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Items: 22

1.

Increased serum sialic acid is associated with morbidity and mortality in a murine model of dengue disease.

Espinosa DA, Beatty PR, Puerta-Guardo H, Islam MN, Belisle JT, Perera R, Harris E.

J Gen Virol. 2019 Nov;100(11):1515-1522. doi: 10.1099/jgv.0.001319.

PMID:
31526452
2.

Endocytosis of flavivirus NS1 is required for NS1-mediated endothelial hyperpermeability and is abolished by a single N-glycosylation site mutation.

Wang C, Puerta-Guardo H, Biering SB, Glasner DR, Tran EB, Patana M, Gomberg TA, Malvar C, Lo NTN, Espinosa DA, Harris E.

PLoS Pathog. 2019 Jul 29;15(7):e1007938. doi: 10.1371/journal.ppat.1007938. eCollection 2019 Jul.

3.

Flavivirus NS1 Triggers Tissue-Specific Vascular Endothelial Dysfunction Reflecting Disease Tropism.

Puerta-Guardo H, Glasner DR, Espinosa DA, Biering SB, Patana M, Ratnasiri K, Wang C, Beatty PR, Harris E.

Cell Rep. 2019 Feb 5;26(6):1598-1613.e8. doi: 10.1016/j.celrep.2019.01.036.

4.

Cyclic Dinucleotide-Adjuvanted Dengue Virus Nonstructural Protein 1 Induces Protective Antibody and T Cell Responses.

Espinosa DA, Beatty PR, Reiner GL, Sivick KE, Hix Glickman L, Dubensky TW Jr, Harris E.

J Immunol. 2019 Feb 15;202(4):1153-1162. doi: 10.4049/jimmunol.1801323. Epub 2019 Jan 14.

PMID:
30642979
5.

Diagnosis of Zika Virus Infection by Peptide Array and Enzyme-Linked Immunosorbent Assay.

Mishra N, Caciula A, Price A, Thakkar R, Ng J, Chauhan LV, Jain K, Che X, Espinosa DA, Montoya Cruz M, Balmaseda A, Sullivan EH, Patel JJ, Jarman RG, Rakeman JL, Egan CT, Reusken CBEM, Koopmans MPG, Harris E, Tokarz R, Briese T, Lipkin WI.

MBio. 2018 Mar 6;9(2). pii: e00095-18. doi: 10.1128/mBio.00095-18.

6.

Dengue virus NS1 cytokine-independent vascular leak is dependent on endothelial glycocalyx components.

Glasner DR, Ratnasiri K, Puerta-Guardo H, Espinosa DA, Beatty PR, Harris E.

PLoS Pathog. 2017 Nov 9;13(11):e1006673. doi: 10.1371/journal.ppat.1006673. eCollection 2017 Nov.

7.

A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.

Wang J, Bardelli M, Espinosa DA, Pedotti M, Ng TS, Bianchi S, Simonelli L, Lim EXY, Foglierini M, Zatta F, Jaconi S, Beltramello M, Cameroni E, Fibriansah G, Shi J, Barca T, Pagani I, Rubio A, Broccoli V, Vicenzi E, Graham V, Pullan S, Dowall S, Hewson R, Jurt S, Zerbe O, Stettler K, Lanzavecchia A, Sallusto F, Cavalli A, Harris E, Lok SM, Varani L, Corti D.

Cell. 2017 Sep 21;171(1):229-241.e15. doi: 10.1016/j.cell.2017.09.002.

8.

Robust antibody and CD8+ T-cell responses induced by P. falciparum CSP adsorbed to cationic liposomal adjuvant CAF09 confer sterilizing immunity against experimental rodent malaria infection.

Espinosa DA, Christensen D, Muñoz C, Singh S, Locke E, Andersen P, Zavala F.

NPJ Vaccines. 2017;2. pii: 10. doi: 10.1038/s41541-017-0011-y. Epub 2017 Apr 10.

9.

A Prime/Boost PfCS14KM/MVA-sPfCSM Vaccination Protocol Generates Robust CD8+ T Cell and Antibody Responses to Plasmodium falciparum Circumsporozoite Protein and Protects Mice against Malaria.

Vijayan A, Mejías-Pérez E, Espinosa DA, Raman SC, Sorzano COS, Zavala F, Esteban M.

Clin Vaccine Immunol. 2017 May 5;24(5). pii: e00494-16. doi: 10.1128/CVI.00494-16. Print 2017 May.

10.

The Plasmodium falciparum Cell-Traversal Protein for Ookinetes and Sporozoites as a Candidate for Preerythrocytic and Transmission-Blocking Vaccines.

Espinosa DA, Vega-Rodriguez J, Flores-Garcia Y, Noe AR, Muñoz C, Coleman R, Bruck T, Haney K, Stevens A, Retallack D, Allen J, Vedvick TS, Fox CB, Reed SG, Howard RF, Salman AM, Janse CJ, Khan SM, Zavala F, Gutierrez GM.

Infect Immun. 2017 Jan 26;85(2). pii: e00498-16. doi: 10.1128/IAI.00498-16. Print 2017 Feb.

