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Items: 49

1.

Short-term safety of mTOR inhibitors in infants and very young children with tuberous sclerosis complex (TSC): Multicentre clinical experience.

Krueger DA, Capal JK, Curatolo P, Devinsky O, Ess K, Tzadok M, Koenig MK, Narayanan V, Ramos F, Jozwiak S, de Vries P, Jansen AC, Wong M, Mowat D, Lawson J, Bruns S, Franz DN; TSCure Research Group.

Eur J Paediatr Neurol. 2018 Nov;22(6):1066-1073. doi: 10.1016/j.ejpn.2018.06.007. Epub 2018 Jul 4.

PMID:
30005812
2.

Direct evidence of impaired neuronal Na/K-ATPase pump function in alternating hemiplegia of childhood.

Simmons CQ, Thompson CH, Cawthon BE, Westlake G, Swoboda KJ, Kiskinis E, Ess KC, George AL Jr.

Neurobiol Dis. 2018 Jul;115:29-38. doi: 10.1016/j.nbd.2018.03.009. Epub 2018 Mar 19.

PMID:
29567111
3.

Reproducible and efficient generation of functionally active neurons from human hiPSCs for preclinical disease modeling.

Xie Y, Schutte RJ, Ng NN, Ess KC, Schwartz PH, O'Dowd DK.

Stem Cell Res. 2018 Jan;26:84-94. doi: 10.1016/j.scr.2017.12.003. Epub 2017 Dec 9.

4.

Loss of mTORC2 signaling in oligodendrocyte precursor cells delays myelination.

Grier MD, West KL, Kelm ND, Fu C, Does MD, Parker B, McBrier E, Lagrange AH, Ess KC, Carson RP.

PLoS One. 2017 Nov 21;12(11):e0188417. doi: 10.1371/journal.pone.0188417. eCollection 2017.

5.

Heterozygous loss of TSC2 alters p53 signaling and human stem cell reprogramming.

Armstrong LC, Westlake G, Snow JP, Cawthon B, Armour E, Bowman AB, Ess KC.

Hum Mol Genet. 2017 Dec 1;26(23):4629-4641. doi: 10.1093/hmg/ddx345.

6.

Research conference summary from the 2014 International Task Force on ATP1A3-Related Disorders.

Rosewich H, Sweney MT, DeBrosse S, Ess K, Ozelius L, Andermann E, Andermann F, Andrasco G, Belgrade A, Brashear A, Ciccodicola S, Egan L, George AL Jr, Lewelt A, Magelby J, Merida M, Newcomb T, Platt V, Poncelin D, Reyna S, Sasaki M, Sotero de Menezes M, Sweadner K, Viollet L, Zupanc M, Silver K, Swoboda K.

Neurol Genet. 2017 Mar 2;3(2):e139. doi: 10.1212/NXG.0000000000000139. eCollection 2017 Apr.

7.

Primary Intraventricular Hemorrhage: Clinical Characteristics and Outcomes.

Weinstein R, Ess K, Sirdar B, Song S, Cutting S.

J Stroke Cerebrovasc Dis. 2017 May;26(5):995-999. doi: 10.1016/j.jstrokecerebrovasdis.2016.11.114. Epub 2017 Jan 19.

PMID:
28111008
8.

Myelin volume fraction imaging with MRI.

West KL, Kelm ND, Carson RP, Gochberg DF, Ess KC, Does MD.

Neuroimage. 2018 Nov 15;182:511-521. doi: 10.1016/j.neuroimage.2016.12.067. Epub 2016 Dec 23.

PMID:
28025129
9.

Advances and Future Directions for Tuberous Sclerosis Complex Research: Recommendations From the 2015 Strategic Planning Conference.

Sahin M, Henske EP, Manning BD, Ess KC, Bissler JJ, Klann E, Kwiatkowski DJ, Roberds SL, Silva AJ, Hillaire-Clarke CS, Young LR, Zervas M, Mamounas LA; Tuberous Sclerosis Complex Working Group to Update the Research Plan.

Pediatr Neurol. 2016 Jul;60:1-12. doi: 10.1016/j.pediatrneurol.2016.03.015. Epub 2016 Apr 2.

10.

Genomic Instability Associated with p53 Knockdown in the Generation of Huntington's Disease Human Induced Pluripotent Stem Cells.

