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Items: 1 to 50 of 82

1.

Interaction of mycobacteria with Plasmin(ogen) affects phagocytosis and granuloma development.

Echeverría-Valencia G, Silva-Miranda M, Ekaza E, Vallecillo AJ, Parada C, Sada-Ovalle I, Altare F, Espitia C.

Tuberculosis (Edinb). 2019 Jul;117:36-44. doi: 10.1016/j.tube.2019.05.008. Epub 2019 Jun 1.

PMID:
31378266
2.

The novel autophagy inhibitor ROC-325 augments the antileukemic activity of azacitidine.

Nawrocki ST, Han Y, Visconte V, Przychodzen B, Espitia CM, Phillips J, Anwer F, Advani A, Carraway HE, Kelly KR, Sekeres MA, Maciejewski JP, Carew JS.

Leukemia. 2019 Jul 29. doi: 10.1038/s41375-019-0529-2. [Epub ahead of print] No abstract available.

PMID:
31358855
3.

Heightened JNK Activation and Reduced XIAP Levels Promote TRAIL and Sunitinib-Mediated Apoptosis in Colon Cancer Models.

Mahalingam D, Carew JS, Espitia CM, Cool RH, Giles FJ, de Jong S, Nawrocki ST.

Cancers (Basel). 2019 Jun 26;11(7). pii: E895. doi: 10.3390/cancers11070895.

4.

Moderate protection is induced by a chimeric protein composed of leucine aminopeptidase and cathepsin L1 against Fasciola hepatica challenge in sheep.

Ortega-Vargas S, Espitia C, Sahagún-Ruiz A, Parada C, Balderas-Loaeza A, Villa-Mancera A, Quiroz-Romero H.

Vaccine. 2019 May 27;37(24):3234-3240. doi: 10.1016/j.vaccine.2019.04.067. Epub 2019 Apr 26.

PMID:
31036453
5.

Rational cotargeting of HDAC6 and BET proteins yields synergistic antimyeloma activity.

Carew JS, Espitia CM, Zhao W, Visconte V, Anwer F, Kelly KR, Nawrocki ST.

Blood Adv. 2019 Apr 23;3(8):1318-1329. doi: 10.1182/bloodadvances.2018026484.

6.

Recombinant O-mannosylated protein production (PstS-1) from Mycobacterium tuberculosis in Pichia pastoris (Komagataella phaffii) as a tool to study tuberculosis infection.

Bando-Campos G, Juárez-López D, Román-González SA, Castillo-Rodal AI, Olvera C, López-Vidal Y, Arreguín-Espinosa R, Espitia C, Trujillo-Roldán MA, Valdez-Cruz NA.

Microb Cell Fact. 2019 Jan 19;18(1):11. doi: 10.1186/s12934-019-1059-3.

7.

LprG and PE_PGRS33 Mycobacterium tuberculosis virulence factors induce differential mitochondrial dynamics in macrophages.

Aguilar-López BA, Correa F, Moreno-Altamirano MMB, Espitia C, Hernández-Longoria R, Oliva-Ramírez J, Padierna-Olivos J, Sánchez-García FJ.

Scand J Immunol. 2019 Jan;89(1):e12728. doi: 10.1111/sji.12728. Epub 2018 Nov 30.

PMID:
30375016
8.

Identification and characterization of Taenia solium enolase as a plasminogen-binding protein.

Ayón-Núñez DA, Fragoso G, Espitia C, García-Varela M, Soberón X, Rosas G, Laclette JP, Bobes RJ.

Acta Trop. 2018 Jun;182:69-79. doi: 10.1016/j.actatropica.2018.02.020. Epub 2018 Feb 18.

PMID:
29466706
9.

Mexican Propolis: A Source of Antioxidants and Anti-Inflammatory Compounds, and Isolation of a Novel Chalcone and ε-Caprolactone Derivative.

Guzmán-Gutiérrez SL, Nieto-Camacho A, Castillo-Arellano JI, Huerta-Salazar E, Hernández-Pasteur G, Silva-Miranda M, Argüello-Nájera O, Sepúlveda-Robles O, Espitia CI, Reyes-Chilpa R.

Molecules. 2018 Feb 6;23(2). pii: E334. doi: 10.3390/molecules23020334.

10.

Oncolytic reovirus inhibits angiogenesis through induction of CXCL10/IP-10 and abrogation of HIF activity in soft tissue sarcomas.

Carew JS, Espitia CM, Zhao W, Mita MM, Mita AC, Nawrocki ST.

