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Items: 1 to 50 of 109

1.

Inferring trophic groups of fish in the central-east Atlantic from eco-toxicological characterization.

Lozano-Bilbao E, Clemente S, Espinosa JM, Jurado-Ruzafa A, Lozano G, Raimundo J, Hardisson A, Rubio C, González-Weller D, Jiménez S, Gutiérrez ÁJ.

Chemosphere. 2019 Aug;229:247-255. doi: 10.1016/j.chemosphere.2019.04.218. Epub 2019 May 1.

PMID:
31078881
2.

Late toxicity after single dose HDR prostate brachytherapy and EBRT for localized prostate cancer: Clinical and dosimetric predictors in a prospective cohort study.

Büchser D, Casquero F, Espinosa JM, Perez F, Minguez P, Martinez-Indart L, Suarez F, Gonzalez A, Cacicedo J, San Miguel I, Maleta A, Gomez-Caamaño A, Bilbao P, Gomez-Iturriaga A.

Radiother Oncol. 2019 Jun;135:13-18. doi: 10.1016/j.radonc.2019.02.018. Epub 2019 Mar 5.

PMID:
31015158
3.

Janus kinase inhibition in Down syndrome: 2 cases of therapeutic benefit for alopecia areata.

Rachubinski AL, Estrada BE, Norris D, Dunnick CA, Boldrick JC, Espinosa JM.

JAAD Case Rep. 2019 Apr 5;5(4):365-367. doi: 10.1016/j.jdcr.2019.02.007. eCollection 2019 Apr. No abstract available.

4.

Transcriptional CDKs in the spotlight.

Espinosa JM.

Transcription. 2019 Apr;10(2):45-46. doi: 10.1080/21541264.2019.1597479. No abstract available.

PMID:
30946639
5.

SIX2 Mediates Late-Stage Metastasis via Direct Regulation of SOX2 and Induction of a Cancer Stem Cell Program.

Oliphant MUJ, Vincent MY, Galbraith MD, Pandey A, Zaberezhnyy V, Rudra P, Johnson KR, Costello JC, Ghosh D, DeGregori J, Espinosa JM, Ford HL.

Cancer Res. 2019 Feb 15;79(4):720-734. doi: 10.1158/0008-5472.CAN-18-1791. Epub 2019 Jan 3.

PMID:
30606720
6.

[Effective implementation of the Quadruple Helix-Based Innovation Model for active ageing].

Padial M, Pinzón S, Navarro B, San Juan P, Ruiz J, Espinosa JM.

Gac Sanit. 2018 Nov 29. pii: S0213-9111(18)30224-3. doi: 10.1016/j.gaceta.2018.08.003. [Epub ahead of print] Spanish.

7.

Therapeutic targeting of transcriptional cyclin-dependent kinases.

Galbraith MD, Bender H, Espinosa JM.

Transcription. 2019 Apr;10(2):118-136. doi: 10.1080/21541264.2018.1539615. Epub 2018 Nov 9. Review.

8.

ΔNp63α Suppresses TGFB2 Expression and RHOA Activity to Drive Cell Proliferation in Squamous Cell Carcinomas.

Abraham CG, Ludwig MP, Andrysik Z, Pandey A, Joshi M, Galbraith MD, Sullivan KD, Espinosa JM.

Cell Rep. 2018 Sep 18;24(12):3224-3236. doi: 10.1016/j.celrep.2018.08.058.

9.

Trisomy 21 Represses Cilia Formation and Function.

Galati DF, Sullivan KD, Pham AT, Espinosa JM, Pearson CG.

Dev Cell. 2018 Sep 10;46(5):641-650.e6. doi: 10.1016/j.devcel.2018.07.008. Epub 2018 Aug 9.

PMID:
30100262
10.

Zinc Finger Protein 521 Regulates Early Hematopoiesis through Cell-Extrinsic Mechanisms in the Bone Marrow Microenvironment.

Fleenor CJ, Arends T, Lei H, Åhsberg J, Okuyama K, Kuruvilla J, Cristobal S, Rabe JL, Pandey A, Danhorn T, Straign D, Espinosa JM, Warming S, Pietras EM, Sigvardsson M, Hagman JR.