Tidball AM, Neely MD, Chamberlin R, Aboud AA, Kumar KK, Han B, Bryan MR, Aschner M, Ess KC, Bowman AB.

PLoS One. 2016 Mar 16;11(3):e0150372. doi: 10.1371/journal.pone.0150372. eCollection 2016.

11.

Hypomyelination following deletion of Tsc2 in oligodendrocyte precursors.

Carson RP, Kelm ND, West KL, Does MD, Fu C, Weaver G, McBrier E, Parker B, Grier MD, Ess KC.

Ann Clin Transl Neurol. 2015 Oct 27;2(12):1041-54. doi: 10.1002/acn3.254. eCollection 2015 Dec.

12.

Dynamic tubers in tuberous sclerosis complex: A window for intervention?

Ess KC, Chugani HT.

Neurology. 2015 Nov 3;85(18):1530-1. doi: 10.1212/WNL.0000000000002056. Epub 2015 Oct 2. No abstract available.

PMID:
26432847
13.

Evaluation of diffusion kurtosis imaging in ex vivo hypomyelinated mouse brains.

Kelm ND, West KL, Carson RP, Gochberg DF, Ess KC, Does MD.

Neuroimage. 2016 Jan 1;124(Pt A):612-626. doi: 10.1016/j.neuroimage.2015.09.028. Epub 2015 Sep 21.

14.

Combinatorial polymer matrices enhance in vitro maturation of human induced pluripotent stem cell-derived cardiomyocytes.

Chun YW, Balikov DA, Feaster TK, Williams CH, Sheng CC, Lee JB, Boire TC, Neely MD, Bellan LM, Ess KC, Bowman AB, Sung HJ, Hong CC.

Biomaterials. 2015 Oct;67:52-64. doi: 10.1016/j.biomaterials.2015.07.004. Epub 2015 Jul 14.

15.

A post-developmental genetic screen for zebrafish models of inherited liver disease.

Kim SH, Wu SY, Baek JI, Choi SY, Su Y, Flynn CR, Gamse JT, Ess KC, Hardiman G, Lipschutz JH, Abumrad NN, Rockey DC.

PLoS One. 2015 May 7;10(5):e0125980. doi: 10.1371/journal.pone.0125980. eCollection 2015.

16.

Interaction with WDR5 promotes target gene recognition and tumorigenesis by MYC.

Thomas LR, Wang Q, Grieb BC, Phan J, Foshage AM, Sun Q, Olejniczak ET, Clark T, Dey S, Lorey S, Alicie B, Howard GC, Cawthon B, Ess KC, Eischen CM, Zhao Z, Fesik SW, Tansey WP.

Mol Cell. 2015 May 7;58(3):440-52. doi: 10.1016/j.molcel.2015.02.028. Epub 2015 Mar 26.

17.

Tuberous sclerosis associated neuropsychiatric disorders (TAND) and the TAND Checklist.

de Vries PJ, Whittemore VH, Leclezio L, Byars AW, Dunn D, Ess KC, Hook D, King BH, Sahin M, Jansen A.

Pediatr Neurol. 2015 Jan;52(1):25-35. doi: 10.1016/j.pediatrneurol.2014.10.004. Epub 2014 Oct 16.

18.

A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease.

Tidball AM, Bryan MR, Uhouse MA, Kumar KK, Aboud AA, Feist JE, Ess KC, Neely MD, Aschner M, Bowman AB.

Hum Mol Genet. 2015 Apr 1;24(7):1929-44. doi: 10.1093/hmg/ddu609. Epub 2014 Dec 8.

19.

PARK2 patient neuroprogenitors show increased mitochondrial sensitivity to copper.

Aboud AA, Tidball AM, Kumar KK, Neely MD, Han B, Ess KC, Hong CC, Erikson KM, Hedera P, Bowman AB.

Neurobiol Dis. 2015 Jan;73:204-12. doi: 10.1016/j.nbd.2014.10.002. Epub 2014 Oct 12.

20.

Identification of a common Wnt-associated genetic signature across multiple cell types in pulmonary arterial hypertension.

West JD, Austin ED, Gaskill C, Marriott S, Baskir R, Bilousova G, Jean JC, Hemnes AR, Menon S, Bloodworth NC, Fessel JP, Kropski JA, Irwin D, Ware LB, Wheeler L, Hong CC, Meyrick B, Loyd JE, Bowman AB, Ess KC, Klemm DJ, Young PP, Merryman WD, Kotton D, Majka SM.