Oncotarget. 2017 Sep 30;8(49):86769-86783. doi: 10.18632/oncotarget.21423. eCollection 2017 Oct 17.

11.

Oncolytic reovirus sensitizes multiple myeloma cells to anti-PD-L1 therapy.

Kelly KR, Espitia CM, Zhao W, Wu K, Visconte V, Anwer F, Calton CM, Carew JS, Nawrocki ST.

Leukemia. 2018 Jan;32(1):230-233. doi: 10.1038/leu.2017.272. Epub 2017 Aug 23. No abstract available.

12.

The sigma factor SigD of Mycobacterium tuberculosis putatively enhances gene expression of the septum site determining protein under stressful environments.

Ares MA, Rios-Sarabia N, De la Cruz MA, Rivera-Gutiérrez S, García-Morales L, León-Solís L, Espitia C, Pacheco S, Cerna-Cortés JF, Helguera-Repetto CA, García MJ, González-Y-Merchand JA.

New Microbiol. 2017 Jul;40(3):199-204. Epub 2017 Jul 4.

13.

Erratum to: Rhodococcus erythropolis as a host for expression, secretion and glycosylation of Mycobacterium tuberculosis proteins.

Vallecillo AJ, Parada C, Morales P, Espitia C.

Microb Cell Fact. 2017 Apr 19;16(1):65. doi: 10.1186/s12934-017-0672-2. No abstract available.

14.

Effect of Bacterial Biofilm on the Osteogenic Differentiation of Stem Cells of Apical Papilla.

Vishwanat L, Duong R, Takimoto K, Phillips L, Espitia CO, Diogenes A, Ruparel SB, Kolodrubetz D, Ruparel NB.

J Endod. 2017 Jun;43(6):916-922. doi: 10.1016/j.joen.2017.01.023. Epub 2017 Apr 14.

PMID:
28416302
15.

Rhodococcus erythropolis as a host for expression, secretion and glycosylation of Mycobacterium tuberculosis proteins.

Vallecillo AJ, Parada C, Morales P, Espitia C.

Microb Cell Fact. 2017 Jan 19;16(1):12. doi: 10.1186/s12934-017-0628-6. Erratum in: Microb Cell Fact. 2017 Apr 19;16(1):65.

16.

Interaction of the CD43 Sialomucin with the Mycobacterium tuberculosis Cpn60.2 Chaperonin Leads to Tumor Necrosis Factor Alpha Production.

Torres-Huerta A, Villaseñor T, Flores-Alcantar A, Parada C, Alemán-Navarro E, Espitia C, Pedraza-Alva G, Rosenstein Y.

Infect Immun. 2017 Feb 23;85(3). pii: e00915-16. doi: 10.1128/IAI.00915-16. Print 2017 Mar.

17.

Active tuberculosis patients have high levels of IgA anti-alpha-crystallin and isocitrate lyase proteins.

Talavera-Paulín M, García-Morales L, Ruíz-Sánchez BP, Caamal-Ley ÁD, Hernández-Solis A, Ramírez-Casanova E, Cicero-Sabido R, Espitia C, Helguera-Repetto C, González-Y-Merchand JA, Flores-Mejía R, Estrada-Parra S, Estrada-García I, Chacón-Salinas R, Wong-Baeza I, Serafín-López J.

Int J Tuberc Lung Dis. 2016 Dec 1;20(12):1681-1688. doi: 10.5588/ijtld.16.0250.

PMID:
28000588
18.

Disruption of Autophagic Degradation with ROC-325 Antagonizes Renal Cell Carcinoma Pathogenesis.

Carew JS, Espitia CM, Zhao W, Han Y, Visconte V, Phillips J, Nawrocki ST.

Clin Cancer Res. 2017 Jun 1;23(11):2869-2879. doi: 10.1158/1078-0432.CCR-16-1742. Epub 2016 Nov 23.

19.

A rapid alternative method to evaluate T-cell hybridoma activation using an improved cytokine (IL-2) secretion assay.

Gastelum-Aviña P, Lares-Villa F, Espitia C, Valenzuela O, Robles-Zepeda R, Velazquez C, Garibay-Escobar A.

J Immunol Methods. 2016 Nov;438:42-50. doi: 10.1016/j.jim.2016.08.011. Epub 2016 Aug 31.

PMID:
27592266
20.

Antibody Persistence in Adults Two Years after Vaccination with an H1N1 2009 Pandemic Influenza Virus-Like Particle Vaccine.