Mol Cell Biol. 2018 Aug 15;38(17). pii: e00603-17. doi: 10.1128/MCB.00603-17. Print 2018 Sep 1.

11.

Adaptive changes in global gene expression profile of lung carcinoma A549 cells acutely exposed to distinct types of AhR ligands.

Procházková J, Strapáčová S, Svržková L, Andrysík Z, Hýžďalová M, Hrubá E, Pěnčíková K, Líbalová H, Topinka J, Kléma J, Espinosa JM, Vondráček J, Machala M.

Toxicol Lett. 2018 Aug;292:162-174. doi: 10.1016/j.toxlet.2018.04.024. Epub 2018 Apr 25.

PMID:
29704546
12.

The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L.

Guarnieri AL, Towers CG, Drasin DJ, Oliphant MUJ, Andrysik Z, Hotz TJ, Vartuli RL, Linklater ES, Pandey A, Khanal S, Espinosa JM, Ford HL.

Oncogene. 2018 Jul;37(28):3879-3893. doi: 10.1038/s41388-018-0239-7. Epub 2018 Apr 17.

13.

Guideline on cochlear implants.

Manrique M, Ramos Á, de Paula Vernetta C, Gil-Carcedo E, Lassaletta L, Sanchez-Cuadrado I, Espinosa JM, Batuecas Á, Cenjor C, Lavilla MJ, Núñez F, Cavalle L, Huarte A.

Acta Otorrinolaringol Esp. 2019 Jan - Feb;70(1):47-54. doi: 10.1016/j.otorri.2017.10.007. Epub 2018 Mar 26. English, Spanish.

14.

Active middle ear implants.

Lassaletta L, Sánchez-Cuadrado I, Espinosa JM, Batuecas Á, Cenjor C, Lavilla MJ, Cavallé L, Huarte A, Nuñez F, Manrique M, Ramos Á, de Paula C, Gil-Carcedo E.

Acta Otorrinolaringol Esp. 2019 Mar - Apr;70(2):112-118. doi: 10.1016/j.otorri.2017.10.001. Epub 2018 Mar 17. English, Spanish.

15.

Autophagy Inhibition Mediates Apoptosis Sensitization in Cancer Therapy by Relieving FOXO3a Turnover.

Fitzwalter BE, Towers CG, Sullivan KD, Andrysik Z, Hoh M, Ludwig M, O'Prey J, Ryan KM, Espinosa JM, Morgan MJ, Thorburn A.

Dev Cell. 2018 Mar 12;44(5):555-565.e3. doi: 10.1016/j.devcel.2018.02.014.

16.

Red blood cell metabolism in Down syndrome: hints on metabolic derangements in aging.

Culp-Hill R, Zheng C, Reisz JA, Smith K, Rachubinski A, Nemkov T, Butcher E, Granrath R, Hansen KC, Espinosa JM, D'Alessandro A.

Blood Adv. 2017 Dec 21;1(27):2776-2780. doi: 10.1182/bloodadvances.2017011957. eCollection 2017 Dec 26.

17.

Health-related-quality-of-life and toxicity after single fraction 19 Gy high-dose-rate prostate brachytherapy: Phase II trial.

Gomez-Iturriaga A, Casquero F, Pijoan JI, Minguez P, Espinosa JM, Irasarri A, Bueso A, Cacicedo J, Buchser D, Bilbao P.

Radiother Oncol. 2018 Feb;126(2):278-282. doi: 10.1016/j.radonc.2017.10.039. Epub 2017 Nov 15.

PMID:
29153462
18.

Mechanisms of transcriptional regulation by p53.

Sullivan KD, Galbraith MD, Andrysik Z, Espinosa JM.

Cell Death Differ. 2018 Jan;25(1):133-143. doi: 10.1038/cdd.2017.174. Epub 2017 Nov 10. Review.

19.

CDK8 Kinase Activity Promotes Glycolysis.

Galbraith MD, Andrysik Z, Pandey A, Hoh M, Bonner EA, Hill AA, Sullivan KD, Espinosa JM.