Am J Physiol Cell Physiol. 2014 Sep 1;307(5):C415-30. doi: 10.1152/ajpcell.00057.2014. Epub 2014 May 28.

21.

Gammaretroviral vector encoding a fluorescent marker to facilitate detection of reprogrammed human fibroblasts during iPSC generation.

Srinivasakumar N, Zaboikin M, Tidball AM, Aboud AA, Neely MD, Ess KC, Bowman AB, Schuening FG.

PeerJ. 2013 Dec 10;1:e224. doi: 10.7717/peerj.224. eCollection 2013.

22.

Multi-organ abnormalities and mTORC1 activation in zebrafish model of multiple acyl-CoA dehydrogenase deficiency.

Kim SH, Scott SA, Bennett MJ, Carson RP, Fessel J, Brown HA, Ess KC.

PLoS Genet. 2013 Jun;9(6):e1003563. doi: 10.1371/journal.pgen.1003563. Epub 2013 Jun 13.

23.

Patient heal thyself: modeling and treating neurological disorders using patient-derived stem cells.

Ess KC.

Exp Biol Med (Maywood). 2013 Mar;238(3):308-14. doi: 10.1177/1535370213480713. Review.

24.

Heterozygous inactivation of tsc2 enhances tumorigenesis in p53 mutant zebrafish.

Kim SH, Kowalski ML, Carson RP, Bridges LR, Ess KC.

Dis Model Mech. 2013 Jul;6(4):925-33. doi: 10.1242/dmm.011494. Epub 2013 Mar 27.

25.

Autophagy induction is a Tor- and Tp53-independent cell survival response in a zebrafish model of disrupted ribosome biogenesis.

Boglev Y, Badrock AP, Trotter AJ, Du Q, Richardson EJ, Parslow AC, Markmiller SJ, Hall NE, de Jong-Curtain TA, Ng AY, Verkade H, Ober EA, Field HA, Shin D, Shin CH, Hannan KM, Hannan RD, Pearson RB, Kim SH, Ess KC, Lieschke GJ, Stainier DY, Heath JK.

PLoS Genet. 2013;9(2):e1003279. doi: 10.1371/journal.pgen.1003279. Epub 2013 Feb 7.

26.

Conditional and domain-specific inactivation of the Tsc2 gene in neural progenitor cells.

Fu C, Ess KC.

Genesis. 2013 Apr;51(4):284-92. doi: 10.1002/dvg.22377. Epub 2013 Mar 13.

27.

Genetic risk for Parkinson's disease correlates with alterations in neuronal manganese sensitivity between two human subjects.

Aboud AA, Tidball AM, Kumar KK, Neely MD, Ess KC, Erikson KM, Bowman AB.

Neurotoxicology. 2012 Dec;33(6):1443-9. doi: 10.1016/j.neuro.2012.10.009. Epub 2012 Oct 22.

28.

Deletion of Rictor in neural progenitor cells reveals contributions of mTORC2 signaling to tuberous sclerosis complex.

Carson RP, Fu C, Winzenburger P, Ess KC.

Hum Mol Genet. 2013 Jan 1;22(1):140-52. doi: 10.1093/hmg/dds414. Epub 2012 Oct 9.

29.

DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction.

Neely MD, Litt MJ, Tidball AM, Li GG, Aboud AA, Hopkins CR, Chamberlin R, Hong CC, Ess KC, Bowman AB.

ACS Chem Neurosci. 2012 Jun 20;3(6):482-91. doi: 10.1021/cn300029t. Epub 2012 Mar 5.

30.

Cystogenesis and elongated primary cilia in Tsc1-deficient distal convoluted tubules.

Armour EA, Carson RP, Ess KC.

Am J Physiol Renal Physiol. 2012 Aug 15;303(4):F584-92. doi: 10.1152/ajprenal.00141.2012. Epub 2012 Jun 6.

31.

New therapies for tuber-less sclerosis: white matter matters?

Ess KC, Roach ES.

Neurology. 2012 Feb 21;78(8):520-1. doi: 10.1212/WNL.0b013e318248a232. Epub 2012 Jan 18. No abstract available.

PMID:
22262747
32.

GABAergic interneuron development and function is modulated by the Tsc1 gene.

Fu C, Cawthon B, Clinkscales W, Bruce A, Winzenburger P, Ess KC.

