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Items: 29

1.

Expression of the mRNA encoding truncated PPAR alpha does not correlate with hepatic insensitivity to peroxisome proliferators.

Hanselman JC, Vartanian MA, Koester BP, Gray SA, Essenburg AD, Rea TJ, Bisgaier CL, Pape ME.

Mol Cell Biochem. 2001 Jan;217(1-2):91-7.

PMID:
11269670
2.

Elevated low-density lipoprotein in Alzheimer's disease correlates with brain abeta 1-42 levels.

Kuo YM, Emmerling MR, Bisgaier CL, Essenburg AD, Lampert HC, Drumm D, Roher AE.

Biochem Biophys Res Commun. 1998 Nov 27;252(3):711-5.

PMID:
9837771
3.

A novel compound that elevates high density lipoprotein and activates the peroxisome proliferator activated receptor.

Bisgaier CL, Essenburg AD, Barnett BC, Auerbach BJ, Haubenwallner S, Leff T, White AD, Creger P, Pape ME, Rea TJ, Newton RS.

J Lipid Res. 1998 Jan;39(1):17-30. Erratum in: J Lipid Res 1998 Jun;39(6):1317.

4.

Attenuation of plasma low density lipoprotein cholesterol by select 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors in mice devoid of low density lipoprotein receptors.

Bisgaier CL, Essenburg AD, Auerbach BJ, Pape ME, Sekerke CS, Gee A, Wölle S, Newton RS.

J Lipid Res. 1997 Dec;38(12):2502-15.

5.

Large versus small unilamellar vesicles mediate reverse cholesterol transport in vivo into two distinct hepatic metabolic pools. Implications for the treatment of atherosclerosis.

Rodrigueza WV, Mazany KD, Essenburg AD, Pape ME, Rea TJ, Bisgaier CL, Williams KJ.

Arterioscler Thromb Vasc Biol. 1997 Oct;17(10):2132-9.

PMID:
9351382
6.

Decreased HDL cholesterol levels but normal lipid absorption, growth, and feeding behavior in apolipoprotein A-IV knockout mice.

Weinstock PH, Bisgaier CL, Hayek T, Aalto-Setala K, Sehayek E, Wu L, Sheiffele P, Merkel M, Essenburg AD, Breslow JL.

J Lipid Res. 1997 Sep;38(9):1782-94.

7.

Inhibitors of acyl-CoA:cholesterol acyltransferase: novel trisubstituted ureas as hypocholesterolemic agents.

Purchase TS, Essenburg AD, Hamelehle KL, Hes MS, Holmes A, Krause BR, Stanfield RL, Trivedi BK.

Bioorg Med Chem. 1997 Apr;5(4):739-47.

PMID:
9158873
8.

Opposite effects of bezafibrate and gemfibrozil in both normal and hypertriglyceridemic rats.

Krause BR, Barnett BC, Essenburg AD, Kieft KA, Auerbach BJ, Bousley R, Stanfield R, Newton RS, Bisgaier CL.

Atherosclerosis. 1996 Nov 15;127(1):91-101.

PMID:
9006809
9.

Heterocyclic ureas: inhibitors of acyl-CoA:cholesterol O-acyltransferase as hypocholesterolemic agents.

White AD, Creswell MW, Chucholowski AW, Blankley CJ, Wilson MW, Bousley RF, Essenburg AD, Hamelehle KL, Krause BR, Stanfield RL, Dominick MA, Neub M.

J Med Chem. 1996 Oct 25;39(22):4382-95.

PMID:
8893833
10.

Hypolipidemic activity of select fibrates correlates to changes in hepatic apolipoprotein C-III expression: a potential physiologic basis for their mode of action.

Haubenwallner S, Essenburg AD, Barnett BC, Pape ME, DeMattos RB, Krause BR, Minton LL, Auerbach BJ, Newton RS, Leff T, et al.

J Lipid Res. 1995 Dec;36(12):2541-51.

11.

Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes.

Weinstock PH, Bisgaier CL, Aalto-Setälä K, Radner H, Ramakrishnan R, Levak-Frank S, Essenburg AD, Zechner R, Breslow JL.

J Clin Invest. 1995 Dec;96(6):2555-68.

12.

Bioisosterism in drug design: identification of and structure-activity relationships in a series of glycine anilide ACAT inhibitors.

Roark WH, Padia J, Bolton GL, Blankley CJ, Essenburg AD, Stanfield RL, Bousley RF, Krause BR, Roth BD.

Bioorg Med Chem. 1995 Jan;3(1):29-39.

PMID:
8612044
13.

Cholesteryl ester transfer protein inhibition by PD 140195.

Bisgaier CL, Essenburg AD, Minton LL, Homan R, Blankley CJ, White A.

Lipids. 1994 Dec;29(12):811-8.

PMID:
7854005
14.

Inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). 7. Development of a series of substituted N-phenyl-N'-[(1-phenylcyclopentyl)methyl]ureas with enhanced hypocholesterolemic activity.

Trivedi BK, Purchase TS, Holmes A, Augelli-Szafran CE, Essenburg AD, Hamelehle KL, Stanfield RL, Bousley RF, Krause BR.

J Med Chem. 1994 May 27;37(11):1652-9.

PMID:
8201599
15.

Intestinal expression of human apolipoprotein A-IV in transgenic mice fails to influence dietary lipid absorption or feeding behavior.

Aalto-Setälä K, Bisgaier CL, Ho A, Kieft KA, Traber MG, Kayden HJ, Ramakrishnan R, Walsh A, Essenburg AD, Breslow JL.