Cell Rep. 2017 Nov 7;21(6):1495-1506. doi: 10.1016/j.celrep.2017.10.058.

20.

Trisomy 21 causes changes in the circulating proteome indicative of chronic autoinflammation.

Sullivan KD, Evans D, Pandey A, Hraha TH, Smith KP, Markham N, Rachubinski AL, Wolter-Warmerdam K, Hickey F, Espinosa JM, Blumenthal T.

Sci Rep. 2017 Nov 1;7(1):14818. doi: 10.1038/s41598-017-13858-3.

21.

Influence of the submarine volcanic eruption off El Hierro (Canary Islands) on the mesopelagic cephalopod's metal content.

Lozano-Bilbao E, Gutiérrez ÁJ, Hardisson A, Rubio C, González-Weller D, Aguilar N, Escánez A, Espinosa JM, Canales P, Lozano G.

Mar Pollut Bull. 2018 Apr;129(2):474-479. doi: 10.1016/j.marpolbul.2017.10.017. Epub 2017 Oct 21.

PMID:
29033169
22.

Identification of a core TP53 transcriptional program with highly distributed tumor suppressive activity.

Andrysik Z, Galbraith MD, Guarnieri AL, Zaccara S, Sullivan KD, Pandey A, MacBeth M, Inga A, Espinosa JM.

Genome Res. 2017 Oct;27(10):1645-1657. doi: 10.1101/gr.220533.117. Epub 2017 Sep 13.

23.

Exosomal biomarkers in Down syndrome and Alzheimer's disease.

Hamlett ED, Ledreux A, Potter H, Chial HJ, Patterson D, Espinosa JM, Bettcher BM, Granholm AC.

Free Radic Biol Med. 2018 Jan;114:110-121. doi: 10.1016/j.freeradbiomed.2017.08.028. Epub 2017 Sep 5. Review.

24.

On the Origin of lncRNAs: Missing Link Found.

Espinosa JM.

Trends Genet. 2017 Oct;33(10):660-662. doi: 10.1016/j.tig.2017.07.005. Epub 2017 Aug 1.

25.

A Kinase-Independent Role for Cyclin-Dependent Kinase 19 in p53 Response.

Audetat KA, Galbraith MD, Odell AT, Lee T, Pandey A, Espinosa JM, Dowell RD, Taatjes DJ.

Mol Cell Biol. 2017 Jun 15;37(13). pii: e00626-16. doi: 10.1128/MCB.00626-16. Print 2017 Jul 1.

26.

Therapeutic Targeting of MLL Degradation Pathways in MLL-Rearranged Leukemia.

Liang K, Volk AG, Haug JS, Marshall SA, Woodfin AR, Bartom ET, Gilmore JM, Florens L, Washburn MP, Sullivan KD, Espinosa JM, Cannova J, Zhang J, Smith ER, Crispino JD, Shilatifard A.

Cell. 2017 Jan 12;168(1-2):59-72.e13. doi: 10.1016/j.cell.2016.12.011. Epub 2017 Jan 5.

27.

Multivalent Chromatin Engagement and Inter-domain Crosstalk Regulate MORC3 ATPase.

Andrews FH, Tong Q, Sullivan KD, Cornett EM, Zhang Y, Ali M, Ahn J, Pandey A, Guo AH, Strahl BD, Costello JC, Espinosa JM, Rothbart SB, Kutateladze TG.

Cell Rep. 2016 Sep 20;16(12):3195-3207. doi: 10.1016/j.celrep.2016.08.050.

28.

Trisomy 21 consistently activates the interferon response.

Sullivan KD, Lewis HC, Hill AA, Pandey A, Jackson LP, Cabral JM, Smith KP, Liggett LA, Gomez EB, Galbraith MD, DeGregori J, Espinosa JM.

Elife. 2016 Jul 29;5. pii: e16220. doi: 10.7554/eLife.16220.

29.

The NSL Chromatin-Modifying Complex Subunit KANSL2 Regulates Cancer Stem-like Properties in Glioblastoma That Contribute to Tumorigenesis.