Valero-Pacheco N, Pérez-Toledo M, Villasís-Keever MÁ, Núñez-Valencia A, Boscó-Gárate I, Lozano-Dubernard B, Lara-Puente H, Espitia C, Alpuche-Aranda C, Bonifaz LC, Arriaga-Pizano L, Pastelin-Palacios R, Isibasi A, López-Macías C.

PLoS One. 2016 Feb 26;11(2):e0150146. doi: 10.1371/journal.pone.0150146. eCollection 2016.

21.

Junctional adhesion molecule-A is overexpressed in advanced multiple myeloma and determines response to oncolytic reovirus.

Kelly KR, Espitia CM, Zhao W, Wendlandt E, Tricot G, Zhan F, Carew JS, Nawrocki ST.

Oncotarget. 2015 Dec 1;6(38):41275-89. doi: 10.18632/oncotarget.5753.

22.

Comprehensive quantitative proteomic profiling of the pharmacodynamic changes induced by MLN4924 in acute myeloid leukemia cells establishes rationale for its combination with azacitidine.

Visconte V, Nawrocki ST, Espitia CM, Kelly KR, Possemato A, Beausoleil SA, Han Y, Carraway HE, Nazha A, Advani AS, Maciejewski JP, Sekeres MA, Carew JS.

Leukemia. 2016 May;30(5):1190-4. doi: 10.1038/leu.2015.250. Epub 2015 Sep 15. No abstract available.

23.

Targeting Survivin Inhibits Renal Cell Carcinoma Progression and Enhances the Activity of Temsirolimus.

Carew JS, Espitia CM, Zhao W, Mita MM, Mita AC, Nawrocki ST.

Mol Cancer Ther. 2015 Jun;14(6):1404-13. doi: 10.1158/1535-7163.MCT-14-1036. Epub 2015 Mar 25.

24.

A PE_PGRS33 protein of Mycobacterium tuberculosis: an ideal target for future tuberculosis vaccine design.

Gastelum-Aviña P, Velazquez C, Espitia C, Lares-Villa F, Garibay-Escobar A.

Expert Rev Vaccines. 2015 May;14(5):699-711. doi: 10.1586/14760584.2015.1015995. Epub 2015 Feb 19. Review.

PMID:
25693607
25.

Transcriptional profiling of the spleen in progressive visceral leishmaniasis reveals mixed expression of type 1 and type 2 cytokine-responsive genes.

Espitia CM, Saldarriaga OA, Travi BL, Osorio EY, Hernandez A, Band M, Patel MJ, Medina AA, Cappello M, Pekosz A, Melby PC.

BMC Immunol. 2014 Nov 26;15:38. doi: 10.1186/s12865-014-0038-z.

26.

Starch granules as a vehicle for the oral administration of immobilized antigens.

Guillén D, Moreno-Mendieta S, Pérez R, Espitia C, Sánchez S, Rodríguez-Sanoja R.

Carbohydr Polym. 2014 Nov 4;112:210-5. doi: 10.1016/j.carbpol.2014.05.089. Epub 2014 Jun 6.

PMID:
25129737
27.

A novel antigen-carrier system: the Mycobacterium tuberculosis Acr protein carried by raw starch microparticles.

Moreno-Mendieta SA, Guillén D, Espitia C, Hernández-Pando R, Sanchez S, Rodríguez-Sanoja R.

Int J Pharm. 2014 Oct 20;474(1-2):241-8. doi: 10.1016/j.ijpharm.2014.07.041. Epub 2014 Aug 2.

PMID:
25093695
28.

Combined autophagy and HDAC inhibition: a phase I safety, tolerability, pharmacokinetic, and pharmacodynamic analysis of hydroxychloroquine in combination with the HDAC inhibitor vorinostat in patients with advanced solid tumors.

Mahalingam D, Mita M, Sarantopoulos J, Wood L, Amaravadi RK, Davis LE, Mita AC, Curiel TJ, Espitia CM, Nawrocki ST, Giles FJ, Carew JS.

Autophagy. 2014 Aug;10(8):1403-14. doi: 10.4161/auto.29231. Epub 2014 May 20.

29.

The PGRS Domain from PE_PGRS33 of Mycobacterium tuberculosis is Target of Humoral Immune Response in Mice and Humans.

Cohen I, Parada C, Acosta-Gío E, Espitia C.

Front Immunol. 2014 May 27;5:236. doi: 10.3389/fimmu.2014.00236. eCollection 2014.

30.