11.

Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection.

Stettler K, Beltramello M, Espinosa DA, Graham V, Cassotta A, Bianchi S, Vanzetta F, Minola A, Jaconi S, Mele F, Foglierini M, Pedotti M, Simonelli L, Dowall S, Atkinson B, Percivalle E, Simmons CP, Varani L, Blum J, Baldanti F, Cameroni E, Hewson R, Harris E, Lanzavecchia A, Sallusto F, Corti D.

Science. 2016 Aug 19;353(6301):823-6. doi: 10.1126/science.aaf8505. Epub 2016 Jul 14.

12.

Development and Assessment of Transgenic Rodent Parasites for the Preclinical Evaluation of Malaria Vaccines.

Espinosa DA, Radtke AJ, Zavala F.

Methods Mol Biol. 2016;1403:583-601. doi: 10.1007/978-1-4939-3387-7_33.

PMID:
27076155
13.

P. falciparum and P. vivax Epitope-Focused VLPs Elicit Sterile Immunity to Blood Stage Infections.

Whitacre DC, Espinosa DA, Peters CJ, Jones JE, Tucker AE, Peterson DL, Zavala FP, Milich DR.

PLoS One. 2015 May 1;10(5):e0124856. doi: 10.1371/journal.pone.0124856. eCollection 2015.

14.

Proteolytic Cleavage of the Plasmodium falciparum Circumsporozoite Protein Is a Target of Protective Antibodies.

Espinosa DA, Gutierrez GM, Rojas-López M, Noe AR, Shi L, Tse SW, Sinnis P, Zavala F.

J Infect Dis. 2015 Oct 1;212(7):1111-9. doi: 10.1093/infdis/jiv154. Epub 2015 Mar 11.

15.

Lymph-node resident CD8α+ dendritic cells capture antigens from migratory malaria sporozoites and induce CD8+ T cell responses.

Radtke AJ, Kastenmüller W, Espinosa DA, Gerner MY, Tse SW, Sinnis P, Germain RN, Zavala FP, Cockburn IA.

PLoS Pathog. 2015 Feb 6;11(2):e1004637. doi: 10.1371/journal.ppat.1004637. eCollection 2015 Feb.

16.

A replicating adenovirus capsid display recombinant elicits antibodies against Plasmodium falciparum sporozoites in Aotus nancymaae monkeys.

Karen KA, Deal C, Adams RJ, Nielsen C, Ward C, Espinosa DA, Xie J, Zavala F, Ketner G.

Infect Immun. 2015 Jan;83(1):268-75. doi: 10.1128/IAI.02626-14. Epub 2014 Nov 3.

17.

Vectored antibody gene delivery protects against Plasmodium falciparum sporozoite challenge in mice.

Deal C, Balazs AB, Espinosa DA, Zavala F, Baltimore D, Ketner G.

Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12528-32. doi: 10.1073/pnas.1407362111. Epub 2014 Aug 11.

18.

The chemokine receptor CXCR6 is required for the maintenance of liver memory CD8⁺ T cells specific for infectious pathogens.

Tse SW, Radtke AJ, Espinosa DA, Cockburn IA, Zavala F.

J Infect Dis. 2014 Nov 1;210(9):1508-16. doi: 10.1093/infdis/jiu281. Epub 2014 May 13.

19.

Fusion of antigen to a dendritic cell targeting chemokine combined with adjuvant yields a malaria DNA vaccine with enhanced protective capabilities.

Luo K, Zhang H, Zavala F, Biragyn A, Espinosa DA, Markham RB.

PLoS One. 2014 Mar 5;9(3):e90413. doi: 10.1371/journal.pone.0090413. eCollection 2014.

20.

Development of a chimeric Plasmodium berghei strain expressing the repeat region of the P. vivax circumsporozoite protein for in vivo evaluation of vaccine efficacy.

Espinosa DA, Yadava A, Angov E, Maurizio PL, Ockenhouse CF, Zavala F.

Infect Immun. 2013 Aug;81(8):2882-7. doi: 10.1128/IAI.00461-13. Epub 2013 May 28.

21.

Full-length Plasmodium falciparum circumsporozoite protein administered with long-chain poly(I·C) or the Toll-like receptor 4 agonist glucopyranosyl lipid adjuvant-stable emulsion elicits potent antibody and CD4+ T cell immunity and protection in mice.

Kastenmüller K, Espinosa DA, Trager L, Stoyanov C, Salazar AM, Pokalwar S, Singh S, Dutta S, Ockenhouse CF, Zavala F, Seder RA.

Infect Immun. 2013 Mar;81(3):789-800. doi: 10.1128/IAI.01108-12. Epub 2012 Dec 28.

22.

Adjuvant-like effect of vaccinia virus 14K protein: a case study with malaria vaccine based on the circumsporozoite protein.

Vijayan A, Gómez CE, Espinosa DA, Goodman AG, Sanchez-Sampedro L, Sorzano CO, Zavala F, Esteban M.

J Immunol. 2012 Jun 15;188(12):6407-17. doi: 10.4049/jimmunol.1102492. Epub 2012 May 21.

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