Ferreyra Solari NE, Belforte FS, Canedo L, Videla-Richardson GA, Espinosa JM, Rossi M, Serna E, Riudavets MA, Martinetto H, Sevlever G, Perez-Castro C.

Cancer Res. 2016 Sep 15;76(18):5383-94. doi: 10.1158/0008-5472.CAN-15-3159. Epub 2016 Jul 12.

30.

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

Perez-Perri JI, Dengler VL, Audetat KA, Pandey A, Bonner EA, Urh M, Mendez J, Daniels DL, Wappner P, Galbraith MD, Espinosa JM.

Cell Rep. 2016 Jun 28;16(1):37-47. doi: 10.1016/j.celrep.2016.05.082. Epub 2016 Jun 16.

31.

Revisiting lncRNAs: How Do You Know Yours Is Not an eRNA?

Espinosa JM.

Mol Cell. 2016 Apr 7;62(1):1-2. doi: 10.1016/j.molcel.2016.03.022.

32.

NPM and BRG1 Mediate Transcriptional Resistance to Retinoic Acid in Acute Promyelocytic Leukemia.

Nichol JN, Galbraith MD, Kleinman CL, Espinosa JM, Miller WH Jr.

Cell Rep. 2016 Mar 29;14(12):2938-49. doi: 10.1016/j.celrep.2016.02.074. Epub 2016 Mar 17.

33.

Dose escalation to dominant intraprostatic lesions with MRI-transrectal ultrasound fusion High-Dose-Rate prostate brachytherapy. Prospective phase II trial.

Gomez-Iturriaga A, Casquero F, Urresola A, Ezquerro A, Lopez JI, Espinosa JM, Minguez P, Llarena R, Irasarri A, Bilbao P, Crook J.

Radiother Oncol. 2016 Apr;119(1):91-6. doi: 10.1016/j.radonc.2016.02.004. Epub 2016 Feb 15.

PMID:
26900090
34.

The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p.

Towers CG, Guarnieri AL, Micalizzi DS, Harrell JC, Gillen AE, Kim J, Wang CA, Oliphant MUJ, Drasin DJ, Guney MA, Kabos P, Sartorius CA, Tan AC, Perou CM, Espinosa JM, Ford HL.

Nat Commun. 2015 Dec 21;6:10077. doi: 10.1038/ncomms10077.

35.

The Crusade against Mutant p53: Does the COMPASS Point to the Holy Grail?

Abraham CG, Espinosa JM.

Cancer Cell. 2015 Oct 12;28(4):407-408. doi: 10.1016/j.ccell.2015.09.019.

36.

A signature for success.

Espinosa JM, Sullivan KD.

Elife. 2015 Jun 16;4. doi: 10.7554/eLife.08773.

37.

Should PET/CT be implemented in the routine imaging work-up of locally advanced head and neck squamous cell carcinoma? A prospective analysis.

Cacicedo J, Fernandez I, Del Hoyo O, Dolado A, Gómez-Suarez J, Hortelano E, Sancho A, Pijoan JI, Alvarez J, Espinosa JM, Gaafar A, Bilbao P.

Eur J Nucl Med Mol Imaging. 2015 Aug;42(9):1378-89. doi: 10.1007/s00259-015-3071-0. Epub 2015 May 8.

PMID:
25952280
38.

Human ACAP2 is a homolog of C. elegans CNT-1 that promotes apoptosis in cancer cells.

Sullivan KD, Nakagawa A, Xue D, Espinosa JM.

Cell Cycle. 2015;14(12):1771-8. doi: 10.1080/15384101.2015.1026518.

39.

p53 Family Members Regulate Phenotypic Response to Aurora Kinase A Inhibition in Triple-Negative Breast Cancer.

Tentler JJ, Ionkina AA, Tan AC, Newton TP, Pitts TM, Glogowska MJ, Kabos P, Sartorius CA, Sullivan KD, Espinosa JM, Eckhardt SG, Diamond JR.

Mol Cancer Ther. 2015 May;14(5):1117-29. doi: 10.1158/1535-7163.MCT-14-0538-T. Epub 2015 Mar 10.