Lipoprotein N-acyl transferase (Lnt1) is dispensable for protein O-mannosylation by Streptomyces coelicolor.

Córdova-Dávalos LE, Espitia C, González-Cerón G, Arreguín-Espinosa R, Soberón-Chávez G, Servín-González L.

FEMS Microbiol Lett. 2014 Jan;350(1):72-82. doi: 10.1111/1574-6968.12298. Epub 2013 Oct 25.

31.

Reolysin is a novel reovirus-based agent that induces endoplasmic reticular stress-mediated apoptosis in pancreatic cancer.

Carew JS, Espitia CM, Zhao W, Kelly KR, Coffey M, Freeman JW, Nawrocki ST.

Cell Death Dis. 2013 Jul 18;4:e728. doi: 10.1038/cddis.2013.259.

32.

Disrupting protein NEDDylation with MLN4924 is a novel strategy to target cisplatin resistance in ovarian cancer.

Nawrocki ST, Kelly KR, Smith PG, Espitia CM, Possemato A, Beausoleil SA, Milhollen M, Blakemore S, Thomas M, Berger A, Carew JS.

Clin Cancer Res. 2013 Jul 1;19(13):3577-90. doi: 10.1158/1078-0432.CCR-12-3212. Epub 2013 Apr 30.

33.

Scale-up from shake flasks to bioreactor, based on power input and Streptomyces lividans morphology, for the production of recombinant APA (45/47 kDa protein) from Mycobacterium tuberculosis.

Gamboa-Suasnavart RA, Marín-Palacio LD, Martínez-Sotelo JA, Espitia C, Servín-González L, Valdez-Cruz NA, Trujillo-Roldán MA.

World J Microbiol Biotechnol. 2013 Aug;29(8):1421-9. doi: 10.1007/s11274-013-1305-5. Epub 2013 Mar 10.

PMID:
23475258
34.

Bioinformatic identification of Mycobacterium tuberculosis proteins likely to target host cell mitochondria: virulence factors?

Moreno-Altamirano MM, Paredes-González IS, Espitia C, Santiago-Maldonado M, Hernández-Pando R, Sánchez-García FJ.

Microb Inform Exp. 2012 Dec 22;2(1):9. doi: 10.1186/2042-5783-2-9.

35.

The response of the fibrinolytic system to mycobacteria infection.

Rodríguez-Flores E, Campuzano J, Aguilar D, Hernández-Pando R, Espitia C.

Tuberculosis (Edinb). 2012 Nov;92(6):497-504. doi: 10.1016/j.tube.2012.07.002. Epub 2012 Aug 11.

PMID:
22885283
36.

Targeting Aurora A kinase activity with the investigational agent alisertib increases the efficacy of cytarabine through a FOXO-dependent mechanism.

Kelly KR, Nawrocki ST, Espitia CM, Zhang M, Yang JJ, Padmanabhan S, Ecsedy J, Giles FJ, Carew JS.

Int J Cancer. 2012 Dec 1;131(11):2693-703. doi: 10.1002/ijc.27579. Epub 2012 Jun 28.

37.

Specificity of the tuberculin skin test is modified by use of a protein cocktail containing ESAT-6 and CFP-10 in cattle naturally infected with Mycobacterium bovis.

Flores-Villalva S, Suárez-Güemes F, Espitia C, Whelan AO, Vordermeier M, Gutiérrez-Pabello JA.

Clin Vaccine Immunol. 2012 May;19(5):797-803. doi: 10.1128/CVI.05668-11. Epub 2012 Mar 14.

38.

ELR510444 inhibits tumor growth and angiogenesis by abrogating HIF activity and disrupting microtubules in renal cell carcinoma.

Carew JS, Esquivel JA 2nd, Espitia CM, Schultes CM, Mülbaier M, Lewis JD, Janssen B, Giles FJ, Nawrocki ST.

PLoS One. 2012;7(1):e31120. doi: 10.1371/journal.pone.0031120. Epub 2012 Jan 25.

39.

Progressive visceral leishmaniasis is driven by dominant parasite-induced STAT6 activation and STAT6-dependent host arginase 1 expression.

Osorio EY, Zhao W, Espitia C, Saldarriaga O, Hawel L, Byus CV, Travi BL, Melby PC.

PLoS Pathog. 2012 Jan;8(1):e1002417. doi: 10.1371/journal.ppat.1002417. Epub 2012 Jan 19.

40.

The O-mannosylation and production of recombinant APA (45/47 KDa) protein from Mycobacterium tuberculosis in Streptomyces lividans is affected by culture conditions in shake flasks.