J Clin Invest. 1994 Apr;93(4):1776-86.

16.

Inhibitors of acyl-Coa:cholesterol acyltransferase. 4. A novel series of urea ACAT inhibitors as potential hypocholesterolemic agents.

Trivedi BK, Holmes A, Stoeber TL, Blankley CJ, Roark WH, Picard JA, Shaw MK, Essenburg AD, Stanfield RL, Krause BR.

J Med Chem. 1993 Oct 29;36(22):3300-7.

PMID:
8230120
17.

Inhibitors of acyl-CoA:cholesterol acyltransferase. 5. Identification and structure-activity relationships of novel beta-ketoamides as hypocholesterolemic agents.

Augelli-Szafran CE, Blankley CJ, Roth BD, Trivedi BK, Bousley RF, Essenburg AD, Hamelehle KL, Krause BR, Stanfield RL.

J Med Chem. 1993 Oct 1;36(20):2943-9.

PMID:
8411011
18.

Use of fluorescent cholesteryl ester microemulsions in cholesteryl ester transfer protein assays.

Bisgaier CL, Minton LL, Essenburg AD, White A, Homan R.

J Lipid Res. 1993 Sep;34(9):1625-34.

19.

Inhibitors of acyl-CoA:cholesterol acyltransferase (ACAT). 2. Modification of fatty acid anilide ACAT inhibitors: bioisosteric replacement of the amide bond.

Roark WH, Roth BD, Holmes A, Trivedi BK, Kieft KA, Essenburg AD, Krause BR, Stanfield RL.

J Med Chem. 1993 May 28;36(11):1662-8.

PMID:
8496932
20.

Inhibitors of acyl-CoA:cholesterol acyltransferase. 1. Identification and structure-activity relationships of a novel series of fatty acid anilide hypocholesterolemic agents.

Roth BD, Blankley CJ, Hoefle ML, Holmes A, Roark WH, Trivedi BK, Essenburg AD, Kieft KA, Krause BR, Stanfield RL.

J Med Chem. 1992 May 1;35(9):1609-17.

PMID:
1578488
21.

Synthesis of novel angiotensin converting enzyme inhibitor quinapril and related compounds. A divergence of structure-activity relationships for non-sulfhydryl and sulfhydryl types.

Klutchko S, Blankley CJ, Fleming RW, Hinkley JM, Werner AE, Nordin I, Holmes A, Hoefle ML, Cohen DM, Essenburg AD, et al.

J Med Chem. 1986 Oct;29(10):1953-61.

PMID:
3020249
22.

Synthesis and biological activity of modified peptide inhibitors of angiotensin-converting enzyme.

Roark WH, Tinney FJ, Cohen D, Essenburg AD, Kaplan HR.

J Med Chem. 1985 Sep;28(9):1291-5.

PMID:
2993618
23.

CI-906 and CI-907: new orally active nonsulfhydryl angiotensin-converting enzyme inhibitors.

Kaplan HR, Cohen DM, Essenburg AD, Major TC, Mertz TE, Ryan MJ.

Fed Proc. 1984 Apr;43(5):1326-9.

PMID:
6323223
24.

Antihypertensive effects of CI-907 (indolapril): a novel nonsulfhydryl angiotensin converting enzyme inhibitor.

Ryan MJ, Boucher DM, Cohen DM, Essenburg AD, Major TC, Mertz TE, Olszewski BJ, Randolph AE, Singer RM, Kaplan HR.

J Pharmacol Exp Ther. 1984 Feb;228(2):312-8.

PMID:
6319675
25.

Derivatives of the potent angiotensin converting enzyme inhibitor 5(S)-benzamido-4-oxo-6-phenylhexanoyl-L-proline: effect of changes at positions 2 and 5 of the hexanoic acid portion.

Almquist RG, Crase J, Jennings-White C, Meyer RF, Hoefle ML, Smith RD, Essenburg AD, Kaplan HR.

J Med Chem. 1982 Nov;25(11):1292-9.

PMID:
6292422
26.

Angiotensin converting enzyme inhibitors: modifications of a tripeptide analogue.

Meyer RF, Essenburg AD, Smith RD, Kaplan HR.

J Med Chem. 1982 Aug;25(8):996-9.

PMID:
6288947
27.

Novel synthesis of (S)-1-[5-(benzoylamino)-1,4-dioxo-6-phenylhexyl]-L-proline and analogues: potent angiotensin converting enzyme inhibitors.

Meyer RF, Nicolaides ED, Tinney FJ, Lunney EA, Holmes A, Hoefle ML, Smith RD, Essenburg AD, Kaplan HR, Almquist RG.

J Med Chem. 1981 Aug;24(8):964-9.

PMID:
6173481
28.

Synthesis and angiotensin-converting enzyme inhibitory activity of 3-(Mercaptomethyl)-2-oxo-1-pyrrolidineacetic acids and 3-(Mercaptomethyl)-2-oxo-1-piperidineacetic acids.

Klutchko S, Hoefle ML, Smith RD, Essenburg AD, Parker RB, Nemeth VL, Ryan MJ, Dugan DH, Kaplan HR.

J Med Chem. 1981 Jan;24(1):104-9.

PMID:
6259352
29.

Pharmacologic evaluation of CI-775, a cardioselective beta adrenergic antagonist.

Hastings SG, Smith RD, Corey RM, Essenburg AD, Pettway CE, Tessman DK.

Arch Int Pharmacodyn Ther. 1977 Mar;226(1):81-99. No abstract available.

PMID:
17372

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