40.

Role of the host restriction factor APOBEC3 on papillomavirus evolution.

Warren CJ, Van Doorslaer K, Pandey A, Espinosa JM, Pyeon D.

Virus Evol. 2015 Jan;1(1). pii: vev015. Epub 2015 Jan 1.

41.

ATM regulates cell fate choice upon p53 activation by modulating mitochondrial turnover and ROS levels.

Sullivan KD, Palaniappan VV, Espinosa JM.

Cell Cycle. 2015;14(1):56-63. doi: 10.4161/15384101.2014.973330.

42.

Impact of intraoperative MRI/TRUS fusion on dosimetric parameters in cT3a prostate cancer patients treated with high-dose-rate real-time brachytherapy.

Gomez-Iturriaga A, Crook J, Casquero F, Carvajal C, Urresola A, Canteli B, Ezquerro A, Hortelano E, Cacicedo J, Espinosa JM, Perez F, Minguez P, Bilbao P.

J Contemp Brachytherapy. 2014 Jun;6(2):154-60. doi: 10.5114/jcb.2014.43299. Epub 2014 Jun 9.

43.

Global analysis of p53-regulated transcription identifies its direct targets and unexpected regulatory mechanisms.

Allen MA, Andrysik Z, Dengler VL, Mellert HS, Guarnieri A, Freeman JA, Sullivan KD, Galbraith MD, Luo X, Kraus WL, Dowell RD, Espinosa JM.

Elife. 2014 May 27;3:e02200. doi: 10.7554/eLife.02200.

44.

Autophagy controls the kinetics and extent of mitochondrial apoptosis by regulating PUMA levels.

Thorburn J, Andrysik Z, Staskiewicz L, Gump J, Maycotte P, Oberst A, Green DR, Espinosa JM, Thorburn A.

Cell Rep. 2014 Apr 10;7(1):45-52. doi: 10.1016/j.celrep.2014.02.036. Epub 2014 Mar 27.

45.

Back to bases: how a nucleotide biosynthetic enzyme controls p53 activation.

Guarnieri AL, Espinosa JM.

Mol Cell. 2014 Feb 6;53(3):365-7. doi: 10.1016/j.molcel.2014.01.025.

46.

Transcriptional regulation by hypoxia inducible factors.

Dengler VL, Galbraith M, Espinosa JM.

Crit Rev Biochem Mol Biol. 2014 Jan-Feb;49(1):1-15. doi: 10.3109/10409238.2013.838205. Epub 2013 Oct 7. Review.

47.

Inhibition of telomerase recruitment and cancer cell death.

Nakashima M, Nandakumar J, Sullivan KD, Espinosa JM, Cech TR.

J Biol Chem. 2013 Nov 15;288(46):33171-80. doi: 10.1074/jbc.M113.518175. Epub 2013 Oct 4.

48.

ERK phosphorylation of MED14 in promoter complexes during mitogen-induced gene activation by Elk-1.

Galbraith MD, Saxton J, Li L, Shelton SJ, Zhang H, Espinosa JM, Shaw PE.

Nucleic Acids Res. 2013 Dec;41(22):10241-53. doi: 10.1093/nar/gkt837. Epub 2013 Sep 17.

49.

A passive repression mechanism that hinders synergic transcriptional activation by heat shock factors involved in sunflower seed longevity.

Tejedor-Cano J, Carranco R, Personat JM, Prieto-Dapena P, Almoguera C, Espinosa JM, Jordano J.

Mol Plant. 2014 Jan;7(1):256-9. doi: 10.1093/mp/sst117. Epub 2013 Aug 17. No abstract available.

50.

HIF1A employs CDK8-mediator to stimulate RNAPII elongation in response to hypoxia.

Galbraith MD, Allen MA, Bensard CL, Wang X, Schwinn MK, Qin B, Long HW, Daniels DL, Hahn WC, Dowell RD, Espinosa JM.

Cell. 2013 Jun 6;153(6):1327-39. doi: 10.1016/j.cell.2013.04.048.

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