Gamboa-Suasnavart RA, Valdez-Cruz NA, Cordova-Dávalos LE, Martínez-Sotelo JA, Servín-González L, Espitia C, Trujillo-Roldán MA.

Microb Cell Fact. 2011 Dec 20;10:110. doi: 10.1186/1475-2859-10-110.

41.

Targeting PIM kinase enhances the activity of sunitinib in renal cell carcinoma.

Mahalingam D, Espitia CM, Medina EC, Esquivel JA 2nd, Kelly KR, Bearss D, Choy G, Taverna P, Carew JS, Giles FJ, Nawrocki ST.

Br J Cancer. 2011 Nov 8;105(10):1563-73. doi: 10.1038/bjc.2011.426. Epub 2011 Oct 20.

42.

Reovirus therapy stimulates endoplasmic reticular stress, NOXA induction, and augments bortezomib-mediated apoptosis in multiple myeloma.

Kelly KR, Espitia CM, Mahalingam D, Oyajobi BO, Coffey M, Giles FJ, Carew JS, Nawrocki ST.

Oncogene. 2012 Jun 21;31(25):3023-38. doi: 10.1038/onc.2011.478. Epub 2011 Oct 17.

PMID:
22002308
43.

Targeting PIM kinase activity significantly augments the efficacy of cytarabine.

Kelly KR, Espitia CM, Taverna P, Choy G, Padmanabhan S, Nawrocki ST, Giles FJ, Carew JS.

Br J Haematol. 2012 Jan;156(1):129-32. doi: 10.1111/j.1365-2141.2011.08792.x. Epub 2011 Jun 21. No abstract available.

PMID:
21689092
44.

Tuberculosis transmission across the United States-Mexico border.

Fitchett JR, Vallecillo AJ, Espitia C.

Rev Panam Salud Publica. 2011 Jan;29(1):57-60.

PMID:
21390421
45.

Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis.

Carew JS, Espitia CM, Esquivel JA 2nd, Mahalingam D, Kelly KR, Reddy G, Giles FJ, Nawrocki ST.

J Biol Chem. 2011 Feb 25;286(8):6602-13. doi: 10.1074/jbc.M110.151324. Epub 2010 Dec 10.

46.

Detection of bovine tuberculosis in herds with different disease prevalence and influence of paratuberculosis infection on PPDB and ESAT-6/CFP10 specificity.

Aagaard C, Govaerts M, Meikle V, Gutiérrez-Pabello JA, McNair J, Andersen P, Suárez-Güemes F, Pollock J, Espitia C, Cataldi A.

Prev Vet Med. 2010 Sep 1;96(3-4):161-9. doi: 10.1016/j.prevetmed.2010.06.007. Epub 2010 Jul 14.

PMID:
20630607
47.

Specific bacterial genotypes of Mycobacterium tuberculosis cause extensive dissemination and brain infection in an experimental model.

Hernandez Pando R, Aguilar D, Cohen I, Guerrero M, Ribon W, Acosta P, Orozco H, Marquina B, Salinas C, Rembao D, Espitia C.

Tuberculosis (Edinb). 2010 Jul;90(4):268-77. doi: 10.1016/j.tube.2010.05.002. Epub 2010 Jun 30.

PMID:
20580613
48.

Duplex real-time reverse transcriptase PCR to determine cytokine mRNA expression in a hamster model of New World cutaneous leishmaniasis.

Espitia CM, Zhao W, Saldarriaga O, Osorio Y, Harrison LM, Cappello M, Travi BL, Melby PC.

BMC Immunol. 2010 Jun 22;11:31. doi: 10.1186/1471-2172-11-31.

49.

New insights into protein O-mannosylation in actinomycetes.

Espitia C, Servín-González L, Mancilla R.

Mol Biosyst. 2010 May;6(5):775-81. doi: 10.1039/b916394h. Epub 2010 Feb 24. Review.

PMID:
20567761
50.

Vorinostat enhances the activity of temsirolimus in renal cell carcinoma through suppression of survivin levels.

Mahalingam D, Medina EC, Esquivel JA 2nd, Espitia CM, Smith S, Oberheu K, Swords R, Kelly KR, Mita MM, Mita AC, Carew JS, Giles FJ, Nawrocki ST.

Clin Cancer Res. 2010 Jan 1;16(1):141-53. doi: 10.1158/1078-0432.CCR-09-1385. Epub 2009 Dec 22.

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