20170026. Print 2017 Aug 1.

PMID:
28620011
21.

Changes in physical activity and sedentary behaviour following pulmonary rehabilitation in patients with COPD.

Mesquita R, Meijer K, Pitta F, Azcuna H, Goërtz YMJ, Essers JMN, Wouters EFM, Spruit MA.

Respir Med. 2017 May;126:122-129. doi: 10.1016/j.rmed.2017.03.029. Epub 2017 Mar 31.

22.

Longitudinal assessment of bleomycin-induced lung fibrosis by Micro-CT correlates with histological evaluation in mice.

Ruscitti F, Ravanetti F, Essers J, Ridwan Y, Belenkov S, Vos W, Ferreira F, KleinJan A, van Heijningen P, Van Holsbeke C, Cacchioli A, Villetti G, Stellari FF.

Multidiscip Respir Med. 2017 Apr 10;12:8. doi: 10.1186/s40248-017-0089-0. eCollection 2017.

23.

Brain Renin-Angiotensin System: Does It Exist?

van Thiel BS, Góes Martini A, Te Riet L, Severs D, Uijl E, Garrelds IM, Leijten FPJ, van der Pluijm I, Essers J, Qadri F, Alenina N, Bader M, Paulis L, Rajkovicova R, Domenig O, Poglitsch M, Danser AHJ.

Hypertension. 2017 Jun;69(6):1136-1144. doi: 10.1161/HYPERTENSIONAHA.116.08922. Epub 2017 Apr 10.

PMID:
28396529
24.

Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.

Baar MP, Brandt RMC, Putavet DA, Klein JDD, Derks KWJ, Bourgeois BRM, Stryeck S, Rijksen Y, van Willigenburg H, Feijtel DA, van der Pluijm I, Essers J, van Cappellen WA, van IJcken WF, Houtsmuller AB, Pothof J, de Bruin RWF, Madl T, Hoeijmakers JHJ, Campisi J, de Keizer PLJ.

Cell. 2017 Mar 23;169(1):132-147.e16. doi: 10.1016/j.cell.2017.02.031.

25.

Activity Levels and Exercise Motivation in Patients With COPD and Their Resident Loved Ones.

Mesquita R, Nakken N, Janssen DJA, van den Bogaart EHA, Delbressine JML, Essers JMN, Meijer K, van Vliet M, de Vries GJ, Muris JWM, Pitta F, Wouters EFM, Spruit MA.

Chest. 2017 May;151(5):1028-1038. doi: 10.1016/j.chest.2016.12.021. Epub 2017 Jan 10.

PMID:
28087303
26.

Defective Connective Tissue Remodeling in Smad3 Mice Leads to Accelerated Aneurysmal Growth Through Disturbed Downstream TGF-β Signaling.

van der Pluijm I, van Vliet N, von der Thusen JH, Robertus JL, Ridwan Y, van Heijningen PM, van Thiel BS, Vermeij M, Hoeks SE, Buijs-Offerman RMGB, Verhagen HJM, Kanaar R, Bertoli-Avella AM, Essers J.

EBioMedicine. 2016 Oct;12:280-294. doi: 10.1016/j.ebiom.2016.09.006. Epub 2016 Sep 10.

27.

Function of Ltbp-4L and fibulin-4 in survival and elastogenesis in mice.

Bultmann-Mellin I, Essers J, van Heijingen PM, von Melchner H, Sengle G, Sterner-Kock A.

Dis Model Mech. 2016 Nov 1;9(11):1367-1374. Epub 2016 Sep 1.

28.

Reply.

Te Riet L, Danser AH, Essers J.

J Hypertens. 2016 Aug;34(8):1654-5. doi: 10.1097/HJH.0000000000000982. No abstract available.

PMID:
27356003
29.

Commentary: Older adults can improve compensatory stepping with repeated postural perturbations.

McCrum C, Essers JM, Jie LJ, Liu WY, Meijer K.

Front Aging Neurosci. 2016 May 10;8:111. doi: 10.3389/fnagi.2016.00111. eCollection 2016. No abstract available.

30.

Evaluation of a Fluorescent and Radiolabeled Hybrid Somatostatin Analog In Vitro and in Mice Bearing H69 Neuroendocrine Xenografts.

Santini C, Kuil J, Bunschoten A, Pool S, de Blois E, Ridwan Y, Essers J, Bernsen MR, van Leeuwen FW, de Jong M.

J Nucl Med. 2016 Aug;57(8):1289-95. doi: 10.2967/jnumed.115.164970. Epub 2016 Apr 28.

31.

In Vivo Quantitative Assessment of Myocardial Structure, Function, Perfusion and Viability Using Cardiac Micro-computed Tomography.

van Deel E, Ridwan Y, van Vliet JN, Belenkov S, Essers J.