Cereb Cortex. 2012 Sep;22(9):2111-9. doi: 10.1093/cercor/bhr300. Epub 2011 Oct 20.

33.

Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin.

Carson RP, Van Nielen DL, Winzenburger PA, Ess KC.

Neurobiol Dis. 2012 Jan;45(1):369-80. doi: 10.1016/j.nbd.2011.08.024. Epub 2011 Aug 26.

34.

Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin.

Kim SH, Speirs CK, Solnica-Krezel L, Ess KC.

Dis Model Mech. 2011 Mar;4(2):255-67. doi: 10.1242/dmm.005587. Epub 2010 Oct 19.

35.

Tuberous sclerosis complex: a brave new world?

Ess KC.

Curr Opin Neurol. 2010 Apr;23(2):189-93. doi: 10.1097/WCO.0b013e32832c4ff5. Review.

36.

Tuberous sclerosis complex: everything old is new again.

Ess KC.

J Neurodev Disord. 2009 Jun;1(2):141-9. doi: 10.1007/s11689-009-9014-y. Epub 2009 May 6.

37.

Treatment of infantile spasms in tuberous sclerosis complex: dismal outcomes but future hope?

Ess KC.

Nat Clin Pract Neurol. 2009 Feb;5(2):72-3. doi: 10.1038/ncpneuro0994. Epub 2008 Dec 23.

PMID:
19107107
38.

Abnormal glutamate homeostasis and impaired synaptic plasticity and learning in a mouse model of tuberous sclerosis complex.

Zeng LH, Ouyang Y, Gazit V, Cirrito JR, Jansen LA, Ess KC, Yamada KA, Wozniak DF, Holtzman DM, Gutmann DH, Wong M.

Neurobiol Dis. 2007 Nov;28(2):184-96. Epub 2007 Jul 21.

39.

The neurobiology of tuberous sclerosis complex.

Ess KC.

Semin Pediatr Neurol. 2006 Mar;13(1):37-42. Review.

PMID:
16818174
40.

Developmental origin of subependymal giant cell astrocytoma in tuberous sclerosis complex.

Ess KC, Kamp CA, Tu BP, Gutmann DH.

Neurology. 2005 Apr 26;64(8):1446-9.

PMID:
15851742
41.

[Preserving independence in old age].

Waffenschmidt T, Ess K.

Krankenpfl Soins Infirm. 2005;98(1):20-1. German. No abstract available.

PMID:
15697031
42.

Expression profiling in tuberous sclerosis complex (TSC) knockout mouse astrocytes to characterize human TSC brain pathology.

Ess KC, Uhlmann EJ, Li W, Li H, Declue JE, Crino PB, Gutmann DH.

Glia. 2004 Apr 1;46(1):28-40.

PMID:
14999811
43.

Impaired glial glutamate transport in a mouse tuberous sclerosis epilepsy model.

Wong M, Ess KC, Uhlmann EJ, Jansen LA, Li W, Crino PB, Mennerick S, Yamada KA, Gutmann DH.

Ann Neurol. 2003 Aug;54(2):251-6.

PMID:
12891680
44.

Cerebrospinal fluid neuron-specific enolase following seizures in children: role of etiology.

Wong M, Ess K, Landt M.

J Child Neurol. 2002 Apr;17(4):261-4.

PMID:
12088080
45.
46.

A central role for a single c-Myb binding site in a thymic locus control region.

Ess KC, Whitaker TL, Cost GJ, Witte DP, Hutton JJ, Aronow BJ.

Mol Cell Biol. 1995 Oct;15(10):5707-15.

47.

Suppression of tumorigenicity, but not invasion, in glioblastoma/HeLa cell hybrids.

Ess K, Chen H, Kier A, Brackenbury R.

J Cell Physiol. 1995 Mar;162(3):341-7.

PMID:
7860642
48.

Winner of the Theodore E. Woodward Award: c-Myb and the coordinate regulation of thymic genes.

Hutton JJ, Ess KC, Witte DP, Aronow BJ.

Trans Am Clin Climatol Assoc. 1996;107:115-24. Review. No abstract available.

49.

Double-stranded phosphorothioate oligonucleotide modulation of gene expression.

Ess KC, Hutton JJ, Aronow BJ.

Ann N Y Acad Sci. 1994 May 31;716:321-3. No abstract available.

PMID:
8024203

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