J Vis Exp. 2016 Feb 16;(108):53603. doi: 10.3791/53603.

32.

AT1-receptor blockade, but not renin inhibition, reduces aneurysm growth and cardiac failure in fibulin-4 mice.

Te Riet L, van Deel ED, van Thiel BS, Moltzer E, van Vliet N, Ridwan Y, van Veghel R, van Heijningen PM, Robertus JL, Garrelds IM, Vermeij M, van der Pluijm I, Danser AH, Essers J.

J Hypertens. 2016 Apr;34(4):654-65. doi: 10.1097/HJH.0000000000000845.

PMID:
26828783
33.

Fibulin-4 deficiency increases TGF-β signalling in aortic smooth muscle cells due to elevated TGF-β2 levels.

Ramnath NW, Hawinkels LJ, van Heijningen PM, te Riet L, Paauwe M, Vermeij M, Danser AH, Kanaar R, ten Dijke P, Essers J.

Sci Rep. 2015 Nov 26;5:16872. doi: 10.1038/srep16872.

34.

Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping.

Cutler DJ, Zwick ME, Okou DT, Prahalad S, Walters T, Guthery SL, Dubinsky M, Baldassano R, Crandall WV, Rosh J, Markowitz J, Stephens M, Kellermayer R, Pfefferkorn M, Heyman MB, LeLeiko N, Mack D, Moulton D, Kappelman MD, Kumar A, Prince J, Bose P, Mondal K, Ramachandran D, Bohnsack JF, Griffiths AM, Haberman Y, Essers J, Thompson SD, Aronow B, Keljo DJ, Hyams JS, Denson LA; PRO-KIIDS Research Group, Kugathasan S.

PLoS One. 2015 Jun 22;10(6):e0128074. doi: 10.1371/journal.pone.0128074. eCollection 2015.

35.

The renin-angiotensin system and its involvement in vascular disease.

van Thiel BS, van der Pluijm I, te Riet L, Essers J, Danser AH.

Eur J Pharmacol. 2015 Sep 15;763(Pt A):3-14. doi: 10.1016/j.ejphar.2015.03.090. Epub 2015 May 16. Review.

PMID:
25987425
36.

Risk Indicators for Air Leaks in Preterm Infants Exposed to Restrictive Use of Endotracheal Intubation.

Hummler HD, Parys E, Mayer B, Essers J, Fuchs H, Schmid M.

Neonatology. 2015;108(1):1-7. doi: 10.1159/000375361. Epub 2015 Mar 21.

PMID:
25825229
37.

BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells.

Reuter M, Zelensky A, Smal I, Meijering E, van Cappellen WA, de Gruiter HM, van Belle GJ, van Royen ME, Houtsmuller AB, Essers J, Kanaar R, Wyman C.

J Cell Biol. 2015 Mar 16;208(6):857. doi: 10.1083/jcb.20140501402182015c. No abstract available.

38.

Optical Imaging of Tumor Response to Hyperbaric Oxygen Treatment and Irradiation in an Orthotopic Mouse Model of Head and Neck Squamous Cell Carcinoma.

Braks JA, Spiegelberg L, Koljenovic S, Ridwan Y, Keereweer S, Kanaar R, Wolvius EB, Essers J.

Mol Imaging Biol. 2015 Oct;17(5):633-42. doi: 10.1007/s11307-015-0834-8.

39.

BRCA2 diffuses as oligomeric clusters with RAD51 and changes mobility after DNA damage in live cells.

Reuter M, Zelensky A, Smal I, Meijering E, van Cappellen WA, de Gruiter HM, van Belle GJ, van Royen ME, Houtsmuller AB, Essers J, Kanaar R, Wyman C.

J Cell Biol. 2014 Dec 8;207(5):599-613. doi: 10.1083/jcb.201405014. Erratum in: J Cell Biol. 2015 Mar 16;208(6):857.

40.

A mRad51-GFP antimorphic allele affects homologous recombination and DNA damage sensitivity.

Uringa EJ, Baldeyron C, Odijk H, Wassenaar E, van Cappellen WA, Maas A, Hoeijmakers JH, Baarends WM, Kanaar R, Essers J.

DNA Repair (Amst). 2015 Jan;25:27-40. doi: 10.1016/j.dnarep.2014.11.002. Epub 2014 Nov 18.

PMID:
25463395
41.

Extracellular matrix defects in aneurysmal Fibulin-4 mice predispose to lung emphysema.

Ramnath NW, van de Luijtgaarden KM, van der Pluijm I, van Nimwegen M, van Heijningen PM, Swagemakers SM, van Thiel BS, Ridwan RY, van Vliet N, Vermeij M, Hawinkels LJ, de Munck A, Dzyubachyk O, Meijering E, van der Spek P, Rottier R, Yanagisawa H, Hendriks RW, Kanaar R, Rouwet EV, Kleinjan A, Essers J.

PLoS One. 2014 Sep 25;9(9):e106054. doi: 10.1371/journal.pone.0106054. eCollection 2014.

42.

Imaging preclinical tumour models: improving translational power.

de Jong M, Essers J, van Weerden WM.

Nat Rev Cancer. 2014 Jul;14(7):481-93. doi: 10.1038/nrc3751. Epub 2014 Jun 19. Review.

PMID:
24943811
43.

Gene expression analysis reveals inhibition of radiation-induced TGFβ-signaling by hyperbaric oxygen therapy in mouse salivary glands.

Spiegelberg L, Swagemakers SM, Van Ijcken WF, Oole E, Wolvius EB, Essers J, Braks JA.

Mol Med. 2014 Jul 10;20:257-69. doi: 10.2119/molmed.2014.00003.

44.

Absence of cardiovascular manifestations in a haploinsufficient Tgfbr1 mouse model.

Renard M, Trachet B, Casteleyn C, Campens L, Cornillie P, Callewaert B, Deleye S, Vandeghinste B, van Heijningen PM, Dietz H, De Vos F, Essers J, Staelens S, Segers P, Loeys B, Coucke P, De Paepe A, De Backer J.

PLoS One. 2014 Feb 24;9(2):e89749. doi: 10.1371/journal.pone.0089749. eCollection 2014.

45.

An inverse dynamic analysis on the influence of upper limb gravity compensation during reaching.

Essers JM, Meijer K, Murgia A, Bergsma A, Verstegen P.

IEEE Int Conf Rehabil Robot. 2013 Jun;2013:6650368. doi: 10.1109/ICORR.2013.6650368.

PMID:
24187187
46.

Increased effectiveness of early therapy with anti-tumor necrosis factor-α vs an immunomodulator in children with Crohn's disease.

Walters TD, Kim MO, Denson LA, Griffiths AM, Dubinsky M, Markowitz J, Baldassano R, Crandall W, Rosh J, Pfefferkorn M, Otley A, Heyman MB, LeLeiko N, Baker S, Guthery SL, Evans J, Ziring D, Kellermayer R, Stephens M, Mack D, Oliva-Hemker M, Patel AS, Kirschner B, Moulton D, Cohen S, Kim S, Liu C, Essers J, Kugathasan S, Hyams JS; PRO-KIIDS Research Group.

Gastroenterology. 2014 Feb;146(2):383-91. doi: 10.1053/j.gastro.2013.10.027. Epub 2013 Oct 23.

PMID:
24162032
47.

Report of the CCFA pediatric bone, growth and muscle health workshop, New York City, November 11-12, 2011, with updates.

Sylvester FA, Gordon CM, Thayu M, Burnham JM, Denson LA, Essers J, Ferrari S, Gupta N, Hewison M, Koletzko S, McCabe L, Pappa H, Sanderson I, Ward L, Zanotti S.

Inflamm Bowel Dis. 2013 Dec;19(13):2919-26. doi: 10.1097/MIB.0b013e3182a5a004.

PMID:
23974992
48.

Rad54 is required for the normal development of male and female germ cells and contributes to the maintainance of their genome integrity after genotoxic stress.

Messiaen S, Le Bras A, Duquenne C, Barroca V, Moison D, Déchamps N, Doussau M, Bauchet AL, Guerquin MJ, Livera G, Essers J, Kanaar R, Habert R, Bernardino-Sgherri J.

Cell Death Dis. 2013 Aug 15;4:e774. doi: 10.1038/cddis.2013.281.

49.

Caffeine suppresses homologous recombination through interference with RAD51-mediated joint molecule formation.

Zelensky AN, Sanchez H, Ristic D, Vidic I, van Rossum-Fikkert SE, Essers J, Wyman C, Kanaar R.

Nucleic Acids Res. 2013 Jul;41(13):6475-89. doi: 10.1093/nar/gkt375. Epub 2013 May 10.

50.

Disruption of TTDA results in complete nucleotide excision repair deficiency and embryonic lethality.

Theil AF, Nonnekens J, Steurer B, Mari PO, de Wit J, Lemaitre C, Marteijn JA, Raams A, Maas A, Vermeij M, Essers J, Hoeijmakers JH, Giglia-Mari G, Vermeulen W.

PLoS Genet. 2013 Apr;9(4):e1003431. doi: 10.1371/journal.pgen.1003431. Epub 2013 Apr 18.

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